ʻO ka hoʻāʻo Glucose-6-phosphate dehydrogenase

ʻO Glucose-6-phosphate dehydrogenase (G6PD) kahi protein e kōkua pono i nā hunaola ʻulaʻula e hana pono. Nānā ka hōʻike G6PD i ka nui (ka hana) o kēia mea i nā ʻulaʻula koko.

Pono kahi laʻana koko.

ʻAʻole pono ka hoʻomākaukau kūikawā.

Ke hoʻokomo ʻia ke kui kele e huki i ke koko, manaʻo kekahi poʻe i ka ʻeha kaulike. ʻIke wale kekahi i kahi ʻōniʻu a i ʻole kui. Ma hope, loaʻa paha i kahi kūpikipiki a i ʻole ka ʻūlū iki. Hele koke kēia.

Hiki i kāu kauka olakino ke koi i kēia hōʻoia inā loaʻa iā ʻoe nā hōʻailona o ka hemahema G6PD. ʻO kēia ʻaʻole lawa kāu hana G6PD.

ʻOi aku ka liʻiliʻi o ka hana G6PD i ka luku ʻia ʻana o nā hunaola ʻulaʻula. Kapa ʻia kēia hana he hemolysis. Ke hana ʻiʻo kēia hana, ua kapa ʻia ia he hanana hemolytic.

Hiki ke hoʻomaka ʻia nā hanana hemolytic e nā maʻi, kekahi mau meaʻai (e like me nā pī fava), a me kekahi mau lāʻau, e like me:

• Nā lāʻau i hoʻohana e hōʻemi i ke kuni
• Nitrofurantoin
• Phenacetin
• Primaquine
• Sulfonamides
• ʻO Thiazide diuretics
• Tolbutamide
• Quinidine

Hoʻololi nā waiwai maʻamau a pili i ka hale hana i hoʻohana ʻia. Hoʻohana kekahi mau labs i nā ana like ʻole a i ʻole nā ​​hoʻāʻo i nā laʻana like ʻole. E kamaʻilio i kāu mea hāʻawi e pili ana i ke ʻano o kāu mau hopena hōʻike.

Nā hualoaʻa kūpono ʻole i loaʻa iā ʻoe kahi hemahema G6PD. Hiki i kēia ke kumu i ka hemolytic anemia i kekahi mau ʻano.

ʻAʻohe pilikia iki i ka lawe ʻia ʻana o kou koko. ʻOkoʻa nā aʻa a me nā aʻa i ka nui mai kekahi kanaka a i kekahi ʻē aʻe a mai kekahi ʻaoʻao o ke kino i kekahi. ʻOi aku ka paʻakikī o ka loaʻa ʻana o kahi laʻana koko mai kekahi poʻe ma mua o nā poʻe ʻē aʻe.

ʻO nā pilikia ʻē aʻe e pili ana i ke kau ʻana o ke koko he liʻiliʻi, akā hiki ke hoʻopili ʻia:

• Kahe nui ke koko
• Pāleʻale a ʻoluʻolu paha
• Nā punctures he nui e ʻimi i nā uaua
• Hematoma (kūkulu koko ma lalo o ka ʻili)
• Maʻiʻaʻai (i iki kamepiula i kēlā me kēia manawa ka ʻili i haki)

Hōʻike RBC G6PD; Pale G6PD

Chernecky CC, Berger BJ. ʻO Glucose-6-phosphate dehydrogenase (G6PD, G-6-PD), nui - koko. I: Chernecky CC, Berger BJ, hua. Nā Hoʻokolohua Laboratory a me nā kaʻina hana Diagnostic. ʻElua huaʻōlelo St Louis, MO: Elsevier Saunders; 2013: 594-595.

ʻO Gallagher PG. Hemolytic anemias: ʻulaʻula koko membrane a me nā kīnā metabolik. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil. 26th ed. Piladelapia, PA: Elsevier; 2020: chap152.