ʻO Deferasirox

Anter

• E lawe i nā papa deferasirox no ke kau ʻana (Exjade), e hāhai i kēia mau kaʻina hana:
• Ma mua o ka lawe ʻana i ka deferasirox,
• Hoʻokumu paha ʻo Deferasirox i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i ʻōlelo ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka:
• Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

Hiki i ka Deferasirox ke kumu i ka hōʻeha koʻikoʻi a i ʻole ke ola e hōʻino ai i nā puʻupaʻa. ʻOi aku ka makaʻu āu e hoʻomāhuahua ai i nā puʻupaʻa inā loaʻa iā ʻoe nā kūlana olakino he nui, a i ʻole maʻi nui ʻoe no ka maʻi maʻi koko. E haʻi i kāu kauka inā loaʻa ʻoe a i ʻole loaʻa i ka maʻi puʻupaʻa. E haʻi paha kāu kauka iā ʻoe mai lawe i ka deferasirox. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka: hoʻemi i ka urination, ka pehu ʻana i nā kuʻekuʻe wāwae, nā wāwae, a me nā wāwae, ka luhi nui, ka hanu nui, a me ka huikau. No nā keiki e lawe ana i kēia lāʻau, aia ka nui o ka makaʻu e hoʻomohala ʻoe i nā pilikia o ke konā inā loaʻa ʻoe i ka maʻi i ka wā e lawe ana i ka deferasirox a ulu i ka maʻi palahū, ka luaʻi, ke kuni, a i ʻole ka hōʻoki ʻana i ka inu ʻana i nā wai maʻamau. Kāhea koke i kāu kauka inā ʻike ʻoe i kekahi o kēia mau ʻōuli.

Hoʻokumu pū paha ʻo Deferasirox i nā hōʻino koʻikoʻi a ola paha i ke ake. ʻOi aku ka makaʻu āu e hoʻomāhuahua ai i ka hōʻino o ke ake inā ʻoi aku ʻoe ma mua o 55 mau makahiki, a i ʻole inā he maʻi olakino ʻē aʻe kou. E haʻi i kāu kauka inā loaʻa a loaʻa paha ʻoe i ka maʻi ate. Inā hoʻomohala ʻoe i kekahi o nā ʻōuli aʻe, e kāhea koke i kāu kauka: melemele o ka ʻili a i ʻole nā ​​maka, nā ʻōuli e like me ka flu, nele i ka ikaika, nalo o ka makemake ʻole, ʻeha ma ka ʻaoʻao ʻākau i luna o ka ʻōpū, a i ʻole ʻeha a me ka hoʻokahe koko ʻole.

Hoʻokumu pū paha ʻo Deferasirox i ke kahe o ke kahe i loko o ka ʻōpū a i ʻole nā ​​ʻōpū. ʻOi aku ka nui o ka makaʻu e hoʻomohala ʻoe i ke kahe o ka ʻōpū a i ʻole nā ​​ʻōpū inā ʻelemakule ʻoe, a maʻi nui paha mai ke ʻano o ke koko. E haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa i kahi pae haʻahaʻa o nā platelet (kahi ʻano o ke koko e pono ai e kaohi i ke kahe ʻana o ke kahe), a i ʻole inā e lawe ʻoe i kekahi o nā lāʻau aʻe: anticoagulants (nā mea lahilahi o ke koko) e like me warfarin (Coumadin , Jantoven); aspirin a i ʻole nā ​​lāʻau anti-inflammatory nonsteroidal (NSAIDs) e like me ibuprofen (Advil, Motrin, a me nā mea ʻē aʻe) a me naproxen (Aleve, Naprosyn, a me nā mea ʻē aʻe); kekahi mau lāʻau e hoʻoikaika ai i nā iwi me ka alendronate (Binosto, Fosamax), etidronate, ibandronate (Boniva), pamidronate, risedronate (Actonel, Atelvia), a me ka waikawa zoledronic (Reclast, Zometa); aiʻole nā ​​steroid e like me dexamethasone, methylprednisolone (A-methapred, Depo-medrol, Medrol, Solu-medrol), a i ʻole prednisone (Rayos). Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka: ʻo ka ʻeha ʻana o ka ʻōpū, ka luaʻi ʻulaʻula a i ʻole ke nānā aku e like me ka papa kope, ke koko ʻulaʻula ʻulaʻula i loko o nā noho, a i ʻole nā ​​papa kuʻi.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha aku kāu kauka i nā hoʻokolohua hale hana ma mua a i ka wā o kāu mālama ʻana e ʻike pono ia he palekana no ʻoe e lawe i ka deferasirox a ʻike inā ke hoʻomohala nei ʻoe i kēia mau hopena ʻaoʻao koʻikoʻi.

Hoʻohana ʻia ʻo Deferasirox e mālama i nā mākua a me nā keiki ʻo 2 mau makahiki a ʻoi paha i nui ka hao i ko lākou kino no ka mea ua loaʻa iā lākou ka nui o ke kahe o ke koko. Hoʻohana ʻia ia e mālama i nā mākua a me nā keiki he 10 mau makahiki a ʻoi paha ka nui o ka hao i loko o ko lākou kino ma muli o kahi maʻi koko i kapa ʻia ʻo thalassemia hilinaʻi ʻole ʻia (NTDT). Aia ʻo Deferasirox i kahi papa o nā lāʻau i kapa ʻia he chelators hao. Hana ia ma ka hoʻopili ʻana i ka hao i loko o ke kino i hiki ai ke excreted (wehe ʻia mai ke kino) i nā feces.

Hele mai ʻo Deferasirox ma ke ʻano he papa, nā granula, a me kahi papa no ke kau ʻana (kahi papa e hoʻoheheʻe ʻia i ka wai) e lawe ma ka waha. Lawe ʻia ia ma ka ʻōpū hakahaka i hoʻokahi manawa i ka lā, ma ka liʻiliʻi he 30 mau minuke ma mua o ka ʻai ʻana, hiki ke lawe ʻia i nā papa a me nā granula me kahi pāʻina māmā e like me ka muffin English palaoa āpau me ka jelly a me ka waiū skim, a i ʻole ka sanwich turkey liʻiliʻi ma palaoa palaoa holoʻokoʻa. Lawe iā deferasirox ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe iā deferasirox pololei e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

Hoʻokomo ʻia nā huahana deferasirox ʻokoʻa e ke kino ma nā ʻano like ʻole a ʻaʻole hiki ke pani ʻia i kekahi i kekahi. Inā pono ʻoe e hoʻololi i hoʻokahi huahana deferasirox i kahi huahana ʻē aʻe, pono paha i kāu kauka e hoʻoponopono i kāu lāʻau. I kēlā me kēia manawa ke loaʻa iā ʻoe kāu lāʻau lapaʻau, e nānā pono inā ua loaʻa iā ʻoe ka huahana deferasirox i kuhikuhi ʻia nāu. E noi i kāu kauka inā ʻaʻole maopopo iā ʻoe ua loaʻa iā ʻoe ka lāʻau kūpono.

E hoʻopau i nā papa deferasirox (Jadenu) me ka wai a me nā wai ʻē aʻe. Inā pilikia ʻoe i ka ale ʻana i ka papa, hiki iā ʻoe ke wāwahi i ka papa a kāwili pū ʻia me kahi meaʻai palupalu e like me ka yogurt a i ʻole ka applesauce ma mua koke o ka lawe ʻana. Eia naʻe, mai haki i ka papa 90 mg (Jadenu) me ka hoʻohana ʻana i kahi hāmeʻa ʻūlū ʻoihana i hoʻopili ʻia i nā kihi.

E lawe i nā granules deferasirox (Jadenu), e kāpīpī i nā granula i kahi meaʻai palupalu e like me ka yogurt a i ʻole ka applesauce ma mua koke o ka lawe ʻana.

E lawe i nā papa deferasirox no ke kau ʻana (Exjade), e hāhai i kēia mau kaʻina hana:

1. E hoʻonā mau i nā papa no ka hoʻomaha ʻana i ka wai ma mua o kou lawe ʻana iā lākou. Mai nau wale a ale i nā papa no ka hoʻomaha holoʻokoʻa.
2. Inā ʻoe e lawe ana ma lalo o 1000 mg o deferasirox, e hoʻopiha i kahi kīʻaha hapa (ma kahi o 3.5 oz / 100 mL) me ka wai, wai ʻāpala, a wai ʻalani paha. Inā ʻoe e lawe ana ma mua o 1000 mg o deferasirox, hoʻopiha i kahi kīʻaha (ma kahi o 7 oz / 200 mL) me ka wai, wai ʻāpala, a wai ʻalani paha. Inā ʻaʻole maopopo iā ʻoe pehea ka deferasirox e lawe ai, e nīnau i kāu kauka a kauka paha.
3. E kau i ka helu o nā papa i haʻi ʻia e kāu kauka e lawe i loko o ke kīʻaha.
4. E hoʻowali i ka wai no 3 mau minuke e hoʻopau loa i nā pā. E mānoanoa paha ka hui ʻana i ka wā e hoʻowali ʻoe.
5. Inu koke ka wai.
6. E hoʻohui i kahi wai liʻiliʻi i ke kīʻaha ʻole a hoʻowali. E kīloi i ke kīʻaha e hoʻonā i kekahi lāʻau i koe i loko o ke kīʻaha a i ʻole i ka mea hoʻouluulu.
7. Inu i ke koena o ka wai.

Hiki i kāu kauka ke hoʻoponopono i kāu lāʻau o deferasirox ʻaʻole ʻoi aku ma mua o hoʻokahi manawa i kēlā me kēia 3 a 6 mau mahina, e like me nā hopena o kāu hoʻokolohua hoʻokolohua.

Wehe ʻo Deferasirox i ka hao keu mai kou kino me ka lohi o ka holo ʻana o ka manawa. E hoʻomau i ka lawe ʻana i ka deferasirox ʻoiai inā maikaʻi ʻoe. Mai hōʻoki i ka lawe ʻana i ka deferasirox me ke kamaʻilio ʻole ʻana me kāu kauka.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka deferasirox,

• e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka deferasirox, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa deferasirox, granules, a i ʻole nā ​​papa no ka hoʻomaha. E noi i kāu kauka a kauka paha no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, nā mea hoʻopihaʻai, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe E hoʻomaopopo pono e ʻōlelo i nā lāʻau i helu ʻia i ka ʻARlelo Aʻo IMPORTANT a me kekahi o kēia mau mea: alosetron (Lotronex), aprepitant (Cinvanti, Emend), budesonide (Entocort, Pulmicort, Uceris, ma Symbicort), buspirone, cholestyramine (Prevalite), colesevelam (Welchol), colestipol (Colestid), conivaptan (Vaprisol), cyclosporine (Gengraf, Neoral, Sandimmune), darifenacin (Enablex), darunavir (Prezista, i Prezcobix), dasatinib (Sprycel), dihydroergotamine (DHE 45, Migranal) (Multaq), duloxetine (Cymbalta), eletriptan (Relpax), eplerenone (Inspra), ergotamine (Ergomar, ma Cafergot, Migergot), everolimus (Afinitor, Zortress), felodipine, fentanyl (Actiq, Duragesic, Subsyicas, kekahi) (Arnuity Ellipta, Flovent, ma Breo Ellipta, Advair), nā kaola pale hormonal (nā lāʻau kaohi hānau, nā pā, nā apo, a i ʻole nā ​​injection), indinavir (Crixivan), lopinavir (i Kaletra), lovastatin (Altoprev), lurasidone (Latuda), maraviroc (Selzentry), midazolam, nisoldipine (Sular), paclitax el (Abraxane, Taxol), phenytoin (Dilantin, Phenytek), phenobarbital, pimozide (Orap), quetiapine (Seroquel), quinidine (i Nuedexta), ramelteon (Rozerem), repaglinide (Prandin, i Prandimet), rifampin (Rimin, , ma Rifamate, ma Rifater), ritonavir (Norvir, ma Kaletra, Technivie, Viekira Pak), saquinavir (Invirase), sildenafil (Revatio, Viagra), simvastatin (Flolopid, Zocor, ma Vytorin), siroliumus (Rapamune), tacrolimus ( Astagraf, Envarsus, Prograf), theophylline (Theo-24), ticagrelor (Brilinta), tipranavir (Aptivus), tizanidine (Zanaflex), triazolam (Halcion), tolvaptan (Samsca), a me vardenafil (Levitra, Staxyn). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• inā ʻoe e lawe i nā antacid i loaʻa i ka aluminika e like me Amphojel, Alternagel, Gaviscon, Maalox, a i ʻole Mylanta, lawe iā lākou i 2 mau hola ma mua a ma hope paha o ka deferasirox.
• e haʻi i kāu kauka he aha nā huahana counter āu e lawe nei, keu hoʻi i ka melatonin, a i ʻole nā ​​mea hoʻohui caffeine.
• e haʻi i kāu kauka inā loaʻa ʻoe i ka myelodysplastic syndrome (kahi pilikia koʻikoʻi me ka iwi o ka iwi i hiki ke loaʻa i ka maʻi ʻaʻai nui), a i ʻole ka maʻi ʻaʻai. E haʻi paha kāu kauka iā ʻoe mai lawe i ka deferasirox.
• E haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Inā hāpai ʻoe i ka lawe ʻana iā deferasirox, e kāhea i kāu kauka.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E lawe i ka lāʻau i hala ma hope i ka lā, ma ka liʻiliʻi he 2 mau hola ma hope o kāu pāʻina hope loa a me 30 mau minuke ma mua o ka ʻai ʻana. Eia nō naʻe, inā kokoke i ka manawa no ka hopena aʻe a i ʻole inā ʻaʻole hiki iā ʻoe ke lawe i ka deferasirox ma kahi ʻōpū nele, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Deferasirox i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• ʻeha ka ʻōpū
• nausea
• ka luaʻi
• pāhoehoe

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i ʻōlelo ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka:

• poho lohe
• pilikia pilikia ʻike
• ʻehu, hives, ʻili a ihi paha i ka ʻili, ka wela, nā pehu lymph pehu
• pilikia i ka hanu ʻana a i ʻole ke ale ʻana; pehu o ka maka, ʻāʻī, elelo, lehelehe, a i ʻole nā ​​maka; hulahula
• ʻāpā ʻaʻano ʻole a hoʻokahe koko paha

Hoʻokumu paha ʻo Deferasirox i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

• melemele o ka ʻili a me nā maka
• ʻeha ma ka ʻaoʻao ʻākau o luna o ka ʻōpū
• ʻāpā ʻaʻano ʻole a hoʻokahe koko paha
• nele i ka ikaika
• nalo ʻai ʻole
• nā ʻōuli like flu
• pāhoehoe
• nausea
• ka luaʻi
• hoʻemi urination
• pehu o nā wāwae a i ʻole nā ​​kuʻekuʻe wāwae

Mālama i nā manawa āpau me kāu kauka. Pono ʻoe i ka hoʻolohe ʻana a me nā hoʻāʻo ʻana o ka maka ma mua o ka hoʻomaka ʻana o deferasirox a hoʻokahi manawa i ka makahiki i ka wā e lawe ana i kēia lāʻau.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Hoʻouka^®
• ʻO Jadenu^®