Hōʻike koko Methylmalonic acid

Ke ana ʻia ka methylmalonic acid koko i ka nui o ka methylmalonic acid i ke koko.

Pono kahi laʻana koko.

ʻAʻole pono kahi hoʻomākaukau kūikawā.

Ke hoʻokomo ʻia ke kui kele e huki i ke koko, manaʻo kekahi poʻe i ka ʻeha kaulike. ʻIke wale kekahi i kahi ʻōniʻu a i ʻole kui. Ma hope, loaʻa paha i kahi kuʻi a i ʻole ʻeha iki. Hele koke kēia.

ʻO ka Methylmalonic acid kahi mea i hana ʻia ke hana ʻia nā protein, i kapa ʻia nā amino acid, i loko o ke kino e haki.

E kauoha paha ka mea mālama ola i kēia hoʻokolohua inā loaʻa nā hōʻailona o kekahi mau ʻano maʻi, e like me ka methylmalonic acidemia. ʻO ka hoʻāʻo ʻana no kēia maʻi e hana pinepine ʻia ma ke ʻano he ʻāpana o kahi hōʻike loiloi hānau hou.

E hana pū ʻia paha kēia hōʻike me nā hōʻike ʻē aʻe e nānā ai no ka hemahema o ka wikamina B12.

ʻO nā waiwai maʻamau he 0.07 a 0.27 micromoles i kēlā me kēia lita.

Hiki ke loli iki nā pae waiwai maʻamau i waena o nā hale hana ʻokoʻa. Hoʻohana kekahi mau labs i nā ana like ʻole a i ʻole nā ​​hoʻāʻo i nā laʻana like ʻole. E kamaʻilio me kāu kauka e pili ana i ke ʻano o kāu mau hopena hōʻike kikoʻī.

ʻO kahi kiʻekiʻe ma mua o ke kumukūʻai maʻamau ma muli o ka hemahema o ka wikamina B12 a i ʻole ka methylmalonic acidemia.

ʻAʻohe pilikia iki i ka lawe ʻia ʻana o kou koko. ʻOkoʻa nā aʻa a me nā aʻa i ka nui mai kekahi kanaka a i kekahi ʻē aʻe a mai kekahi ʻaoʻao o ke kino i kekahi. ʻOi aku ka paʻakikī o ka lawe ʻana i ke koko mai kekahi poʻe ma mua o nā poʻe ʻē aʻe.

ʻO nā pilikia ʻē aʻe e pili ana i ke kau ʻana o ke koko he liʻiliʻi, akā hiki ke hoʻopili ʻia:

• Pāleʻale a ʻoluʻolu paha
• Nā punctures he nui e ʻimi i nā uaua
• Hematoma (kūkulu koko ma lalo o ka ʻili)
• Kahe nui ke koko
• Maʻiʻaʻai (i iki kamepiula i kēlā me kēia manawa ka ʻili i haki)

• Hōʻaʻo koko

ʻO Antony AC. Nā anemias Megaloblastic. I: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Nā Kumumanaʻo a me ka Hoʻomeheu. ʻEpekema 7 Piladelapia, PA: Elsevier; 2018: chap 39.

ʻO Elghetany MT, Schexneider KI, Banki K. Nā maʻi Erythrocytic. I: McPherson RA, Pincus MR, hua. ʻO kā Henry's Clinical Diagnosis a me Management e nā Laboratory Methods. 23rd Ed. St Louis, MO: Elsevier; 2017: chap 32.