Hōʻike Tensilon

ʻO ka hōʻike Tensilon kahi ala e kōkua ai i ka diagnose myasthenia gravis.

Hāʻawi ʻia kahi lāʻau i kapa ʻia ʻo Tensilon (i kapa ʻia hoʻi ʻo edrophonium) a i ʻole kahi lāʻau dummy (placebo hana ʻole) ma kēia hōʻike. Hāʻawi ka mea mālama ola i ka lāʻau lapaʻau ma o kekahi o kou mau uaua (intravenously, ma o ka IV). Hāʻawi ʻia ʻoe i kahi lāʻau i kapa ʻia atropine ma mua o ka loaʻa ʻana iā Tensilon i ʻole ʻoe e ʻike e loaʻa ana iā ʻoe ka lāʻau.

E noi ʻia ʻoe e hana i kekahi neʻe i nā mākala pinepine a pinepine, e like me ke keʻa ʻana a me ka hele ʻole ʻana i kou mau wāwae a i ʻole ke ala ʻana mai kahi noho i kahi noho. E nānā ka mea hāʻawi inā hoʻomaikaʻi ka Tensilon i kou ikaika i nā mākala. Inā loaʻa iā ʻoe ka nāwaliwali o ka maka a i ʻole nā ​​mākala maka, e nānā pū ʻia ka hopena o ka Tensilon ma kēia.

E hana hou ʻia paha ka hōʻike a loaʻa paha iā ʻoe nā hoʻokolohua Tensilon ʻē aʻe e kōkua ai e haʻi i ka ʻokoʻa ma waena o myasthenia gravis a me nā kūlana ʻē aʻe.

ʻAʻole pono ka hoʻomākaukau kūikawā. E hāhai i nā ʻōlelo aʻoaʻo a kāu mea hāʻawi e pili ana i ka hoʻomākaukau.

E ʻike ʻoe i kahi kui kuʻi ʻoi i ka hoʻokomo ʻia ʻana o ka nila IV. Hoʻokumu paha ka lāʻau i kahi ʻano o ka ʻū ʻana o ka ʻōpū a i ʻole ka manaʻo iki o ka hoʻonui ʻana o ka puʻuwai, keu hoʻi inā ʻaʻole hāʻawi ʻia ka atropine ma mua.

Kōkua ka hōʻike:

• Hōʻailona myasthenia gravis
• E haʻi i ka ʻokoʻa ma waena o myasthenia gravis a me nā ʻano lolo a me nā ʻano ʻōnaehana like ʻole
• Nānā i ka mālama ʻana me nā lāʻau anticholinesterase waha

E hana ʻia paha ka hōʻike no nā kūlana e like me Lambert-Eaton Syndrome. ʻO kēia kahi maʻi kahi e kamaʻilio hewa ai ma waena o nā ʻalalā a me nā mākala e alakaʻi ai i ka nāwaliwali o nā mākala.

I nā poʻe he nui me ka myasthenia gravis, e hoʻomaikaʻi maikaʻi ka nāwaliwali o ka mākala ma hope o ka loaʻa ʻana iā Tensilon. He mau minuke wale nō ka hoʻomaikaʻi. No kekahi ʻano myasthenia, hana paha ʻo Tensilon i ka nāwaliwali.

Ke hele a maikaʻi loa ka maʻi e pono ai ka lapaʻau (pilikia myasthenic), aia kahi hoʻomaikaʻi pōkole i ka ikaika o nā mākala.

Ke loaʻa ka overdose o anticholinesterase (cholinergic crisis), e hoʻonāwaliwali ʻo Tensilon i ke kanaka.

ʻO ka lāʻau i hoʻohana ʻia i ka wā o ka hoʻāʻo e kumu i nā hopena ʻaoʻao, me ka maʻule ʻana a me ka hanu ʻole ʻana. ʻO kēia ke kumu e hana ʻia ai ka hōʻike e kahi mea hoʻolako i kahi hoʻonohonoho olakino.

Myasthenia gravis - hōʻike hoʻowalewale

• Māluhiluhi Muscle

Chernecky CC, Berger BJ. Hōʻike Tensilon - diagnostic. I: Chernecky CC, Berger BJ, hua. Nā Hoʻokolohua Laboratory a me nā kaʻina hana Diagnostic. ʻElua huaʻōlelo St Louis, MO: Elsevier Saunders; 2013: 1057-1058.

Sanders DB, Guptill JT. Nā maʻi o ka hoʻoili neuromuscular. I: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, eds. ʻO Bradley's Neurology i ka hana lapaʻau. ʻEpekema 7 Piladelapia, PA: Elsevier; 2016: chap 109.