Hoʻokomo ʻia ka anemia hemolytic immune-i hoʻowalewale ʻia e nā lāʻau

ʻO ke anemia hemolytic immune i hoʻowalewale ʻia i ka lāʻau lapaʻau he maʻi koko ia e kū ʻia i ka wā e hoʻoulu ai kahi lāʻau i ka pale o ke kino (immune) e hoʻouka i kāna mau ʻulaʻula koko ponoʻī. ʻO kēia ke kumu o ka haki ʻana o nā hunaola ʻulaʻula ma mua o ka maʻamau, kahi hana i kapa ʻia hemolysis.

ʻO ke Anemia kahi ʻano i lawa ʻole ke kino i nā hunaola ʻulaʻula olakino. Hāʻawi nā hunaola ʻulaʻula i ka oxygen i nā aʻa o ke kino.

ʻO ka maʻamau, mau ke koko i ʻulaʻula ma kahi o 120 mau lā i ke kino. I ka hemolytic anemia, hoʻopau ʻia nā hunaola ʻulaʻula i ke koko ma mua o ka maʻamau.

I kekahi mau hihia, hiki i kahi lāʻau lapaʻau ke kuhi hewa i ka ʻōnaehana pale pale i kou mau ʻulaʻula koko ponoʻī no nā mea haole. Pane ke kino i ka hana ʻana i nā mea ʻino e hoʻouka i nā kino koko ʻulaʻula o ke kino. Hoʻopili nā mea ʻino i nā hunaola ʻulaʻula a hoʻoneʻe iā lākou i ka wanaʻao.

Nā lāʻau i hiki ke kumu i kēia ʻano hememia hemolitik:

• ʻO Cephalosporins (kahi papa o nā antibiotic), ke kumu maʻamau
• ʻO Dapsone
• ʻO Levodopa
• ʻO Levofloxacin
• Methyldopa
• Nitrofurantoin
• Nā lāʻau anti-inflammatory nonsteroidal (NSAIDs)
• ʻO Penicillin a me nā mea i loaʻa mai
• Phenazopyridine (pyridium)
• Quinidine

ʻO kahi ʻano laha ʻole o ka maʻi he hemolytic anemia mai ka nele o ka glucose-6 phosphate dehydrogenase (G6PD). I kēia hihia, ʻo ka haki ʻana o nā hunaola ʻulaʻula ma muli o kekahi ʻano koʻikoʻi i loko o ke kele.

Laha ʻole ka anemia hemolytic i hoʻokomo ʻia i ka lāʻau i loko o nā keiki.

Pākuʻi ʻia paha nā ʻōuli i kekahi o kēia mau mea:

• Mimi ʻeleʻele
• Ka luhi
• Waihoʻoluʻu pale
• Helu puʻuwai wikiwiki
• Pokole o ka hanu
• ʻIli melemele a keʻokeʻo o nā maka (jaundice)

Hōʻike kahi hoʻokolohua kino i kahi lōlō hoʻonui. Loaʻa paha iā ʻoe ke koko a me nā hoʻokolohua mimi e kōkua i ke kuhi ʻana i kēia ʻano.

E komo pū paha nā hoʻāʻo:

• Helu retikulika pau loa e hoʻoholo inā e hana ʻia nā hunaola ʻulaʻula i loko o ka iwi iwi ma kahi kūpono kūpono
• Hōʻike pololei a kuhikuhi ʻole paha nā Coombs e nānā inā aia nā mea ʻino e kūʻē i nā hunaola ʻulaʻula e make ai i ke koko ʻulaʻula i ka wanaʻao
• Nā pae bilirubin kuhikuhi ʻole e nānā no ka jaundice
• Helu helu ʻulaʻula koko
• Serum haptoglobin e nānā inā e luku mua ʻia nā hunaola ʻulaʻula
• ʻO ka hemoglobin mimi e nānā ai no ka hemolysis

ʻO ke kū ʻana i ka lāʻau i hiki i ka pilikia ke hōʻoluʻolu a kāohi paha i nā ʻōuli.

Pono paha ʻoe e ʻai i ka lāʻau i kapa ʻia prednisone e kāohi ai i ka pane ʻōnaehana kūʻē i nā ʻulaʻula koko. Pono paha ke kipi koko kūikawā e mālama i nā ʻōuli koʻikoʻi.

Maikaʻi ka hopena no ka hapanui o ka poʻe inā kū lākou i ka lawe ʻana i ka lāʻau i hiki i ka pilikia.

Kākaʻikahi ka make ma muli o ka anemia koʻikoʻi.

E ʻike i kāu mea mālama ola inā loaʻa nā ʻōuli o kēia ʻano.

Hōʻalo i ka lāʻau i hoʻokumu i kēia ʻano.

Immune hemolytic maʻi pale lua i nā lāʻau lapaʻau; Anemia - pale hemolytic - kekona i nā lāʻau

• Nā Antibodies

ʻO Michel M. Autoimmune a me nā anemias hemolytic intravascular. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil. 25th hua. Piladelapia, PA: Elsevier Saunders; 2016: chap 160.

Lanakila N, Richards SJ. Loaʻa i nā anaemias haemolytic. I: Bain BJ, Bates I, Laffan MA, eds. ʻO Dacie lāua ʻo Lewis Hematology Pono. 12th ed. Piladelapia, PA: Elsevier; 2017: chap 13.