Hyperthermia malignant

ʻO Malignant hyperthermia (MH) kahi maʻi e piʻi wikiwiki ai ka mahana o ke kino a me nā kuʻikuʻi paʻakikī i ka wā e loaʻa ai ka maʻi anesthesia i kekahi me MH. Ua hala ʻo MH i loko o nā ʻohana.

Hyperthermia ʻo ia hoʻi ka mahana o ke kino kiʻekiʻe. ʻAʻole like kēia ʻano me hyperthermia mai nā pilikia olakino e like me ka hahau wela a i ʻole ka maʻi.

Ua hoʻoilina ʻo MH. Hoʻokahi wale nō makua e hāpai i ka maʻi no ke keiki e hoʻoilina i ke ʻano.

Hiki paha ia me kekahi mau maʻi ʻili hoʻoilina i hoʻoilina ʻia, e like me myopathy multiminicore a me maʻi maʻi waena.

ʻO nā ʻōuli o MH nā:

• Kahena
• Mimi ʻeleʻeleʻeleʻele (ma muli o kahi protein protein i kapa ʻia myoglobin i ka mimi)
• ʻEha ka ʻeha me ke kumu ʻole, e like me ka hoʻoikaika kino a ʻeha paha
• Pā paʻakikī me ka ʻoʻoleʻa
• E piʻi i ka mahana o ke kino i 105 ° F (40.6 ° C) a i ʻole ke kiʻekiʻe

ʻIke pinepine ʻia ʻo MH ma hope o ka hāʻawi ʻia ʻana o kahi kanaka anesthesia i ka wā o ke ʻoki.

Aia paha he moʻolelo ʻohana o MH a i ʻole make make ʻole i wehewehe ʻia i ka wā anesthesia.

Hiki paha i ke kanaka ke wikiwiki a pinepine i ka helu o ka puʻuwai.

Pākuʻi ʻia paha nā hoʻāʻo no MH:

• Ke hoʻopaʻa nei i ke kāpili ʻana o ke koko (PT, a i ʻole ka manawa prothrombin; PTT, a i ʻole ka manawa thromboplastin hapa)
• ʻO ke kōmika kemika koko, e like me CK (creatinine kinase, ʻoi aku ke kiʻekiʻe i ke koko ke luku ʻia nā mākala i ka wā o ka maʻi)
• ʻO ka hoʻāʻo genetic e nānā no nā kīnā i nā gen i hoʻopili ʻia me ka maʻi
• ʻO Biopsy Muscle
• Myoglobin mimi (protein protein)

I loko o kahi mahele o MH, hāʻawi pinepine ʻia kahi lāʻau i kapa ʻia dantrolene. Hiki i ka wahī ʻana i ke kanaka i kahi pale hoʻoluʻu ke kōkua i ka hōʻemi ʻana i ka fiva a me ka pilikia o nā pilikia koʻikoʻi.

E mālama ai i ka hana o ke kīʻaha i ka wā o ka hopena, hiki i ke kanaka ke loaʻa nā wai ma o ka aa.

Hiki i kēia mau kumuwaiwai ke hāʻawi i ka ʻike hou aku e pili ana iā MH:

• ʻO ka Hui Hyperthermia Malignant o ʻAmelika Hui Pū ʻIa - www.mhaus.org
• National Organization for Rare Disorder - rarediseases.org/rare-diseases/malignant-hyperthermia
• NIH Genetics Home Reference - ghr.nlm.nih.gov/condition/malignant-hyperthermia

Hiki i nā ʻāpana i hana hou ʻia a i ʻole mālama ʻole ʻia ke kumu o ka holo pono ʻole ʻana o ka hakuʻala. Hiki ke make i nā ʻāpana i hana ʻole ʻia.

Hiki i kēia mau pilikia koʻikoʻi ke kū:

• Hoʻoikaika
• Wāwahi o nāʻiʻo o ka mākala
• ʻO ka pehu ʻana o nā lima a me nā wāwae a me nā pilikia me ke kahe o ke koko a me ka hana nerve (compart Syndrome)
• Make
• Hoʻopili koko maʻamau a me ke kahe ʻana o ke koko
• Nā pilikia puʻuwai puʻuwai
• Hewa ʻole nā ​​hakuʻala
• ʻO ka buildup o ka waikawa i ke kino o ka wai (metabolic acidosis)
• Kūkulu ka wai i nā akemāmā
• Nāwaliwali a hemahema paha nā mākala (myopathy a i ʻole muscular dystrophy)

Inā ʻoe e pono i kahi ʻoki, e haʻi i kāu kaukoki a me ka anesthesiologist ma mua o ke ʻoki ʻana inā:

• ʻIke ʻoe he pilikia paha kāu a i ʻole kekahi lālā o kou ʻohana me ka anesthesia ākea
• ʻIke ʻoe he moʻolelo ʻohana kāu no MH

ʻO ka hoʻohana ʻana i kekahi mau lāʻau e hiki ke pale aku i nā pilikia o MH i ke kahakaha ʻana.

E haʻi i kāu mea mālama ola ma mua o ka hoʻokau ʻana me ka anesthesia āpau, inā ʻo ʻoe a ʻo kekahi paha i kou ʻohana he MH.

Hōʻalo i nā lāʻau stimulant e like me cocaine, amphetamine (wikiwiki), a me ka ecstasy. Hoʻokumu paha kēia mau lāʻau i nā pilikia e like me ka MH i ka poʻe i ʻike pinepine ʻia i kēia ʻano.

Paipai ʻia ka ʻōlelo aʻoaʻo genetic no kēlā me kēia me ka moʻolelo ʻohana o myopathy, mustrular dystrophy, a me MH paha.

Hyperthermia - hōʻino; Hyperpyrexia - hōʻino; MH

ʻAhahui ʻAmelika o nā Nurse Anesthetists. Hoʻomākaukau a me ka mālama ʻana i ka pilikia hyperthermia malignant: ka ʻōlelo kūlana. www.aana.com/docs/default-source/practice-aana-com-web-documents-(all)/malignant-hyperthermia-crisis-preparedness-and-treatment.pdf?sfvrsn=630049b1_8. Hoʻohou ʻia ʻApelila 2018. Loaʻa iā Mei 6, 2019.

Kulaylat MN, Dayton MT. Nā pilikia ʻoki kino. I: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. ʻO Sabiston Textbook of Surgery. 20 ouk. Piladelapia, PA: Elsevier; 2017: chap 12.

Zhou J, Bose D, Allen PD, Pessah IN. ʻO ka hyperthermia malignant a me nā maʻi e pili ana i ka mākala. I: Miller RD, ed. Miller Anesthesia. 8th ed. Piladelapia, PA: Elsevier Saunders; 2015: chap 43.