Pseudomembranous colitis

ʻO Pseudomembranous colitis e pili ana i ka pehu ʻana o ka ʻōpū nui (kolona) ma muli o ka ulu nui ʻana o Difficile ʻo Clostridioides (C difficile) koʻohune.

ʻO kēia maʻi kahi kumu maʻamau o ka diarrhea ma hope o ka hana antibiotic.

ʻO ka C difficile noho ka bacteria i loko o ka ʻōpū. Eia nō naʻe, ulu paha ka nui o kēia mau koʻohune ke lawe ʻoe i nā antibiotic. Hāʻawi ke koʻohune i kahi lāʻau make ikaika i kumu i ka wela a me ke kahe ʻana i ka pale o ke kolona.

Hiki i kekahi antibiotic ke kumu i kēia ʻano. ʻO nā lāʻau i kuleana no ka pilikia i ka hapanui o ka manawa he ampicillin, clindamycin, fluoroquinolones, a me cephalosporins.

Hiki i nā mea lawelawe olakino i ka haukapila ke hele i kēia bacteria mai kekahi kanaka a i kekahi.

ʻO ka colitis Pseudomembranous ka mea maʻamau ʻole i nā keiki, a kākaʻikahi i nā pēpē. ʻIke pinepine ʻia i ka poʻe i ka haukapila. Eia nō naʻe, ke lilo nei i mea maʻamau i ka poʻe e lawe i nā lāʻau ʻaloʻalo a ʻaʻohe ma ka haukapila.

ʻO nā kumu pilikia me:

• Makahiki
• Hoʻohana Antibiotic
• Hoʻohana o nā lāʻau e hoʻonāwaliwali i ka ʻōnaehana pale (e like me nā lāʻau chemotherapy)
• ʻOki kino hou
• Mōʻaukala o colse pseudomembranous
• Mōʻaukala o ka ulcerative colitis a me ka maʻi Crohn

ʻO nā hōʻailona me:

• ʻO nā ʻōpū ʻōpū (ʻoluʻolu a koʻikoʻi)
• Nā noho koko
• Fiva
• Koi aku i kahi ʻōpū
• ʻO ka diarrhea wai (pinepine 5 a 10 mau manawa i kēlā me kēia lā)

E hana ʻia paha kēia mau hoʻāʻo:

• ʻO Colonoscopy a i ʻole sigmoidoscopy maʻalahi
• Immunoassay no C difficile toxin i ka noho
• ʻO nā hoʻāʻo hou hou aʻe e like me PCR

ʻO ka lāʻau antibiotic a i ʻole nā ​​lāʻau ʻē aʻe e hōʻoki ana i ke ʻano. Hoʻohana pinepine ʻia ka Metronidazole, vancomycin, a i ʻole fidaxomicin e mālama i ka pilikia, akā hoʻohana ʻia paha nā lāʻau ʻē aʻe.

Pono paha nā hopena electrolyte a i ʻole nā ​​wai i hāʻawi ʻia ma o ka aa e mālama ai i ka make wai ma muli o ka palahī. I nā kūlana kakaʻikahi, pono ke kīpoki e mālama i nā maʻi iʻoi aku ka maikaʻi ʻole a pane ʻole paha i nā lāʻau ʻino.

Pono paha nā antibiotic lōʻihi inā makemake ka C difficile hoʻi ka maʻi. Ua mālama ʻia kahi lapaʻau hou i kapa ʻia ʻo fecal microbiota transplant ("stool transplant") no nā maʻi i hoʻi mai.

E ʻōlelo paha kāu mea hāʻawi aku iā ʻoe e lawe i nā probiotics inā hoʻi ka maʻi.

Maikaʻi ka nānā i ka hapanui o nā hihia, inā ʻaʻohe pilikia. Eia nō naʻe, hiki i ka 1 i loko o 5 mau maʻi ke hoʻi a pono hou i ka lāʻau.

Komo pū nā pilikia:

• Ka make wai ʻana me ke kaulike ʻole electrolyte
• Perforation of (hole through) ke kolona
• Mekacolon ʻona
• Make

Kāhea i kāu mea hāʻawi inā loaʻa iā ʻoe kēia mau ʻōuli:

• ʻO nā noho koko (ʻoiai ma hope o ka lawe ʻana i nā lāʻau ʻaloʻalo)
• ʻElima a ʻoi paha ʻāpana o ka maʻi diarrhea i kēlā me kēia lā no ka ʻoi aku o 1 a 2 mau lā
• ʻEha ʻeha loa
• Nā hōʻailona o ka make wai

ʻO ka poʻe i loaʻa i ka colitis pseudomembranous pono e haʻi i kā lākou mea hāʻawi ma mua o ka lawe hou ʻana i nā lāʻau ʻaloʻalo. He mea nui nō hoʻi e holoi maikaʻi i nā lima e pale ai i ka hāʻawi ʻana i ka germ i kekahi poʻe ʻē aʻe. ʻAʻole holo mau nā mea hoʻomaʻemaʻe ʻalekoke C difficile.

Colitis pili i ka Antibiotic; Colitis - pseudomembranous; Necrotizing colitis; C difficile - pseudomembranous

• ʻŌnaehana Digestive
• Nā ʻōnaehana ʻōnaehana Digestive

ʻO Gerding DN, Johnson S. Clostridial maʻi. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil. 26th ed. Piladelapia, PA: Elsevier; 2020: chap 280.

ʻO Gerding DN, VB ʻōpio. ʻO Donskey CJ. ʻO difficile Clostridiodes (ma mua ʻO Clictridium difficle) maʻi maʻi. I: Bennett JE, Dolin R, Blaser MJ, hua pā. ʻO Mandell, Douglas, a me Bennett's Principle a me ka hoʻomaʻamaʻa ʻana i nā maʻi kūpilikiʻi. 9th ed. Piladelapia, PA: Elsevier; 2020: chap 243.

Kelly CP, Khanna S. Antibiotic-pili diarrhea a me difficile clostridioides maʻi maʻi. I: Feldman M, Friedman LS, Brandt LJ, eds. ʻO Sleisenger a me Fordtran's Gastrointestinal a me ka maʻi ate. 11th hua. Piladelapia, PA: Elsevier; 2021: chap 112.

McDonald LC, Gerding DN, Johnson S, et al. Nā kulekele hana lapaʻau no ka maʻi clostridium difficile i nā mākua a me nā keiki: 2017 hōʻano e ka Infectious Diseases Society of America (IDSA) a me ka Society for Healthcare Epidemiology of America (SHEA). Maʻi maʻi maʻi Dis. 2018; 66 (7): 987-994. PMID: 29562266 pubmed.ncbi.nlm.nih.gov/29562266/.