Lapatinib

Anter

• Ma mua o ka lawe ʻana i ka lapatinib,
• Hoʻokumu paha ʻo Lapatinib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻoaʻo PALAPALA a i ʻole ka ʻĀINA WAIKU SPECIAL, e kelepona koke i kāu kauka:
• Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

Hiki i ka Lapatinib ke hōʻeha i ke akepaʻa i hiki ke hōʻeha a hoʻoweliweli paha i ke ola. Hiki ke hana i ka hōʻino o ke ake i nā lā he nui a i ʻole ka hala ʻana o kekahi mau mahina ma hope o ka hoʻomaka ʻana o ka lapaʻau me lapatinib. E haʻi i kāu kauka inā loaʻa a loaʻa paha ʻoe i ka maʻi ate. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka: ʻili, melemele o ka ʻili a i ʻole nā ​​maka, mimi ʻeleʻele, ʻeha ma ka ʻaoʻao ʻākau o luna o ka ʻōpū, kahe ʻana o ke kahe a i ʻole ka palapū, a i ʻole nā ​​noho polū a ʻeleʻele paha.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha aku kāu kauka i kekahi mau hoʻokolohua keʻena hoʻokolohua ma mua a i kāu wā e mālama ai e ʻike inā paha e hōʻeha a hōʻeha ʻia paha kou akepa e lapatinib.

E kamaʻilio me kāu kauka e pili ana i ka makaʻu o ka lawe ʻana i ka lapatinib.

Hoʻohana ʻia ʻo Lapatinib me capecitabine (Xeloda) e mālama ai i kekahi ʻano maʻi ʻaʻai o ka umauma holomua i nā poʻe i mālama mua ʻia me nā lāʻau chemotherapy ʻē aʻe. Hoʻohana pū ʻia ʻo Lapatinib me letrozole (Femara) e mālama ai i kekahi ʻano maʻi ʻaʻai o ka umauma i nā wahine postmenopausal (nā wahine i ʻike i ka loli o ke ola; ka hopena o nā manawa o ka menstrual) i pāhola ʻia i nā ʻāpana ʻē aʻe o ke kino. Aia ʻo Lapatinib i kahi papa o nā lāʻau i kapa ʻia nā kinase inhibitors. Hana ia ma ke kāpae ʻana i ka hana o ka protein pono ʻole e hōʻailona ai i nā hunaola maʻi ʻaʻai e hoʻonui. Kōkua kēia i ka hōʻoki a hoʻolohi paha i ka hoʻolaha ʻana o nā hunaola maʻi ʻaʻai.

Hele mai ʻo Lapatinib ma ke ʻano he papa e lawe ma ka waha. Lawe ʻia ia i hoʻokahi manawa i ka lā, ma ka liʻiliʻi he 1 hola ma mua a i ʻole 1 hola ma hope o ka pāʻina ʻana. Ke hoʻohana ʻia ka lapatinib e mālama i ka maʻi ʻaʻai umauma holomua a metastatic paha, hāʻawi pinepine ʻia ia i kēlā me kēia lā i nā lā 1 a 21 (me capecitabine i nā lā 1 a 14) o kahi pōʻaiapuni 21 mau lā. E hana hou ʻia ke kalapona e like me ka ʻōlelo a kāu kauka. Ke hoʻohana ʻia ka lapatinib e mālama i ka maʻi ʻaʻai umauma i nā wahine postmenopausal, hāʻawi pinepine ʻia hoʻokahi manawa i kēlā me kēia lā me ka letrozole. E lawe i nā papa lapatinib āpau no kāu mahele lāʻau o kēlā me kēia lā i hoʻokahi manawa i kēlā me kēia lā; mai hoʻokaʻawale i nā papa e lawe i nā ʻāpana ʻokoʻa. E lawe i ka lapatinib ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe i ka lapatinib e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā papa holoʻokoʻa; mai hoʻokaʻawale, a nau aku, a hoka ʻole iā lākou.

E hoʻonui a hoʻoliʻiliʻi paha kāu kauka i kāu kauā o lapatinib i kāu mālama ʻana. Aia kēia i ka maikaʻi o ka hana ʻana o ka lāʻau iā ʻoe a me nā hopena ʻē aʻe āu e ʻike ai. E hoʻomau i ka lawe ʻana i ka lapatinib inā maikaʻi ʻoe. Mai hōʻoki i ka lawe ʻana i ka lapatinib me ke kamaʻilio ʻole ʻana me kāu kauka.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka lapatinib,

• e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka lapatinib, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa lapatinib. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, a me nā mea hoʻopihaʻaiʻai āu e lawe nei a hoʻolālā paha e lawe. E kuhikuhi pono i kekahi o kēia mau mea: kekahi antibiotic e like me clarithromycin (Biaxin, i Prevpac), erythromycin (EES, E-Mycin, Erythrocin), moxifloxacin (Avelox), rifabutin (Mycobutin), rifampin (Rifadin, i Rifamate, i Rifater, Rimactane), rifapentine (Priftin), sparfloxacin (Zagam) (ʻaʻole loaʻa ma ka US), a me telithromycin (Ketek); nā antifungals e like me itraconazole (Sporanox), ketoconazole (Nizoral), a me voriconazole (Vfend); calcium blockers blockers e like me amlodipine (Norvasc, in Caduet a me Lotrel), diltiazem (Cardizem, Dilacor, Tiazac, a me nā mea ʻē aʻe), felodipine (Plendil, ma Lexxel), nifedipine (Adalat, Nifedical XL, Procardia, a me nā mea ʻē aʻe), nisoldipine (Sular) , a me verapamil (Calan, Isoptin, Verelan, nā mea ʻē aʻe); cisapride (Propulsid) (ʻaʻole loaʻa ma ka U.S.); dexamethasone (Decadron, Dexpak); kekahi mau lāʻau no ke kaumaha e like me nefazodone; kekahi mau lāʻau chemotherapy me daunorubicin (Cerubidine, DaunoXome), doxorubicin (Adriamycin, Doxil, Rubex), epirubicin (Ellence), idarubicin (Idamycin), tamoxifen (Nolvadex), valrubicin (Valstar), vinblastine, a me vincine; kekahi mau lāʻau no ka maʻi pale maʻi (HIV) a i ʻole loaʻa i ka maʻi maʻi maʻi maʻi (AIDS) me atazanavir (Reyataz), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, ma Kaletra), a me saquinavir (Invirase); nā lāʻau no ke kuʻi puʻuwai ʻole e like me amiodarone (Cordarone), disopyramide (Norpace), dofetilide (Tikosyn), procainamide (Procanbid), quinidine, a me sotalol (Betapace, Betapace AF, Sorine); kekahi mau lāʻau no ka hopu ʻana e like me carbamazepine (Carbatrol, Epitol, Tegretol), phenobarbital (Luminal), a me phenytoin (Dilantin, Phenytek); pimozide (Orap); a me thioridazine. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Hiki paha i nā lāʻau ʻē aʻe ke launa pū me ka lapatinib, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka a me kāu kauka lāʻau he aha nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St.
• e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa paha iā ʻoe kahi puʻuwai lohi, wikiwiki, a i ʻole maʻamau. kahi wā QT hoʻolōʻihi (kahi pilikia puʻuwai laha ʻole e hiki ai ke hōʻeha i ka puʻuwai ʻole, maʻule, a make koke paha); kahi pae haʻahaʻa o ka magnesium a potassium paha i loko o kou koko; aiʻole maʻi puʻuwai a puʻuwai paha.
• e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. Pono ʻoe e lawe i kahi hōʻike hāpai ma mua o ka hoʻomaka ʻana i ka lāʻau. Inā he wahine ʻoe i hiki ke hāpai, pono ʻoe e hoʻohana i ka kaohi hānau pono i kou wā e mālama ai a no 1 mau pule ma hope o kāu hopena hope loa. Inā he kāne ʻoe me kāu hoa wahine i hiki ke hāpai, pono ʻoe e hoʻohana i ka kaohi hānau kūpono i kou wā e mālama ai a no 1 mau pule ma hope o kāu hopena hope loa. E kamaʻilio me kāu kauka e pili ana i nā ʻano hana hānau hiki iā ʻoe ke hoʻohana i kāu wā o kāu mālama ʻana. Inā hāpai ʻoe i ka lawe ʻana i ka lapatinib, e kāhea koke i kāu kauka. Hoʻopilikia paha ʻo Lapatinib i ka fetus.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū a i ʻole hoʻolālā e hānai. ʻAʻole pono ʻoe e hānai i ka wā e lawe ana i ka lapatinib a no 1 mau pule ma hope o kāu hopena hope loa.
• pono ʻoe e ʻike ʻo ka lapatinib ke kumu pinepine i ka maʻi diarrhea, ka mea hiki ke koʻikoʻi. Kāhea i kāu kauka inā loaʻa ʻoe i ka maʻi pākē i ka lawe ʻana i ka lapatinib. E haʻi paha kāu kauka iā ʻoe e inu i nā wai he nui, e hoʻololi i kāu papaʻai, a lawe i ka lāʻau e kāohi ai i ka palahī a pale aku ai i ka make wai (ka nui o ka wai mai kou kino). Kāhea koke i kāu kauka inā ʻike ʻoe i kekahi o nā ʻōuli o ka make wai ʻana: ka make wai loa, ka waha maloʻo a me / a i ʻole ka ʻili, hoʻemi i ka urination, nā maka pihoʻi, a me ka puʻuwai puʻuwai wikiwiki.

Mai ʻai i ka hua waina a i ʻole inu i ka wai huaʻulu i ka wā e lawe ana i kēia lāʻau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai i kēlā lā. Eia nō naʻe, inā ʻaʻole ʻoe e hoʻomanaʻo a hiki i ka lā aʻe, inā ʻaʻole hiki iā ʻoe ke hoʻomanaʻo inā ʻoe i lawe i ka lāʻau, a inā e luaʻi ʻoe i kāu lāʻau, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Lapatinib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• nausea
• ka luaʻi
• puʻuwai puʻuwai
• ʻeha ma nā lehelehe, waha, a ʻāʻī paha
• nalo ʻai ʻole
• ʻulaʻula, ʻeha, nūmū, a i ʻole nā ​​kani lima a me nā wāwae
• ʻili maloʻo
• ʻeha ma nā lima, nā wāwae, a i ʻole ke kua
• paʻakikī e hiamoe a hiamoe paha

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻoaʻo PALAPALA a i ʻole ka ʻĀINA WAIKU SPECIAL, e kelepona koke i kāu kauka:

• pokole o ka hanu
• ʻūhū maloʻo
• ke kuʻi nei i ka momona a i ʻole ka mucus koko
• wikiwiki, kūlike ʻole, a kuʻi paha i ka puʻuwai puʻuwai
• nāwaliwali
• ka pehu o nā lima, ka wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo
• hūwī
• fiva
• ʻili a ʻiliʻili paha

Lapatinib paha e loli i ke ala a kou puʻuwai e kuʻi ai a pauma i ke koko ma o kou kino. E nānā pono kāu kauka iā ʻoe e ʻike inā pili ka lapatinib i kou puʻuwai. E kamaʻilio me kāu kauka e pili ana i ka makaʻu o ka lawe ʻana i ka lapatinib.

Hoʻokumu paha ʻo Lapatinib i nā hopena ʻē aʻe. Kāhea i kāu kauka inā loaʻa iā ʻoe kekahi pilikia maʻamau ke lawe nei ʻoe i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

• pāhoehoe
• ka luaʻi

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Tykerb^®