Hale haʻuki

Anter

• ʻAʻole lawa nā hōʻike e hōʻike i ka pono no ...
• Nā mālama a me nā ʻōlelo aʻoaʻo kūikawā:

ʻO Gymnema kahi ulu lāʻau ulu e ulu ana ma India a me ʻApelika. Hoʻohana ʻia ka lau i lāʻau. ʻO Gymnema kahi moʻolelo lōʻihi o ka hoʻohana ʻana i ka lāʻau Ayurvedic India. ʻO ka inoa Hindi no ka hale hoʻoikaika kino, ʻo ia ka mea "luku i ke kō."

Hoʻohana ka poʻe i ka gymnema no ka maʻi diabetes, ka pohō kaumaha, a me nā kūlana ʻē aʻe, akā ʻaʻohe hōʻike ʻepekema maikaʻi e kākoʻo i kēia mau hoʻohana.

Nā Laʻau Laʻau Kūlohelohe Kūlohelohe nā helu kūpono e pili ana i nā hōʻike ʻepekema e like me ka pālākiō e hiki mai ana: Ka maikaʻi, ka hopena maikaʻi, ka hopena maikaʻi, ka hopena maikaʻi ʻole, ka maikaʻi ʻole, ka maikaʻi ʻole, a me ka lawa ʻole o nā hōʻike i ka helu.

Nā helu kūpono no GYMNEMA penei:

ʻAʻole lawa nā hōʻike e hōʻike i ka pono no ...

• Diabetes. Hōʻike ka noiʻi mua i ka lawe ʻana i ka gymnema ma ka waha a me ka lāʻau insulin a i ʻole ka maʻi diabetic hiki ke hoʻomaikaʻi i ke kaohi kō kō i nā poʻe me ka maʻi diabetes 1 a ʻano 2 paha.
• Metabolic maʻi pale. Hōʻike ka noiʻi mua i ka lawe ʻana i ka gymnema no 12 mau pule hiki ke hōʻemi i ke kaumaha o ke kino a me ka papa kuhikuhi o ke kino i ka poʻe kaumaha me ka maʻi metabolic Akā ʻaʻole ʻike ʻia ka gymnema e kōkua me ke kaohi kō kō a hoʻomaikaʻi paha i nā kiʻekiʻe o ka cholesterol i kēia mau poʻe.
• Kaumaha emi. Hōʻike ka noiʻi mua ʻana i ka lawe ʻana i nā gymnema no 12 mau pule hiki ke hōʻemi i ke kaumaha o ke kino a me ka papa kuhikuhi o ke kino i kekahi poʻe i kaumaha kaupaona. Hōʻike pū kekahi kahi noiʻi mua i ka lawe ʻana i kahi hui gymnema, hydroxycitric acid, a me ka chromium i hoʻopaʻa ʻia e ka niacin e ka waha hiki ke hōʻemi i ke kaumaha o ke kino i ka poʻe i kaumaha a momona paha.
• Cough.
• Hoʻonui i ka excretion mimi (diuretic).
• Malaria.
• Metabolic maʻi pale.
• Nahu nahesa.
• Palupalu i ka pahu (laxative).
• Hoʻonāukiuki digestion.

Pono hou nā hōʻike e hōʻike i ka gymnema no kēia mau hoʻohana.

Loaʻa i ka Gymnema nā mea e hoʻemi i ka lawe ʻana o ke kō mai ka ʻōpū. Hiki paha i ka Gymnema ke hoʻonui i ka nui o ka insulin i loko o ke kino a hoʻonui i ka ulu ʻana o nā hunaola i ka pancreas, kahi kahi o ke kino e hana ʻia ai ka insulin.

Hale haʻuki ʻo SAFE MAU PONO ke lawe ʻia e ka waha kūpono no 20 mau mahina.

Nā mālama a me nā ʻōlelo aʻoaʻo kūikawā:

Hāpai a me ka hānai umauma: ʻAʻole lawa ka ʻike pono e pili ana i ka palekana o ka lawe ʻana i nā hale hoʻoikaika kino inā hāpai ʻoe a i ʻole ka hānai ʻana i ka umauma. Noho ma ka ʻaoʻao palekana a pale i ka hoʻohana.

Diabetes: Hiki i ka Gymnema ke hoʻohaʻahaʻa i nā kiʻekiʻe o ke kō i ke kanaka me ka maʻi kō. E nānā no nā hōʻailona o ke kō kō (haʻahaʻa i ke kō kō a haʻahaʻa) a nānā pono i kāu kō kō i ke kō inā loaʻa ka maʻi diabetes a hoʻohana i ka gymnema.

ʻOki kino: Pā paha ka gymnema i nā pae kō kō a hiki ke hoʻopili i ka kaohi kō kō i ka wā a ma hope o nā kaʻina hana. Hoʻoki i ka hoʻohana ʻana i ka gymnema ma ka liʻiliʻi he 2 mau pule ma mua o ke kaukoki i hoʻonohonoho ʻia.

Kānāwai

E akahele me kēia hui ʻana.

Insulina

Hoʻoemi paha ka gymnema i ke kō kō. Hoʻohana ʻia ka insulin e hoʻoliʻiliʻi i ke kō kō. Lawe paha i ka gymnema me ka insulin i haʻahaʻa loa i kāu kō kō. E nānā pono i kāu kō kō. Pono e hoʻololi i ka hopena o kāu insulin.

Ua hoʻololi ʻia nā lāʻau e ke ake (Cytochrome P450 1A2 (CYP1A2) substrates)

Hoʻololi ʻia kekahi mau lāʻau a wāwahi ʻia e ke ake. E hoʻemi paha ka gymnema i ka wikiwiki o ka haki o ke ake i kekahi mau lāʻau. Lawe i ka hale haʻuki me kekahi o nā lāʻau i hoʻololi ʻia a wāwahi ʻia e ke akepaʻa e hoʻonui ai i nā hopena a me nā hopena ʻaoʻao o kekahi mau lāʻau. Ma mua o ka lawe ʻana i ka hale hoʻoikaika kino, e kamaʻilio me kāu kauka inā mālama ʻoe i nā lāʻau i hoʻololi ʻia e ke ake.

ʻO kekahi mau lāʻau i hoʻololi ʻia e ke akepaʻa, ʻo ia nō ʻo clozapine (Clozaril), cyclobenzaprine (Flexeril), fluvoxamine (Luvox), haloperidol (Haldol), imipramine (Tofranil), mexiletine (Mexitil), olanzapine (Zyprexa), pentazocine (Talwin) (Inderal), tacrine (Cognex), theophylline, zileuton (Zyflo), zolmitriptan (Zomig), a me nā mea ʻē aʻe.

Hoʻololi nā lāʻau i ke ake (Cytochrome P450 2C9 (CYP2C9) substrates)

Hoʻololi ʻia kekahi mau lāʻau a wāwahi ʻia e ke ake. Hiki paha i ka Gymnema ke hoʻololi i ka wikiwiki o ka haki o ke ake i kekahi mau lāʻau. Lawe i ka hale hoʻoikaika kino me kekahi mau lāʻau i hoʻololi ʻia a wāwahi ʻia e ke akepaʻa e loli paha i nā hopena a me nā hopena ʻaoʻao o kekahi mau lāʻau. Ma mua o ka lawe ʻana i ka hale hoʻoikaika kino, e kamaʻilio me kāu kauka inā mālama ʻoe i nā lāʻau i hoʻololi ʻia e ke ake.

ʻO kekahi mau lāʻau i hoʻololi ʻia e ke akepaʻa, ʻo ia hoʻi ʻo amitriptyline (Elavil), diazepam (Valium), zileuton (Zyflo), celecoxib (Celebrex), diclofenac (Voltaren), fluvastatin (Lescol), glipizide (Glucotrol), ibuprofen (Advil, Motrin) , irbesartan (Avapro), losartan (Cozaar), phenytoin (Dilantin), piroxicam (Feldene), tamoxifen (Nolvadex), tolbutamide (Tolinase), torsemide (Demadex), warfarin (Coumadin), a me nā mea ʻē aʻe.

Nā lāʻau no ka maʻi kō (Antidiabetes lāʻau)

ʻO nā mea kōkua gymnema e like me ka hoʻohaʻahaʻa ʻana i ke kō kō i nā poʻe me ka maʻi kō. Hoʻohana ʻia nā lāʻau diabetes e hoʻohaʻahaʻa i ke kō kō. ʻO ka lawe ʻana i ka hale hoʻoikaika kino me nā lāʻau maʻi diabetes e hoʻohaʻahaʻa ai i kāu kō kō. E nānā pono i kāu kō kō. Pono e hoʻololi i ka mahele lāʻau o kāu lāʻau diabetes.

ʻO kekahi mau lāʻau i hoʻohana ʻia no ka maʻi kō me glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), a me kekahi .

Phenacetin

Hōʻoki ke kino i ka phenacetin e kāpae aku iā ia. E hoʻemi paha ka gymnema i ka wikiwiki o ka haki o ke kino i ka phenacetin. Lawe i ka gymnema ʻoiai e lawe ana i ka phenacetin e hoʻonui paha i nā hopena a me nā hopena ʻē aʻe o ka phenacetin. Ma mua o ka lawe ʻana i gymnema, e kamaʻilio me kāu kauka inā mālama ʻoe i ka phenacetin.

Tolbutamide

Haki ke kino i ka tolbutamide e kāpae iā ia. E hoʻonui paha ka hale haʻuki i ka wikiwiki o ka haki o ke kino i ka tolbutamide. Lawe i ka gymnema ʻoiai e lawe i ka tolbutamide e hōʻemi paha i nā hopena o tolbutamide. Ma mua o ka lawe ʻana i ka hale hoʻoikaika kino, e kamaʻilio me kāu kauka inā mālama ʻoe i ka tolbutamide.

Mea liʻiliʻi

E makaʻala me kēia hui pū.

Hoʻololi nā lāʻau i ke ake (Cytochrome P450 3A4 (CYP3A4) substrates)

Hoʻololi ʻia kekahi mau lāʻau a wāwahi ʻia e ke ake. E hoʻemi paha ka gymnema i ka wikiwiki o ka haki o ke ake i kekahi mau lāʻau. Lawe i ka hale haʻuki me kekahi o nā lāʻau i hoʻololi ʻia e ke akepaʻa e hoʻonui ai i nā hopena a me nā hopena ʻaoʻao o kekahi mau lāʻau. Ma mua o ka lawe ʻana i gymnema, e kamaʻilio me kāu kauka inā mālama ʻoe i nā lāʻau i hoʻololi ʻia e ke ake.

ʻO kekahi mau lāʻau i hoʻololi ʻia e ke akepaʻa, ʻo ia hoʻi ka lovastatin (Mevacor), clarithromycin (Biaxin), cyclosporine (Neoral, Sandimmune), diltiazem (Cardizem), estrogens, indinavir (Crixivan), triazolam (Halcion), a me nā mea ʻē aʻe he nui.

ʻO nā lau nahele a me nā mea hoʻopili e hoʻoliʻiliʻi ai i ke kō kō

Hiki i ka gymnema extract ke hoʻohaʻahaʻa i ke kō kō. Ke hoʻohana nei ia me nā mea kanu a me nā mea hoʻopili ʻē aʻe i loaʻa kēia hopena like e hoʻonui paha i ka makaʻu o ke kō kō i loko o kekahi poʻe. ʻO kekahi o kēia mau huahana e laʻa me ka alpha-lipoic acid, melon ʻawaʻawa, chromium, māiʻuʻu diabolō, fenugreek, kālika, guar gum, chestnut lio, ginseng Panax, psyllium, ginseng Siberian, a me nā mea ʻē aʻe.

ʻAikika ʻolika

Hiki i ka gymnema ke hoʻoliʻiliʻi i ka lawe ʻana o ke kino i ka waikawa oleic.

ʻAʻole ʻike ʻia nā launa me nā meaʻai.

ʻO ka mahele kūpono o ka hale haʻuki e pili ana i nā kumu like ʻole e like me ka makahiki o ka mea hoʻohana, olakino, a me nā ʻano ʻē aʻe. I kēia manawa ʻaʻole lawa ka ʻike ʻepekema e hoʻoholo ai i kahi pae kūpono o nā lāʻau no ka hale hoʻoikaika kino. E hoʻomanaʻo i ka pono ʻole o ka palekana i nā huahana kūlohelohe a hiki i nā dosages ke koʻikoʻi. E mālama pono i nā ʻōkuhi pili i nā lepili huahana a nīnau i kāu kauka lāʻau a i ʻole kauka a i ʻole ʻoihana olakino ʻē aʻe ma mua o ka hoʻohana ʻana.

ʻO Australian Cowplant, Chi geng teng, Gemnema Melicida, Gimnema, Gur-Mar, Gurmar, Gurmarbooti, ​​Gurmur, Gymnema sylvestre, Gymnéma, Gymnéma Sylvestre, Madhunashini, Merasingi, Meshasring, Meshashringi, Miracle Plant, Periploca sylvestris, Periploca of the , Waldschlinge, Vishani.

E aʻo hou aʻe ai pehea i kākau ʻia ai kēia ʻatikala, e ʻoluʻolu e ʻike i ka Nā Laʻau Laʻau Kūlohelohe Kūlohelohe ʻano hana.

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2. ʻO Vaghela M, Sahu N, Kharkar P, Pandita N. I ka vivo pharmacokinetic hui pū ʻia e ka ethanolic extract o gymnema sylvestre me CYP2C9 (tolbutamide), CYP3A4 (amlodipine) a me CYP1A2 (phenacetin) i nāʻiole.Hana ʻo Chem Biol. 2017 Dec 25; 278: 141-151. Nānā kiʻi ʻole.
3. Rammohan B, Samit K, Chinmoy D, et al. ʻO ka cytochrome P450 enzyme modulate e gymnema sylvestre: kahi loiloi palekana palekana e LC-MS / MS. ʻO Pharmacogn Mag. 2016 Jul; 12 (Pākuʻi 4): S389-S394. Nānā kiʻi ʻole.
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6. ʻO Nakamura Y, Tsumura Y, Tonogai Y, Shibata T. Hoʻonui ʻia ka execce steroid fecal i loko o nāʻiole e ka lawelawe waha ʻana o nā waikawa gymnemic i loko o nā lau Gymnema sylvestre. ʻO J Nutr 1999; 129: 1214-22. Nānā kiʻi ʻole.
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8. Arunachalam KD, Arun LB, Annamalai SK, Arunachalam AM. Nā waiwai anticancer kūpono o nā hui bioactive o Gymnema sylvestre a me kāna nanoparticles kālā biofunctionalized. Int J Nanomedicine. 2014; 10: 31-41. Nānā kiʻi ʻole.
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11. Kamble B, Gupta A, Moothedath I, Khatal L, Janrao S, Jadhav A, et al. Nā hopena o ka Gymnema sylvestre extract ma nā pharmacokinetics a me nā pharmodnamnamics o glimepiride i nā ʻiole diabetic i hoʻokomo ʻia i ka streptozotocin. Hana ʻo Chem Biol. 2016; 245: 30-8. Nānā kiʻi ʻole.
12. Murakami, N, Murakami, T, Kadoya, M, a me nā mea āpau. ʻO nā mea i loaʻa i ka hypoglycemic hou ma "gymnemic acid" mai Gymnema sylvestre. ʻO Chem Pharm Bull 1996; 44: 469-471.
13. ʻO Sinsheimer JE, Rao GS, a me McIlhenny HM. ʻO nā mea kūmole mai Gymnema sylvestre e haʻalele iā V. Hoʻokaʻawale a me ka hōʻike mua o nā gymnemic acid. ʻO J Pharm Sci 1970; 59: 622-628.
14. Wang LF, Luo H, Miyoshi M, a me et al. Ka hopena hoʻohiehie o ka gymnemic acid ma ka lawe ʻana o ka ʻōpū o ka oleic acid i nāʻiole. Hiki iā J Physiol Pharmacol 1998; 76: 1017-1023.
15. ʻO Terasawa H, Miyoshi M, a me Imoto T. Nā hopena o ka lawelawe manawa lōʻihi o Gymnema sylvestre wai-ʻoki ma nā ʻano o ke kino, plasma glucose, triglyceride serum, koleke kolesterol a me ka insulin i nāʻiole momona Wistar. Yonago Acta Med 1994; 37: 117-127.
16. ʻO Bishayee, A a me Chatterjee, M. Hypolipidaemic a me nā hopena antiatherosclerotic o gymnema waha sylvestre R. Br. hānai lau i nā ʻiole albino hānai i kahi papa momona momona. Phytother Res 1994; 8: 118-120.
17. ʻO Tominaga M, Kimura M, Sugiyama K, a me et al. Nā hopena o seishin-renshi-in a me Gymnema sylvestre ma ke kūpaʻa ʻana o ka insulin i nā ʻiole diabetic i hoʻokomo ʻia i loko o streptozotocin. Hoʻomaʻamaʻa ʻo Diabet Res Clin 1995; 29: 11-17.
18. ʻO Gupta SS a me Variyar MC. Nā hoʻokolohua hoʻokolohua e pili ana i ka diabetes pituitary IV. Ka hopena o ka Gymnema sylvestre a me Coccinia indica e kūʻē i ka hyperglycemia pane o somatotrophin a me nā corticotrophin hormones. ʻO Indian J Med Res 1964; 52: 200-207.
19. ʻO Chattopadhyay RR. Hiki i ke ʻano hana o ka hopena antihyperglycemic o ka Gymnema sylvestre leaf extract, Mahele I. Gen Pharm 1998; 31: 495-496.
20. Shanmugasundaram ERB, Gopinath KL, Shanmugasundaram KR, a me et al. Hiki ke hoʻoulu hou ʻia o nā mokupuni ʻo Langerhans i nā ʻiole streptozotocin-diabetic i hāʻawi ʻia i nā extract lau Gymnema sylvestre. ʻO J Ethnopharm 1990; 30: 265-279.
21. Shanmugasundaram KR, Panneerselvam C, Samudram P, a me et al. Hoʻololi ka enzyme a me ka hoʻohana ʻana o ka glucose i nā lāpaki diabetic: ka hopena o Gymnema sylvestre, R.Br. ʻO J Ethnopharm 1983; 7: 205-234.
22. ʻO Srivastava Y, Bhatt HV, Prem AS, a me et al. ʻO ka hypoglycemic a me nā mea hoʻolōʻihi ola o ka Gymnema sylvestre leaf extract i nāʻiole diabetic. ʻO Israel J Med Sci 1985; 21: 540-542.
23. Shanmugasundaram ERB, Rajeswari G, Baskaran K, a me et al. Hoʻohana o ka Gymnema sylvestre leaf extract i ka kaohi o ke kō glucose i ka insulin-dependant diabetes mellitus. ʻO J Ethnopharm 1990; 30: 281-294.
24. Khare AK, Tondon RN, a me Tewari JP. ʻO ka hana Hypoglycaemic o kahi lāʻau ʻōiwi (Gymnema sylvestre, "Gurmar") i nā kānaka maʻamau a me ka diabetic. ʻO Indian J Physiol Pharm 1983; 27: 257-258.
25. ʻO Kothe A a me Uppal R. Nā hopena Antidiabetic o Gymnema sylvestre ma NIDDM - kahi noiʻi pōkole. ʻO Indian J Homeopath Med 1997; 32 (1-2): 61-62, 66.
26. Baskaran, K, Ahamath, BK, Shanmugasundaram, KR, a me nā mea āpau. Ka hopena Antidiabetic o kahi lau i lawe ʻia mai Gymnema sylvestre i loko o nā mea maʻi diabetes-dependant non-insulin-dependant. ʻO J Ethnopharm 1990; 30: 295-305.
27. Yoshikawa, M., Murakami, T., Kadoya, M., Li, Y., Murakami, N., Yamahara, J., a me Matsuda, H. Nā mea kūʻai lāʻau lapaʻau. IX. ʻO nā mea kāohi i ka lawe ʻana o ka glucose mai nā lau o Gymnema sylvestre R. BR. (Asclepiadaceae): nā hale o nā gymnemosides a me b. ʻO Chem. ʻO Bull Bull. (Tokyo) 1997; 45: 1671-1676. Nānā kiʻi ʻole.
28. Okabayashi, Y., Tani, S., Fujisawa, T., Koide, M., Hasegawa, H., Nakamura, T., Fujii, M., a me Otsuki, M. Ka hopena o Gymnema sylvestre, R.Br. ma ka homeostasis glucose i nāʻiole. Hoʻomaʻamaʻa Diabetes Res Clinic 1990; 9: 143-148. Nānā kiʻi ʻole.
29. Jiang, H. [Nā holomua i ke aʻo ʻana ma nā mea hypoglycemic o Gymnema sylvestre (Retz.) Schult]. Zhong.Yao Cai. 2003; 26: 305-307. Nānā kiʻi ʻole.
30. ʻO Gholap, S. a me Kar, A. Nā hopena o ka Inula racemosa root a me nā Gymnema sylvestre extract leaf i ka rula o ka Corticosteroid induced diabetes mellitus: ke komo pū ʻana o nā hormones thyroid. Pharmazie 2003; 58: 413-415. Nānā kiʻi ʻole.
31. Ananthan, R., Latha, M., Pari, L., Ramkumar, K. M., Baskar, C. G., a me Bai, V. N. Ka hopena o ka Gymnema montanum ma ka glucose koko, ka insulin insulin, a me nā enzyme metabolic carbohydrate i nāʻiole diabetic i hoʻokomo ʻia alloxan. ʻO J Med Food 2003; 6: 43-49. Nānā kiʻi ʻole.
32. Xie, J. T., Wang, A., Mehendale, S., Wu, J., Aung, H. H., Dey, L., Qiu, S., a me Yuan, C. S. Nā hopena anti-diabetic o kā Gymnema yunnanense i unuhi ʻia. ʻO Pharmacol Res 2003; 47: 323-329. Nānā kiʻi ʻole.
33. ʻO Porchezhian, E. a me Dobriyal, R. M. He hōʻike ākea e pili ana i ka holomua o ka Gymnema sylvestre: chemistry, pharmacology a me nā patent. Pharmazie 2003; 58: 5-12. Nānā kiʻi ʻole.
34. Preuss, H. G., Garis, R. I., Bramble, J. D., Bagchi, D., Bagchi, M., Rao, C. V., a me Satyanarayana, S. Efficacy o kahi novel calcium / potassium salt o (-) - hydroxycitric acid i ke kaupaona kaohi. Int.J Clin.Pharmacol.Res. 2005; 25: 133-144. Nānā kiʻi ʻole.
35. ʻO Preuss HG, Bagchi D, Bagchi M, et al. Nā hopena o kahi unuhi kūlohelohe o (-) - hydroxycitric acid (HCA-SX) a me ka hui pū ʻana o HCA-SX a me ka chromium i hoʻopaʻa ʻia me ka niacin a me ka Gymnema sylvestre i ka lilo o ke kaupaona. ʻO Diabetes Obes Metab 2004; 6: 171-180. Nānā kiʻi ʻole.
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