Mea Kākau: William Ramirez
Lā O Ka Hana: 16 Kepakemapa 2021
HōʻAno Hou I Ka Lā: 14 Nowemapa 2024
Anonim
Deferasirox (EXJADE), Deferoxamine, Deferiprone : Mechanisms of action (1/2)【USMLE/Pharmacology】
Wikiō: Deferasirox (EXJADE), Deferoxamine, Deferiprone : Mechanisms of action (1/2)【USMLE/Pharmacology】

Anter

Hoʻokumu paha ʻo Deferiprone i kahi hōʻemi o ka nui o nā hunaola keokeo i hana ʻia e kou iwi iwi. Kōkua nā hunaola koko keʻokeʻo i kou kino i ka hakakā ʻana i ka maʻi, no laila inā he helu haʻahaʻa kou o nā hunaola keʻokeʻo, aia kahi kiʻekiʻe o ka makaʻu e hoʻomohala ʻoe i kahi maʻi koʻikoʻi a weliweli paha i ke ola. E haʻi aku i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, no ka mea ʻo ka lawe ʻana i kekahi mau lāʻau ʻē aʻe a me deferiprone e hoʻonui ai i ka makaʻu e hoʻemi ʻia ka nui o ke kaukā koko. Inā ʻoe e ʻike i kekahi o nā ʻōuli o ka maʻi, e hoʻōki i ka lawe ʻana i ka deferiprone a kāhea koke aku i kāu kauka a i ʻole e loaʻa i ke kōkua olakino pōpilikia: ke kuni, ka ʻāʻī, nā ʻeha o ka waha, nā ʻōuli e like me ka flu, nā haʻalulu, a me nā haʻalulu nui.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha aku kāu kauka i kekahi mau hoʻokolohua keʻena hoʻokolohua, me nā hoʻokolohua e nānā ai i ka helu o ke koko keʻokeʻo ma mua o kou lapaʻau ʻana a ma hoʻokahi manawa i kēlā me kēia pule i kāu mālama ʻana.

E hāʻawi aku kāu kauka a kauka paha iā ʻoe i ka palapala ʻike hoʻomanawanui o ka mea hana (Ke alakaʻi lāʻau) ke hoʻomaka ʻoe i ka lāʻau me deferiprone a i kēlā me kēia manawa e hoʻopiha hou i kāu kauka. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.


E kamaʻilio me kāu kauka e pili ana i ka makaʻu (s) o ka lawe deferiprone.

Hoʻohana ʻia ʻo Deferiprone e hoʻoneʻe i ka nui o ka hao i loko o ke kino i ka poʻe i loaʻa i ka nui o ke kahe o ke koko e mālama i ka thalassemia (kahi ʻano hoʻoilina e hoʻoliʻiliʻi ai i nā hunaola ʻulaʻula) a ʻaʻole i lawa ka pōmaikaʻi mai nā hana ʻē aʻe no ka nui o ka hao. . Aia ʻo Deferiprone i kahi papa o nā lāʻau i kapa ʻia he chelators hao. Hana ia ma ka hoʻopili ʻana i ka hao i loko o ke kino i hiki ai ke excreted (wehe ʻia mai ke kino).

Hele mai ʻo Deferiprone ma ke ʻano he papaha e lawe ma ka waha. Lawe pinepine ʻia ia ʻekolu mau manawa i ka lā, i ke kakahiaka, i ke awakea o ka lā, a i ke ahiahi. Hiki ke lawe ʻia ʻo Deferiprone me ka ʻole o ka meaʻai, akā ʻo ka lawe ʻana me ka ʻai e kōkua paha ia e pale aku i ka nausea i hiki i ka lāʻau. Lawe iā deferiprone ma kahi o ka manawa like (s) i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe iā deferiprone e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.


Inā hoʻokomo kāu mahele lāʻau i ka hapalua o ka papa, e hoʻokaʻawale pono i kahi papa ma ka māka helu.

Hiki i kāu kauka ke hoʻoponopono i kāu lāʻau o deferiprone i kēlā me kēia 2 a i 3 mau mahina e pili ana i nā hopena hoʻokolohua o kāu hale hana.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana iā deferiprone,

  • e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka deferiprone, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa deferiprone. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, a me nā mea hoʻopihaʻaiʻai āu e lawe nei a hoʻolālā paha e lawe. E hoʻomaopopo pono e ʻōlelo i nā diuretics (nā pila wai). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
  • inā ʻoe e lawe i nā antacids, multivitamins, a i ʻole nā ​​mea hoʻohui hao a zinc paha, e lawe iā lākou i 4 mau hola ma mua a i ʻole 4 mau hola ma hope o kou lawe ʻana i ka deferiprone.
  • e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, keu hoʻi ka puaʻi o ka waiū.
  • e haʻi i kāu kauka inā loaʻa a i ʻole loaʻa paha iā ʻoe kahi wā QT hoʻolōʻihi (kahi pilikia puʻuwai laha ʻole e hiki ai ke hōʻeha i ka puʻuwai ʻole, maʻule, a make koke paha), kahi puʻuwai lohi, puʻuwai puʻuwai a i ʻole nā ​​pilikia puʻuwai ʻē aʻe, kahi pae haʻahaʻa o ka potassium a me ka magnesium. i kou kōkō, a i ʻole ka maʻi puʻupaʻa a i ʻole ate.
  • e haʻi i kāu kauka inā hāpai ʻoe, hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Pono ʻoe e hoʻohana i ka kaohi hānau i ʻole ʻoe e hāpai i ka wā o kāu mālama ʻana me deferiprone. E kamaʻilio me kāu kauka e pili ana i ke ʻano hana o ka kaohi hānau āu e hoʻohana ai. Inā hāpai ʻoe i ka lawe ʻana iā deferiprone, e kāhea koke i kāu kauka. Hoʻopilikia paha ʻo Deferiprone i ka fetus.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.


E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Deferiprone i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • nausea
  • ka luaʻi
  • puʻuwai puʻuwai
  • ʻeha ka ʻōpū
  • pāhoehoe
  • hoʻonui a hoʻēmi paha i ka makemake
  • loaʻa kaupaona
  • ʻeha ma nā lima, nā wāwae, hoʻi a me nā hono
  • ʻeha poʻo
  • ʻulaʻula a ʻeleʻele paha o ka ihi

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

  • ʻulaʻula ʻulaʻula a i ʻole nā ​​kuhū, keu hoʻi ma ka hapa haʻahaʻa o ke kino
  • hives
  • pehu a puni nā maka
  • wikiwiki a kuʻi paha i ka puʻuwai puʻuwai
  • ʻūpā
  • ʻālohilohi
  • maule ana
  • ka hopu ʻana

Hoʻokumu paha ʻo Deferiprone i nā hopena ʻē aʻe. Kāhea i kāu kauka inā loaʻa iā ʻoe kekahi pilikia maʻamau ke lawe nei ʻoe i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou.No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i nā hoʻokolohua lab e nānā i ka pane o kou kino iā deferiprone.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

  • Ferriprox
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