ʻO ka lupus erythematosus ʻōnaehana

ʻO ka systemic lupus erythematosus (SLE) kahi maʻi autoimmune. I kēia maʻi, hōʻeha hewa ka ʻōnaehana pale o ke kino i nāʻiʻo olakino. Hiki ke hoʻopili i ka ʻili, nā hono, nā puʻupaʻa, ka lolo, a me nā mea ʻē aʻe.

ʻAʻole maopopo leʻa ke kumu o SLE. Pili paha ia i nā kumu aʻe:

• Genetic
• Kūlohelohe
• Hormonal
• Nā lāʻau lapaʻau kekahi

ʻOi aku ka maʻamau o SLE i nā wahine ma mua o nā kāne ma kahi o 10 a 1. Hiki paha i kēlā me kēia makahiki. Eia nō naʻe, ʻike pinepine ʻia i nā wahine ʻōpio ma waena o nā makahiki 15 a me 44. I ka US, ʻoi aku ka nui o ka maʻi ma ʻAmelika ʻAmelika, ʻAmelika ʻAmelika, nā Caribbeanbe ʻApelika, a me ko ʻAmelika Hispanika.

Hoʻololi nā ʻōuli i kēlā me kēia kanaka, a hele a hele paha. Loaʻa i nā poʻe me SLE ka ʻeha pū a me ka pehu ʻana i kekahi manawa. Hoʻolālā kekahi i ka maʻi kō. Hoʻopili pinepine ʻo SLE i nā hono o nā manamana lima, nā lima, nā pulima, a me nā kuli.

ʻO nā ʻōuli maʻamau e pili pū me:

• ʻEha o ka umauma ke hanu nui.
• Ka luhi.
• Fever me kekahi kumu ʻē aʻe.
• General discomfort, uneasiness, a maʻi maʻi paha (malaise).
• Lilo ka lauoho.
• Kaumaha emi.
• ʻEha nā waha.
• ʻIke i ka lā.
• Kaʻi ʻili - Hoʻomohala ʻia kahi ʻūlū "butterfly" ma kahi o ka hapalua o ka poʻe me SLE. ʻIke ʻia ka hū ma luna o nā papalina a me ke alahaka o ka ihu. Hiki ke pālahalaha. Piʻi ʻino ia i ka lā.
• Nā pehu lymph pehu.

Pili nā ʻōuli a me nā ʻōuli ʻē aʻe i ka ʻāpana o ke kino e hoʻopili ʻia:

• ʻO ka lolo a me ka ʻōnaehana ʻōnaehana - Headache, nāwaliwali, numbness, tingling, ka hopu ʻana i nā pilikia, ʻike pilikia, hoʻomanaʻo a me nā ʻano pilikino.
• ʻAoʻao Digestive - ʻeha o ka ʻōpū, nausea, a me ka luaʻi
• Puʻuwai - Nā pilikia o ka nohona, ka puhū ʻana o ka puʻuwai puʻuwai a i ʻole ka uhi ʻana o ka naʻau (pericardium)
• Lung - Kūkulu i ka wai i ka wahi pleura, paʻakikī i ka hanu ʻana, ʻūlū i ke koko
• ʻIli - ʻeha ma ka waha
• Kidney - Ka pehu ʻana i nā wāwae
• Kaapuni - Nā kīʻaha ma nā aʻa a i ʻole nā ​​aʻa, ka mumū o nā kīʻaha koko, ka paʻa ʻana o nā kīʻaha koko i ka pane ʻana i ke anuanu (Raynaud hanana)
• ʻO nā kino kīnā ʻole o ke koko me ka anemia, ke koko koko keʻokeʻo haʻahaʻa a i ʻole ka helu platelet

Loaʻa i kekahi poʻe nā ʻōuli o ka ʻili wale nō. Kapa ʻia kēia ʻo discoid lupus.

E ʻike ʻia me ka lupus, pono ʻoe i 4 o 11 mau hōʻailona maʻamau o ka maʻi. Ma kahi kokoke i nā poʻe āpau me ka lupus i kahi hōʻike maikaʻi no ka antinuclear antibody (ANA). Eia nō naʻe, ʻo ka loaʻa ʻana o kahi ANA maikaʻi ʻaʻole ia he kumu he lupus kāu.

E hana ka mea mālama ola i kahi hōʻike kino holoʻokoʻa. Hiki paha iā ʻoe ke ʻeha, arthritis, a edema paha i nā kuʻekuʻe wāwae. Aia paha he kani ʻokoʻa i kapa ʻia he rub gesipe puʻuwai a i ʻole ʻōpala hoʻopiʻi pleura. E hana pū kāu mea hāʻawi i kahi hoʻokolohua ʻōnaehana hopohopo.

Hoʻokomo ʻia paha nā hoʻāʻo e hōʻike iā SLE:

• Antinuclear antibody (ANA)
• CBC me ka ʻokoʻa
• Pākuʻi x-ray
• Serum creatinine
• Urinalysis

Loaʻa paha iā ʻoe nā hoʻokolohua ʻē aʻe e aʻo hou aʻe e pili ana i kāu kūlana. ʻO kekahi o kēia mau mea:

• Pākuʻi antinuclear antibody (ANA)
• Nā mea hoʻohui (C3 a me C4)
• Nā Antibodies i DNA pālua
• Hōʻike Coombs - kuhikuhi
• ʻO Cryoglobulins
• ESR a me CRP
• Nā hoʻāʻo ʻana o ke kō
• Nā hoʻokolohua koko hana ate
• ʻLelo Rheumatoid
• Nā Antibroidolipid antibodies a me ka lupus anticoagulant hōʻike
• ʻO Biopsy hakuʻala
• Nā hōʻike kiʻi o ka puʻuwai, lolo, akemāmā, ami, ami a i ʻole nā ​​ʻōpū

ʻAʻohe lāʻau a SLE. ʻO ka pahuhopu o ka mālama ʻana e kaohi i nā ʻōuli. ʻO nā hōʻailona koʻikoʻi e pili ana i ka puʻuwai, nā mumū, nā puʻupaʻa, a me nā mea ʻē aʻe e pono pinepine i ka mālama ʻana e nā loea. Pono kēlā me kēia kanaka me SLE i ka loiloi e pili ana i:

• Pehea ka hana o ka maʻi
• He aha ka ʻāpana o ke kino e hoʻopili ʻia
• He aha ke ʻano o ka lapaʻau e pono ai

Hiki ke mālama ʻia nā ʻano akahai o ka maʻi me:

• Nā NSAID no nā ʻōuli hui a me ka pleurisy. E kamaʻilio me kāu mea hāʻawi ma mua o ka lawe ʻana i kēia mau lāʻau.
• ʻO nā lāʻau liʻiliʻi o nā corticosteroids, e like me prednisone, no ka ʻōuli a me nā ʻōiwi.
• ʻO nā kalima Corticosteroid no ka huehue o ka ʻili.
• ʻO Hydroxychloroquine, kahi lāʻau i hoʻohana ʻia e mālama i ka malaria.
• Hiki ke hoʻohana ʻia ka Methotrexate e hōʻemi i ka mahele lāʻau o corticosteroids
  
• ʻO Belimumab, kahi lāʻau biologic, kōkua paha i kekahi poʻe.

Hiki i nā hana no ka SLE ʻoi loa ke hoʻopili pū:

• ʻO Corticosteroids lāʻau kiʻekiʻe.
• Nā lāʻau hoʻomalu Immunosuppressive (ʻo kēia mau lāʻau ke kāohi i ka ʻōnaehana pale maʻi). Hoʻohana ʻia kēia mau lāʻau inā loaʻa ʻoe i ka lupus koʻikoʻi e hoʻopili ana i ka ʻōnaehana, nā puʻupaʻa a i ʻole nā ​​mea ʻē aʻe. Hiki paha ke hoʻohana ʻia inā ʻaʻole ʻoe e ʻoi aku ka maikaʻi me nā corticosteroids, a i ʻole inā e ʻoi aku ka maikaʻi o kāu mau hōʻailona ke kū ʻoe i ka lawe ʻana i nā corticosteroids.
• Hoʻohana pinepine ʻia nā lāʻau i mycophenolate, azathioprine a me cyclophosphamide. Ma muli o kona ʻona, kaupalena ʻia ka cyclophosphamide i kahi papa pōkole o 3 a 6 mau mahina. Hoʻohana ʻia ʻo Rituximab (Rituxan) i kekahi mau hihia.
• ʻO nā mea lahilahi o ke koko, e like me warfarin (Coumadin), no nā maʻi hōʻuluʻulu e like me ka antiphospholipid syndrome.

Inā he SLE kāu, he mea nui pū kekahi e:

• E ʻaʻahu i nā lole pale, nā aniani, a me nā pale i ka lā i ka lā.
• E mālama i ka mālama puʻuwai pale.
• E noho mau i kēia lā me nā pale ʻana.
• E loaʻa i nā hoʻāʻo e kānana no ka lahilahi o nā iwi (osteoporosis).
• Hōʻalo i ka paka a inu i ka nui o ka waiʻona.

Hiki i nā hui aʻoaʻo a me nā hui kōkua ke kōkua me nā pilikia pili i ka naʻau.

Ua hoʻomaikaʻi ka hopena o ka poʻe me SLE i nā makahiki i hala iho nei. Nui nā poʻe me SLE i loaʻa nā ʻōuli mālie. Aia ʻoe i ka maikaʻi o ka hopena o ka maʻi. ʻO ka hapa nui o ka poʻe me SLE e koi i nā lāʻau no ka manawa lōʻihi. Ma kahi kokoke i nā mea āpau e koi ʻia ʻo hydroxychloroquine i ka manawa pau ʻole. Eia nō naʻe, ma ka US, ʻo SLE kekahi o nā kumu kiʻekiʻe he 20 i ka make o nā wahine ma waena o nā makahiki he 5 a me 64. Ke aʻo ʻia nei nā lāʻau hou he nui e hoʻomaikaʻi ai i ka hopena o nā wahine me SLE.

Mālama nui ka maʻi:

• I nā makahiki mua ma hope o ka hōʻoia ʻana
• I ka poʻe ma lalo o 40 mau makahiki

Hiki i nā wahine he nui me SLE ke hāpai a hānau i kahi pēpē olakino. ʻO kahi hopena maikaʻi e ʻoi aku paha no nā wahine i loaʻa i ka lāʻau kūpono a ʻaʻohe o lākou pilikia koʻikoʻi ma ka puʻuwai a me ka puʻuwai. Eia nō naʻe, ke kū nei o kekahi mau antibodies SLE a i ʻole nā ​​antodiespolisolidid antodies e hāpai i ka pilikia o ka hāpai keiki ʻole.

NEPHRITIS LUPUS

Loaʻa i kekahi poʻe me SLE nā waihona pale pale kūlohelohe i nā hunaola ʻulaʻula. ʻO kēia ke alakaʻi i kahi ʻano i kapa ʻia ʻo lupus nephritis. Hiki i ka poʻe me kēia pilikia ke hoʻomohala i ka hakuʻala ʻole. Pono paha lākou i ka dialysis a i ʻole ke kuʻi ʻōiwi.

Hana ʻia kahi biopsy kidney e ʻike i ka nui o ka hōʻino ʻana i ka puʻupaʻa a kōkua i ke alakaʻi ʻana i ka lāʻau. Inā loaʻa kahi nephritis ʻeleu, pono ka mālama ʻana me nā lāʻau immunosuppressive me nā kaha kiʻekiʻe o nā corticosteroids me nā cyclophosphamide a i ʻole mycophenolate.

Nā ʻĀpana ʻē aʻe o ke Kino

Hiki i ka SLE ke hōʻino i nā ʻāpana like ʻole o ke kino, e like me:

• Hoʻopili ke koko i nā aʻa o nā wāwae, nā māmā, ka lolo, a me nā ʻōpū
• Ka luku ʻia ʻana o nā hunaola ʻulaʻula a i ʻole anemia o ka maʻi wā lōʻihi (mau)
• Fluid a puni ka puʻuwai (pericarditis), a i ʻole mumū o ka puʻuwai (myocarditis a i ʻole endocarditis)
• ʻO ka wai a puni nā akemāmā a me ka hōʻino ʻana i nāʻiʻo māmā
• Nā pilikia hāpai, e like me ka hāpai keiki ʻole
• Hahau
• Hoʻopilikia i ka ʻōpū me ka ʻeha o ka ʻōpū a me ka ālai
• ʻO ka hoʻohaunaele i loko o nā ʻōpū
• Ka helu haʻahaʻa platelet haʻahaʻa loa (pono nā platelet e hoʻopau i nā kahe ʻana)
• ʻO ka hoʻowahāwahā o nā kīʻaha koko

SLE A HANA HANA

Hiki i nā SLE a me kekahi o nā lāʻau i hoʻohana ʻia no SLE ke hōʻeha i kahi keiki hānau ʻole. E kamaʻilio me kāu mea hāʻawi ma mua o kou hāpai ʻana. Inā hāpai ʻoe, e ʻike i kahi mea hoʻolako i ʻike me ka lupus a me ka hāpai keiki.

Kāhea i kāu mea hāʻawi inā loaʻa iā ʻoe nā ʻōuli o SLE. Kāhea pū hoʻi inā loaʻa ʻoe i kēia maʻi a hele a hewa ʻole kāu mau ʻōuli a i ʻole kū ʻia kahi hōʻailona hou.

Pākuʻi ʻia ʻo lupus erythematosus; SLE; Lupus; Lupus erythematosus; ʻLapa butterfly - SLE; Lupus discoid

• ʻO ka lupus erythematosus ʻōnaehana
• Lupus, discoid - ʻike i nā leona ma ka umauma
• Lupus - hoʻokaʻawale i ka helehelena o ke keiki
• Hoʻoweliweli ka lupus erythematosus ʻōnaehana i ka maka
• Nā Antibodies

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