Hoʻāʻo lactate dehydrogenase
ʻO Lactate dehydrogenase (LDH) kahi protein e kōkua i ka hana ʻana i ka ikehu i loko o ke kino. Kuhi kahi hōʻike LDH i ka nui o ka LDH i loko o ke koko.
Pono kahi laʻana koko.
ʻAʻole pono kahi hoʻomākaukau kikoʻī.
Ke hoʻokomo ʻia ke kui kele e huki i ke koko, manaʻo kekahi poʻe i ka ʻeha kaulike. ʻIke wale kekahi i kahi ʻōniʻu a i ʻole kui. Ma hope, loaʻa paha i kahi kūpikipiki a i ʻole ka ʻūlū iki. Hele koke kēia.
Ana pinepine ʻia ʻo LDH e nānā no ka hōʻino ʻana o ka iʻa. Aia ʻo LDH i loko o nā kino he nui, keu hoʻi ka puʻuwai, ka ate, ka puʻupaʻa, nā mākala, ka lolo, nā aʻa koko, a me nā akemāmā.
Nā kūlana ʻē aʻe e hana ʻia ai ka hōʻike me:
- Helu koko ʻulaʻula haahaa (anemia)
- Ka maʻi ʻaʻai, me ka maʻi ʻaʻai koko (leukemia) a i ʻole ka maʻi ʻaʻai lymph (lymphoma)
105 a 333 mau pae honua no ka lita (IU / L).
Hiki ke loli iki nā pae waiwai maʻamau i waena o nā hale hana ʻokoʻa. Hoʻohana kekahi mau labs i nā ana like ʻole a i ʻole nā hoʻāʻo i nā laʻana like ʻole. E kamaʻilio i kāu mea hāʻawi e pili ana i ke ʻano o kāu mau hopena kikoʻī.
E hōʻike paha kahi pae kiʻekiʻe aʻe ma mua o ka maʻamau:
- Kahe o ke kahe o ke kahe (ischemia)
- Maʻi hohola
- Hemolytic anemia
- Mononucleosis maʻi maʻi
- Leukemia a i ʻole lymphoma
- ʻO ka maʻi ate (ʻo kahi laʻana, hepatitis)
- Kaomi haʻahaʻa
- ʻEha ʻeha
- ʻO ka nāwaliwali o ka mākala a me ka nalo ʻana o kaʻiʻo muscle (mustrular dystrophy)
- ʻO ka hoʻokumu hou ʻana o nā ʻaʻa ʻē aʻe (maʻamau ka maʻi ʻaʻai)
- ʻO Pancreatitis
- Hahau
- Ka make kuʻi
Inā kiʻekiʻe kou pae LDH, hiki i kāu mea hāʻawi ke paipai iā LDH isoenzymes hōʻoia e hoʻoholo i kahi o nā hōʻino kino.
ʻAʻohe pilikia iki i ka lawe ʻia ʻana o kou koko. ʻOkoʻa nā aʻa a me nā aʻa i ka nui mai kekahi kanaka a i kekahi ʻē aʻe a mai kekahi ʻaoʻao o ke kino i kekahi. ʻOi aku ka paʻakikī o ka lawe ʻana i ke koko mai kekahi poʻe ma mua o nā poʻe ʻē aʻe.
ʻO nā pilikia ʻē aʻe e pili ana i ke kau ʻana o ke koko he liʻiliʻi, akā hiki ke hoʻopili ʻia:
- Kahe nui ke koko
- Pāleʻale a ʻoluʻolu paha
- Nā punctures he nui e ʻimi i nā uaua
- Hematoma (kūkulu koko ma lalo o ka ʻili)
- Maʻiʻaʻai (i iki kamepiula i kēlā me kēia manawa ka ʻili i haki)
Hoʻāʻo LDH; ʻO ka hoʻāʻo ʻana ʻo Lactic acid dehydrogenase
Carty RP, Pincus MR, Sarafraz-Yazdi E. ʻO ka enzymology lapaʻau. I: McPherson RA, Pincus MR, hua. ʻO kā Henry's Clinical Diagnosis a me Management e nā Laboratory Methods. 23rd Ed. St Louis, MO: Elsevier; 2017: chap 20.
Chernecky CC, Berger BJ. Lactate dehydrogenase. I: Chernecky CC, Berger BJ, hua. Nā Hoʻokolohua Laboratory a me nā kaʻina hana Diagnostic. ʻElua huaʻōlelo St Louis, MO: Elsevier Saunders; 2013: 701-702.