Neurosyphilis

ʻO Neurosyphilis kahi maʻi bacteria o ka lolo a i ʻole ka iwi maha. Hana ʻia ia i ka poʻe i loaʻa ʻole ka syphilis i mālama ʻole ʻia no nā makahiki he nui.

Hoʻokumu ʻia ʻo Neurosyphilis e Treponema pallidum. ʻO kēia ka maʻi bacteria e kumu ai ka syphilis. Kū pinepine ʻo Neurosyphilis ma kahi o 10 a 20 mau makahiki ma hope o ka maʻi mua o ke kanaka me ka syphilis. ʻAʻole nā ​​poʻe i loaʻa ka syphilis e hoʻomōhala i kēia pilikia.

ʻEhā ʻano ʻokoʻa o neurosyphilis:

• Asymptomatic (ʻano maʻamau)
• Paresis laulaha
• Meningovascular
• Tabes dorsalis

Hana ʻia ʻo neurosyphilis Asyimtomatik ma mua o ka syphilis. ʻAʻohe o ka hōʻailona hōʻailona.

Hoʻopili pinepine nā ʻōuli i ka ʻōnaehana hopohopo. Kaukaʻi ʻia i ke ʻano o neurosyphilis, hiki i nā ʻōuli ke hoʻopili i kekahi o kēia mau mea:

• Hele wāwae maʻamau (hele wāwae), a i ʻole hiki ʻole ke hele wāwae
• Pōpō i nā manamana wāwae, nā wāwae, a me nā wāwae
• Nā pilikia me ka noʻonoʻo, e like me ka huikau a i ʻole ka noʻonoʻo maikaʻi ʻole
• Nā pilikia o ka noʻonoʻo, e like me ke kaumaha a me ka huhū
• ʻEha poʻo, ka hopu ʻana a i ʻole ʻāʻī ʻoʻoleʻa
• Ka nalowale o ka mālama ʻana i ka bladder (incontinence)
• Nā haʻalulu, a nāwaliwali paha
• Nā pilikia ʻike, a ʻo ka makapō hoʻi

E hana ana kāu mea mālama ola i kahi hoʻokolokolo kino a loaʻa paha iā ia ka mea aʻe:

• Nā reflexes maʻamau
• ʻAtope Muscle
• Pākuʻi mākala
• Hoʻololi manaʻo

Hiki ke hana i nā hoʻokolohua koko e ʻike i nā mea i hana ʻia e nā bacteria e hoʻokumu i ka syphilis, ʻo kēia pū kekahi:

• Treponema pallidum hoʻoliʻiliʻi hoʻohuihui (TPPA)
• Hōʻike ʻimi noiʻi maʻi maʻi Venereal (VDRL)
• Ka omo treponemal fluorescent (FTA-ABS)
• ʻO ka reagin plasma wikiwiki (RPR)

Me nā neurosyphilis, he mea nui e hoʻāʻo i ka wai ākea no nā hōʻailona o syphilis.

ʻO nā hoʻāʻo e nānā i nā pilikia me ka ʻōnaehana hopohopo e hoʻopili pū paha:

• Cerebral angiogram
• Poʻomanaʻo CT poʻo
• Lumbar puncture (spinal tap) a me ka cerebrospinal fluid (CSF) kālailai
• MRI scan o ka lolo, ʻōnaehana lolo, a i ʻole ka iwi kuamoʻo

Hoʻohana ʻia ka penicillin antibiotic e mālama ai i ka neurosyphilis. Hiki ke hāʻawi ʻia i nā ʻano like ʻole:

• Hoʻokomo ʻia i loko o ke aa i nā manawa he nui i ka lā no 10 a 14 mau lā.
• Ma ka waha 4 mau manawa i ka lā, hui pū ʻia me nā injection o nā mākala i kēlā me kēia lā, lawe ʻelua ʻia no 10 a 14 mau lā.

Pono ʻoe e mālama i nā hoʻokolohua koko ma 3, 6, 12, 24, a me 36 mau mahina e ʻike pono ua hala ka maʻi. Pono ʻoe i nā punctures lumbar ukali no ka hoʻoponopono CSF ​​i kēlā me kēia 6 mahina. Inā loaʻa iā ʻoe ka maʻi HIV / AIDS a i ʻole ke ʻano olakino ʻokoʻa, ʻokoʻa paha kāu papa hana ukali.

ʻO Neurosyphilis kahi pōpilikia hoʻoweliweli ola o syphilis. Maikaʻi kāu hilinaʻi ʻana i ka nui o ka neurosyphilis ma mua o ka mālama ʻana. ʻO ka pahuhopu o ka mālama ʻana e pale i ka hōʻino hou ʻana. ʻAʻole hiki ke hoʻololi i ka hapa nui o kēia mau hoʻololi.

Hiki i nā ʻōuli ke piʻi mālie.

Kāhea i kāu mea hāʻawi inā loaʻa iā ʻoe ka syphilis i ka wā ma mua a i kēia manawa he mau hōʻailona o nā pilikia ʻōnaehana.

ʻO ka hōʻoia koke a me ka mālama ʻana i ka maʻi syphilis kumu hiki ke pale aku i ka neurosyphilis.

Syphilis - neurosyphilis

• ʻŌnaehana ʻōnaehana waena a me ka ʻōnaehana ʻōnaehana peripheral
• Syphilis pae hope

Euerle BD. ʻO ka puncture a me ka nānā ʻana i ka wai cerebrospinal. I: Roberts JR, Custalow CB, Thomsen TW, eds. ʻO Roberts a me Hedges 'Nā Kauka Lapaʻau i ka Medicine Emergency a me ka Care Acute. ʻEpekema 7 Piladelapia, PA: Elsevier; 2019: chap 60.

National Institute of Neurological Disorder a me ka pūnaewele Stroke. Neurosyphilis. www.ninds.nih.gov/Disorders/All-Disorders/Neurosyphilis-Information-Page. Hoʻohou ʻia Malaki 27, 2019. Loaʻa iā Pepeluali 19, 2021.

Radolf JD, Tramont EC, Salazar JC. Syphilis (Treponema pallidum). I: Bennett JE, Dolin R, Blaser MJ, hua pā. ʻO Mandell, Douglas, a me Bennett's Principle a me ka hoʻomaʻamaʻa ʻana i nā maʻi kūpilikiʻi. 9th ed. Piladelapia, PA: Elsevier; 2020: chap 237.