Axitinib

Anter

• Ma mua o ka lawe ʻana i ka axitinib,
• Hiki i nā Axitinib ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e loaʻa i ke kōkua olakino pilikia.
• Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

Hoʻohana wale ʻia ʻo Axitinib e mālama i ka carcinoma cell renal kiʻekiʻe (RCC, kahi ʻano o ke kanesa e hoʻomaka i nā hunaola o nā puʻupaʻa) i ka poʻe i mālama maikaʻi ʻole ʻia me kahi lāʻau ʻē aʻe. Hoʻohana ʻia ʻo Axitinib me ka hui pū me avelumab (Bavencio) a i ʻole pembrolizumab (Keytruda) e mālama ai i ka carcinoma kōkō ʻoi loa. Aia ʻo Axitinib i kahi papa o nā lāʻau i kapa ʻia nā kinase inhibitors. Hana ia ma ke kāpae ʻana i ka hana o kahi protein pono ʻole e hōʻailona ai i nā hunaola maʻi ʻaʻai e hoʻonui. Kōkua kēia i ka hoʻolohi a hoʻopau paha i ka hoʻolaha ʻana o nā hunaola maʻi ʻaʻai.

Hele mai ʻo Axitinib ma ke ʻano he papa e lawe ma ka waha. Lawe mau ʻia me ka ʻai ʻole a i ʻole ʻelua mau manawa i ka lā. Lawe i ke axitinib ma nā manawa like i kēlā me kēia lā, ma kahi o 12 mau hola ke kaʻawale. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pono i ke axitinib e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā papa i ke aniani o ka wai; mai hoʻokaʻawale, a nau aku, a hoka ʻole iā lākou.

Inā luaʻi ʻoe ma hope o ka lawe ʻana i ka axitinib, mai lawe i kahi lāʻau ʻē aʻe. E hoʻomau i kāu papa hana maʻamau.

E hoʻomaka paha kāu kauka iā ʻoe ma kahi lāʻau haahaa o axitinib a hoʻonui iki i kāu lāʻau, ʻaʻole ʻoi aku i hoʻokahi manawa i kēlā me kēia 2 pule. Aia kēia i ka maikaʻi o ka hana ʻana o ka lāʻau iā ʻoe a me nā hopena ʻē aʻe āu e ʻike ai. E kamaʻilio me kāu kauka e pili ana i kou ʻano i kāu mālama ʻana. E hoʻomau i ka lawe ʻana i ke axitinib ʻoiai inā maikaʻi ʻoe. Mai hōʻoki i ka lawe ʻana i ke axitinib me ke kamaʻilio ʻole ʻana me kāu kauka.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka axitinib,

• e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka axitinib, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa axitinib. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, a me nā mea hoʻopihaʻai pono ʻole āu e lawe nei a hoʻolālā paha e lawe. E ʻike pono i kekahi o kēia mau mea: bosentan (Tracleer); carbamazepine (Carbatrol, Epitol, Tegretol); clarithromycin (Biaxin, i Prevpac); itraconazole (Sporanox); ketoconazole (Nizoral); nā lāʻau e mālama ai i nā maʻi HIV / AID me atazanavir (Reyataz), efavirenz (Sustiva, ma Atripla), etravirine (Intelence), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir), a me saquinavir (Invirase); modafinil (Provigil); nafcillin; nefazodone; phenobarbital; phenytoin (Dilantin, Phenytek); rifabutin (Mycobutin); rifampin (Rifamate, Rifater); rifapentine (Priftin); nā lāʻau steroid e like me dexamethasone (Decadron); telithromycin (Ketek); a me voriconazole (Vfend). Nui paha nā lāʻau ʻē aʻe e launa pū paha me ka axitinib, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St John.
• e haʻi i kāu kauka inā he ʻeha kou i hōʻola ʻole, a i ʻole loaʻa a loaʻa paha iā ʻoe kahi pilikia kahe o ke kahe. kahe koko; ke koko kiʻekiʻe; he puʻuwai puʻuwai; mimikō; kiʻekiʻe pae kolesterol; kahe ana o ka ʻōpū i loko o ka ʻōpū a i ʻole nā ​​ʻōpū; maʻi ʻaʻai lolo; kahi pulmonary embolism (kōkuʻu koko i kou māmā); kahi hahau a kuhina paha (TIA); a puʻuwai paha; akepaʻa; aiʻole ka maʻi thyroid.
• E haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a inā ʻoe e hoʻolālā i kahi keiki i kahi keiki. Inā he wahine ʻoe, pono ʻoe e lawe i kahi hōʻike hāpai keiki ma mua o ka hoʻomaka ʻana o ka mālama ʻana a hoʻohana i ka kaohi hānau e pale ai i ka hāpai ʻana i kāu wā lapaʻau a no 1 pule ma hope o kāu hopena hope loa. Inā he kāne ʻoe, pono ʻoe a me kāu pakanā wahine e hoʻohana i ka kaohi hānau ma kāu wā e mālama ai a no 1 mau pule ma hope o kāu hopena hope loa. E kamaʻilio me kāu kauka e pili ana i nā hana kaohi hānau e holo pono nāu. Inā hāpai ʻoe a ʻo kāu hoa paha i ka lawe ʻana i ka axitinib, e kāhea i kāu kauka. Hoʻopilikia paha ʻo Axitinib i ka fetus.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. ʻAʻole pono ʻoe e hānai i ka wā o kāu mālama ʻana me axitinib a no 2 mau pule ma hope o kāu hopena hope loa.
• pono ʻoe e ʻike i kēia lāʻau i hoʻemi ai i ka momona i nā kāne a me nā wahine. E kamaʻilio me kāu kauka e pili ana i ka makaʻu o ka lawe ʻana i ka axitinib.
• inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o nā niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe ana ʻoe i ka axitinib. E haʻi aku kāu kauka iā ʻoe e hōʻoki i ka lawe ʻana i ka axitinib ma ka liʻiliʻi he 2 mau lā ma mua o kou ʻoki ʻana a ke palekana iā ʻoe e hoʻomaka hou i ka lawe ʻana i ke axitinib ma hope o kāu ʻoki.

Mai ʻai i ka hua waina a i ʻole inu i ka wai huaʻulu i ka wā e lawe ana i kēia lāʻau.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

Inā ʻoe e nalo i kahi mahele o axitinib, lele i kēlā lāʻau a lawe i kāu lāʻau aʻe i ka manawa maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hiki i nā Axitinib ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• pāhoehoe
• hoʻemi i ka makemake a i ʻole hiki ke ʻono i nā mea
• Kaumaha emi
• nausea
• ka luaʻi
• kōpaʻa
• luhi
• nāwaliwali
• e hoʻololi i ke kani o kou leo
• ʻulaʻula, ʻeha, numbness, tingling, a i ʻole ʻili a ʻili paha o ka ʻili ma kou mau lima a me kou mau wāwae
• ʻūhā
• ʻeha hui a ʻeha ʻeha paha
• ʻeha nā waha
• ʻeha ka ʻōpū
• puhi ka naʻau
• ʻeha poʻo
• ʻūpā
• hūwī
• ʻūlili
• ʻili maloʻo
• wela a anuanu paha
• ʻili mae
• kuʻi ka puʻuwai wikiwiki
• poho lauoho
• kani i nā pepeiao
• make wai
• hemorrhoids
• ʻeha a ʻokiʻoki ʻole e hoʻōla

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e loaʻa i ke kōkua olakino pilikia.

• ʻeha ka ʻōpū nui
• pokole o ka hanu
• pehu i nā lima a i ʻole nā ​​wāwae
• kahe koko ʻole ʻana a palapū paha
• pahu noho ʻeleʻele a lohi hoʻi
• koko ʻulaʻula i nā noho
• luaʻi koko
• mea luaʻi e like me ke kahua kope
• ʻeha ka umauma a i ʻole kaomi
• ʻeha ma nā lima, kua, ʻāʻī, a ʻāʻā
• pehu, palupalu, mehana, a ʻulaʻula o ka wāwae
• ʻōlohelohe ʻole a nawaliwali paha o ka maka, ka lima, a me ka wāwae (ʻoi loa ma kekahi ʻaoʻao o ke kino)
• huikau koke, pilikia e ʻōlelo a hoʻomaopopo paha
• pilikia pilikia i ka ʻike ʻana i hoʻokahi o nā maka ʻelua paha
• ka pilikia hele wawae, ʻōpau, nalo o ke kaulike a i ʻole ka hoʻohui ʻana
• ʻeha poʻo poʻo ʻole me ke kumu ʻole i ʻike ʻia
• ka hopu ʻana
• nalo o ka hihiʻo

Hoʻokumu paha ʻo Axitinib i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

• ʻūpā
• ka hopu ʻana
• kahe ana ke koko

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i ka axitinib. E nānā pinepine hoʻi kāu kauka i kou kaomi koko i kou wā e mālama ai me ka axitinib.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Inlyta^®