ʻIke Insulin C-peptide

ʻO C-peptide kahi mea i hana ʻia ke hana ʻia ka hormone insulin a hoʻokuʻu ʻia i loko o ke kino. Ke ana ka inika C-peptide i ka nui o kēia huahana i ke koko.

Pono kahi laʻana koko.

Aia ka hoʻomākaukau no ka hoʻāʻo ʻana i ke kumu o ke ana ʻana o C-peptide. E noi i kāu mea mālama ola inā ʻaʻole ʻoe e ʻai (wikiwiki) ma mua o ka hōʻoia. E noi paha kāu mea hāʻawi iā ʻoe e haʻalele i ka lawe ʻana i nā lāʻau i hiki ke hoʻololi i nā hopena hōʻike.

Ke hoʻokomo ʻia ke kui kele e huki i ke koko, manaʻo kekahi poʻe i ka ʻeha kaulike. ʻIke wale kekahi i kahi ʻōniʻu a i ʻole kui. Ma hope, loaʻa paha i kahi kūpikipiki a i ʻole ka ʻūlū iki. Hele koke kēia.

Ana ʻia ʻo C-peptide e haʻi i ka ʻokoʻa ma waena o ka insulin a ke kino e hana ai a me ka insulin i hoʻokomo ʻia i loko o ke kino.

ʻO kekahi me ka maʻi diabetes 1 a ʻano 2 paha e ana ʻia i kā lākou pae C-peptide e ʻike ai ke hana mau nei paha ko lākou kino i ka insulin. Ana ʻia hoʻi ʻo C-peptide inā he kō kō ke kō e ʻike ai inā ke hoʻohua nui nei ke kino o ke kanaka iā ia.

Kauoha pinepine ʻia ka hoʻāʻo e nānā i kekahi mau lāʻau i hiki ke kōkua i ke kino e hana i ka nui o ka insulin, e like me ka glucagon-like peptide 1 analogs (GLP-1) a i ʻole DPP IV mea kāohi.

Aia kahi hopena maʻamau ma waena o 0.5 a 2.0 nanograms o ka milliliter (ng / mL), a i ʻole 0.2 a 0.8 nanomoles i kēlā me kēia lita (nmol / L).

Hiki ke loli iki nā pae waiwai maʻamau i waena o nā hale hana ʻokoʻa. Hoʻohana kekahi mau labs i nā ana like ʻole a i ʻole nā ​​hoʻāʻo i nā laʻana like ʻole. E kamaʻilio i kāu mea hāʻawi e pili ana i ke ʻano o kāu mau hopena hōʻike.

Hoʻokumu ʻia ka pae C-peptide maʻamau i ka pae kō kō. ʻO C-peptide kahi hōʻailona e hana ana kou kino i ka insulin. Kuhi kahi pae haʻahaʻa (a ʻaʻohe C-peptide) e hōʻike nei kāu pancreas i kahi liʻiliʻi a ʻaʻohe paha insulin.

• Maʻamau paha kahi pae haʻahaʻa inā ʻaʻole ʻoe i ʻai i kēia manawa. E haʻahaʻa maoli kāu kō kō a me nā kiʻekiʻe o ka insulin ma ia manawa.
• He pae ʻole ka pae haʻahaʻa inā kiʻekiʻe kou kō kō a pono e hana ana kou kino i ka insulin i kēlā manawa.

ʻO ka poʻe me ka maʻi diabetes type 2, momona, a i ʻole ke kūpaʻa ʻana o ka insulin hiki ke loaʻa i kahi pae C-peptide kiʻekiʻe. ʻO kēia ke hana nei ko lākou kino i ka nui o ka insulin e mālama (a i ʻole hoʻāʻo e mālama) i ko lākou kō kō i maʻamau.

Aia kahi pilikia iki i ka lawe ʻia ʻana o kou koko. Hoʻohālikelike nā aʻa a me nā aʻa i ka nui mai kekahi kanaka a i kekahi ʻē aʻe a mai kekahi ʻaoʻao o ke kino i kekahi. ʻOi aku ka paʻakikī o ka loaʻa ʻana o kahi laʻana koko mai kekahi poʻe ma mua o nā poʻe ʻē aʻe.

ʻO nā pilikia ʻē aʻe e pili ana i ke kau ʻana o ke koko he liʻiliʻi akā hiki ke hoʻopili ʻia:

• Kahena
• Pāleʻale a ʻoluʻolu paha
• Nā punctures he nui e hoʻāʻo e ʻimi i nā veins
• Hematoma (kūkulu koko ma lalo o ka ʻili)
• Maʻiʻaʻai (i iki kamepiula i kēlā me kēia manawa ka ʻili i haki)

C-peptide

• Hōʻaʻo koko

Atkinson MA, Mcgill DE, Dassau E, Laffel L. ʻAno 1 diabetes mellitus. I: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. ʻO Williams Textbook of Endocrinology. 14th ed. Piladelapia, PA: Elsevier; 2020: chap 36.

Chernecky CC, Berger BJ. C-peptide (hoʻohui peptide) - serum. I: Chernecky CC, Berger BJ, hua. Nā Hoʻokolohua Laboratory a me nā kaʻina hana Diagnostic. ʻElua huaʻōlelo Piladelapia, PA: Elsevier; 2013: 391-392.

Kahn CR, Ferris HA, O'Neill BT. Pathophysiology o ka type 2 diabetes mellitus. I: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. ʻO Williams Textbook of Endocrinology. 14th ed. Piladelapia, PA: Elsevier; 2020: chap 34.

ʻO Pearson ER, ʻo McCrimmon RJ. Diabetes mellitus. I: Ralston SH, Penman ID, Strachen MWJ, Hobson RP, eds. Nā Kumuhana a Davidson a me ka hana o ka lāʻau. 23rd Ed. Piladelapia, PA: Elsevier; 2020: chap 20.