Hōʻike hormone ulu
ʻO ke ana ʻana o ka hōmona ulu e ana i ka nui o ka hormone ulu i ke koko.
Hana ka pituitary gland i ka hormone ulu, kahi e ulu ai kahi keiki. Aia kēia gland ma ke kumu o ka lolo.
Pono kahi laʻana koko.
Hāʻawi paha kāu mea mālama ola iā ʻoe i nā ʻōlelo kūikawā e pili ana i ka mea āu e hiki ai a i ʻole hiki ʻole ke ʻai ma mua o ka hoʻāʻo.
Ke hoʻokomo ʻia ke kui kele e huki i ke koko, manaʻo kekahi poʻe i ka ʻeha kaulike. ʻIke wale kekahi i kahi ʻōniʻu a i ʻole kui. Ma hope, loaʻa paha i kahi kūpikipiki a i ʻole ka ʻūlū iki. Hele koke kēia.
Hiki ke nānā ʻia kēia hormona inā he ʻano maʻamau ka ulu ʻana o ke kanaka a i ʻole inā kuhi ʻia kekahi ʻano ʻē aʻe.
- Hiki i ka nui o ka hormone ulu (GH) ke kumu i hoʻonui i nā kumu ulu ulu. I ka poʻe mākua, ua kapa ʻia kēia ʻo ka acromegaly. I nā keiki, kapa ʻia ʻo gigantism.
- Hiki i ka hormone liʻiliʻi ulu ke kumu i ka lohi a i ʻole ka pā o ka ulu ʻana o nā keiki. I nā mākua, hiki i kekahi manawa ke hoʻololi i ka ikehu, ka nui o nā mākala, nā pae kolesterol, a me ka ikaika o ka iwi.
Hoʻohana ʻia paha ka hōʻike GH e nānā i ka pane i ka hoʻomaʻamaʻa acromegaly.
ʻO ka pae maʻamau no ka pae GH he maʻamau:
- No nā kāne makua - 0.4 a 10 nanograms i ka milliliter (ng / mL), a i ʻole 18 a i 44 mau kiʻi kiʻi i kēlā me kēia lita (pmol / L)
- No nā wahine makua - 1 a 14 ng / mL, a i ʻole 44 a 616 pmol / L
- No nā keiki - 10 a 50 ng / mL, a i ʻole 440 a 2200 pmol / L
Hoʻokuʻu ʻia ʻo GH i nā puʻupuʻu. Hoʻololi ka nui a me ka lōʻihi o nā manawa i ka manawa o ka lā, ka makahiki, a me ka moekolohe. ʻO kēia ke kumu e liʻiliʻi iki ai nā ana GH kaulike. ʻO kahi pae kiʻekiʻe ke maʻamau inā huki ʻia ke koko i ka wā o ka lāʻau. Maʻamau paha kahi pae haʻahaʻa inā ua huki ʻia ke koko a puni ka hopena o kahi lāʻau. ʻOi aku ka maikaʻi o ka GH ke ana ʻia ma ke ʻano he ʻāpana o kahi hoʻonāukiuki a i ʻole hoʻāʻo suppression.
Hiki ke loli iki nā pae waiwai maʻamau i waena o nā hale hana ʻokoʻa. Hoʻohana kekahi mau labs i nā ana like ʻole a i ʻole nā hoʻāʻo i nā mea hoʻohālikelike like ʻole. E kamaʻilio i kāu mea hāʻawi e pili ana i ke ʻano o kāu mau hopena hōʻike.
Hōʻike kahi pae kiʻekiʻe o GH:
- Nui loa ka GH i nā mākua, i kapa ʻia ʻo acromegaly. (Hana ʻia kahi hōʻike kūikawā e hōʻoia i kēia kuhi.)
- ʻO ka ulu kūpono ʻole ma muli o ka nui o GH i ka wā kamaliʻi, i kapa ʻia ʻo gigantism. (Hana ʻia kahi hōʻike kūikawā e hōʻoia i kēia kuhi.)
- Kūʻē GH.
- Tumo pituitary.
Hōʻike kahi pae haʻahaʻa o GH:
- ʻO ka ulu lohi i ʻike ʻia i ka wā kamaliʻi a i ʻole wā kamaliʻi, i hoʻokumu ʻia e nā pae haʻahaʻa o GH. (Hana ʻia kahi hōʻike kūikawā e hōʻoia i kēia kuhi.)
- Hypopituitarism (hana haʻahaʻa o ka pituitary gland).
ʻAʻohe pilikia iki i ka lawe ʻia ʻana o kou koko. ʻOkoʻa nā aʻa a me nā aʻa i ka nui mai kekahi kanaka a i kekahi, a mai kekahi ʻaoʻao o ke kino i kekahi ʻē aʻe. ʻOi aku ka paʻakikī o ka loaʻa ʻana o kahi laʻana koko mai kekahi poʻe ma mua o nā poʻe ʻē aʻe.
ʻO nā pilikia ʻē aʻe e pili ana i ke kau ʻana o ke koko he liʻiliʻi, akā hiki ke hoʻopili ʻia:
- Kahe nui ke koko
- Pāleʻale a ʻoluʻolu paha
- Nā punctures he nui e ʻimi i nā uaua
- Hematoma (kūkulu koko ma lalo o ka ʻili)
- Maʻiʻaʻai (i iki kamepiula i kēlā me kēia manawa ka ʻili i haki)
Hōʻike GH
- Hōʻike hoʻonāukiuki ulu ulu - moʻo
ʻO Ali O. Hyperpituitarism, ke kiʻekiʻe kiʻekiʻe, a me nā syndrome hoʻonui. I: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. ʻO Puka Textbook of Pediatrics ʻo Nelson. 21st ed. Piladelapia, PA: Elsevier; 2020: chap 576.
Chernecky CC, Berger BJ. Hone ulu (somatotropin, GH) a me ka hoʻoulu ʻana o ka hōmona (GHRH) - ke koko. I: Chernecky CC, Berger BJ, hua. Nā Hoʻokolohua Laboratory a me nā kaʻina hana Diagnostic. ʻElua huaʻōlelo Piladelapia, PA: Elsevier Saunders; 2013: 599-600.
Cooke DW, Divall SA, Radovick S. Normal a ulu pono ʻole i nā keiki. I: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. ʻO Williams Textbook of Endocrinology. 14th ed. Piladelapia, PA: Elsevier; 2020: chap 25.