ʻO Sorafenib

Anter

• Ma mua o ka lawe ʻana i ka sorafenib,
• Hoʻokumu paha ʻo Sorafenib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:
• Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

Hoʻohana ʻia ʻo Sorafenib e mālama i ka carcinoma kōkō ʻoi loa (RCC; kahi ʻano maʻi ʻaʻai e hoʻomaka i nā puʻupaʻa). Hoʻohana ʻia ʻo Sorafenib e mālama i ka carcinoma hepatocellular (kahi ʻano maʻi ʻaʻai ate) ʻaʻole hiki ke mālama ʻia me ke kaha ʻana a me kekahi ʻano o ka maʻi ʻaʻai thyroid i pāhola ʻia i nā ʻāpana ʻē aʻe o ke kino a ʻaʻole hiki ke mālama ʻia me ka iodine radioactive. Aia ʻo Sorafenib i kahi papa o nā lāʻau i kapa ʻia ʻo nā kinase inhibitors. Hana ia ma ke kāpae ʻana i ka hana o kahi protein pono ʻole e hōʻailona ai i nā hunaola maʻi ʻaʻai e hoʻonui. Kōkua kēia i ka hōʻoki ʻana i nā hunaola maʻi ʻaʻai.

Hele mai ʻo Sorafenib ma ke ʻano he papa e lawe ma ka waha. Lawe ʻia ia i ʻelua mau manawa i ka lā. Lawe ʻia ʻo Sorafenib me ka ʻai ʻole, 1 hola ma mua a i ʻole 2 mau hola ma hope o ka pāʻina ʻana. Lawe i ka sorafenib ma nā manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pololei i ka sorafenib e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E hoʻopau i nā papa i ka wai. Mai hoʻokaʻawale, a nau, a ʻāpala paha iā lākou.

Hiki i kāu kauka ke hōʻemi i kāu lāʻau o sorafenib i kou wā e hoʻomaʻamaʻa ai, a i ʻole e haʻi paha iā ʻoe e hoʻomaha iki a paʻa paha i ka lawe ʻana i ka sorafenib no kekahi manawa inā ʻike ʻoe i nā hopena ʻaoʻao. E haʻi pono i kāu kauka i kou ʻano i kou wā e mālama ai me sorafenib.

E hoʻomau i ka lawe sorafenib ʻoiai ʻoe e manaʻo maikaʻi. Mai hōʻoki i ka lawe ʻana i ka sorafenib me ke kamaʻilio ʻole ʻana me kāu kauka.

ʻAʻole loaʻa ʻo Sorafenib i nā hale kūʻai lāʻau. Hiki iā ʻoe ke loaʻa i ka sorafenib ma o ka leka uila wale nō mai kahi kauka lāʻau lapaʻau kūikawā. E nīnau i kāu kauka inā he nīnau kāu e pili ana i ka loaʻa ʻana o kāu lāʻau.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka sorafenib,

• e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka sorafenib, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa sorafenib. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• E haʻi i kāu kauka inā loaʻa ʻoe i ka maʻi ʻaʻa maʻi a ke loaʻa nei ʻoe i ka lāʻau me karboplatin (Paraplatin) a me paclitaxel (Abraxane, Onxol, Taxol) a i ʻole gemcitabine (Gemzar) a me cisplatin (Platinol). E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka sorafenib inā loaʻa ʻoe i ka maʻi ʻaʻa maʻi a ke loaʻa nei iā ʻoe kēia mau lāʻau.
• e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, a me nā mea hoʻopihaʻaiʻai āu e lawe nei a hoʻolālā paha e lawe. E ʻike pono i kekahi o kēia mau mea: kekahi mau lāʻau no arrhythmia e like me amiodarone (Nexterone, Pacerone), dofetilide (Tikosyn), dronedarone (Multaq), procainamide, quinidine (i Nuedexta), a me sotalol (Betapace, Sorine, Sotylize); nā anticoagulants (nā mea lahilahi o ke koko) e like me warfarin (Coumadin, Jantoven); carbamazepine (Equetro, Tegretol, Teril); dexamethasone; ibutilide (Corvert); irinotecan (Camptosar); neomycin; phenobarbital; phenytoin (Dilantin, Phenytek); rifabutin (Mycobutin); aiʻole rifampin (Rifadin, Rimactane). Nui paha nā lāʻau ʻē aʻe e launa pū paha me sorafenib, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St.
• e haʻi i kāu kauka inā loaʻa paha iā ʻoe ke kiʻekiʻe o ke koko kiʻekiʻe, nā pilikia kahe ʻana o ka umauma, ʻeha o ka puʻuwai, nā pilikia o ka puʻuwai, QT hoʻolōʻihi (kahi puʻuwai puʻuwai kūpono ʻole e hiki ai i ka nāwaliwali, nalowale o ka ʻike, hopu ʻana, a make koke paha), potasiuma, kalipuna, a i ʻole magnesium i loko o kou koko, kahi puʻuwai kūlike ʻole, puʻuwai puʻuwai, nā pilikia kīwī ʻē aʻe ma mua o ka maʻi ʻaʻai kidney, a i ʻole nā ​​pilikia ʻē aʻe ma mua o ka maʻi ʻaʻai ate.
• e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. Pono ʻoe e lawe i kahi hōʻike hāpai ma mua o ka hoʻomaka ʻana i ka lāʻau. Inā he wahine ʻoe i hiki ke hāpai, pono ʻoe e hoʻohana i ka kaohi hānau pono i kou wā e mālama ai a no 6 mau mahina ma hope o kāu hopena hope loa. Inā he kāne ʻoe me kāu hoa wahine i hiki ke hāpai, pono ʻoe e hoʻohana i ka kaohi hānau pono i kou wā e mālama ai a no 3 mau mahina ma hope o kāu hopena hope loa. E kamaʻilio me kāu kauka e pili ana i nā hana kaohi hānau e holo pono nāu. Inā hāpai ʻoe i ka lawe ʻana i ka sorafenib, e kāhea koke i kāu kauka. Hoʻopilikia paha ʻo Sorafenib i ka fetus.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū a i ʻole hoʻolālā e hānai. ʻAʻole pono ʻoe e hānai i ka wā e lawe ana i ka sorafenib a no 2 mau pule ma hope o kāu hopena hope loa.
• inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o nā niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe ana ʻoe i ka sorafenib.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E haʻalele i ka lāʻau i haʻalele ʻia a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Sorafenib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• luhi
• nāwaliwali
• ʻulaʻula ʻili
• poho lauoho
• ʻūlili
• ʻili maloʻo a ihi paha
• nalo ʻai ʻole
• kōpaʻa
• pāhoehoe
• waha maloo
• Kaumaha emi
• ʻeha pū
• numbness, ʻeha a ʻūlū paha i nā lima a me nā wāwae
• ʻeha poʻo

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:

• ʻāpā ʻaʻano ʻole a hoʻokahe koko paha
• ʻeke a me / a i ʻole nā ​​pā noho
• koko ʻulaʻula i nā noho
• luaʻi koko
• mea luaʻi e like me ke kahua kope
• fiva
• ʻeha ka ʻōpū nui
• nausea
• ka luaʻi
• ʻeha ka umauma
• pokole o ka hanu
• paupauaho a maʻule paha
• sweating nui loa
• wikiwiki, kuʻi, a i ʻole kuʻi puʻuwai puʻuwai
• ʻeha poʻo poʻo loa
• huikau
• nā hoʻololi i ka hihiʻo
• ka hopu ʻana
• hūwī
• ʻulaʻula, ʻeha, pehu a palapū paha i nā poho o nā lima a i ʻole nā ​​kapuwaʻi o nā wāwae
• ʻili a ʻili hoʻi i ka ʻili
• hives
• ʻūlili
• ʻulaʻula ʻili
• ʻeha nā waha
• mimi ʻeleʻele
• melemele o ka ʻili a me nā maka
• ʻeha ma ka ʻaoʻao ʻākau o luna o ka ʻōpū

Hoʻokumu paha ʻo Sorafenib i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

• pāhoehoe
• hū a i ʻole nā ​​pilikia ʻili ʻē aʻe

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i ka sorafenib. E nānā pū kāu kauka i kou kaomi koko i kēlā me kēia pule i loko o nā pule ʻeono mua o kou mālama ʻana a laila mai kēlā me kēia manawa e pono ai.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Nexavar^®