Pūmua C-reactive

Hana ʻia ka protein C-reactive (CRP) e ke ake. Piʻi ka pae o CRP ke loaʻa ka mumū ma loko o ke kino. ʻO ia kekahi o kahi hui o nā protein i kapa ʻia he reactant phase reactants e piʻi i pane i ka lī. Hoʻonui nā pae o nā reactant phase huehue i ka pane ʻana i kekahi mau proteins inflammatory i kapa ʻia he cytokines. Hana ʻia kēia mau protein e nā hunaola keokeo i ka wā o ka mumū.

Kūkākūkā kēia ʻatikala i ka hoʻokolohua koko i hana ʻia e ana i ka nui o CRP i kou koko.

Pono kahi laʻana koko. Lawe pinepine ʻia kēia mai kahi aa. Kapa ʻia ke kaʻina hana he venipuncture.

ʻAʻole pono nā kapuaʻi kūikawā e hoʻomākaukau ai no kēia hōʻike.

Ke hoʻokomo ʻia ke kui kele e huki i ke koko, manaʻo kekahi poʻe i ka ʻeha kaulike. ʻO ka manaʻo ʻē aʻe wale nō he prick a i ʻole sensation stinging paha. Ma hope, aia paha kekahi ʻōkā.

ʻO ka hōʻike CRP kahi hōʻike ākea e nānā ai no ka mumū i ke kino. ʻAʻole ia he hōʻike kikoʻī. Hiki iā ia ke hōʻike he maʻi kou ma kahi ma kou kino, akā ʻaʻole hiki ke kuhikuhi i kahi kikoʻī. Hana pinepine ʻia ka hōʻike CRP me ka ESR a i ʻole ka hoʻēmi helu sedimentation i nānā pū ʻia no ka pehu.

Loaʻa paha iā ʻoe kēia hōʻike i:

• E hōʻoia no ka hoʻoulu ʻana i nā maʻi ʻino e like me rheumatoid arthritis, lupus, a i ʻole vasculitis.
• E hoʻoholo inā hana ka lāʻau anti-inflammatory e mālama i kahi maʻi a i ʻole ke ʻano.

Eia nō naʻe, ʻaʻole ka manaʻo o kahi pae CRP haʻahaʻa haʻahaʻa i ka loaʻa ʻole o ka mumū i kēia manawa. ʻAʻole hiki ke hoʻonui ʻia nā pae o CRP i ka poʻe me ka rheumatoid arthritis a me ka lupus. ʻAʻole ʻike ʻia ke kumu o kēia.

ʻO kahi ho'āʻo CRP maʻalahi hou aʻe, i kapa ʻia he hoʻāʻo C-reactive protein (hs-CRP) hoʻoweliweli kiʻekiʻe, i loaʻa e hoʻoholo i ka pilikia o ke kanaka no ka maʻi puʻuwai.

Hoʻololi nā helu CRP maʻamau mai nā lab a lab. ʻO ka maʻamau, aia nā pae haʻahaʻa o CRP i ʻike ʻia i ke koko. Hoʻonui iki nā pae me ka makahiki, ka wahine wahine a me ʻAmelika ʻAmelika.

ʻO ka CRP serum i hoʻonui ʻia e pili ana i nā kumumea kūlohelohe o ka maʻi maʻi a hiki ke hōʻike i ke kuleana o kēia mau pilikia i ka hopena o ka mumū.

Wahi a ka American Heart Association, nā hopena o ka hs-CRP i ka hoʻoholo ʻana i ka pilikia no ka maʻi puʻuwai e hiki ke unuhi ʻia penei:

• Aia ʻoe i ka makaʻu haʻahaʻa i ka hoʻomohala ʻana i nā maʻi maʻi maʻi inā ʻoi aku ka haʻahaʻa o kāu pae hs-CRP ma mua o 1.0 mg / L.
• Aia ʻoe ma ka awelika o ka makaʻu ʻana i ka maʻi maʻi ʻōpū inā aia kou mau pae ma waena o 1.0 mg / L a me 3.0 mg / L.
• Nui kou makaʻu no ka maʻi maʻi maʻi inā ʻoi aku ka kiʻekiʻe o kāu pae hs-CRP ma mua o 3.0 mg / L.

Kaha: hiki ke loli iki i nā pae waiwai maʻamau ma waena o nā hale hana ʻokoʻa. E kamaʻilio me kāu mea mālama ola e pili ana i ke ʻano o kāu mau hopena hōʻike kikoʻī.

Hōʻike nā hiʻohiʻona ma luna i nā ana maʻamau no nā hopena no kēia mau hoʻāʻo. Hoʻohana kekahi mau keʻena hoʻokolohua i nā ana like ʻole a i ʻole hoʻokolohua i nā hoʻohālikelike like ʻole.

ʻO kahi hōʻoia maikaʻi he maʻi kou i ke kino. Pili paha kēia i nā ʻano ʻano like ʻole, me:

• Kanesa
• Maʻi maʻi hoʻopili
• Maʻi hohola
• Maʻi kīnā
• ʻO ka maʻi maʻi ʻōpū (IBD)
• Lupus
• Pulumonia
• Rheumatoid arthritis
• Mū Rumatika
• Maʻi puʻu

ʻAʻole pili kēia papa inoa.

Kahakaha: Loaʻa nā hopena CRP maikaʻi i ka hapa hope o ka hāpai ʻana a i ʻole me ka hoʻohana ʻana o nā lāʻau kaohi hānau (oral contraceptives).

ʻO nā pōpilikia e pili ana i ke kahe ʻana o ke koko he liʻiliʻi, akā hiki ke hoʻopili ʻia:

• Kahe nui ke koko
• Pāleʻale a ʻoluʻolu paha
• Hematoma (hōʻiliʻili koko ma lalo o ka ʻili)
• Maʻiʻaʻai (i iki kamepiula i kēlā me kēia manawa ka ʻili i haki)

CRP; ʻO ke kinona C-reactive protein kiʻekiʻe; hs-CRP

• Hōʻaʻo koko

Chernecky CC, Berger BJ. C. I: Chernecky CC, Berger BJ, hua. Nā Hoʻokolohua Laboratory a me nā kaʻina hana Diagnostic. ʻElua huaʻōlelo St Louis, MO: Elsevier Saunders; 2013: 266-432.

ʻO Dietzen DJ. ʻO nā amino acid, peptides, a me nā protein. I: Rifai N, ed. ʻO Tietz Textbook of Clinical Chemistry a me nā Molecular Diagnostics. ʻElua huaʻōlelo St Louis, MO: Elsevier; 2018: chap 28.

ʻO Ridker PM, Libby P, Buring JE. ʻO nā māka hōʻailona a me ka pale mua ʻana i ka maʻi maʻi maʻi maʻi. I: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, eds. ʻO ka maʻi puʻuwai ʻo Braunwald: He puke aʻo no ka lāʻau Cardiovascular. 11th hua. Piladelapia, PA: Elsevier; 2019: chap 45.