ʻO ka toxoplasmosis hānau
Congenital toxoplasmosis kahi hui o nā ʻōuli i hiki ke loaʻa i kahi pēpē i hānau ʻole ʻia (fetus) me ka parasite Toxoplasma gondii.
Hiki ke hoʻoili ʻia i ka maʻi Toxoplasmosis i kahi pēpē e ulu ana inā maʻi ka makuahine i ka wā e hāpai ana. Hoʻolahalaha ka maʻi i ka pēpē e ulu ana a puni ka placenta. ʻO ka hapa nui o ka manawa, akahai ka maʻi i ka makuahine. ʻAʻole maopopo paha ka wahine he parasite kāna. Eia nō naʻe, hiki i ka maʻi o ke pēpē ulu ke hana i nā pilikia koʻikoʻi. ʻOi aku ka maikaʻi o nā pilikia inā kū ka maʻi i ka hāpai mua.
A i ka hapalua o nā pēpē i lilo i maʻi me ka toxoplasmosis i ka wā o ka hāpai ʻana e hānau mua ʻia (prematurely). Hiki i ka maʻi ke hoʻopōʻino i nā maka o ka pēpē, ʻōnaehana ʻōnaehana, ʻili, a me nā pepeiao.
ʻO ka pinepine, aia nā hōʻailona o ka maʻi i ka wā hānau. Eia nō naʻe, ʻaʻole e loaʻa nā ʻōuli i nā pēpē me nā maʻi ʻoluʻolu no nā mahina a mau makahiki paha ma hope o ka hānau ʻana. Inā mālama ʻole ʻia, ulu ka hapanui o nā keiki me kēia maʻi i nā pilikia i kā lākou ʻōpio. Maʻamau nā pilikia o ka maka.
Pākuʻi ʻia paha nā ʻōuli:
- Hoʻonui i ke ake a me nā ʻāpala
- ʻO ka luaʻi
- Poino ka maka mai ka mumuna o ka retina a i ʻole nā ʻāpana o ka maka
- Nā pilikia hānai
- Lohe hoʻolohe
- Jaundice (ʻili melemele)
- Kaumaha hānau haʻahaʻa (ka palena ulu ulu intrauterine)
- ʻLapa ʻili (nā wahi ʻulaʻula liʻiliʻi a palapū paha) i ka wā hānau
- Nā pilikia ʻike
Hoʻopilikia ka lolo a me ka ʻōnaehana ʻōnaehana i ke akahai a i ʻole koʻikoʻi, a hiki pū me:
- Ka hopu ʻana i nā maʻi
- Kīnā ʻole o ka noʻonoʻo
E nānā ka mea mālama ola i ka pēpē. Loaʻa paha i ka pēpē:
- Kāpena pehu a me ke ake
- ʻIli melemele (jaundice)
- Huʻi o nā maka
- Fluid ma ka lolo (hydrocephalus)
- Pehu nā lymph nodes (lymphadenopathy)
- Ka nui o ke poʻo (macrocephaly) a i ʻole ka liʻiliʻi o ka nui o ke poʻo (microcephaly)
ʻO nā hoʻāʻo e hiki ke hana ʻia i ka wā hāpai hāpai:
- ʻO ka hoʻāʻo ʻana i ka wai Amniotic a me ka hoʻāʻo ʻana i ke koko fetal
- Antibody titer
- Ultrasound o ka ʻōpū
Ma hope o ka hānau ʻana, hana ʻia paha kēia mau hoʻokolohua ma luna o ka pēpē.
- ʻImi Antibody ma ke kahe o ke koko a me ka wai cerebrospinal
- CT scan o ka lolo
- MRI scan o ka lolo
- Nā hōʻike Neurological
- Hōʻike maka maʻamau
- Hōʻike Toxoplasmosis
Hiki i ka Spiramycin ke mālama i ka maʻi i ka makuahine hāpai.
Hiki i ka Pyrimethamine a me ka sulfadiazine ke mālama i ka maʻi fetal (ʻike ʻia i ka wā o ka hāpai ʻana).
ʻO ka mālama ʻana i nā pēpē me ka toxoplasmosis congenital e pili pinepine ana i ka pyrimethamine, sulfadiazine, a me leucovorin no hoʻokahi makahiki. Hāʻawi ʻia nā pēpē i kekahi manawa i nā steroid inā hoʻoweliweli ʻia kā lākou ʻike a i ʻole ke kiʻekiʻe o ka protein i loko o ka wai spinal.
Pili ka hopena i ka nui o ke ʻano.
Komo pū nā pilikia:
- ʻO Hydrocephalus
- Ka makapō a me ke kīnā kīnā ʻole
- ʻO ke kīnā koʻikoʻi koʻikoʻi a i ʻole nā pilikia neurological
Kāhea i kāu mea mālama ola inā hāpai ʻoe a noʻonoʻo ʻoe ua makaʻu ʻoe i ka maʻi. (ʻO kahi laʻana, hiki ke hele i ka maʻi toxoplasmosis mai nā pōpoki inā ʻoe e hoʻomaʻemaʻe i ka pahu ʻōpala o ka pōpoki.) Kāhea i kāu mea hāʻawi inā hāpai ʻoe a ʻaʻole i mālama mua ʻia.
ʻO nā wahine hāpai a hoʻolālā paha e hāpai e hiki ke hoʻāʻo e ʻike inā pilikia lākou i ka maʻi.
ʻO nā wahine hāpai i nā pōpoki e like me nā holoholona hale e ʻoi aku paha ka makaʻu. Pono lākou e hōʻalo i ka launa ʻana me nā feces o ka pōpoki, a i ʻole nā mea i hiki ke hoʻohaumia ʻia e nā mea kolo i hōʻike ʻia i nā fites o nā pōpoki (e like me nā ʻāʻī a me nā lele)
Eia kekahi, e kuke i kaʻiʻo a hiki i ka wā e hana maikaʻi ai, a holoi i kou mau lima ma hope o ka lawelawe ʻana i ka ʻiʻo maka e hōʻalo i ka loaʻa ʻana o ka parasite.
- ʻO ka toxoplasmosis hānau
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McLeod R, Boyer KM. Toxoplasmosis (Toxoplasma gondii). I: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. ʻO Puka Textbook of Pediatrics ʻo Nelson. 21st ed. Piladelapia, PA: Elsevier; 2020: chap 316.
Montoya JG, Boothroyd JC, Kovacs JA. Toxoplasma gondii. I: Bennett JE, Dolin R, Blaser MJ, hua pā. ʻO Mandell, Douglas, a me Bennett's Principal a me ka hoʻomaʻamaʻa ʻana i nā maʻi kūpikipiki, Hoʻopuka Hou. 8th ed. Piladelapia, PA: Elsevier Saunders; 2015: chap 280.