Hōʻike hemolysis kō-wai

ʻO ka hoʻokolohua hemolysis kō-wai he hōʻike koko e ʻike i nā hunaola ʻulaʻula palupalu. Hana ia i kēia me ka hoʻāʻo ʻana pehea e kū pono ai lākou i ka puhū ʻana i kahi kō.

Pono kahi laʻana koko.

ʻAʻole pono kahi hoʻomākaukau kūikawā no kēia hōʻike.

Ke hoʻokomo ʻia ke kui kele e huki i ke koko, manaʻo kekahi poʻe i ka ʻeha kaulike. ʻIke wale kekahi i kahi ʻōniʻu a i ʻole kui. Ma hope, loaʻa paha i kahi kūpikipiki a i ʻole ka ʻūlū iki. Hele koke kēia.

Hiki i kāu kauka olakino ke koi i kēia hōʻike inā loaʻa iā ʻoe nā hōʻailona a i ʻole nā ​​ʻōuli o paroxysmal nocturnal hemoglobinuria (PNH) a i ʻole hemolytic anemia o ke kumu i ʻike ʻole ʻia. Hemolytic anemia kahi ʻano e make ai nā hunaola ʻulaʻula ma mua o ka pono. ʻO ka PNH ke koko ʻulaʻula e hōʻeha loa ʻia e ka ʻōnaehana kōkua o ke kino. ʻO ka ʻōnaehana hoʻopiha nā protein e neʻe i ke kahe o ke koko. Hana pū kēia mau protein me ka ʻōnaehana pale.

Kapa ʻia kahi hopena hōʻike maʻamau he hopena maikaʻi ʻole. Hōʻike kahi hopena maʻamau ma lalo o 5% o nā hunaola ʻulaʻula e haki ke hōʻoia ʻia. Kapa ʻia kēia haʻihaʻi he hemolysis.

ʻAʻole hoʻokau ʻia kahi hōʻike maikaʻi ʻole i PNH. Hiki ke hopena i nā hopena maikaʻi ʻole inā loaʻa ʻole i ka ʻāpana wai o ke koko (serum) ka mea kōkua.

Hiki ke loli iki nā pae waiwai maʻamau i waena o nā hale hana ʻokoʻa. Hoʻohana kekahi mau labs i nā ana like ʻole a i ʻole nā ​​hoʻāʻo i nā laʻana like ʻole. E kamaʻilio i kāu mea hāʻawi e pili ana i ke ʻano o kāu mau hopena hōʻike.

ʻO ka hopena o ka hopena hōʻoia maikaʻi ʻole nā ​​hopena. I kahi hōʻoia maikaʻi, ʻoi aku ma mua o 10% o nā hunaola ʻulaʻula e haki. Hōʻike ia i ka PNH o ke kanaka.

Hiki i kekahi mau kūlana ke hoʻohālikelike i nā hopena hōʻike (i kapa ʻia ʻo "positive positive"). ʻO kēia mau ʻano nā anemias hemolytic autoimmune a me leukemia.

ʻAʻohe pilikia iki i ka lawe ʻia ʻana o kou koko. ʻOkoʻa nā aʻa a me nā aʻa i ka nui mai kekahi kanaka a i kekahi ʻē aʻe a mai kekahi ʻaoʻao o ke kino i kekahi. ʻOi aku ka paʻakikī o ka lawe ʻana i ke koko mai kekahi poʻe ma mua o nā poʻe ʻē aʻe.

ʻO nā pilikia ʻē aʻe e pili ana i ke kau ʻana o ke koko he liʻiliʻi, akā hiki ke hoʻopili ʻia:

• Kahe nui ke koko
• Pāleʻale a ʻoluʻolu paha
• Nā punctures he nui e ʻimi i nā uaua
• Hematoma (kūkulu koko ma lalo o ka ʻili)
• Maʻiʻaʻai (i iki kamepiula i kēlā me kēia manawa ka ʻili i haki)

Hōʻike hemolisis Sucrose; Hemolytic anemia kō wai hemolysis hōʻike; Paroxysmal nocturnal hemoglobinuria kō wai hemolysis hōʻike; Hōʻike hemolysis wai kō PNH kō

ʻO Brodsky RA. ʻO Paroxysmal hemoglobinuria nocturnal. I: Hoffman R, Benz EJ, Silberstein LE, eds. Hematology: Nā Kumumanaʻo a me ka Hoʻomeheu. ʻEpekema 7 Piladelapia, PA: Elsevier; 2018: chap 31.

Chernecky CC, Berger BJ. Hōʻike hemolisis Sucrose - diagnostic. I: Chernecky CC, Berger BJ, hua. Nā Hoʻokolohua Laboratory a me nā kaʻina hana Diagnostic. ʻElua huaʻōlelo St Louis, MO: Elsevier Saunders; 2013: 1050.

ʻO Gallagher PG. Hemolytic anemias: ʻulaʻula koko membrane a me nā kīnā metabolik. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil. 26th ed. Piladelapia, PA: Elsevier; 2020: chap152.