Insipidus maʻi ʻaʻ Central

ʻO ka insipidus diabetes kūpilikiʻi kahi kūlana maʻamau e pili ana i ka make wai loa a me ka nui o ka urination.

ʻO ka Diabetes insipidus (DI) kahi kūlana maʻamau ʻole i hiki ʻole i nā puʻupaʻa ke pale i ka excretion o ka wai. He maʻi ʻokoʻa ʻo DI ma mua o ka maʻi diabetes, ʻoiai ua like like nā ʻelua i nā ʻōuli maʻamau o ka nui o ka urination a me ka make wai.

ʻO ka insipidus Central diabetes kahi ʻano o DI e hiki ke loaʻa ke kino ma lalo o ka nui maʻamau o ka antidiuretic hormone (ADH). Kāhea ʻia ʻo ADH vasopressin. Hana ʻia ʻo ADH ma kahi ʻāpana o ka lolo i kapa ʻia ʻo hypothalamus. Mālama ʻia ʻo ADH a hoʻokuʻu ʻia mai ka pituitary gland. He gland liʻiliʻi kēia ma ke kumu o ka lolo.

Mālama ʻo ADH i ka nui o ka wai i excreted i ka mimi. Me ka ʻole o ADH, ʻaʻole holo pono nā puʻupaʻa e mālama pono i ka wai i loko o ke kino. ʻO ka hopena he poho wikiwiki o ka wai mai ke kino i ke ʻano o ka mimiki dilute. ʻO kēia ka hopena i ka pono e inu i ka nui o ka wai ma muli o ka make wai loa a no ka make nui ʻana o ka wai i ka mimi (10 a 15 liters o ka lā).

Hoʻokumu ʻia ka pae hōʻemi o ADH e ka hōʻino ʻia o ka hypothalamus a i ʻole ka pituitary gland. ʻO kēia ʻino ma muli o ke kaha ʻana, ka maʻi, ka pehu, ka tumo a i ʻole ka ʻeha o ka lolo.

I nā hihia maʻamau, hoʻokumu ʻia ka insipidus diabetes waena e kahi pilikia pilikino.

ʻO nā ʻōuli o ka insipidus diabetes waena:

• Hoʻonui i ka hana mimi
• Make wai nui loa
• Huikau a hoʻololi i ka makaʻala ma muli o ka make wai a me ke kiʻekiʻe ma mua o ka pae sodium maʻamau i ke kino, inā ʻaʻole hiki i ke kanaka ke inu.

E nīnau ka mea mālama ola e pili ana i kāu mōʻaukala a me nā ʻōuli.

ʻO nā hoʻokolohua i kauoha ʻia e komo pū:

• ʻO ka sodium sodium a me osmolarity
• Desmopressin (DDAVP) ʻaʻa
• MRI o ke poʻo
• Urinalysis
• Piʻipiʻi kōmi
• Pihi mimi

E mālama ʻia ke kumu o ke kumu paʻa.

Hāʻawi ʻia ʻo Vasopressin (desmopressin, DDAVP) ma ke ʻano he spray nasal, tablets, a injection paha. Mālama kēia i ka puka mimi a me ke kaulike wai a pale i ka make wai.

I nā hihia maʻalahi, ʻo ka inu ʻana i ka wai hou aku ka mea e pono ai. Inā ʻaʻole holo ka make wai o ke kino (e laʻa, inā hōʻino ʻia ka hypothalamus), pono paha kahi palapala no kahi nui o ka lawe ʻana i ka wai e hōʻoia i ka hydration kūpono.

Pili ka hopena i ke kumu. Inā mālama ʻia, ʻaʻohe kumu o nā pilikia nui a i ʻole ka hopena i ka make mua i ka maʻi diabetes maʻamau.

ʻO ka inu ʻole ʻana i nā wai a hiki ke alakaʻi i ka make wai a me ke kaulike ʻole electrolyte.

Ke lawe ʻole i ka vasopressin a me ka mālama make wai o kou kino i maʻamau ʻole, inu ka nui o nā wai ma mua o kou kino e hiki ai ke hoʻoweliweli i ke kaulike electrolyte.

Kāhea i kāu mea nāna e hāʻawi inā hoʻomohala ʻoe i nā ʻōuli o ka maʻi maʻi diabetes waena.

Inā loaʻa iā ʻoe kahi insipidus diabetes waena, e hoʻopili aku i kāu mea hāʻawi inā pinepine ka urination a i ʻole ka make wai nui loa.

ʻAʻole hiki ke pale ʻia ka hapa nui o nā hihia. ʻO ka mālama koke ʻana i nā maʻi, nā tumors, a me nā ʻeha e hōʻemi paha i ka makaʻu.

Diabetes insipidus - waena; ʻO ka insipidus diabetes Neurogenic

• ʻO ka hana Hypothalamus hormone

Brimioulle S. Diabetes insipidus. I: ʻO Vincent J-L, ʻo Abraham E, Moore FA, Kochanek PM, Fink MP, eds. Puke aʻo o ka mālama koʻikoʻi. ʻEpekema 7 Piladelapia, PA: Elsevier; 2017: chap 150.

ʻO Giustina A, Frara S, Spina A, Mortini P. Ke hypothalamus. I: Melmed S, ed. Ka Pituitary. ʻEhā ed. Piladelapia, PA: Elsevier; 2017: chap 9.

Moritz ML, Ayus JC. ʻO ka insipidus diabetes a me ka maʻi o ka hormone antidiuretic kūpono. I: Singh AK, Williams GH, eds. Puke puke o Nefro-Endocrinology. ʻElua ed.Piladelapia, PA: Elsevier; 2018: chap 8.