VIPoma

ʻO VIPoma kahi maʻi ʻaʻai liʻiliʻi laha ʻole e ulu maʻamau mai nā hunaola i nā pancreas i kapa ʻia he mau ʻāpana islet.

Hoʻokumu ʻo VIPoma i nā hunaola i ka pancreas e hana i kahi pae kiʻekiʻe o kahi hormone i kapa ʻia ʻo vasoactive usus peptide (VIP). Hoʻonui kēia hormone i nā huna mai nā ʻōpū. Hoʻomaha ia kekahi o nā mākala maʻalahi i ka ʻōnaehana gastrointestinal.

ʻAʻole ʻike ʻia ke kumu kūpono o VIPomas.

Hoʻomaopopo pinepine ʻia ʻo VIPomas i nā mākua, ʻo ka mea maʻamau ma kahi o 50 mau makahiki. ʻOi aku ka hopena o nā wahine ma mua o nā kāne. Kākaʻikahi kēia kanesa. I kēlā me kēia makahiki, ma kahi o 1 wale nō i 10 miliona mau kānaka i ʻike ʻia me kahi VIPoma.

Hiki i nā ʻōuli o VIPoma ke hoʻopili i kekahi o kēia mau mea:

• ʻEha o ka ʻōpū a me ka cramping
• Diarrhea (wai, a pinepine i ka nui)
• Make wai
• ʻO Flushing a ʻulaʻula paha o ka maka
• Hoʻopilikia ka mākala ma muli o ka haʻahaʻa o ka potassium (hypokalemia)
• Nusea
• Kaumaha emi

E hana ka mea mālama ola i kahi hoʻokolohua kino a nīnau e pili ana i kāu mōʻaukala a me nā ʻōuli.

ʻO nā hoʻāʻo e hana ʻia ana paha:

• Nā hoʻāʻo kemika koko (kumu a i ʻole panel ākea metabolic)
• CT scan o ka ʻōpū
• MRI o ka ʻōpū
• Ninaninau kino no ke kumu o ka maʻi pākī a me nā pae electrolyte
• ʻO ka pae VIP i ke koko

ʻO ka pahuhopu mua o ka mālama ʻana e hoʻoponopono i ka make wai. Hāʻawi pinepine ʻia nā Fluids ma o kahi aa (nā wai hoʻowalewale) e hoʻololi i nā wai i nalowale ma o ka palahī.

ʻO ka pahuhopu e hiki mai ana e hoʻolohi i ka diarrhea. Hiki i nā lāʻau ke kōkua i ke kaohi i ka maʻi palahō. ʻO kekahi o ia ʻano lāʻau ʻo octreotide. ʻO ia kahi ʻano i hana ʻia e kahi homone kūlohelohe e ālai i ka hana o VIP.

ʻO ka manawa kūpono loa o ka hoʻōla ʻo ke ʻoki e wehe i ka tumo. Inā ʻaʻole i pālahalaha ka tumo i nā meaola ʻē aʻe, hiki i ke kīpoki ke hoʻōla pinepine i ke ʻano.

Hiki iā ʻoe ke hoʻomāmā i ke koʻikoʻi o ka maʻi ma ke komo ʻana i kahi hui kākoʻo maʻi ʻaʻai. ʻO ke kaʻana ʻana me nā poʻe ʻē aʻe i loaʻa nā ʻike a me nā pilikia maʻamau e hiki ke kōkua iā ʻoe e noʻonoʻo ʻole.

Hiki i ke kīpoki ke hoʻōla iā VIPomas. Akā, i ka hapakolu a i ka hapalua o ka poʻe, ua pālahalaha ka ʻōpū e ka manawa o ke kuhi a ʻaʻole hiki ke hoʻōla ʻia.

Komo pū nā pilikia:

• Pāhola maʻi ʻaʻai (metastasis)
• Hopu ʻo Cardiac mai ke kiʻekiʻe o ka potassium potassium
• Make wai

Inā loaʻa ʻoe i ka maʻi pākī wai ma mua o 2 a 3 mau lā, e kāhea i kāu mea hāʻawi.

ʻO ka tumo hana hua peptide Vasoactive; Maʻi maʻi VIPoma; Tumre endocrine tumreatic

• ʻO Pancreas

Pūnaewele ʻo National Cancer Institute. ʻO nā tumere neuroendocrine Pancreatic (tumors cell tumors) lapaʻau (PDQ) - mana ʻoihana olakino. www.kanaka.gov/types/pancreatic/hp/pnet-treatment-pdq. Hoʻohou i Pepeluali 8, 2018. Loaʻa iā Nowemapa 12, 2018.

ʻO Schneider DF, Mazeh H, Lubner SJ, Jaume JC, Chen H. Cancer o ka ʻōnaehana endocrine. I: Niederhuber JE, Armitage JO, Doroshow JH, Kastan MB, Tepper JE, eds. ʻO Oncology Clinical ʻo Abboff. 5th lā. Piladelapia, PA: Elsevier Saunders; 2014: chap 71.

ʻO Vella A. Gastrointestinal hormones a me nā ʻōpū endocrine ʻōpū. I: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. ʻO Williams Textbook of Endocrinology. 13th ed. Piladelapia, PA: Elsevier; 2016: chap 38.