ʻO Waterhouse-Friderichsen maʻi

ʻO Waterhouse-Friderichsen Syndrome (WFS) kahi hui o nā ʻōuli e hopena ana ma muli o ka holo pono ʻole o ka adrenal glands e hana maʻamau ma muli o ke kahe ʻana i ke kahena.

ʻO nā glands adrenal ʻelua mau gland triangle-shaped. Aia kekahi gland ma luna o kēlā me kēia puʻupaʻa. Hana a hoʻokuʻu nā adrenal glands i nā hormoni like ʻole e pono ai ke kino e hana maʻamau. Hiki ke hoʻopili ʻia nā ʻōpū adrenal e nā maʻi he nui, e like me nā maʻi e like me WFS.

Hoʻokumu ʻia ʻo WFS e ka maʻi nui loa me nā koʻohune meningococcus a i ʻole nā ​​bacteria ʻē aʻe, e like me:

• Pūʻulu B streptococcus
• Pseudomonas aeruginosa
• ʻO Streptococcus pneumoniae
• Staphylococcus aureus

Kū koke nā ʻōuli. Pili lākou i nā hua bacteria e ulu (hoʻonui nei) i loko o ke kino. ʻO nā hōʻailona me:

• Fiva a me nā anuanu
• ʻEha pū me ka ʻeha pū
• ʻEha poʻo
• ʻO ka luaʻi

ʻO ka maʻi me nā koʻohune ke kumu o ke kahe ʻana o ke kino, nā kumu:

• ʻWidehū kino
• Hoʻomaʻemaʻe i ka coagulation intravascular kahi e ʻoki ai ke koko liʻiliʻi i nā lako o ke koko
• Hoʻoweliweli Septic

ʻO ke kahe ʻana i loko o nā ʻōpū adrenal ke kumu o ka pilikia adrenal, kahi e hana ʻole ʻia ai nā homone adrenal. Alakaʻi kēia i nā ʻōuli e like me:

• Puʻupuʻu, nāwaliwali
• Ke kaomi haʻahaʻa haʻahaʻa loa
• ʻO ka helu wikiwiki o ka naʻau
• Huikau a koma paha

E hana ka mea mālama ola i kahi hoʻokolokolo kino a nīnau e pili ana i nā ʻōuli o ke kanaka.

E hana ʻia nā hoʻokolohua koko e hōʻoia i kahi maʻi bacteria. E komo pū paha nā hoʻāʻo:

• Moʻomeheu Koko
• Helu piha ke koko me ka ʻokoʻa
• Nā hoʻopaʻa haʻawina koko

Inā kānalua ka mea hāʻawi i ka maʻi maʻi i hoʻokumu ʻia e ka bacteria bacteria meningococcus, nā hoʻokolohua ʻē aʻe i hiki ke hana ʻia e:

• Lumbar puncture e kiʻi i kahi laʻana o ka spinal fluid no ka moʻomeheu
• ʻO ka maʻi biopsy o ka ʻili a me ka Gram
• Loiloi mimi

Nā hoʻokolohua i kauoha ʻia paha e kōkua i ke kuhi hewa ʻana me ka pilikia adrenal koʻikoʻi:

• Hōʻike hoʻonāukiuki ACTH (cosyntropin)
• Hōʻike koko Cortisol
• Koko kō
• Hōʻike koko potassium
• Hōʻike koko Sodium
• Hōʻaʻo pH koko

Hoʻomaka koke ʻia nā antibiotic e mālama i ka maʻi bacteria. Hāʻawi ʻia nā lāʻau Glucocorticoid e mālama i ka lawa ʻole o ka adrenal gland. Pono nā lāʻau kākoʻo no nā ʻōuli ʻē aʻe.

He mea make ʻo WFS ke ʻole e hoʻomaka koke ka mālama ʻana i ka maʻi bacteria a hāʻawi ʻia nā lāʻau a glucocorticoid.

I mea e pale aku ai i ka WFS i hoʻokumu ʻia e nā koʻohune meningococcal, loaʻa kahi lāʻau lapaʻau.

Fulminant meningococcemia - Waterhouse-Friderichsen maʻi; Fulminant meningococcal sepsis - Waterhouse-Friderichsen maʻi; Adrenalitis hemorrhagic

• Nā liona Meningococcal ma ke kua
• Huna ka adrenal gland hormone

Stephens DS. Meningitides Neisseria. I: Bennett JE, Dolin R, Blaser MJ, hua pā. ʻO Mandell, Douglas, a me Bennett's Principle a me ka hoʻomaʻamaʻa ʻana i nā maʻi kūpilikiʻi. 9th ed. Piladelapia, PA: Elsevier Saunders; 2020: chap 211.

ʻO Newell-Price JDC, Auchus RJ. ʻO ka Cortex adrenal. I: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. ʻO Williams Textbook of Endocrinology. 14th ed. Piladelapia, PA: Elsevier; 2020: chap 15.