Hōʻike koko isoenzyme LDH

ʻO ka hoʻāʻo ʻana o ka lactate dehydrogenase (LDH) isoenzyme hōʻoia i ka nui o nā ʻano ʻokoʻa o ka LDH i loko o ke koko.

Pono kahi laʻana koko.

E haʻi aku paha ka mea mālama ola iā ʻoe e haʻalele iki i ka lawe ʻana i kekahi lāʻau i mua o ka hoʻāʻo ʻana.

Nā lāʻau i hiki ke hoʻonui i nā ana LDH:

• Nā Anesthetics
• ʻAspirin
• Colchisin
• Clofibrate
• ʻO Cocaine
• Fluorides
• Mithramycin
• Nā Narcotics
• Procainamide
• Statins
• Steroids (glucocorticoids)

Mai hōʻoki i ka lawe ʻana i kekahi lāʻau i mua o ke kamaʻilio ʻana i kāu mea hāʻawi.

Ke hoʻokomo ʻia ke kui kele e huki i ke koko, manaʻo kekahi poʻe i ka ʻeha iki. ʻIke wale kekahi i kahi ʻōniʻu a i ʻole kui. Ma hope, loaʻa paha i kahi kūpikipiki a i ʻole ka ʻūlū iki. Hele koke kēia.

ʻO ka LDH kahi enzyme i loaʻa i nā kino o ke kino e like me ka puʻuwai, ka ate, ka puʻuwai, ka ʻiwi iwi, ka lolo, nā aʻa koko, a me nā akemāmā. Ke hōʻino ʻia nā kino o ke kino, hoʻokuʻu ʻia ʻo LDH i loko o ke koko.

Kōkua ka hoʻāʻo LDH i ka wahi o ka hōʻino kino.

Aia ʻo LDH i ʻelima mau ʻano, i ʻokoʻa iki i ka hanana.

• ʻIke ʻia ʻo LDH-1 i ka mākala puʻuwai a me nā hunaola ʻulaʻula.
• Mālama ʻia ʻo LDH-2 i nā hunaola keokeo.
• ʻO LDH-3 ka mea kiʻekiʻe loa ma ka māmā.
• ʻO ka LDH-4 ka mea kiʻekiʻe loa ma ka puʻupaʻa, placenta, a me pancreas.
• ʻO ka LDH-5 kiʻekiʻe loa i ke akepaʻa a me nā mākala iwi.

Hiki ke ana ʻia kēia mau mea āpau i ke koko.

Hiki i nā pae LDH kiʻekiʻe ma mua o ka maʻamau ke ʻōlelo:

• Hemolytic anemia
• Hypotension
• Mononucleosis maʻi maʻi
• Intestinal ischemia (ka nele o ke koko) a me ka infarction (ka make ʻana o nā aʻa)
• ʻO ka cardiomyopathy Ischemic
• ʻO ka maʻi akepaʻa e like me ka hepatitis
• Ka make ʻana o ka naʻau
• ʻEha ʻeha
• Hoʻoiho muscular
• ʻO Pancreatitis
• Ka make ʻana o ka naʻau
• Hahau

ʻAʻohe liʻiliʻi o ka lawe ʻia ʻana o kou koko. ʻOkoʻa nā aʻa a me nā aʻa i ka nui mai kekahi kanaka a i kekahi ʻē aʻe a mai kekahi ʻaoʻao o ke kino i kekahi. ʻOi aku ka paʻakikī o ka lawe ʻana i ke koko mai kekahi poʻe ma mua o nā poʻe ʻē aʻe.

ʻO nā pilikia ʻē aʻe e pili ana i ke kau ʻana o ke koko he liʻiliʻi akā hiki ke hoʻopili ʻia:

• Kahe nui ke koko
• Pāleʻale a ʻoluʻolu paha
• Nā punctures he nui e ʻimi i nā uaua
• Hematoma (hōʻiliʻili koko ma lalo o ka ʻili)
• Maʻiʻaʻai (i iki kamepiula i kēlā me kēia manawa ka ʻili i haki)

LD; LDH; Lactic (lactate) dehydrogenase isoenzymes

• Hōʻaʻo koko

Carty RP, Pincus MR, Sarafraz-Yazdi E. ʻO ka enzymology lapaʻau. I: McPherson RA, Pincus MR, hua. ʻO kā Henry's Clinical Diagnosis a me Management e nā Laboratory Methods. 23rd Ed. St Louis, MO: Elsevier; 2017: chap 20.

Chernecky CC, Berger BJ. Lenoate dehydrogenase (LD) isoenzymes. I: Chernecky CC, Berger BJ, hua. Nā Hoʻokolohua Laboratory a me nā kaʻina hana Diagnostic. ʻElua huaʻōlelo St Louis, MO: Elsevier Saunders; 2013: 702-703.