Hōʻike Cholinesterase: he aha ia, he aha ia a he aha ke ʻano o ka hopena

Anter

• No ke aha ia
• Nā manaʻo kūmole
• He aha ka manaʻo o nā hopena

ʻO ka hoʻokolohua cholinesterase kahi hoʻokolohua hoʻokolohua i noi ʻia i mea e hōʻoia ai i ke kiʻekiʻe o ka hōʻike ʻana o ke kanaka i nā huahana ʻona, e like me nā pesticides, insecticides, herbicides a i ʻole nā ​​mea momona, no ka laʻana, no laila he kūpono loa no nā mahiʻai, no ka mea pili mau lākou me nā huahana mahiʻai.

ʻO Cholinesterase kahi enzyme i loko o ke kino nona ke kuleana no ka haki ʻana o kahi mea i kapa ʻia acetylcholine, kahi neurotransmitter kuleana no ka kaohi ʻana i nā impulses nerve i nā mākala. Aia ʻelua papa o cholinesterase:

• Erythrocyte cholinesterase, lawe ʻia e nā ʻulaʻula koko;
• Plasma cholinesterase a i ʻole ka serum, ʻo ia ka cholinesterase e hana ʻia e ke ake, pancreas a me ka ʻōpū liʻiliʻi a e holo i loko o ke koko koko.

He mea nui ka nānā ʻana i nā pae cholinesterase i hiki ke ʻike koke ʻia a hoʻololi ʻia kekahi mau loli, e hōʻalo ana i nā pilikia no ke kanaka.

No ke aha ia

Paipai ʻia ka hōʻike cholinesterase e ke kauka ma ka nānā nui ʻana i ke kaʻina o ka hōʻike ʻana o nā mahiʻai, e laʻa me nā insecticides a me nā pesticides.

Hoʻohui ʻia, hiki ke noi ʻia ke ana o kēia enzyme e nānā i nā mea maʻi me ka maʻi akepau, keu hoʻi i ka poʻe i hana i ke ake o ke ake, no ka mea ua hoʻemi lākou i nā pae cholinesterase.

Hiki ke hōʻike ʻia ke ana o cholinesterase no ka poʻe i loaʻa ka hoʻololi e hoʻopilikia i ka hana pololei a i ʻole ka hana ʻana o kēia enzyme.

Nā manaʻo kūmole

Hoʻololi nā kumukūʻai kūmole Cholinesterase e like me ka keʻena hoʻokolohua a me ka pahu i hoʻohana ai e hana i ka hōʻike. No laila, hiki i nā helu kūmole maʻamau ma waena o:

• Men: 4620 - 11500 U / L
• Nā wahine: 3930 - 10800 U / L

Hana ʻia kēia hōʻike e like me nā hōʻike koko ʻē aʻe, ʻo ia hoʻi, hōʻiliʻili ʻia kahi laʻana koko liʻiliʻi a hoʻouna ʻia i ka hale hana e nānā ʻia e ka lālā biokimia. Wahi a ka keʻena hoʻokolohua e koi ʻia e hoʻokē ʻai no 4 mau hola.

He aha ka manaʻo o nā hopena

ʻO ʻoe pae haʻahaʻa o cholinesterase kuhikuhi nui i ka hoʻolōʻihi ʻia ʻana i nā pesticides organophosphate, ʻo ia nā mea i loaʻa i nā insecticides, pesticides a me nā herbicides hiki ke kāohi i ka hana o kēia enzyme, e alakaʻi ana i ka hōʻiliʻili o acetylcholine a i hopena i ka hiʻona o kekahi mau hōʻailona a me nā ʻōuli, e like me :

• Pākuʻi;
• Pohā;
• ʻO ka luaʻi;
• Nui loa i ka salivation;
• Pilikia ʻike maka;
• Hoemi i ke kahe o ke koko;
• Nāwaliwali o ka ʻiʻo;
• Pālolo.

ʻOiai ʻo ka emi ʻana o nā pae cholinesterase e pili nui i ka ʻona ʻana, aia paha kekahi e hoʻoliʻiliʻi i kēia enzyme i ka hihia o ka maʻi hepatitis, cirrhosis, puʻuwai puʻuwai congestive, maʻi ʻaʻai nui a infarction.

No laila, he mea nui e wehewehe ʻia nā hopena o ka hoʻokolohua cholinesterase me nā hopena o nā hoʻokolohua ʻē aʻe i ʻike ʻia ke kumu o ka hōʻemi ʻana o kēia enzyme a hiki ke hōʻike ʻia ka lapaʻau kūpono.

Ma ka lima 'ē aʻe, pae kiʻekiʻe ʻo cholinesterase, hana maʻamau ma muli o ka momona, diabetes, nephrotic syndrome a me hyperthyroidism.