He aha ka thrombocythemia pono, nā ʻōuli, ka hōʻoia a pehea e mālama ai

Anter

• Nā hōʻailona nui
• ʻO ka maʻi ʻaʻai thrombositosis pono?
• Pehea e hana ʻia ai ke kuhi
• Hoʻomaʻo no ka thrombositosis pono

ʻO ka thrombocythemia nui, a ʻo TE paha, kahi maʻi hematological i hōʻike ʻia e ka hoʻonui ʻana i ka nui o nā platelet i loko o ke koko, kahi e hoʻonui ai i ka maka o ka thrombosis a me ke kahe ʻana o ke kahe.

ʻO kēia maʻi maʻamau ka asymptomat, ʻike ʻia ma hope wale nō o ka hana ʻia ʻana o kahi helu maʻamau o ke koko. Eia nō naʻe, hōʻoia wale ʻia ke kuhi e ke kauka ma hope o ke kāpae ʻana i nā kumu kūpono ʻē aʻe o ka hoʻonui ʻia o nā platelet, e like me ka anemia hemahema hao, no ka laʻana.

Hana ʻia me ka lāʻau lapaʻau me nā lāʻau i hiki ke hōʻemi i ka helu o nā platelet i loko o ke koko a hoʻemi i ka maka o ka thrombosis, a pono e hoʻohana ʻia e like me ke kuhikuhi a ka mea hana maʻamau a hematologist paha.

Nā hōʻailona nui

ʻO ka thrombositosis nui ka mea asy asymatic, ʻike ʻia ma hope wale nō o ka helu ʻana o ke koko. Eia nō naʻe, hiki ke hopena i kekahi mau ʻōuli, nā mea nui i:

• ʻO ke ahi wela i nā wāwae a me nā lima;
• Splenomegaly, ʻo ia ka hoʻonui i ka palahu;
• ʻEha o ka umauma;
• Hoʻoulu;
• Nāwaliwali;
• ʻEha poʻo poʻo;
• Makapō kuamoe, he hapa a i ʻole piha paha;
• Kaumaha emi.

Eia kekahi, ʻo ka poʻe i ʻike ʻia me ka thrombocythemia pono e hoʻonui i ka weliweli o ka thrombosis a me ke kahe ʻana o ke kahe. ʻOi aku ka maʻi o kēia maʻi i ka poʻe ma mua o 60, akā hiki nō ke hana i ka poʻe ma lalo o 40.

ʻO ka maʻi ʻaʻai thrombositosis pono?

ʻO ka thrombocythemia nui ʻaʻole ka maʻi ʻaʻai, ʻoiai ʻaʻohe ulu o nā keena ʻino, akā nā pūnaewele maʻamau, i kēia hihia, nā platelet, e hōʻike ana i ke ʻano o ka thrombositosis a i ʻole thrombositosis. Noho paʻa kēia maʻi ma kahi o 10 a 20 mau makahiki a loaʻa kahi haʻahaʻa haʻahaʻa o ka hoʻololi leukemia, ma lalo o 5%.

Pehea e hana ʻia ai ke kuhi

Hana ʻia ke kuhi e ka loio maʻamau a i ʻole hematologist e like me nā hōʻailona a me nā ʻōuli i hōʻike ʻia e ka mea hoʻomanawanui, a me nā hopena o nā hoʻokolohua hoʻokolohua. He mea nui nō hoʻi e kāpae i nā kumu ʻē aʻe o ka hoʻonui ʻia o nā platelet, e like me nā maʻi hōʻeha, myelodysplasia a me ka hemahema hao, no ka laʻana. ʻIke i nā kumu nui o ka hoʻonui platelet.

Hana ʻia ka diagnostical laboratory o thrombocythemia nui ma o ka nānā ʻana i ka helu o ke koko, kahi e ʻike ʻia ai ka hoʻonui ʻia ʻana o nā platelet, me kahi waiwai ma luna o 450,000 platelets / mm³ o ke koko. ʻO ka maʻamau, hana hou ʻia ka hoʻopili platelet i nā lā like ʻole e ʻike inā hoʻonui mau ʻia ka waiwai.

Inā hoʻomau ʻia nā platelet, hana ʻia nā hoʻokolohua kūlohelohe e nānā ai i ke kū ʻana o kahi mutation i hōʻike ʻia o thrombocythemia pono, ka JAK2 V617F hoʻololi, aia ma kahi o 50% o nā maʻi. Inā hōʻoia ʻia ke kū ʻana o kēia hoʻololi, pono pono e kāpae i ka hanana ʻana o nā maʻi ʻino ʻino a nānā i nā mālama hao mālama pono.

I kekahi mau hihia, hiki ke hoʻokō ʻia ka biopsy iwi pū, kahi e hoʻonui ʻia ai ka nui o nā megakaryocytes, ʻo ia nā aʻa koko o ka pā mua.

Hoʻomaʻo no ka thrombositosis pono

Hoʻolālā ka lapaʻau no thrombocythemia nui e hoʻemi i ka makaʻu o ka thrombosis a me ka hemorrhage, a ua ʻōlelo pinepine ʻia e ke kauka e hoʻohana i nā lāʻau e hōʻemi i ka nui o nā platelet i ke koko, e like me Anagrelide a me Hydroxyurea, no ka laʻana.

ʻO Hydroxyurea ka lāʻau i koi mau ʻia no ka poʻe i manaʻo ʻia he makaʻu nui, ʻo ia hoʻi, ʻoi aku ma mua o 60 mau makahiki, ua loaʻa kahi ʻāpana o ka thrombosis a he helu platelet ma luna o 1500000 / mm³ o ke koko. Eia nō naʻe, loaʻa i kēia lāʻau kekahi mau hopena, e like me hyperpigmentation o ka ʻili, nausea a me ka luaʻi.

ʻO ka mālama ʻana i nā mea maʻi i ʻike ʻia he haʻahaʻa haʻahaʻa, ʻo ia ka poʻe ma lalo o 40 mau makahiki, hana mau ʻia me ka acetylsalicylic acid e like me ke alakaʻi a ka mea hana maʻamau a hematologist paha.

Eia hou, e hōʻemi i ka makaʻu o ka thrombosis he mea nui e hōʻalo i ka puhipaka a mālama i nā maʻi kūlohelohe e like me ka hypertension, ka momona a me ka maʻi kō, ke hoʻonui lākou i ka maka o ka thrombosis. ʻIke i ka mea e hana ai e pale ai i ka thrombosis.