17-OH progesterone
17-OH progesterone kahi hōʻike koko e ana i ka nui o ka progesterone 17-OH. ʻO kēia kahi hōmona i hana ʻia e nā adrenal glands a me nā aʻa wahine.
Pono kahi laʻana koko. ʻO ka hapanui o nā manawa, huki ʻia ke koko mai kahi aa i waiho ʻia ma loko o ka kuʻe lima a i ʻole ka hope o ka lima.
I nā pēpē a i ʻole nā keiki ʻōpio, hiki ke hoʻohana ʻia kahi mea ʻoi i kapa ʻia he lancet e hou i ka ʻili.
- Hōʻiliʻili ke koko i loko o kahi kīʻaha kīʻaha liʻiliʻi i kapa ʻia he pipette, a i ʻole ma kahi pāheʻe a i ʻole ka papa hoʻāʻo.
- Hoʻokomo ʻia kahi bandage ma luna o kahi e kū ai ke kahe ʻana o ke kahe.
Hiki i nā lāʻau he nui ke hoʻopilikia i nā hopena hōʻike koko.
- E haʻi aku kāu mea mālama ola inā pono ʻoe e hōʻoki i ka lawe ʻana i nā lāʻau i mua o ka loaʻa ʻana o kēia hōʻike.
- Mai kū a hoʻololi paha i kāu mau lāʻau me ke kamaʻilio ʻole mua ʻana i kāu mea hāʻawi.
Hiki paha iā ʻoe ke ʻeha iki a i ʻole ke kuʻi ke hoʻokomo ʻia o ka nila. Hiki paha iā ʻoe ke hāwele i kahi kani ma ka pūnaewele ma hope o ka huki ʻia ʻana o ke koko.
ʻO ka hoʻohana nui o kēia hoʻāʻo e nānā i nā pēpē no kahi maʻi hoʻoilina i hoʻopili ʻia i ka momona adrenal, i kapa ʻia ʻo hyperplasia adrenal adrenal (CAH). Hana pinepine ʻia ia i nā pēpē i hānau ʻia me nā ʻōiwi o waho e nānā pono ʻole e like me ke keikikāne a kaikamahine paha.
Hoʻohana ʻia kēia ho'āʻo e ʻike i ka poʻe e hoʻomohala i nā ʻōuli o CAH ma hope o ke ola, kahi ʻano i kapa ʻia nonplassical adrenal hyperplasia.
E ʻōlelo paha kahi mea hāʻawi i kēia hoʻāʻo no nā wahine a i ʻole mau kaikamahine i loaʻa nā ʻano kāne e like me:
- ʻO ka ulu nui o ka lauoho i nā wahi kahi e ulu ai nā kāne makua i ka lauoho
- Leo hohonu a hoʻonui paha i ka nui o nā mākala
- Ka nele o ka menses
- Hoʻoipo
ʻOkoʻa nā waiwai maʻamau a me nā mea maʻamau no nā pēpē i hānau ʻia me ke kaumaha o ka hānau haʻahaʻa. Ma ke ʻano laulā, nā hopena maʻamau penei:
- ʻO nā pēpē ma mua o 24 mau hola - ma lalo o 400 a 600 nanograms no deciliter (ng / dL) a i ʻole 12.12 a 18.18 nanomoles i kēlā me kēia lita (nmol / L)
- ʻO nā keiki ma mua o ka ʻōpio ma kahi o 100 ng / dL a i ʻole 3.03 nmol / L
- Nā mākua - ma lalo o 200 ng / dL a i ʻole 6.06 nmol / L
Hiki ke loli iki nā pae waiwai maʻamau i waena o nā hale hana ʻokoʻa. E kamaʻilio i kāu mea hāʻawi e pili ana i ke ʻano o kāu mau hopena hōʻike.
Hōʻike nā laʻana ma luna i nā ana maʻamau no nā hopena o kēia mau hoʻāʻo. Hoʻohana kekahi mau keʻena hoʻokolohua i nā ana like ʻole a i ʻole hoʻokolohua i nā hoʻohālikelike like ʻole.
ʻO ke kiʻekiʻe kiʻekiʻe o ka progesterone 17-OH ma muli o:
- Nā Tumors o ke kelala adrenal
- ʻO hyperplasia adrenal congenital (CAH)
I nā pēpē me CAH, pae ka pae 17-OHP mai ka 2000 a i ka 40,000 ng / dL a i ʻole 60.6 a i ka 1212 nmol / L. I nā mākua, ʻoi aku ka kiʻekiʻe ma mua o 200 ng / dL a i ʻole 6.06 nmol / L ma muli o ka nonplassical adrenal hyperplasia.
E kuhi paha kāu mea hāʻawi i kahi hōʻike ACTH inā aia ka pae progesterone 17-OH ma waena o 200 a 800 ng / dL a i ʻole 6.06 a 24.24 nmol / L.
17-hydroxyprogesterone; Progesterone - 17-OH
ʻO Guber HA, Farag AF. ʻO ka loiloi o ka hana endocrine. I: McPherson RA, Pincus MR, hua. ʻO kā Henry's Clinical Diagnosis a me Management e nā Laboratory Methods. 23rd Ed. St Louis, MO: Elsevier; 2017: chap 24.
ʻO Rey RA, ʻo Josso N. Diagnosis a me ka mālama ʻana i nā maʻi o ka ulu moekolohe. I: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Makua a Pediatric. ʻEpekema 7 Piladelapia, PA: Elsevier Saunders; 2016: chap 119.
Keʻokeʻo PC. ʻO ka hyperplasia adrenal Congenital a me nā maʻi e pili ana. I: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. ʻO Puka Textbook of Pediatrics ʻo Nelson. 21st ed. Piladelapia, PA: Elsevier; 2020: chap 594.