Mea Kākau: William Ramirez
Lā O Ka Hana: 22 Kepakemapa 2021
HōʻAno Hou I Ka Lā: 13 Nowemapa 2024
Anonim
Hōʻike hoʻonāukiuki ACTH - Kino PaʻA
Hōʻike hoʻonāukiuki ACTH - Kino PaʻA

Hoʻomaʻama ka hōʻike hoʻonāukiuki ACTH i ke ʻano o ka pane ʻana o ka momona adrenal i ka adrenocorticotropic hormone (ACTH). ʻO ka ACTH kahi hone i hana ʻia i loko o ka pituitary gland e hoʻoulu i nā adrenal glands e hoʻokuʻu i kahi hōmona i kapa ʻia ʻo cortisol.

Hana ʻia ka hōʻoia ma ke ala aʻe:

  • Kuhi ʻia kou koko.
  • Loaʻa iā ʻoe kahi kī (injection) o ACTH, maʻa mau i ka mākala i kou poʻohiwi. He hana mana (synthetic) kā ka ACTH.
  • Ma hope o 30 mau minuke a i ʻole 60 mau minuke, a i ʻole ʻelua, e like me ka nui o ka ACTH i loaʻa iā ʻoe, huki hou ʻia kou koko.
  • Nānā ke keʻena hoʻokolohua i ka pae cortisol i nā laʻana koko.

Loaʻa paha iā ʻoe nā hoʻokolohua koko ʻē aʻe, e laʻa me ACTH, ma ke ʻāpana o ka hoʻokolohua koko mua. Me nā hoʻokolohua koko, loaʻa paha iā ʻoe kahi hōʻike mimi Cortisol a i ʻole ka mimi 17-ketosteroids test, kahi e hoʻopili ai i ka mimi ma kahi o 24 mau hola.

Pono paha ʻoe e kaupalena i nā hana a ʻai i nā meaʻai i kiʻekiʻe i nā hāpikipiki 12 a 24 mau hola ma mua o ka hoʻāʻo. E noi paha ʻoe e hoʻokē ʻai no 6 mau hola ma mua o ka hoʻāʻo. I kekahi manawa, ʻaʻole pono kahi hoʻomākaukau kūikawā. E noi ʻia paha ʻoe e haʻalele no ka lawe manawa ʻana i nā lāʻau, e like me ka hydrocortisone, i hiki ke hoʻopilikia i ka hoʻāʻo ʻana o ke koko.


Ke hoʻokomo ʻia ke kui kele e huki i ke koko, manaʻo kekahi poʻe i ka ʻeha kaulike. ʻIke wale kekahi i kahi ʻōniʻu a i ʻole kui. Ma hope, loaʻa paha i kahi kūpikipiki a i ʻole ʻeha iki. Hele koke kēia.

ʻO ke kuʻi ʻana i ka poʻohiwi ke kumu i ka ʻehaʻeha a ʻeha paha.

Hoʻomaopopo kekahi poʻe i ka pīpī, ka makaʻu, a me ka nausea paha ma hope o ka hoʻokomo ʻia o ACTH

Hiki i kēia hōʻoia ke kōkua i ka hoʻoholo inā he maʻamau kāu adrenal a me nā pituitary glands. Hoʻohana pinepine ʻia ia ke manaʻo kāu kauka olakino loaʻa iā ʻoe kahi pilikia glandula adrenal, e like me ka maʻi Addison a i ʻole ka lawa ʻole o ka pituitary. Hoʻohana pū ʻia ia e ʻike inā ua hoʻōla kāu pituitary a me nā adrenal glands mai ka hoʻolōʻihi ʻia ʻana o nā lāʻau glucocorticoid, e like me prednisone.

Hoʻohui ʻia kahi hoʻonui i ka cortisol ma hope o ka hoʻonāukiuki ʻana e ACTH. ʻOi aku ka kiʻekiʻe o Cortisol ma hope o ka hoʻonāuki ʻana o ACTH ma mua o 18 a 20 mcg / dL a i ʻole 497 a 552 nmol / L, e like me ka hopena o ka ACTH i hoʻohana ai.

Hiki ke loli iki nā pae waiwai maʻamau i waena o nā hale hana ʻokoʻa. Hoʻohana kekahi mau labs i nā ana like ʻole a i ʻole hoʻokolohua i nā hoʻohālikelike like ʻole. E kamaʻilio i kāu mea hāʻawi e pili ana i ke ʻano o kāu mau hopena hōʻike.


Kōkua kēia hōʻike i ka ʻike inā loaʻa iā ʻoe:

  • ʻO ka pilikia adrenal koʻikoʻi (ke ʻano hoʻoweliweli e ola nei inā ʻaʻole lawa ka cortisol)
  • Addison maʻi (adrenal glands e ole paka lawa cortisol)
  • Hypopituitarism (ʻaʻole loaʻa i nā pituitary gland ka lawa ʻana o nā hormoni e like me ACTH)

ʻAʻohe pilikia iki i ka lawe ʻia ʻana o kou koko. ʻOkoʻa nā aʻa a me nā aʻa i ka nui mai kekahi kanaka a i kekahi, a mai kekahi ʻaoʻao o ke kino i kekahi ʻē aʻe. ʻOi aku ka paʻakikī o ka lawe ʻana i ke koko mai kekahi poʻe ma mua o nā poʻe ʻē aʻe.

ʻO nā pilikia ʻē aʻe e pili ana i ke kau ʻana o ke koko he liʻiliʻi, akā hiki ke hoʻopili ʻia:

  • Kahe nui ke koko
  • Pāleʻale a ʻoluʻolu paha
  • Nā punctures he nui e ʻimi i nā uaua
  • Hematoma (hōʻiliʻili koko ma lalo o ka ʻili)
  • Maʻiʻaʻai (i iki kamepiula i kēlā me kēia manawa ka ʻili i haki)

Hōʻike o ka adrenal Reserve; Hōʻoia hoʻonāukiuki Cosyntropin; Hōʻike hoʻāla Cortrosyn; Hōʻike hoʻonāukiuki Synacthen; Hōʻike hoʻonāukiuki ʻo Tetracosactide


ʻO Barthel A, Willenberg HS, Gruber M, Bornstein SR. Ka lawa ʻole o adrenal. I: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Makua a Pediatric. ʻEpekema 7 Piladelapia, PA: Elsevier Saunders; 2016: chap 102.

Chernecky CC, Berger BJ. Hōʻike hoʻonāukiuki ACTH - diagnostic. I: Chernecky CC, Berger BJ, hua. Nā Hoʻokolohua Laboratory a me nā kaʻina hana Diagnostic. ʻElua huaʻōlelo St Louis, MO: Elsevier Saunders; 2013: 98.

ʻO Stewart PM, Newell-Kumukūʻai JDC. ʻO ka Cortex adrenal. I: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. ʻO Williams Textbook of Endocrinology. 13th ed. Piladelapia, PA: Elsevier; 2016: chap 15.

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