Carcinoma Adrenocortical

He maʻi ʻaʻai ʻo Adrenocortical carcinoma (ACC) o nā ʻōpū adrenal. ʻO nā glands adrenal ʻelua mau gland triangle-shaped. Aia kekahi gland ma luna o kēlā me kēia puʻupaʻa.

ʻO ACC ka mea maʻamau i nā keiki ma mua o 5 mau makahiki a me nā mākua i ko lākou 40s a me 50s.

Pili paha ke ʻano i kahi maʻi maʻi ʻaʻai i hoʻoili ʻia e nā ʻohana (hoʻoilina). Hiki i nā kāne a me nā wahine ke hoʻomohala i kēia tumo.

Hiki i ka ACC ke hana i nā hormones cortisol, aldosterone, estrogen, a i ʻole testosterone, a me nā hormones ʻē aʻe. I nā wahine hoʻokuʻu pinepine ka tumo i kēia mau homona, i hiki ke alakaʻi i nā ʻano kāne.

Kākaʻikahi loa ʻo ACC. ʻAʻole ʻike ʻia ke kumu.

ʻO nā ʻōuli o ka hoʻonui ʻia o ka cortisol a i ʻole nā ​​homone adrenal gland e komo pū paha:

• Fatty, poepoe kiʻekiʻe ma ke kua ma lalo pono o ka ʻāʻī (puʻupuʻu buffalo)
• ʻO ka helehelena ākea, a me nā helehelena poʻi me nā papalina pudgy (maka mahina)
• Ka momona
• Ka ulu ulu ʻana (ke kino pōkole)
• Virilization - ke ʻano o nā ʻano kāne, e like me ka hoʻonui ʻana o ka lauoho o ke kino (ʻoi loa ma ka maka), ka lauoho pubic, huehue, ka hohonu o ka leo, a me nā clitoris hoʻonui ʻia (wahine)

ʻO nā ʻōuli o ka hoʻonui aldosterone e like ia me nā ʻōuli o ka potassium haʻahaʻa, a pākuʻi ʻia:

• Pākuʻi kaʻiʻo
• Nawaliwali
• ʻEha ma ka ʻōpū

E hana ka mea mālama ola i kahi hoʻokolohua kino a nīnau e pili ana i kāu mau hōʻailona.

E hana ʻia nā hoʻokolohua koko e nānā i nā pae hormone:

• E haʻahaʻa ka pae ʻo ACTH.
• E kiʻekiʻe ka pae ʻo Aldolone.
• E kiʻekiʻe ka pae o Cortisol.
• E haʻahaʻa ka pae pāʻina.
• Hiki i nā kāne a i ʻole wahine wahine ke kiʻekiʻe kiʻekiʻe.

Hiki i nā hoʻokolohua kiʻi o ka ʻōpū ke komo pū:

• Kukuna ultrasound
• CT scan
• MRI
• Scanner PET

ʻO ka lapaʻau mua ka ʻoki kino e hemo ai i ka tumo. ʻAʻole hoʻomaikaʻi paha ʻo ACC me chemotherapy. Hāʻawi ʻia nā lāʻau e hōʻemi ai i ka hana o ka cortisol, ka mea e nui ai nā ʻōuli.

Aia ka hopena i ka wanaʻao e hana ʻia ai ke kuhi a inā ua pāhola ka tumo (metastasized). ʻO nā tumors i pālahalaha maʻamau e alakaʻi i ka make ma waena o 1 a 3 mau makahiki.

Hiki i ka tumo ke pālahalaha i ke ake, ka iwi, ka māmā, a i ʻole nā ​​wahi ʻē aʻe.

Kāhea i kāu mea hāʻawi inā ʻo ʻoe a ʻo kāu keiki paha nā ʻōuli o ACC, Cushing Syndrome, a i ʻole ʻole e ulu.

Tumor - adrenal; ACC - adrenal

• Nānā Endocrine
• Nā metastases Adrenal - CT scan
• Tumena Adrenal - CT

Allolio B, Fassnacht M. Adrenocortical maʻi kanesa. I: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Makua a Pediatric. ʻEpekema 7 Piladelapia, PA: Elsevier Saunders; 2016: chap 107.

Pūnaewele ʻo National Cancer Institute. Hoʻomaʻamaʻa Adrenocortical carcinoma (makua) (PDQ) - mana ʻoihana olakino. www.cancer.gov/types/adrenocortical/hp/adrenocortical-treatment-pdq. Hoʻohou Nowemapa 13, 2019. Loaʻa iā ʻOkakopa 14, 2020.