ʻO Moʻoiko

ʻO ka Mosaicism kahi ʻano i loaʻa i nā hunaola i loko o ka mea like ke ʻano ʻokoʻa ʻokoʻa. Hiki i kēia ʻano ke hoʻololi i kekahi ʻano o ke kelepona.

• Nā pūnaewele koko
• Nā huna hua moa a me nā sperm
• Nā ʻili ʻili

Hoʻokumu ʻia ka Mosaicism e kahi hemahema i ka mahele o ke kelepona i ke kakahiaka nui i ka ulu ʻana o ka pēpē i hānau ʻole ʻia. Eia kekahi laʻana o ka mosaicism:

• ʻO Mosaic Down Syndrome
• ʻO Mosaic Klinefelter maʻi maʻi
• ʻO Mosaic Turner maʻi maʻi

Hoʻololi nā ʻōuli a paʻakikī loa i ka wānana. ʻAʻole paʻakikī paha nā ʻōuli inā loaʻa iā ʻoe nā pūnaewele maʻamau a ʻino hoʻi.

Hiki i ka hoʻāʻo genetic ke kuhikuhi i ka mosaicism.

Pono paha e hana hou i nā hoʻāʻo e hōʻoia i nā hopena, a kōkua i ka hoʻoholo ʻana i ke ʻano a me ke koʻikoʻi o ka maʻi.

E pili ka mālama ʻana i ke ʻano a me ke koʻikoʻi o ka maʻi. Hiki paha iā ʻoe ke hōʻemi i ka hoʻomaʻamaʻa ikaika inā wale nō kekahi o nā keena ʻokoʻa.

Maikaʻi kāu hilinaʻi ʻana i nā ʻōpala a me nā mea i hoʻopili ʻia (e laʻa me ka lolo a me ka puʻuwai). He paʻakikī e wānana i nā hopena o ka loaʻa ʻana o nā laina pūnaewele ʻelua i hoʻokahi kanaka.

Ma ke ʻano laulā, ʻike like ka poʻe me ka nui o nā hunaola ʻino e like me ka poʻe me ke ʻano maʻamau o ka maʻi (ka poʻe i loaʻa nā hunaola āpau). Kāhea ʻia ke ʻano hiʻohiʻona ʻaʻohe mosaic.

ʻO ka poʻe me kahi helu haʻahaʻa o nā hunaola ʻino e hoʻopili wale ʻia. ʻAʻole paha lākou e ʻike he mosaicism kā lākou a hiki i ka wā e hānau ai lākou i kahi keiki i loaʻa ka ʻano non-mosaic o ka maʻi. I kekahi manawa ʻaʻole ola ke keiki i hānau ʻia me ka non-mosaic form, akā e ola kahi keiki i hānau ʻia me ka mosaicism.

Pili ka pilikia i ka nui o nā hunaola e loli i ka loli.

ʻO kahi kuhi o ka mosaicism ke kumu o ka huikau a me ka maopopo ʻole. Hiki i ke kākā'ōlelo genetic ke kōkua i ka pane ʻana i nā nīnau e pili ana i ka ʻike a me ka hoʻāʻo ʻana.

ʻAʻohe ala i ʻike ʻia i kēia manawa e pale aku ai i ka mosaicism.

Mosaicism Chromosomal; ʻO mosaicism Gonadal

ʻO Driscoll DA, Simpson JL, Holzgreve W, Otaño L. Ke kānana genetic a me ka prenatal genetical diagnosis. I: Gabbe SG, Niebyl JR, Simpson JL, et al, eds. Nā Obstetrics: Nā Pregnancies Maʻamau a me nā pilikia. ʻEpekema 7 Piladelapia, PA: Elsevier; 2017: chap 10.

Nussbaum RL, McInnes RR, Willard HF. ʻIke Prenatal a me ka kānana ʻana. I: Nussbaum RL, McInnes RR, Willard HF, hua. ʻO Thompson lāua ʻo Thompson Genetics i ka Lapaʻau. 8th ed. Piladelapia, PA: Elsevier; 2016: chap 17.