Mea Kākau: Eugene Taylor
Lā O Ka Hana: 16 Aukake 2021
HōʻAno Hou I Ka Lā: 20 Kepakemapa 2024
Anonim
How to Inject Taltz
Wikiō: How to Inject Taltz

Anter

He aha ʻo Taltz?

ʻO Taltz kahi lāʻau lapaʻau inoa inoa inoa inoa inoa. Ua ʻae ʻia e mālama i nā kūlana aʻe:

No ka plaque psoriasis, hiki ke kuhikuhi ʻia ʻo Taltz no nā mākua a me nā keiki o nā makahiki 6 a ʻoi paha. Akā no nā hoʻohana ʻē aʻe i ʻae ʻia, hiki ke kuhikuhi ʻia ʻo Taltz no nā mākua.


Aia ʻo Taltz i ka lāʻau i hana i ka wahine ʻo wau. He ʻano lāʻau biologic (kahi lāʻau i hana ʻia mai nā pūnaewele ola) i kapa ʻia he antibody monoclonal humanized.

Hele mai ʻo Taltz i ʻelua ʻano: he syringe i hoʻomākaukau ʻia a me kahi peni autoinjector prefilled. Hāʻawi ʻia ka lāʻau lapaʻau e ka pahu kui ma lalo o kou ʻili (subcutaneous injection). E hāʻawi aku kāu kauka olakino iā ʻoe i ka injection i ka mua. A laila hiki iā lākou ke aʻo iā ʻoe pehea e hāʻawi ai i ka injection iā ʻoe iho ma ka home.

Ka hoʻokō ʻana

No ka ʻike e pili ana i ka maikaʻi o Taltz i ka mālama ʻana i nā kūlana i helu ʻia ma luna, e ʻike i ka ʻāpana "Taltz hoʻohana" ma lalo.

ʻO Taltz generic

Loaʻa ʻo Taltz ma ke ʻano he lāʻau lapaʻau inoa. ʻAʻole i loaʻa i kēia manawa i kahi ʻano laulā. (ʻO kahi lāʻau laulā kahi kope pololei o ka lāʻau lapaʻau hana i kahi lāʻau lapaʻau inoa.)

Loaʻa iā Taltz hoʻokahi mea hana lāʻau lapaʻau: ixekizumab.

ʻO Taltz lāʻau kō

ʻO ka mahele lāʻau Taltz a ke kauka i kuhikuhi ai i ka ʻano o ka mālama ʻia.

Hōʻike ka ʻikepili aʻe i nā lāʻau i hoʻohana pinepine ʻia a koi ʻia paha. Eia nō naʻe, e noʻonoʻo pono e lawe i nā mea hana a hāhai i ka papa kuhikuhi dosing a kāu kauka e kuhikuhi ai nāu.


Nā ʻano lāʻau a me nā ikaika

Loaʻa ʻo Taltz i hoʻokahi ikaika: 80 milligrams i kēlā me kēia milliliter (mg / mL).

Hele mai ka lāʻau i loko o nā ʻano: he syringe prefilled hoʻohana hoʻokahi a me kahi peni autoinjector prefilled hoʻohana hoʻokahi. Hiki paha iā ʻoe ke ʻike he maʻalahi kahi ʻano na ʻoe e hoʻohana ma mua o kekahi. E kamaʻilio me kāu kauka e pili ana i kahi palapala e pono ai nāu.

Hāʻawi ʻia ka lāʻau lapaʻau e ka pahu kui ma lalo o kou ʻili (subcutaneous injection). E hāʻawi aku kāu kauka olakino iā ʻoe i ka injection i ka mua. A laila hiki iā lākou ke aʻo iā ʻoe pehea e hāʻawi ai i ka injection iā ʻoe iho ma ka home.

Nā hana no ka psoriatic arthritis

No ka psoriatic arthritis, e hāʻawi ʻia kāu mahele lāʻau Taltz i ʻelua inikina 80-mg (no ka nui o 160 mg) i ka lā like. Ma hope o kēlā, ʻo kāu mea mālama mālama kahi 80-mg injection i hoʻokahi manawa i kēlā me kēia 4 mau pule no ka lōʻihi o ke kauka.

Kaha: E aʻo hou aʻe e pili ana i ka psoriatic arthritis, e ʻike i ka ʻāpana "Taltz hoʻohana" ma lalo.

Nā hana no ka mea he kaulike a koʻikoʻi psoriasis plake

No ka plaque psoriasis, ʻo kāu mahele lāʻau Taltz ʻelua mau inikina he 80-mg (no ka huina o 160 mg) i ka lā like. Ma hope o kēlā, loaʻa iā ʻoe kahi injection 80-mg i hoʻokahi manawa i kēlā me kēia 2 pule no 12 mau pule. A laila ʻo kāu mālama ʻana e lilo i hoʻokahi inika hoʻokahi i kēlā me kēia 4 pule no ka lōʻihi o ke kauka.


Kaha: E aʻo hou aʻe e pili ana i ka plake psoriasis, e ʻike i ka ʻāpana ʻo "Taltz hoʻohana" ma lalo.

Nā hana no ka psoriatic arthritis a me ka kaulike a hiki i ka plake koʻikoʻi psoriasis

Inā loaʻa iā ʻoe ka maʻi psoriatic psoriatic a me ka plaque psoriasis, e hoʻohana ʻoe i ke ana ʻo Taltz a me ka papa kuhikuhi dosing no ka mea he kaulike a ʻoi loa ka plake psoriasis. E ʻike i ka ʻāpana ma luna wale nō no ka ʻike e pili ana i kēia.

Kaha: E aʻo hou aʻe e pili ana i ka psoriatic arthritis a me ka plaque psoriasis, e ʻike i ka mahele ʻo "Taltz hoʻohana" ma lalo.

Nā hana no ka spondyloarthritis axial axial ʻole radiographic

No ka radiondial axial spondyloarthritis (nr-axSpA), e loaʻa iā ʻoe kahi ʻāpana 80-mg o Taltz i hoʻokahi manawa i kēlā me kēia 4 pule.

Kaha: E aʻo hou aʻe e pili ana i nr-axSpA, e ʻike i ka ʻāpana "Taltz hoʻohana" ma lalo.

Nā hana no ka spondylitis ʻeleu e hana ana

No ka ankylosing spondylitis (AS), ʻo kāu mahele lāʻau Taltz mua he ʻelua iniha 80-mg (no ka huina o 160 mg) i ka lā like. Ma hope o kēlā, ʻo kāu mea mālama mālama kahi 80-mg injection i hoʻokahi manawa i kēlā me kēia 4 pule.

Kaha: E aʻo hou aʻe e pili ana iā AS, e ʻike i ka ʻāpana ʻo "Taltz hoʻohana" ma lalo.

He aha inā e haʻo wau i kahi lāʻau?

Inā ʻoe e nalo i kahi injection, pono ʻoe e loaʻa iā ia i ka manawa hiki. A laila e lawe wale i kāu injection hou ke hiki ke kūpono. Akā inā ʻoe e nalo i kahi injection a ʻaʻole lōʻihi ia a hiki i ka hopena o kāu mea aʻe, e noi i kāu kauka no ka ʻōlelo aʻo e pili ana i ka mea e hana ai.

I mea e ʻike pono ai ʻaʻole ʻoe e haʻalele i kahi lāʻau, e hoʻāʻo e kau i kahi hoʻomanaʻo ma kāu kelepona. He mea pono nō hoʻi ka wati lāʻau.

Pono wau e hoʻohana i kēia lāʻau lōʻihi?

Hoʻohana ʻia ʻo Taltz e like me kahi lapaʻau lōʻihi. Inā hoʻoholo ʻoe a me kāu kauka e hana maikaʻi ʻo Taltz iā ʻoe, malia paha e hoʻomau ʻoe i ka hoʻohana ʻana ia mea ma kahi wā lōʻihi.

Nā hopena ʻino ʻo Taltz

Hiki iā Taltz ke hana i nā hopena ʻoluʻolu a koʻikoʻi paha. Loaʻa i nā papa inoa aʻe kekahi o nā hopena ʻaoʻao nui i hiki ke hana ʻia i ka lawe ʻana iā Taltz. ʻAʻole pili kēia papa inoa i nā hopena ʻaoʻao āpau.

No ka ʻike hou aku e pili ana i nā hopena ʻē aʻe o Taltz, e kamaʻilio me kāu kauka a kauka paha. Hiki iā lākou ke hāʻawi iā ʻoe i nā ʻōlelo aʻoaʻo e pili ana i ka hana me nā hopena ʻē aʻe e hoʻonāukiuki paha.

Kaha: Mālama ka Food and Drug Administration (FDA) i nā hopena o nā lāʻau i ʻae ʻia. Inā makemake ʻoe e hōʻike i ka FDA i kahi hopena i loaʻa iā ʻoe me Taltz, hiki iā ʻoe ke hana pēlā ma o MedWatch.

Nā hopena ʻaoʻao hou aʻe

Hiki i nā hopena ʻaoʻao maʻamau o Taltz ke hoʻopili pū:

  • nā hopena o ka pūnaewele injection (ʻulaʻula a me ka ʻeha a puni ka ʻāpana ʻāluna
  • nā maʻi hanu o luna, e like me ke anuanu maʻamau a i ʻole ka maʻi flu
  • nausea
  • nā maʻi fungal, e like me ka wāwae o ka ʻālapa
  • conjunctivitis (maka poni)

E hala paha ka hapa nui o kēia mau hopena i loko o kekahi mau lā a i ʻole ʻelua mau pule. Inā ʻoi aku ke koʻikoʻi a i ʻole hele aku, e kamaʻilio me kāu kauka a kauka paha.

Nā hopena hopena koʻikoʻi

ʻAʻole maʻamau nā hopena koʻikoʻi mai Taltz, akā hiki iā lākou ke hana. Kāhea koke i kāu kauka inā loaʻa nā hopena koʻikoʻi. Kāhea iā 911 inā manaʻo kou mau ʻōuli i ka hoʻoweliweli o ke ola a i ʻole inā manaʻo ʻoe e loaʻa ana kahi pilikia olakino.

Nā hopena ʻino, i wehewehe ʻia ma ke kikoʻī ma lalo o ka "ʻaoʻao ʻaoʻao kikoʻī," e hoʻopili pū me:

  • nā hopena maʻi ʻino nui
  • ʻo ka maʻi ʻōpū (IBD), e like me ka maʻi o Crohn a i ʻole colitis ulcerative
  • hoʻonui i ka makaʻu o nā maʻi, e like me ka maʻi kō (TB)

Nā hopena ʻē aʻe i nā keiki

Ua nānā ʻia kahi noiʻi hoʻokolohua i nā keiki mai nā makahiki 6 a 18 mau makahiki i loaʻa ka maʻi maʻi plaque. I kēia noi ʻana, ʻo nā ʻano o nā hopena i ʻike ʻia i nā keiki a me nā manawa pinepine e like ai me nā mea i ʻike ʻia i nā mākua. Ma kahi ʻokoʻa i kēia, ua hopena pinepine nā hopena ʻē aʻe i nā keiki ma mua o nā mākua.

  • conjunctivitis (maka poni)
  • ka maʻi palū
  • hives (kahi ʻili ʻili ʻili)

I ke aʻo like, ua kū ka maʻi o Crohn i ka 0.9% pinepine i nā keiki e lawe nei iā Taltz ma mua o ka hana ʻana i nā keiki i kahi placebo. (ʻO kahi placebo kahi lapaʻau me ka lāʻau ʻole.)

Nā kikoʻī hopena ʻaoʻao

E noʻonoʻo paha ʻoe i ka pinepine o kekahi mau hopena i hopena ʻia me kēia lāʻau, a i ʻole pili kekahi mau ʻaoʻao iā ia. Eia kekahi mau kikoʻī e pili ana i kekahi o nā hopena i hiki ʻole ai i kēia lāʻau.

Ka hopena hoʻowali

E like me ka nui o nā lāʻau, hiki i kekahi poʻe ke loaʻa i kahi hopena maʻi ma hope o ka lawe ʻana iā Taltz. Hiki i nā ʻōuli o ke ʻano ʻāpiki mālie ke hoʻopili pū i:

  • ʻāwīwī o ka ʻili
  • ʻumeʻume
  • flushing (hoʻomehana a ʻulaʻula i kou ʻili)

Kākaʻikahi ka hopena maʻi ʻino ʻoi aku ka paʻakikī akā hiki. Hiki i nā ʻōuli o ke kūpilikiʻi ʻāpiki loa ke hoʻopili pū me

  • angioedema (ʻōhū ma lalo o kou ʻili, maʻamau i kou mau lihilihi, nā lehelehe, a me nā papalina)
  • pehu o kou alelo, waha, a ʻāʻī paha
  • pilikia hanu
  • paʻa paʻa o ka umauma
  • e maule ana

I nā noiʻi hoʻokolohua, ua hana nā hopena maʻi maʻi i ka 0,1% a ʻoi aku paha o ka poʻe i loaʻa iā Taltz. ʻO kēia mau hopena maʻi ʻaʻaied angioedema a me urticaria (kahi ʻili ʻili ʻili i ʻike ʻia ʻo nā hives).

Kāhea koke i kāu kauka inā loaʻa iā ʻoe kahi maʻi maʻi ʻino loa iā Taltz. Akā e kāhea iā 911 a i kāu helu kūloko kūloko inā manaʻo kou mau ʻōuli ke hoʻoweliweli i ke ola a i ʻole inā manaʻo ʻoe e loaʻa ana kahi pilikia olakino.

ʻO ka hopena o ka pūnaewele injection

Loaʻa paha iā ʻoe kahi hopena o ka ʻili ma kahi āu e hoʻopili ai i nā lāʻau o Taltz. A hana paha kēia mau hopena i nā ʻōuli e like me ka ʻulaʻula a i ʻole ʻeha.

I nā noiʻi hoʻokolohua, 17% o ka poʻe me ka plake psoriasis i loaʻa iā Taltz i loaʻa i kahi hopena, e like me ka ʻulaʻula a i ʻole ka ʻeha, ma ka pūnaewele injection. ʻO ka hapa nui o kēia mau hopena he akahai a akahai paha a ʻaʻole i hoʻokau i ka poʻe e hōʻoki i ka lāʻau.

I kēlā me kēia manawa e hoʻokomo ʻoe iā Taltz, pono ʻoe e koho i kahi kiko ʻē aʻe i kou kino ma mua o ka ʻoki hope loa. Inā loaʻa iā ʻoe ka hopena o ka ʻili i koʻikoʻi a ʻaʻole hele aku i kekahi mau lā, e ʻike i kāu kauka.

Hoʻonui i ka pilikia o nā maʻi

Hiki iā Taltz ke hoʻonāwaliwali i kāu ʻōnaehana pale. Ke lawa ʻole ka ikaika o kāu ʻōnaehana pale pale e pale aku ai i nā germat, hiki paha iā ʻoe ke loaʻa i kahi maʻi.

I nā noiʻi hoʻokolohua, 27% o ka poʻe me ka pālolo psace i loaʻa iā Taltz no 12 mau pule i loaʻa i ka maʻi. Eia kekahi o nā noiʻi i loaʻa:

  • ʻO ka hapa nui o kēia mau maʻi he akahai. ʻO 0.4% wale nō o nā maʻi i manaʻo ʻia he koʻikoʻi, e like me ka niumonia.
  • ʻO nā maʻi maʻa mau nā maʻi hanu e like me nā anu, nā anu, a me nā maʻi puʻu.
  • ʻO nā maʻi ʻē aʻe i hoʻopili ʻia me ka conjunctivitis (maka ʻākala) a me nā maʻi fungal, e like me ka thrush waha a me ka wāwae o ka ʻaleʻale.
  • I loko o kēia mau noiʻi, 23% o ka poʻe i loaʻa kahi placebo (lapaʻau me ka hoʻohana ʻole ʻana o ka lāʻau) i loaʻa i kahi maʻi.
  • I ka poʻe i loaʻa iā Taltz lapaʻau no 60 mau pule, 57% ka maʻi i hoʻohālikelike ʻia me 32% i loaʻa kahi placebo.

Ka nānā ʻana a me ka nānā ʻana i nā maʻi

Inā loaʻa iā ʻoe nā ʻōuli o kahi maʻi, e kamaʻilio me kāu kauka a kauka paha. Hiki iā lākou ke paipai i ka lāʻau. Pākuʻi ʻia paha nā ʻōuli o nā maʻi liʻiliʻi:

  • fiva
  • ʻūhā
  • eha ka 'ā'ī
  • ʻulaʻula a ʻeha nā maka
  • ʻulaʻula a ʻeha nā wahi o ka ʻili
  • ʻāpana keʻokeʻo i kou waha
  • ʻāʻā a ʻeha paha i ka wā e mimi ai

He mea nui loa ia e ʻike i kāu kauka inā ʻaʻole maopopo ka maʻi. Inā ʻole, hiki ke lilo i koʻikoʻi.

Ma mua o kou hoʻomaka ʻana i ka lāʻau hoʻomalu me Taltz, e nānā kāu kauka no nā maʻi āpau, e like me ka maʻi pākī (TB), kahi maʻi lolo. Inā loaʻa iā ʻoe kekahi hōʻailona o ka TB i kou wā o ka mālama ʻana, he mea nui e kāhea koke aku i kāu kauka. Loaʻa kēia mau ʻōuli:

  • fiva
  • ʻeha ka ʻili
  • ke kaupaona ʻana me ka hoʻāʻo ʻole
  • he puʻu ʻinoʻino e mau ana no 3 mau pule a ʻoi paha
  • e ʻū ana i ke koko a i ʻole ka mucus
  • ʻeha ma ka umauma
  • puhū pō

Ke pale nei i nā maʻi i ka wā o ka mālama ʻana iā Taltz

I mea e hōʻalo ai i ka loaʻa ʻana o kahi maʻi i ka wā e lawe ana iā Taltz, holoi pinepine i kou mau lima. Eia nō hoʻi, e hōʻalo i ka pili pili loa me nā poʻe i loaʻa i ka maʻi (ʻoi aku i nā ʻū, nā anu, a me ka maʻi flu).

A e nīnau i kāu kauka inā aia kekahi lāʻau āpau e loaʻa iā ʻoe ma mua o kou hoʻomaka ʻana e lawe iā Taltz. (E ʻike iā "Taltz a me nā lāʻau ola" i ka ʻāpana "Taltz interactions" ma lalo e aʻo hou ai.)

Maʻi maʻi ʻōpū

Inā lawe ʻoe iā Taltz, aia kahi liʻiliʻi liʻiliʻi e hoʻomohala ʻoe i ka maʻi ʻōpū o ka maʻi (IBD). ʻO ka IBD kahi hui o nā maʻi e hoʻonāukiuki (pehu) i kāu wahi digestive. Hoʻopili kēia mau maʻi i ka maʻi o Crohn a me ka ulcerative colitis.

Inā loaʻa iā ʻoe ka IBD, hiki iā Taltz ke hōʻeha iā ia, akā he kakaikahi kēia. I nā noiʻi hoʻokolohua, ua loaʻa ka maʻi o Crohn i 0,1% o ka poʻe i loaʻa iā Taltz. A he 0.2% o ka poʻe i loaʻa iā Taltz ka colitis ulcerative hou a i ʻole ke ʻino paha.

Pono ʻoe e ʻike i kāu kauka inā loaʻa iā ʻoe nā hōʻailona hou a i ʻole worsening o IBD. Hiki i kēia mau mea ke:

  • ʻeha ma kou ʻōpū (ʻōpū)
  • diarrhea, me a i ʻole koko
  • Kaumaha emi

Loaʻa kaupaona a hōʻemi kino paha (ʻaʻole kahi hopena)

ʻAʻole i hōʻike ʻia ka loaʻa ʻana o ke kaupaona a me ka pohō kaumaha i nā noiʻi maʻi o Taltz. Eia nō naʻe, hiki i ka hōʻemi kaumaha ke lilo i hōʻailona o ka maʻi kō (TB) a i ʻole ka maʻi ʻōpū o ka maʻi (IBD). A ʻo kēia mau kūlana he hopena ʻelua paha ia o Taltz. No laila inā ʻoe e lilo i ka kaumaha i ka wā e lawe ana iā Taltz, he mea nui ia e ʻike i kāu kauka.

Inā he hopohopo kāu e pili ana i ka loaʻa ʻana o ke kaumaha a me ka pohō kaumaha, e kamaʻilio me kāu kauka.

Lilo ka lauoho (ʻaʻole kahi hopena)

ʻAʻole i ʻike ʻia ka nalo ʻana o ka lauoho i nā noiʻi olakino o Taltz. Eia nō naʻe, hiki i ka nalo ʻana o ka lauoho ke hopena o ka maʻi poʻo ʻoi loa, kahi ʻano o ka plaque psoriasis e hiki ke mālama ʻia me Taltz. I ka wili ʻana i kou poʻo a ʻoki paha i nā unahi, e huki paha ʻoe i kou lauoho.

Inā hopohopo ʻoe i ka nalo ʻana o ka lauoho, e kamaʻilio me kāu kauka.

Kaumaha (ʻaʻole kahi hopena)

ʻAʻole i hōʻike ʻia ke kaumaha loa ma ke ʻano he hopena ʻaoʻao i nā noiʻi maʻi o Taltz. Eia nō naʻe, maʻa mau ke kaumaha i nā poʻe me ka psoriasis a i ʻole ka psoriatic arthritis, kahi a Taltz e hoʻohana ai e mālama.

Nānā hoʻokahi kahi noiʻi e pili ana i ka hopena o Taltz i nā ʻōuli o ke kaumaha i ka poʻe me psoriasis. Ua ʻike nā kānaka noiʻi ma kahi o 40% o ka poʻe i loaʻa iā Taltz no 12 mau pule i loaʻa hou mai ko lākou mau manaʻo kaumaha.

Hiki i nā maʻi ʻili e like me psoriasis ke loaʻa i kahi hopena psychological koʻikoʻi. Inā ʻoe e kaumaha, kaumaha, a hopohopo paha, e kamaʻilio me kāu kauka e pili ana. I kekahi manawa hiki ke kōkua i ke kūkākūkā ʻana i kāu mau hopohopo. Akā inā manaʻo kāu kauka ke ʻike nei ʻoe i ke kaumaha, pono ʻoe i ka lāʻau no ia. Hiki i kēia ke hele mai i ke ʻano o ka psychological therapy a i ʻole ka lāʻau.

Huehue (ʻaʻole kahi hopena)

ʻAʻole i hōʻike ʻia ka huehue ma ke ʻano he hopena ʻaoʻao i ka noiʻi olakino ʻana o Taltz. Eia nō naʻe, ma hope o ka ʻāpono ʻia o Taltz, ua hōʻike iki kekahi poʻe i ka [KD1] [AK2] he huehue a he puʻupuʻu paha o ka ʻili. Akā he kakaikahi kēia mau hihia, a ʻaʻole maopopo inā ʻo Taltz ke kumu o ka huehue.

Hoʻohana ʻia nā lāʻau ʻo Psoriasis i kekahi manawa e mālama i kahi ʻano huehue koʻikoʻi, i kapa ʻia ʻo acne inversa (a i ʻole hidradenitis suppurativa). ʻO ia no ka mea ʻo ka huehue inversa e pili ana i ka ʻeha ʻeha, pehu, e like me ka psoriasis.

Akā ʻaʻole i aʻo ʻia ʻo Taltz no ka poʻe me kekahi ʻano huehue. I kēia manawa, ʻo ka lāʻau wale nō i ʻae ʻia e mālama i ka huehue inversa ʻo Humira (adalimumab).

Inā pili ʻoe i ka huehue, e kamaʻilio me kāu kauka. Hiki iā lākou ke hōʻike i nā ala e kōkua ai e mālama iā ia.

Kumukūʻai ʻo Taltz

E like me nā lāʻau āpau, hiki ke hoʻololi ke kumukūʻai o Taltz. No ka loaʻa ʻana o nā kumukūʻai o Taltz i kāu wahi, e nānā iā WellRx.com. ʻO ke kumukūʻai āu e ʻike ai ma WellRx.com ka mea āu e uku ai me ka ʻole o ka ʻinikua. ʻO ke kumukūʻai maoli āu e uku ai ma muli o kāu hoʻolālā ʻinikua, kou wahi, a me ka lāʻau kūʻai āu e hoʻohana ai.

Kōkua kālā a me nā ʻinikua

Inā makemake ʻoe i kākoʻo kālā e uku no Taltz, a i ʻole inā ʻoe e kōkua i ka hoʻomaopopo ʻana i kāu ʻinikua uhi, loaʻa ke kōkua.

Hāʻawi ʻo Eli Lilly a me Company, ka mea hana a Taltz, i kahi kāleka mālama kālā a me kahi papahana kākoʻo i kapa ʻia ʻo Taltz Together. No ka ʻike hou aku a e ʻike inā ua kūpono ʻoe no ke kōkua, kāhea iā 844-825-8966 a i ʻole kipa i ka pūnaewele pūnaewele.

Hoʻohana ʻo Taltz

Ua ʻae ka Food and Drug Administration (FDA) i nā lāʻau i kuhikuhi ʻia e like me Taltz e mālama i kekahi mau ʻano. Hiki ke hoʻohana ʻia ʻo Taltz i ka lepili inoa no nā kūlana ʻē aʻe. ʻO ka hoʻohana inoa inoa ʻole ke hoʻohana ʻia kahi lāʻau i ʻae ʻia e mālama i hoʻokahi kūlana e mālama ai i kahi ʻano ʻokoʻa.

ʻO Taltz no ka psoriatic arthritis

Ua ʻae ʻia ʻo Taltz e mālama i ka psoriatic arthritis ʻeleu i nā mākua.

ʻO ka psoriatic arthritis kahi ʻano o ka arthritis kahi e pehu ai, ʻeha, a paʻakikī hoʻi kekahi o nā hono. Hoʻolālā ke ʻano ma kahi o 30% o ka poʻe i loaʻa ka psoriasis. Hiki nō hoʻi ke hoʻomohala i ka psoriatic arthritis ma mua o ka loaʻa ʻana o ka psoriasis ma kou ʻili.

Hoʻopili pinepine ka psoriatic arthritis i nā hono i kāu:

  • manamana lima
  • manamana wāwae
  • nā kuli
  • kuʻekuʻe wāwae
  • nā kūpeʻe lima
  • kua malalo

Hoʻoemi ʻo Taltz i ka mumū (pehu) a me ka ʻeha o kou mau ami. Hoʻomaʻalahi paha ka lāʻau iā ʻoe e neʻe a hana i nā hana o kēlā me kēia lā, e like me ka lole, holoi, ʻai ʻana, a me ka hele wāwae.

Ka hopena no ka psoriatic arthritis

Nānā nā noiʻi maʻi i ka hopena o Taltz i nā ʻōuli o psoriatic arthritis. Ua hoʻomaopopo nā kānaka noiʻi i ka nui o ka ʻeha a ka poʻe i hōʻike ai a me ka maikaʻi o kā lākou hoʻopau ʻana i nā hana o kēlā me kēia lā. Ua hoʻokolokolo nā kānaka noiʻi i ka nui o nā hono o ka poʻe i palupalu a pehu paha.

Ma hope o 24 mau pule, hoʻomaikaʻi ʻo Taltz i kēia mau hōʻailona e:

  • ma ka liʻiliʻi 20% ma 53% a 58% o ka poʻe
  • ma ka liʻiliʻi 50% i 35% a 40% o nā kānaka
  • ma ka liʻiliʻi 70% ma 22% a 23% o ka poʻe

ʻO Taltz no ka maʻi kaulike a koʻikoʻi psoriasis

Ua ʻae ʻia ʻo Taltz e mālama i ka psoriasis kaulike i ka plaque i nā mākua a me nā keiki o nā makahiki 6 a ʻoi paha. Kūpono ia no ka poʻe nona ka psoriasis e keu pono mai ka ʻōnaehana ʻōnaehana (therapy e hoʻopili i kou kino holoʻokoʻa) a i ʻole phototherapy (hoʻomālamalama māmā).

ʻO ka plaque psoriasis ke ʻano maʻamau o ka psoriasis. Hiki iā ia ke pae mai waena a maʻalahi. Hiki i kāu kauka ke haʻi iā ʻoe i ke koʻikoʻi o kāu psoriasis a inā ʻo Taltz kūpono iā ʻoe. Kūpono paha kāu psoriasis no ka mālama ʻana me Taltz inā:

  • Loaʻa iā ʻoe nā pāka (mānoanoa, ʻulaʻula, pākuʻi scaly) ma mua o 3% o kou kino
  • he pākaukau kou ma kou mau lima, ka wāwae, a me nā genital
  • pili nui kāu psoriasis i kou ʻano o ke ola
  • nā mālama ʻana i kumuhana (hoʻopili ʻia i kou ʻili) ʻaʻole i lawe ʻia kāu psoriasis

Kōkua ʻo Taltz i ka hoʻēmi ʻana i ka helu o nā plake psoriasis a me ka nui o ia mau mea.

Ka hopena no ka plake psoriasis i nā mākua

Nānā nā noiʻi hoʻokolohua pehea i loli ai ʻo Taltz i nā ʻōuli o ka plake psoriasis i nā mākua o nā makahiki 18 a ʻoi. Ma hope o 12 mau pule, ua hoʻomaha ʻo Taltz i nā ʻōuli e:

  • ma ka liʻiliʻi 75% ma 87% a 90% o ka poʻe
  • ma ka liʻiliʻi 90% i 68% i 71% o ka poʻe
  • 100% i 35% a 40% o nā kānaka

Nānā pū kekahi nā kānaka noiʻi i ka maikaʻi o ka hana ʻana a Taltz i ka poʻe i hoʻomaʻemaʻe ʻia nā ʻōuli o ka psoriasis, a ua liʻiliʻi paha, ma hope o 12 mau pule o ka lapaʻau Ma hope o 60 mau pule o ka lawe ʻana iā Taltz, 75% o kēia mau poʻe i loaʻa ka liʻiliʻi a ʻaʻohe o nā hōʻailona psoriasis.

A i loko o kahi noiʻi olakino o ka genital psoriasis, 73% o ka poʻe i loaʻa iā Taltz he mau ʻōuli liʻiliʻi wale nō a hoʻomaʻemaʻe paha i kā lākou mau hōʻailona ma hope o 12 mau pule.

Ka hopena no ka plake psoriasis i nā keiki

Ua nānā kahi noiʻi noiʻi pehea i loli ai ʻo Taltz i nā ʻōuli o ka plake psoriasis i nā keiki mai 6 a 18 mau makahiki. Ma hope o 12 mau pule, ua hoʻomaha ʻo Taltz i nā ʻōuli e:

  • ma ka liʻiliʻi 75% ma 89% o nā keiki
  • ma ka liʻiliʻi 90% ma 78% o nā keiki
  • 100% i 50% o nā keiki

ʻO Taltz no spondyloarthritis

Ua ʻae ʻia ʻo Taltz e mālama i ʻelua mau ʻano o spondyloarthritis (SA) i nā mākua. Kūpono ʻia, ʻae ʻia ʻo Taltz e mālama i nā ʻano ʻelua o SA, i hōʻike ʻia ma nā kikoʻī ma lalo:

  • non-radiographic axial spondyloarthritis (nr-axSpA)
  • ʻohana ankylosing spondylitis (AS) a i ʻole radiographic axial spondyloarthritis (r-axSpA)

ʻO SA kahi maʻi maʻi a me kahi ʻano o ke kahe e hōʻeha i kou iwi kuamoʻo. ʻO ka manawa pinepine, pili pū kekahi nā hono kokoke, ʻo ia hoʻi nā hono ʻelua e hoʻohui i kou iwi ʻaoʻao i lalo i kou pelvis (Sacopelvic ami). Ke hōʻike ʻole ka hōʻino i nā hono ma nā kukuna X (radiographs), kapa ʻia ke ʻano o SA ʻo nr-axSpA.

Ke holo a SA, hiki i ka mumū mau (lōʻihi) ke kumu i ka vertebrae i kou iwi kuʻekuʻe e hui pū. A ʻo kahi hopena, e emi ana ka maʻalahi o kou iwi kuamoʻo. ʻO kaʻeha hope a me ka luhi nā hōʻailona maʻamau o SA e holomua nei. Me kēia ʻano SA, hiki ke ʻike ʻia ka pōʻino hui pū ma nā kukuna X. Kapa ʻia kēia ʻano SA i mea hoʻohana AS, a i ʻole r-axSpA.

Ka hopena no ka radiond axial spondyloarthritis

Ua nānā ʻia kahi noiʻi hoʻokolohua i nā mākua nona nā makahiki 18 a ʻoi me ka nr-axSpA. Nānā kēia noiʻi i ka mālama ʻana me Taltz i hoʻohālikelike ʻia me kahi o kahi placebo (lapaʻau me ka lāʻau hana ʻole).

Ma hope o 52 mau pule o ka mālama ʻana:

  • 30% o ka poʻe e hoʻohana ana iā Taltz i hōʻemi ʻia ko lākou mau hōʻailona e 40% a ʻoi paha. Hoʻopili kēia mau ʻōuli i ka ʻoʻoleʻa i kā lākou hono a me ka iwi kuamoʻo.
  • I ka hoʻohālikelike ʻana, 13% o ka poʻe e hoʻohana ana i ka placebo i loaʻa ka hopena like.

Ka hopena no ka ankondose spondylitis ʻeleu

Nānā ʻelua mau noiʻi hoʻokolohua i nā mākua i nā makahiki 18 a ʻoi paha me ka AS ʻeleu. Nānā ʻia kēia mau noiʻi ʻana me Taltz me ka placebo.

Ma hope o 16 mau pule o ka mālama ʻana:

  • 25% a 48% o ka poʻe e hoʻohana ana iā Taltz ua hōʻemi ʻia kā lākou mau hōʻailona e 40% a ʻoi paha. Hoʻopili kēia mau ʻōuli i ka ʻoʻoleʻa i kā lākou hono a me ka iwi kuamoʻo.
  • I ka hoʻohālikelike, 13% a 18% o ka poʻe e hoʻohana ana i ka placebo i loaʻa ka hopena like.

Hoʻohui ʻia, ʻo ka poʻe i lawe iā Taltz, ua ʻemi iki ka ʻeha a ʻike maikaʻi ke kino ke hoʻohālikelike ʻia me ka poʻe i lawe i ka placebo.

ʻO Taltz a me nā keiki

Ua ʻae ʻia ʻo Taltz e mālama i ka plake psoriasis i nā keiki ʻo 6 mau makahiki a ʻoi paha. No nā kikoʻī e pili ana i kēia hoʻohana, e ʻike i ka ʻāpana i luna i kapa ʻia ʻo "Taltz no ka maʻi kaulike a koʻikoʻi hoʻi o ka lāʻau.

ʻO Taltz no nā kūlana ʻē aʻe

Ma waho aʻe o nā hoʻohana i helu ʻia ma luna, hiki ke hoʻohana ʻia ʻo Taltz i kahi lepili no nā kumu ʻē aʻe. ʻO ka hoʻohana ʻana i ka lāʻau lapaʻau i waho ke hoʻohana ʻia kahi lāʻau i ʻae ʻia no hoʻokahi hoʻohana no kahi ʻokoʻa ʻae ʻole ʻia. A noʻonoʻo paha ʻoe inā hoʻohana ʻia ʻo Taltz no kekahi mau ʻano ʻē aʻe.

ʻO Taltz no ka rheumatoid arthritis (hoʻohana inoa ʻole ʻia)

ʻAʻole ʻae ʻia ʻo Taltz e mālama i ka rheumatoid arthritis (RA). Eia nō naʻe, hiki i kāu kauka ke kuhikuhi i ka lāʻau hōʻailona inā ʻaʻole i hana nā lāʻau ʻē aʻe i ʻāpono ʻia nāu.

He maʻi ʻo RA kahi e hoʻouka ai kāu ʻōnaehana pale i kou mau hui, e pehu ana, ʻoʻoleʻa, a ʻeha hoʻi. Ua nānā kekahi mau noiʻi inā hiki iā Taltz ke kōkua i ka mālama ʻana iā RA. Hana ʻo Taltz ma kahi ʻāpana o ka ʻōnaehana pale i ʻike ʻia e hana i kekahi o kēia ami ami (pehu).

Ua hoʻoholo kahi loiloi o nā noiʻi ua maikaʻi ʻo Taltz no ka mālama ʻana iā RA.

Inā makemake ʻoe e ʻike hou e pili ana i ka hoʻohana ʻana iā Taltz e mālama iā RA, e kamaʻilio me kāu kauka.

ʻO Taltz no ka osteoarthritis (ʻaʻole hoʻohana kūpono)

ʻAʻole ʻae ʻia a hoʻohana ʻia paha ʻo Taltz i kahi lepili lāʻau no ka mālama ʻana i ka osteoarthritis. Hoʻokumu ʻia kēia ʻano arthritis e ka lole a weluwelu ma kou mau ami. ʻAʻole ia ma muli o ka pehu. No laila ʻaʻole e kōkua ʻia ka osteoarthritis e nā lāʻau, e like me Taltz, e hoʻopili i kāu ʻōnaehana pale.

Inā he mau nīnau kāu e pili ana i nā koho lapaʻau no ka osteoarthritis, e kamaʻilio me kāu kauka.

ʻO Taltz a me ka waiʻona

ʻAʻole pili pono ka waiʻona i ka hana a Taltz, no laila ʻaʻohe ʻōlelo aʻoaʻo e pili ana i ka hōʻalo ʻana i ka waiʻona i ka wā o Taltz.

Eia nō naʻe, e hōʻeha paha ka inu ʻana i ka waiʻona i ka psoriasis, kahi a Taltz e hoʻohana ai e mālama.Hoʻohui, hiki i ka waiʻona ke hana i ka hoʻomaʻamaʻa ʻana i ka maʻi ʻoi aku ka maikaʻi o ka lāʻau a hiki paha ke hōʻemi i kāu ʻōnaehana pale pale i nā maʻi.

ʻO nā kulekele o kēia manawa no ka mālama ʻana a me ka mālama ʻana i ka psoriasis e ʻōlelo ana e kaupalena i ka nui o ka wai ʻona āu e inu ai.

Inā inu ʻoe i ka waiʻona, e nīnau i kāu kauka i ka nui o ka palekana iā ʻoe e inu ai i ka lawe ʻana iā Taltz.

Nā koho ʻē aʻe iā Taltz

Loaʻa nā lāʻau ʻē aʻe i hiki ke mālama i kou ʻano. Kūpono paha kekahi iā ʻoe ma mua o nā poʻe ʻē aʻe. Inā makemake ʻoe i ka ʻimi ʻana i kahi ʻē aʻe iā Taltz, e kamaʻilio me kāu kauka. Hiki iā lākou ke haʻi iā ʻoe e pili ana i nā lāʻau ʻē aʻe i hana maikaʻi iā ʻoe.

Kaha: Hoʻohana ʻia kekahi o nā lāʻau i helu ʻia ma aneʻi i ka lepili e mālama ai i kēia mau ʻano kikoʻī.

Nā koho ʻē aʻe no ka maʻi psoriatic

ʻO nā laʻana o nā lāʻau ʻē aʻe i hiki ke hoʻohana ʻia e mālama i ka psoriatic arthritis me:

  • methotrexate (Otrexup, Rasuvo, Trexall)
  • apremilast (ʻOtezla)
  • infliximab (Remicade)
  • adalimumab (Humira)
  • etanercept (Enbrel)
  • tofacitinib (Xeljanz)
  • golimumab (Simponi)
  • certolizumab (Cimzia)
  • secukinumab (Cosentyx)
  • ustekinumab (Stelara)
  • brodalumab (Siliq)
  • guselkumab (Tremfya)
  • sulfasalazine (Azulfidine)

Kaha: E aʻo hou aʻe e pili ana i ka psoriatic arthritis, e ʻike i ka ʻāpana ʻo "Taltz hoʻohana" ma luna.

ʻO nā koho ʻē aʻe no ka mea kaulike a paʻakikī hoʻi i ka plake psoriasis

Nā laʻana o nā lāʻau ʻē aʻe i hiki ke hoʻohana ʻia e mālama i ke akau a i ka plake psoriasis koʻikoʻi:

  • apremilast (ʻOtezla)
  • infliximab (Remicade)
  • adalimumab (Humira)
  • etanercept (Enbrel)
  • certolizumab (Cimzia)
  • ustekinumab (Stelara)
  • secukinumab (Cosentyx)
  • brodalumab (Siliq)
  • guselkumab (Tremfya)
  • golimumab (Simponi)
  • methotrexate (Otrexup, Rasuvo, Trexall)
  • sulfasalazine (Azulfidine)

Kaha: E aʻo hou aʻe e pili ana i ka plake psoriasis, e ʻike i ka mahele ʻo "Taltz hoʻohana" ma luna.

Nā koho ʻē aʻe no ka ankylosing spondylitis

Nā laʻana o nā lāʻau ʻē aʻe i hiki ke hoʻohana ʻia e mālama ai i ka spondylitis ankylosing (AS) me:

  • infliximab (Remicade)
  • adalimumab (Humira)
  • etanercept (Enbrel)
  • secukinumab (Cosentyx)
  • certolizumab (Cimzia)
  • golimumab (Simponi)
  • ustekinumab (Stelara)
  • brodalumab (Siliq)
  • methotrexate (Otrexup, Rasuvo, Trexall)
  • sulfasalazine (Azulfidine)

Kaha: E aʻo hou aʻe e pili ana iā AS, e ʻike i ka ʻāpana ʻo "Taltz hoʻohana" ma luna.

Nā koho ʻē aʻe no spondyloarthritis axial axial ʻole radiographic

Nā laʻana o nā lāʻau ʻē aʻe i hiki ke hoʻohana ʻia e mālama ai i ka spondyloarthritis axial non-radiographic (nr-axSpA)

  • certolizumab (Cimzia)
  • adalimumab (Humira)
  • secukinumab (Cosentyx)
  • methotrexate (Otrexup, Rasuvo, Trexall)
  • sulfasalazine (Azulfidine)

Kaha: E aʻo hou aʻe e pili ana i nr-axSpA, e ʻike i ka ʻāpana "Taltz hoʻohana" ma luna.

ʻO Taltz vs. Cosentyx

Mahalo paha ʻoe pehea e hoʻohālikelike ai ʻo Taltz i nā lāʻau ʻē aʻe i kuhikuhi ʻia no nā hoʻohana like. Maanei mākou e nānā ai i ka like a like ʻole o Taltz a me Cosentyx.

E pili ana i

ʻO Taltz lāua ʻo Cosentyx nā lāʻau biologic (nā lāʻau i hana ʻia mai nā ʻāpana o nā meaola ola). Hana lākou ma ka ʻimi ʻana i kahi ʻāpana o kāu ʻōnaehana pale.

Aia ʻo Taltz i ka lāʻau i kona inoa ʻo viekizumab, ʻoiai ʻo Cosentyx i kahi lāʻau secukinumab. Kapa ʻia kēia mau lāʻau ʻelua i nā antibodies monoclonal. Pā lākou i ka hana o kahi protein i loko o kāu ʻōnaehana pale i kapa ʻia interleukin-17. Hoʻokumu ʻo Interleukin-17 i kāu ʻōnaehana pale pale i nā hunaola i kou ʻili a me nā hono. ʻO kēia ke kumu o ka hoʻāhu i ʻike ʻia me nā maʻi e like me ka plaque psoriasis, psoriatic arthritis, a me spondyloarthritis.

Hoʻohana

Ua ʻae ka Food and Drug Administration (FDA) iā Taltz a me Cosentyx e mālama i ka maʻi kaulike a koʻikoʻi i ka lāʻau. Kūpono kēia mau lāʻau no ka poʻe i hiki i ka psoriasis ke keu pono mai ka ʻōnaehana ʻōnaehana (therapy e hoʻohuli i kou kino holoʻokoʻa) a i ʻole phototherapy (mālama māmā).

No ka plaque psoriasis, ʻae ʻia ʻo Taltz no ka hoʻohana ʻana i nā mākua a me nā keiki o nā makahiki 6 a ʻoi. Eia nō naʻe, ʻae wale ʻia ʻo Cosentyx no ka hoʻohana ʻana i nā mākua me kēia ʻano.

Ua ʻae ʻia ʻo Taltz lāua ʻo Cosentyx i ka lāʻau lapaʻau e like me ka psoriatic i nā mākua. ("ʻEleu" ʻo ia hoʻi he mau hōʻailona kāu i kēia manawa.)

Hoʻohui ʻia, ʻae ʻia ʻo Taltz a me Cosentyx no ka mālama ʻana i ka spondyloarthritis axial non-radiographic a me ka spondylitis ankylosing ʻeleu i nā mākua.

Kaha: No ka ʻike hou aku e pili ana i nā kūlana i ʻōlelo ʻia ma aneʻi, e ʻike i ka ʻāpana "Taltz hoʻohana" ma luna.

Nā ʻano lāʻau a me ka hoʻoponopono ʻana

Hāʻawi ʻia ʻo Taltz a me Cosentyx e ka pahu kui ma lalo o kou ʻili (ʻāpana subcutaneous). E hāʻawi aku kāu kauka olakino iā ʻoe i ka injection i ka mua. A laila hiki iā lākou ke aʻo iā ʻoe pehea e hāʻawi ai iā ʻoe iho i ka injection i ka home.

Hele mai ʻo Taltz i nā ʻano ʻelua: kahi syringe prefilled hoʻohana hoʻokahi a me kahi peni autoinjector prefilled hoʻohana hoʻokahi.

Hele mai ʻo Cosentyx i ʻekolu mau ʻano:

  • kahi peni Sensoready hoʻohana hoʻokahi
  • he syringe prefilled hoʻohana hoʻokahi
  • he kiaha hoʻohana hoʻokahi i hāʻawi ʻia ma ke ʻano he injection i hāʻawi ʻia e kāu kauka

Nā hopena a me nā pilikia

Hiki iā Taltz lāua ʻo Cosentyx ke hana i nā hopena ʻaoʻao like a me kekahi ʻokoʻa. Ma lalo nā hiʻohiʻona o kēia mau hopena ʻaoʻao.

Nā hopena ʻaoʻao hou aʻe

Aia i loko o kēia mau papa inoa nā laʻana o nā hopena ʻaoʻao maʻamau e hiki ke hana ʻia me Taltz, me Cosentyx, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).

  • Hiki iā Taltz:
    • nā hopena o ka pūnaewele injection (ʻulaʻula a me ka ʻeha a puni ka ʻāpana ʻāluna
    • conjunctivitis (maka poni)
  • Hiki ke hana me Cosentyx:
    • pāhoehoe
    • ʻeha nā waha
    • ʻāwīwī o ka ʻili
  • Hiki ke hana ʻia me Taltz a me Cosentyx:
    • nā maʻi fungal, e like me ka wāwae o ka ʻālapa
    • nā maʻi hanu o luna, e like me ke anuanu maʻamau
    • nausea

Nā hopena hopena koʻikoʻi

Aia i loko o kēia papa inoa nā laʻana o nā hopena ʻino e hiki ke hana ʻia me Taltz a me Cosentyx (ke lawe pākahi ʻia).

  • hoʻonui i ka makaʻu o nā maʻi i hiki ke koʻikoʻi, e like me ka maʻi kō (TB)
  • hou a i ʻole worsening inflammatory bowel disease (IBD), e like me ka maʻi o Crohn a i ʻole ka ulcerative colitis
  • nā hopena maʻi ʻino nui

Ka hoʻokō ʻana

He ʻano ʻokoʻa kā Taltz lāua ʻo Cosentyx i hoʻohana ʻia e ka FDA, akā hoʻohana ʻia lāua ʻelua e mālama i nā ʻano aʻe:

  • kaulike a hōʻeha loa i ka plake psoriasis
  • psoriatic arthritis e hana nei (ke hana nei i kēia manawa nā ʻōuli)
  • non-radiographic axial spondyloarthritis
  • ʻāʻī ankylosing spondylitis

ʻAʻole i hoʻohālikelike pololei ʻia kēia mau lāʻau i nā noiʻi maʻi. Eia nō naʻe, hoʻokahi loiloi o nā noiʻi o ka plaque psoriasis i ʻike ʻoi aku ka maikaʻi o Taltz ma mua o Cosentyx i ka hōʻemi ʻana i nā ʻōuli o psoriasis.

Paipai nā alakaʻi lapaʻau mai 2018 a me 2019 i nā lāʻau ʻelua i mau koho no nā poʻe e pono i kahi lāʻau olaola no ka psoriasis a me ka psoriatic arthritis. ʻO Biologics kahi ʻano lāʻau e kuhikuhi i nā ʻāpana o kāu ʻōnaehana pale e pili ana i ka psoriasis a me ka psoriatic arthritis.

Hiki paha i kāu kauka ke koi aku i kahi biologic inā ʻaʻole i hana maikaʻi nā mālama ʻē aʻe. ʻO kahi laʻana, kūpono paha iā ʻoe kahi biologic inā:

  • Loaʻa iā ʻoe ka plake psoriasis a me ka light therapy a i ʻole nā ​​mālama ʻana i kau ʻia i kou ʻili ʻaʻole i holo
  • loaʻa iā ʻoe ka psoriatic arthritis a me nā lāʻau anti-inflammatory (kahi e kōkua ai e hōʻemi i ka pehu) e like me nā mea ʻeha a i ʻole steroid i hana ʻole

ʻOi aku paha ka maikaʻi o Cosentyx ma mua o Taltz no ka plake psoriasis e hoʻopili i nā kui. He koho ʻoi aku ka maikaʻi ʻo Taltz no ka erythrodermic psoriasis, kahi ʻano like ʻole o ka psoriasis.

Nā kumukūʻai

ʻO Taltz lāua ʻo Cosentyx nā lāʻau lapaʻau inoa ʻelua. ʻAʻohe ʻano generic o nā lāʻau āpau i kēia manawa. ʻOi aku ke kumu kūʻai o nā lāʻau lapaʻau inoa inoa ma mua o nā generics.

Wahi a nā kuhi ma WellRx.com, ʻo Taltz lāua ʻo Cosentyx ke kumu kūʻai like like. ʻO ke kumukūʻai maoli āu e uku ai no kēlā me kēia lāʻau e pili ana i kāu hoʻolālā ʻinikua, kou wahi, a me ka lāʻau kūʻai āu e hoʻohana ai.

ʻO Taltz vs. Humira

Ma waho aʻe o Cosentyx (ma luna), ʻo Humira kekahi lāʻau i loaʻa kekahi hoʻohana e like me kā Taltz. Maanei mākou e nānā ai i ka like a like ʻole o Taltz lāua ʻo Humira.

E pili ana i

ʻO Taltz lāua ʻo Humira nā lāʻau biologic (nā lāʻau i hana ʻia mai nā ʻāpana o nā meaola ola). Hana lākou pākahi ma ke koho ʻana i nā ʻokoʻa, akā kikoʻī, i nā ʻāpana o kāu ʻōnaehana pale.

Aia i loko o Taltz ka ixekizumab, kahi ʻano lāʻau i kapa ʻia he monoclonal antibody. Pale ia i ka hana o kahi protein i loko o ka ʻōnaehana pale i kapa ʻia interleukin-17. Hoʻokumu ʻo Interleukin-17 i ka ʻōnaehana pale pale i nā hunaola i ka ʻili a me nā hono. ʻO kēia ka hopena i ka hoʻāhu i ʻike ʻia me nā maʻi e like me ka plake psoriasis, psoriatic arthritis, a me spondyloarthritis.

Loaʻa iā Humira adalimumab, kahi ʻano lāʻau i kapa ʻia he tumzeris factor-alpha (TNF-α) blocker. Paʻa ia i ka hana o kahi protein i kapa ʻia ʻo TNF-α. Pili kēia protein i ka hoʻonāukiuki ʻana i nā ʻano like ʻole, e like me ka psoriasis a me ka psoriatic arthritis.

Hoʻohana

Ua ʻae ka Food and Drug Administration (FDA) iā Taltz lāua ʻo Humira e mālama i ka maʻi maʻamau a koʻikoʻi i ka lāʻau. Hiki i kāu kauka ke kauoha i kekahi o kēia mau lāʻau inā hiki i kāu psoriasis ke kōkua mai ka hoʻomaʻamaʻa ʻōnaehana (therapy e hoʻopili i kou kino holoʻokoʻa) a i ʻole phototherapy (mālama māmā).

No ka plaque psoriasis, ʻae ʻia ʻo Taltz no ka hoʻohana ʻana i nā mākua a me nā keiki o nā makahiki 6 a ʻoi. Eia naʻe, ʻae wale ʻia ʻo Humira no ka hoʻohana ʻana i nā mākua me kēia ʻano.

Ua ʻae ʻia ʻo Taltz lāua ʻo Humira e hoʻomaʻamaʻa i ka maʻi psoriatic hana i nā mākua. ("ʻEleu" ʻo ia hoʻi he mau hōʻailona kāu i kēia manawa.)

Hoʻohui ʻia, ʻae ʻia ʻo Taltz lāua ʻo Humira no ka mālama ʻana i ka spondylitis ankylosing ʻeleu i nā mākua. Akā ʻo Taltz wale nō i ʻae ʻia no ka mālama ʻana i ka spondyloarthritis axial non-radiographic i ka poʻe mākua.

Ua ʻae ʻo Humira iā FDA no ka mālama ʻana i kēia mau ʻano:

  • rheumatoid arthritis (RA)
  • kawaena i ka ʻeha ʻōpio ʻōpiopio
  • Maʻi ʻo Crohn
  • kūpono i ke koʻikoʻi ulcerative colitis
  • hidradenitis suppurativa, kahi maʻi ʻehaʻeha hoʻi i kapa ʻia ʻo ka huehue inversa
  • kekahi mau ʻano uveitis noninfectious (kahi ʻano pehu o ka maka), e like me uveitis waena, uveitis hope, a me panuveitis

Kaha: E aʻo hou aʻe e pili ana i ke kūlana ua ʻae ʻia ʻo Taltz e mālama, e ʻike i ka ʻāpana "Taltz hoʻohana" ma luna.

Nā ʻano lāʻau a me ka hoʻoponopono ʻana

Hāʻawi ʻia ʻo Taltz lāua ʻo Humira e ka pahu kui ma lalo o kou ʻili (subcutaneith injection). E hāʻawi aku kāu kauka olakino iā ʻoe i ka injection i ka mua. A laila hiki iā lākou ke aʻo iā ʻoe pehea e hāʻawi ai iā ʻoe iho i ka injection i ka home.

Hele mai ʻo Taltz i nā ʻano ʻelua: kahi syringe prefilled hoʻohana hoʻokahi a me kahi peni autoinjector prefilled hoʻohana hoʻokahi.

Hele mai ʻo Humira i ʻekolu mau ʻano:

  • he peni piha i hoʻohana mua ʻia
  • he syringe prefilled hoʻohana hoʻokahi
  • he kiaha hoʻohana hoʻokahi i hāʻawi ʻia ma ke ʻano he injection i hāʻawi ʻia e kāu kauka

Nā hopena a me nā pilikia

Hiki iā Taltz lāua ʻo Humira ke hana i nā hopena ʻaoʻao like a me kekahi mau ʻano ʻokoʻa. Ma lalo nā hiʻohiʻona o kēia mau hopena ʻaoʻao.

Nā hopena ʻaoʻao hou aʻe

Aia i loko o kēia mau papa inoa nā laʻana o nā hopena ʻaoʻao maʻamau e hiki ke hana ʻia me Taltz, me Humira, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).

  • Hiki iā Taltz:
    • nā maʻi fungal tinea, e like me ka wāwae o ka ʻālapa
    • conjunctivitis (maka poni)
  • Hiki iā Humira:
    • ʻeha poʻo
    • hūwī
  • Hiki ke hana me Taltz lāua ʻo Humira:
    • nā hopena pae o ke ʻūlū, e like me ka ʻulaʻula a me ka ʻeha a puni ka ʻāpana ʻāpana
    • nā maʻi hanu o luna, e like me ke anuanu maʻamau
    • nausea

Nā hopena hopena koʻikoʻi

Loaʻa i kēia mau papa inoa nā laʻana o nā hopena ʻino e hiki ke kū ʻia me Taltz, me Humira, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).

  • Hiki iā Taltz:
    • hou a i ʻole worsening inflammatory bowel disease (IBD), e like me ka maʻi o Crohn a i ʻole ka ulcerative colitis
  • Hiki iā Humira:
    • nā pilikia o ke ake, e like me ke kō ʻole o ke ake
    • nā pilikia ʻōnaehana, e like me nā sclerosis (MS).
    • nā pilikia o ke koko, e like me ka hōʻemi ʻana o nā hunaola ʻulaʻula, nā ʻula koko keʻokeʻo, a i ʻole nā ​​platelet
    • puʻuwai puʻuwai
    • nā maʻi fungal, e like me histoplasmosis
    • hoʻonui i ka makaʻu o kekahi mau maʻi ʻaʻai, e like me ka maʻi ʻaʻai ʻili, leukemia, a me ka lymphoma
    • psoriasis hou a ʻinoʻino paha
  • Hiki ke hana me Taltz lāua ʻo Humira:
    • hoʻonui i ka makaʻu o nā maʻi i hiki ke koʻikoʻi, e like me ka maʻi kō (TB)
    • nā hopena maʻi ʻino nui

Ka hoʻokō ʻana

He ʻano ʻokoʻa kā Taltz lāua ʻo Humira i hoʻohana ʻia e ka FDA, akā hoʻohana ʻia lāua ʻelua e mālama i nā ʻano aʻe:

  • kaulike a hōʻeha loa i ka plake psoriasis
  • ʻeleʻele psoriatic arthritis
  • ʻO ka spondylitis hana ankylosing

ʻAʻole i hoʻohālikelike pololei ʻia kēia mau lāʻau i loko o ka poʻe me ka psoriasis plaque, akā ua ʻike ʻia kahi noiʻi ua maikaʻi ʻo Taltz a me Humira no ka mālama ʻana i kēia ʻano.

Nānā hoʻokahi kahi noiʻi noiʻi i nā Taltz a me Humira i nā poʻe me ka maʻi psoriatic hana. Ma hope o 24 mau wiki, ua hōʻemi ʻia nā ʻōuli psoriatic e 20% ma 58% a 62% o ka poʻe i lawe iā Taltz. Hoʻohālikelike ʻia kēia me 57% o ka poʻe i lawe iā Humira a me 30% i lawe i kahi placebo (ʻaʻohe lapaʻau).

Paipai nā alakaʻi lapaʻau mai 2018 a me 2019 i nā lāʻau ʻelua i mau koho no nā poʻe e pono i kahi lāʻau biologic no psoriasis a me psoriatic arthritis. ʻO Biologics kahi ʻano lāʻau e kuhikuhi i nā ʻāpana o kāu ʻōnaehana pale e pili ana i ka psoriasis a me ka psoriatic arthritis.

Hiki paha i kāu kauka ke koi aku i kahi biologic inā ʻaʻole i hana maikaʻi nā mālama ʻē aʻe. ʻO kahi laʻana, kūpono paha iā ʻoe kahi biologic inā:

  • Loaʻa iā ʻoe ka plake psoriasis a me ka light therapy a i ʻole nā ​​mālama ʻana i kau ʻia i kou ʻili ʻaʻole i holo
  • loaʻa iā ʻoe ka psoriatic arthritis a me nā anti-inflammatory treatment (kahi e kōkua ai e hōʻemi i ka pehu) e like me nā mea ʻeha a i ʻole steroid i hana ʻole

No ka hapanui o ka poʻe e hoʻomaka nei i ka mālama ʻana no ka psoriatic arthritis ʻeleu, paipai nā kulekele 2018 e hoʻohana ana i nā blockers TNF-alpha (e like me Humira) ma luna o nā interleukin-17 blockers (e like me Taltz). Ua ʻōlelo ʻia nā kulekele 2019 e ʻoi aku ka maikaʻi o Humira ma mua o Taltz no ka pākuʻi psoriasis e pili ana i ka ʻili a no ka erythrodermic psoriasis (kahi ʻano maʻamau o ka psoriasis).

Hoʻohālikelike kahi noiʻi maʻi i ka maikaʻi o Taltz a me Humira i ka mālama ʻana i ka psoriatic arthritis a me ka plaque psoriasis. Ua hōʻike ʻia kahi noiʻi ma kahi o 24 mau pule o ka mālama ʻana, 36% o ka poʻe i lawe iā Taltz i hoʻomaikaʻi ʻia ko lākou mau hōʻailona ma kahi o 50%. I ka hoʻohālikelike ʻana, 28% o ka poʻe i lawe iā Humira i hoʻomaikaʻi i ko lākou mau hōʻailona ma kahi o 50%.

Nā kumukūʻai

ʻO Taltz lāua ʻo Humira nā lāʻau lapaʻau inoa inoa ʻelua. ʻAʻohe ʻano generic o nā lāʻau āpau i kēia manawa. ʻOi aku ke kumu kūʻai o nā lāʻau lapaʻau inoa inoa ma mua o nā generics.

Wahi a nā kuhi ma WellRx.com, ʻo Taltz lāua ʻo Humira ke kumu kūʻai o nā mea like. ʻO ke kumukūʻai maoli āu e uku ai no kēlā me kēia lāʻau e pili ana i kāu hoʻolālā ʻinikua, kou wahi, a me ka lāʻau kūʻai āu e hoʻohana ai.

Nā pilina ʻo Taltz

Hiki iā Taltz ke launa pū me kekahi lāʻau ʻē aʻe. Hiki i nā launa like ʻole ke kumu i nā hopena like ʻole. ʻO kahi laʻana, hiki i kekahi mau pilina ke hoʻopilikia me ka maikaʻi o ka hana ʻana o ka lāʻau. Hiki i nā pilina ʻē aʻe ke hoʻonui i nā hopena a i ʻole e hoʻonui i ke koʻikoʻi.

ʻO Taltz a me nā lāʻau ʻē aʻe

Ma lalo ka papa inoa o nā lāʻau i hiki ke launa pū me Taltz. ʻAʻohe i loko o kēia papa inoa nā lāʻau āpau e launa pū ana me Taltz.

Ma mua o ka lawe ʻana iā Taltz, e kamaʻilio me kāu kauka a me kāu kauka lāʻau. E haʻi iā lākou e pili ana i nā kuhikuhi āpau, nā mea kūʻai aku, a me nā lāʻau ʻē aʻe āu e lawe ai. E haʻi pū iā lākou e pili ana i nā wikamina, nā mea kanu, a me nā mea hoʻopiha āu e hoʻohana ai. Hiki ke kōkua i ka hāʻawi ʻana i kēia ʻike iā ʻoe e hōʻalo i nā launa ʻole.

Inā he mau nīnau kāu e pili ana i nā launa lāʻau e hoʻopili iā ʻoe, e nīnau i kāu kauka a kauka paha.

ʻO Taltz a me warfarin

ʻO Warfarin (Coumadin, Jantoven) kahi ʻano o ka lahilahi o ke koko, kahi lāʻau e kōkua i ka pale ʻana i ke koko. ʻO ka lawe ʻana iā Taltz me warfarin e hoʻoliʻiliʻi paha ka hopena i kāu warfarin.

Inā lawe ʻoe i warfarin, makemake paha kāu kauka e nānā i ka lōʻihi o ke kō ʻana o kou koko ma hope o kou hoʻomaka ʻana iā Taltz, i ka wā o kou lapaʻau ʻana, a inā ʻoe e kāpae iā Taltz. Hiki iā lākou ke hoʻoponopono i kāu mea o warfarin inā pono.

ʻO Taltz a me cyclosporine

ʻO Cyclosporine kahi lāʻau immunosuppressant. Lawe ʻoe iā ia e hōʻemi i ka hana o kāu ʻōnaehana pale. ʻO ka lawe ʻana iā Taltz me ka cyclosporine e hoʻoliʻiliʻi paha ka maikaʻi i kāu cyclosporine.

Inā ʻoe e lawe nei i ka cyclosporine, makemake paha kāu kauka e nānā i ke kiʻekiʻe o ka lāʻau i loko o kou koko ma hope o kou hoʻomaka ʻana iā Taltz, i kou wā e mālama ai a inā kū ʻoe iā Taltz. Hiki iā lākou ke hoʻoponopono i kāu mea o ka cyclosporine inā pono.

Loaʻa ʻo Cyclosporine e like me nā lāʻau inoa inoa inoa aʻe:

  • Cequa
  • ʻO Gengraf
  • Neoral
  • Hoʻomaha Hou
  • ʻO Sandimmune

ʻO Taltz a me nā lāʻau ola

ʻO ka loaʻa ʻana o kahi lāʻau lapaʻau ola ʻoiai ʻoe e lawe nei iā Taltz hiki ke hana i nā maʻi koʻikoʻi.

Loaʻa nā lāʻau lapaʻau ola i nā ʻano nāwaliwali o nā mea ʻino a i ʻole nā ​​koʻohune, akā ʻaʻole lākou e kumu i nā maʻi i nā poʻe me nā ʻōnaehana pale ola olakino. Eia nō naʻe, hiki i nā lāʻau āpau ke kumu i nā maʻi i nā poʻe nona nā ʻōnaehana paleʻea e hoʻopili ʻia e Taltz.

ʻOiai ʻoe e lawe nei iā Taltz, ʻaʻole pono ʻoe e loaʻa nā lāʻau ola e like me:

  • maʻi puʻupuʻu
  • fever fever
  • tuberculosis (TB)
  • measles, mumps, and rubella (MMR)

Maikaʻi ke kiʻi ʻana i nā lāʻau āpau hana ʻole (ʻaʻole ola), e like me ke kī ʻana o ka maʻi flu, i kou wā e mālama ai iā Taltz. Eia nō naʻe, ʻaʻole holo pono nā lāʻau kūmau ʻole e like me ka hana maʻamau. (Hana ka lāʻau lapaʻau ma o ka hoʻoulu ʻana i kāu ʻōnaehana pale pale e hana i nā mea pale e kōkua ai i ke kaua ʻana i nā maʻi. E hoʻoliʻiliʻi paha ʻo Taltz i kāu ʻōnaehana pale i ka hana ʻana i nā mea pale.

Inā makemake kāu kauka iā ʻoe e lawe iā Taltz, e nīnau inā pili ʻoe i nā lāʻau āpau āpau i ʻōlelo ʻia.

ʻO Taltz a me nā mea kanu a me nā mea hoʻopili

ʻAʻohe mea kanu a mea hoʻopili paha i hōʻike kikoʻī ʻia e launa pū me Taltz. Akā e nānā pono me kāu kauka lāʻau ma mua o ka hoʻohana ʻana i kekahi.

Pehea e lawe ai iā Taltz

Hāʻawi ʻia ka lāʻau lapaʻau e ka pahu kui ma lalo o kou ʻili (subcutaneous injection). E hāʻawi aku kāu kauka olakino iā ʻoe i ka injection i ka mua. A laila hiki iā lākou ke aʻo iā ʻoe pehea e hāʻawi ai iā ʻoe iho i ka injection i ka home. Hiki iā ʻoe ke lawe i kāu injection Taltz i kēlā me kēia manawa o ka lā i ka lā e kūpono ai.

Hele mai ʻo Taltz ma ke ʻano he syringe prefilled hoʻokahi a me kahi peni autoinjector prefilled hoʻokahi hoʻohana. E nīnau i kāu kauka i ka mea kūpono iā ʻoe. Loaʻa i nā ʻano ʻelua i hoʻokahi mahele lāʻau. Hoʻopili ʻoe i ka mahele piha a laila hoʻolei i ka syringe a i ʻole ka peni autoinjector.

I ka manawa hea e lawe ai

Ke pono ʻoe e lawe i nā kaha o Taltz ma muli o ke ʻano i mālama ʻia. ʻO ka maʻamau, e loaʻa iā ʻoe kāu mahele lāʻau mua o Taltz ma ke keʻena o kāu kauka. A laila hiki iā ʻoe ke hāʻawi i kēia mau injection iā ʻoe iho.

Ma lalo, wehewehe mākou i nā papa hana hana maʻamau no Taltz no kāna hoʻohana ʻae ʻia.

  • Inā loaʻa iā ʻoe ka psoriasis: No kāu mahele lāʻau mua o Taltz, e loaʻa iā ʻoe i ʻelua injection i ka lā like. Ma hope o ka mahele lāʻau mua o Taltz, loaʻa iā ʻoe hoʻokahi kaomi ʻana i kēlā me kēia 2 mau pule no 12 mau pule. E ukali ʻia kēia e hoʻokahi injection i kēlā me kēia 4 mau pule no ka lōʻihi o ke kauka a ke kauka.
  • Inā loaʻa iā ʻoe ka maʻi psoriatic: No kāu mahele lāʻau mua o Taltz, e loaʻa iā ʻoe i ʻelua injection i ka lā like. Ma hope o ka mahele lāʻau mua o Taltz, e loaʻa ʻoe i hoʻokahi injection i kēlā me kēia 4 mau pule no ka lōʻihi o ke kauka
  • Inā loaʻa iā ʻoe ka psoriasis a me ka psoriatic arthritis: E loaʻa iā ʻoe nā puʻupuʻu Taltz e pili ana i ka papa kuhikuhi dosing i manaʻo ʻia no ka psoriasis, i hōʻike ʻia ma luna.
  • Inā loaʻa iā ʻoe ka spondyloarthritis axial non-radiographic (nr-axSpA): Ma hope o kāu mahele lāʻau mua o Taltz, loaʻa iā ʻoe hoʻokahi kaomi ʻana i kēlā me kēia 4 pule.
  • Inā loaʻa iā ʻoe ka ankylosing spondylitis (AS): No kāu mahele lāʻau mua o Taltz, e loaʻa iā ʻoe i ʻelua injection i ka lā like. Ma hope o ka mahele lāʻau mua o Taltz, e loaʻa ʻoe i hoʻokahi injection i kēlā me kēia 4 pule.

No ka hana maikaʻi ʻana a Taltz, he mea nui ia e lawe e like me ke kauka a kāu kauka. I mea e hoʻomanaʻo ai i ka lawe ʻana i ka lāʻau, he mea maikaʻi ke kākau ʻana i kāu papa kuhikuhi i loko o ka kalena. Hiki nō hoʻi iā ʻoe ke hoʻohana i kahi mea hoʻomanaʻo hoʻomanaʻo i ka lāʻau i poina ʻole iā ʻoe.

Kaha: No ka ʻike hou aku e pili ana i nā kūlana i helu ʻia ma aneʻi, e ʻike i ka ʻāpana "Taltz hoʻohana" ma luna.

Pehea e hoʻopili ai

E aʻo aku kāu mea mālama ola iā ʻoe pehea e hoʻohana ai i ka syringe a i ʻole ka autoinjector pen. No ka ʻike hou aku, i nā wikiō, a me nā kiʻi o ke kuhikuhi i ka hoʻopili ʻana, e ʻike i ka pūnaewele o ka mea hana.

E hoʻomanaʻo i nā pūnaewele kūpono e hoʻokomo iā Taltz i mua o kou ʻūhā a i ʻole kou ʻōpū (ʻōpū). Hiki iā ʻoe ke hoʻohana i ka hope o kou mau lima kiʻekiʻe, akā pono ʻoe i kahi mea ʻē aʻe e hāʻawi iā ʻoe i ka injection.

Pehea e hana ai ʻo Taltz

ʻO nā maʻi he psimatic, psoriatic arthritis, a me spondyloarthritis. Hoʻokumu lākou i kāu ʻōnaehana pale (ke pale ʻana o kou kino i nā maʻi) e hoʻouka hewa i nā hunaola olakino.

No ka 'ike hou aku e pili ana i kēia mau kūlana, e nānā i ka "Taltz hoʻohana" mahele i luna.

Pili nā ʻāpana like ʻole o ka ʻōnaehana pale pale i kēlā me kēia ʻano. Pili kekahi hana kikoʻī i kahi protein i kapa ʻia interleukin-17A. ʻLelo kēia protein i kāu ʻōnaehana pale pale e hoʻouka i nā hunaola i kou ʻili a me nā hono.

Aia i loko o Taltz ka ixekizumab, kahi ʻano lāʻau i kapa ʻia he antibody monoclonal humanized. Hana ia ma ke hoʻopaʻa ʻana (hoʻopili) i interleukin-17A. I ka hana ʻana i kēia, ālai ʻo Taltz i ka hana o ka protein. Kū ka mea iā ia mai ka haʻi ʻana i kāu ʻōnaehana pale pale i nā hunaola i kou ʻili a me nā hono.

I ka pale ʻana i kāu ʻōnaehana pale maʻi mai ka hoʻouka ʻana i nā hunaola, kōkua ʻo Taltz:

  • e ho'ēmi i ka hoʻokumu ʻia ʻana o nā pā i kou ʻili i ka psoriasis plake
  • e ho'ēmi i ka hoʻohaʻahaʻa (pehu) o kou mau hono i ka psoriatic arthritis, non-radiographic axial spondyloarthritis, a me ka ankylosing spondylitis

Pehea ka lōʻihi o ka hana?

Hoʻomaka ʻo Taltz e hana ke hoʻomaka ʻoe i ka lāʻau. Eia nō naʻe, e hala paha kekahi mau pule iā ʻoe e ʻike ai i nā loli.

I nā noiʻi hoʻokolohua, ʻo ka hapanui o ka poʻe me ka psoriasis plaque i maopopo a ʻaneʻane e hoʻomaʻemaʻe i ka ʻili 12 mau pule ma hope o ka hoʻomaka ʻana o ka mālama ʻana a ma mua paha. A ma kahi o ka hapalua o ka poʻe me psoriatic arthritis nāna i lawe iā Taltz i loaʻa nā hōʻailona ʻoi loa a me ka maikaʻi o ke kino e 12 mau pule ma hope o ka hoʻomaka ʻana o ka lapaʻau.

Ua nānā ʻia kahi noiʻi olakino o nā mākua me ka spondyloarthritis axial non-radiographic i ka lapaʻau ʻana me Taltz a me ka mālama ʻana me kahi placebo. (ʻO kahi placebo kahi lāʻau me ka lāʻau ʻole.) Ma hope o 52 mau pule o ka hoʻomaʻamaʻa ʻana, 30% o ka poʻe e hoʻohana ana iā Taltz ua hōʻemi ʻia ko lākou mau hōʻailona e 40% hou aʻe. I ka hoʻohālikelike ʻana, 13% o ka poʻe e hoʻohana ana i ka placebo i loaʻa ka hopena like.

ʻElua mau noiʻi pilikino o nā mākua me ka spondylitis ankylosing e nānā ana i ka mālama ʻana me Taltz i hoʻohālikelike ʻia me kahi o kahi placebo. Ma hope o 16 mau pule o ka mālama ʻana, 25% a 48% o ka poʻe e hoʻohana ana iā Taltz ua hōʻemi ʻia ko lākou mau hōʻailona e 40% a ʻoi paha. I ka hoʻohālikelike, 13% a 18% o ka poʻe e hoʻohana ana i ka placebo i loaʻa ka hopena like.

ʻO Taltz a me ka hāpai ʻana

ʻAʻole i aʻo ʻia ʻo Taltz i nā wahine hāpai, no laila ʻaʻole ʻike ʻia inā palekana ka lāʻau i ka wā hāpai.

E ʻike pono e haʻi aku i kāu kauka inā hāpai ʻoe a ke hoʻolālā nei i kahi hāpai ma mua o kou hoʻomaka ʻana i ka lāʻau. Inā manaʻo ʻoe hiki iā ʻoe ke hāpai i ka lawe ʻana iā Taltz, e kamaʻilio koke me kāu kauka.

ʻO Taltz a me ka kaohi hānau

ʻAʻole ʻike ʻia inā palekana ʻo Taltz i ka wā hāpai. Inā hana kolohe ʻoe a hiki i kāu a i ʻole kāu pakanā ke hāpai, e kamaʻilio me kāu kauka e pili ana i kāu pono hanau hānau ke hoʻohana nei ʻoe iā Taltz.

No ka ʻike hou aku e pili ana i ka lawe ʻana iā Taltz i ka wā hāpai, e ʻike i ka ʻāpana ʻo "Taltz a hāpai" ma luna.

ʻO Taltz a me ka waiū hānai

ʻAʻole ʻike ʻia inā hele ʻo Taltz i loko o ka waiū umauma kanaka a i ʻole inā pili ia i ka hana ʻana o kou kino i ka waiū umauma. Ua loaʻa ʻo Taltz i ka waiū umauma i nā noiʻi holoholona, ​​akā ʻaʻole hōʻike mau ka noiʻi ʻana i nā holoholona i ka mea e hiki i nā kānaka.

Inā hānai ʻoe i ka waiū a noʻonoʻo e lawe iā Taltz, e kamaʻilio me kāu kauka. Hiki iā lākou ke kūkākūkā i nā pilikia a me nā pono o ka lāʻau me ʻoe.

Nā nīnau e pili ana iā Taltz

Eia nā pane i kekahi o nā nīnau e nīnau pinepine ʻia e pili ana iā Taltz.

He biologic ʻo Taltz?

Ae. ʻO Taltz kahi lāʻau olaola. ʻO kēia ke ʻano o ka lāʻau i hana ʻia mai nā protein a ʻaʻole hoʻi mai nā kemika (e like me ka nui o nā lāʻau). Hana ʻia nā lāʻau biologic i kahi lab e hoʻohana ana i nā hunaola holoholona.

E pono anei wau e hoʻohana i nā kalima kumuhana no psoriasis ke hoʻohana nei ʻo Taltz?

Maliʻa paha. Akā pono ʻoe e hāhai i nā ʻōlelo aʻoaʻo a kāu kauka e pili ana i kēia.

Inā holoi loa kou ʻili ma hope o ka lawe ʻana iā Taltz, a laila ʻaʻole pono ʻoe e hoʻomau i ka hoʻohana ʻana i nā mālama kumuhana. Akā i kekahi mau hihia, loaʻa paha iā ʻoe kekahi mau plake psoriasis (mānoanoa, ʻulaʻula, pākuʻi scaly ma kou ʻili). Inā kū kēia, hiki i kāu kauka ke koi iā ʻoe e hoʻohana i nā moisturizers a i ʻole nā ​​mālama kumuhana ʻē aʻe e pono ai. E hāhai mau i nā ʻōlelo aʻo a kāu kauka i hāʻawi ai iā ʻoe.

Hiki i ka hoʻohana ʻana iā Taltz ke kumu i ka maʻi ʻōpū a ʻōpala hou paha?

ʻAe hiki, ʻoiai he kākaʻikahi kēia. ʻO ka maʻi maʻi ʻōpū (IBD) kahi hui o nā maʻi e hoʻonā i ka wela (pehu) i kāu wahi digestive. Hoʻopili kēia mau maʻi i ka maʻi o Crohn a me ka ulcerative colitis.

I nā noiʻi hoʻokolohua, ua loaʻa ka maʻi o Crohn i ka 0,1% o ka poʻe me ka pālau psoriasis i loaʻa iā Taltz. Ua loaʻa ka ulcerative colitis ma 0,2% o ka poʻe me ka plaque psoriasis i loaʻa iā Taltz.

Inā loaʻa iā ʻoe nā hōʻailona hou a ʻino paha o ka IBD, e ʻike i kāu kauka. Pākuʻi ʻia paha nā ʻōuli me ka ʻeha o kou ʻōpū (ʻōpū), ka maʻi hē me a i ʻole me ke koko ʻole, a me ka pohō kaumaha.

He aha kaʻu e hana ai e pale aku ai i nā maʻi i ka wā e lawe ai wau iā Taltz?

Hiki iā Taltz ke hoʻonāwaliwali i kahi o kāu ʻōnaehana pale, no laila hiki i ka lāʻau ke hoʻonui i kou makaʻu i ka loaʻa ʻana o nā maʻi. Eia kekahi ʻōlelo aʻoaʻo e kōkua ai i ka mālama ʻana i kāu ʻōnaehana pale maʻi a kōkua iā ʻoe e hōʻalo i nā maʻi.

  • Ma mua o kou hoʻomaka ʻana i ka lāʻau, e kamaʻilio me kāu kauka e pili ana i kēia lā me nā lāʻau āpau i koi ʻia.
  • E holoi pinepine i kou mau lima, keu hoʻi inā ʻoe ma kahi lehulehu.
  • E hoʻāʻo e hōʻole i ka pili pili loa ʻana i ka poʻe i loaʻa i ka maʻi, keu hoʻi i ka ʻū, ke anu, a me ka maʻi flu.
  • Hōʻalo i ka kaʻana like ʻana i nā kāwele a i nā ʻeke holoi me nā mea i loaʻa i ka ʻili fungus a i ʻole ʻeha anu.
  • ʻAi i kahi papaʻai olakino.
  • E lawa ka hiamoe.
  • Mai puhi.

Hoʻola ʻo Taltz i ka pāleka psac a i ʻole psoriatic arthritis?

ʻAʻole, ʻaʻole hoʻōla ʻo Taltz i kēia mau ʻano. ʻAʻohe mea ola i kēia manawa no ka plake psoriasis a i ʻole psoriatic arthritis. Akā kōkua ka mālama wā lōʻihi me Taltz i ka pale ʻana i nā ʻōuli o kēia mau kūlana.

Ninaninau ʻia nā noiʻi hoʻokolohua i ka poʻe me ka plake psoriasis nāna i lawe iā Taltz. Ua hoʻomaʻemaʻe holoʻokoʻa kahi mau ʻōuli o kekahi poʻe a ua liʻiliʻi paha ma hope o 12 mau pule. A laila lawe ka hapalua o kēia hui iā Taltz no 48 mau pule ʻē aʻe. Ua lawe ka hapalua o ka hui i kahi placebo (ʻaʻohe lapaʻau) no 48 mau pule.

ʻO ka poʻe i mālama mau iā Taltz, 75% ʻaʻole i loaʻa a i ʻole nā ​​hōʻailona liʻiliʻi ma ka hopena o ke aʻo ʻana. No ka hapanui o ka poʻe i lawe i kahi placebo, ua hele a hewa hou kā lākou mau ʻōuli. ʻO 7% wale nō o ka hui placebo i loaʻa ʻole a i ʻole nā ​​ʻōuli liʻiliʻi. ʻO ka manawa maʻamau i lawe ʻia no nā ʻōuli e ʻoi aku ka maikaʻi i ka poʻe i lawe i kahi placebo he 164 mau lā. Akā ke hoʻomaka hou lākou i ka lawe ʻana iā Taltz, no 66% o kēia poʻe, ua holoi ʻia kā lākou psoriasis i loko o 12 mau pule.

Nā hana aka Taltz

Ma mua o ka lawe ʻana iā Taltz, e kamaʻilio me kāu kauka e pili ana i kāu mōʻaukala olakino. ʻAʻole kūpono paha ʻo Taltz iā ʻoe inā loaʻa iā ʻoe kekahi ʻano olakino. Pākuʻi ʻia kēia mau mea:

  • ʻO kekahi maʻi, akā tuberculosis nō. Hiki iā Taltz ke hoʻolilo i kou ʻōnaehana pale i ka hiki ʻole ke kaua i nā g germ, no laila hiki i nā maʻi e like me ka tuberculosis (TB) ke lilo i koʻikoʻi.
    • Inā loaʻa ʻoe iā TB i kēia manawa a i ʻole he TB kāu i ka wā ma mua, pono paha ʻoe e lawe i ka lāʻau e mālama ai. Ke mālama ʻia ka TB, hiki paha iā ʻoe ke hoʻomaka e lawe iā Taltz.
    • Inā loaʻa iā ʻoe nā ʻōuli o nā maʻi ʻē aʻe, e like me ke kuni, a inā loaʻa ʻoe i nā maʻi e hoʻi hou ana, e haʻi i kāu kauka. Pono e mālama ʻia kēia mau maʻi ma mua o ka hiki iā ʻoe ke hoʻomaka i ka mālama ʻana me Taltz.
  • Maʻi maʻi ʻōpū. I nā hihia kakaikahi, hiki iā Taltz ke hōʻeha i nā ʻōuli o ka maʻi ʻōpū (IBD). ʻO IBD kahi hui o nā maʻi e komo pū me ka maʻi o Crohn a me ka ulcerative colitis. Inā he IBD kāu, e kamaʻilio me kāu kauka. Hiki iā lākou ke nānā i kāu mau ʻōuli ke lawe ʻoe iā Taltz. Inā piʻi hewa kou IBD, pono paha ʻoe e kāohi iā Taltz. Aia kekahi mau lāʻau biologic ʻē aʻe e hōʻino ʻole iā IBD i hiki iā ʻoe ke hoʻāʻo.

Kaha: No ka ʻike hou aku e pili ana i nā hopena maikaʻi ʻole o Taltz, e ʻike i ka ʻāpana "Taltz hopena" ma luna.

ʻO Taltz overdose

Loaʻa i kēlā me kēia syringe prefilled a me ka peni autoinjector i ka nui kūpono o ka lāʻau no hoʻokahi mahele. No laila hiki wale kahi overdose inā hāʻawi ʻoe iā ʻoe iho i nā injection he nui a i ʻole inā lawe pinepine ʻoe iā Taltz.

Nā hōʻailona overdose

Hiki i nā ʻōuli o ka overdose ke hoʻopili i nā hopena ʻē aʻe i lilo i pinepine a ʻoi aku paha ke koʻikoʻi, e like me:

  • nā maʻi hanu o luna, e like me ke anuanu maʻamau
  • nausea
  • nā maʻi fungal, e like me ka wāwae o ka ʻālapa
  • nā hopena maʻi ʻino nui
  • ʻo ka maʻi ʻōpū (IBD), e like me ka maʻi o Crohn a i ʻole colitis ulcerative
  • hoʻonui i ka makaʻu o nā maʻi, e like me ka maʻi kō (TB)

He aha e hana ai inā he overdose

Inā manaʻo ʻoe ua lawe nui ʻoe i kēia lāʻau, e kāhea i kāu kauka. Hiki iā ʻoe ke kāhea i ka ʻAmelika Hui Pū ʻIa o nā Poison Control ma 800-222-1222 a i ʻole hoʻohana i kā lākou mea hana pūnaewele. Akā inā koʻikoʻi kāu mau ʻōuli, e kāhea iā 911 a i ʻole e hele koke i kahi lumi pilikia kokoke.

Pau ʻo Taltz, mālama, a hoʻolei

Ke kiʻi ʻoe iā Taltz mai ka hale kūʻai lāʻau, e hoʻohui ka kauka i kahi lā palena pau i ka lepili ma ka ʻōmole. ʻO kēia lā he 1 mau makahiki ia mai ka lā a lākou i hāʻawi ai i ka lāʻau.

Kōkua ka lā palena i ka hōʻoia ʻana i ka maikaʻi o nā lāʻau i kēia manawa. ʻO ke kūlana o ka Food and Drug Administration (FDA) i kēia manawa e hōʻalo i ka hoʻohana ʻana i nā lāʻau i make. Inā loaʻa iā ʻoe kahi lāʻau i hoʻohana ʻole ʻia i hala i ka lā palena pau, e nīnau i kāu kauka lāʻau inā paha hiki iā ʻoe ke hoʻohana.

Waihona

Pehea ka lōʻihi o ka maikaʻi o ka lāʻau e hiki ai ke hilinaʻi i nā kumu he nui, e like me pehea a ma hea ʻoe e mālama ai i ka lāʻau.

Pono e mālama ʻia ʻo Taltz prefilled syringes a me nā peni autoinjector i loko o ka pahu hau ma 36 ° F a 46 ° F (2 ° C a 8 ° C). E hōʻoia i ka hiki ʻole i nā keiki. Mai hoʻopaʻa iā Taltz. A mai hoʻohana i ka lāʻau inā ua paʻahau.

I kekahi mau hihia, pono ʻoe e lawe iā Taltz mai ka pahu hau ma mua o ka hoʻohana ʻana iā ia. ʻO kahi laʻana, inā e hele ana ʻoe no kekahi mau lā a pono kahi injection i kēlā manawa. ʻIke hiki iā ʻoe ke mālama iā Taltz i ka mahana o ka lumi a i ka 86 ° F (30 ° C) a i 5 mau lā.

E mālama pono i ka syringe a i ʻole ka peni autoinjector i loko o kāna pahu pahu kumu e pale aku ai iā ia mai ka mālamalama. Inā ʻaʻole ʻoe e hoʻohana i kahi syringe a i ʻole ka peni i loko o 5 mau lā, pono ʻoe e hoʻolei palekana iā ia. ʻAʻole pono ʻoe e hoʻihoʻi iā Taltz i loko o ka pahu hau i ka manawa e mālama ʻia ai i ka mahana wela.

Hoʻolei

Ma hope o kāu hoʻohana ʻana i kahi syringe prefilled a Taltz a i ʻole ka peni autoinjector, e hoʻokomo i loko o kahi pahu hoʻolei sharps i ʻae ʻia e FDA. Kōkua kēia i ka pale aku i nā poʻe ʻē aʻe, e like me nā keiki a me nā holoholona, ​​mai ka lawe lāʻau ʻana ʻole. Mālama pū kekahi ia i ka lāʻau mai hōʻino i ke kaiapuni.

Inā ʻaʻohe ou pahu sharps, hiki iā ʻoe ke kūʻai i hoʻokahi ma ka pūnaewele ma kāu kauka lāʻau kūloko.

Hiki iā ʻoe ke loaʻa nā ʻōlelo aʻoaʻo maikaʻi e pili ana i ka hoʻolei ʻana i ka lāʻau ma aneʻi. Hiki iā ʻoe ke nīnau i kāu kauka lāʻau no nā ʻōlelo aʻoaʻo e pili ana i ka hoʻolilo ʻana i kāu lāʻau.

ʻO ka ʻike ʻoihana no Taltz

Hāʻawi ʻia ka ʻike aʻe no nā kauka lapaʻau a me nā ʻoihana ola.

Nā Hōʻike

Ua ʻae ka Food and Drug Administration (FDA) iā Taltz e mālama:

  • kaulike a koʻikoʻi i ka lāʻau plake psoriasis i kūpono no ka systemic therapy a i ʻole phototherapy; no kēia hoʻohana, hiki ke kuhikuhi ʻia ka lāʻau no nā mākua a me nā keiki o nā makahiki 6 a ʻoi paha
  • ʻeleu psoriatic arthritis i nā mākua
  • non-radiographic axial spondyloarthritis (nr-axSpA) i nā mākua
  • ka ankylosing spondylitis (AS), kahi i kapa ʻia ʻo radiographic axial spondyloarthritis (r-axSpA); no kēia hoʻohana, hiki ke kuhikuhi ʻia ka lāʻau no nā mākua

Mekanism o ka hana

Aia ʻo Taltz i ka ixekizumab, kahi kanaka i loaʻa i ka IgG monoclonal antibody. Koho pono ʻia ʻo Ixekizumab a hoʻopaʻa iā interleukin-17A (IL-17A). ʻO IL-17A kekahi o nā cytokine hoʻowahāwahā i ʻike ʻia e pili ana i ka hana ʻana i nā pane kūpikipiki a me nā pale e kū ai i ka maʻi psoriatic a me ka spondylitis ankylosing. Ma ka hoʻopaʻa ʻana iā IL-17A, ua hoʻokau ʻo ixekizumab iā ia mai ka launa pū ʻana me ka receptor IL-17A a no laila ke kāohi nei i kēia mau pane.

Pharmacokinetics a me ka metabolism

ʻO ka biovailability Ixekizumab mai 60% a i 81% ma hope o ka hoʻopili ʻana o ka subcutaneus i loko o nā haʻawina psoriasis. Ua loaʻa ka bioavailability ʻoi aku ma o ka hoʻopili ʻana i ka ʻūhā ke hoʻohālikelike ʻia i nā pūnaewele ʻoki e like me ka lima a me ka ʻōpū.

ʻO ka hapalua o ke ola he 13 mau lā i nā kumuhana me ka psoriasis plake.

ʻAʻole i ʻike ʻia ke ala e hoʻopau ai i ka metabolic, akā manaʻo ʻia e like ia me ka endogenous IgG me nā ala catabolic e hana ana i nā peptides liʻiliʻi a me nā amino acid.

Nā Kūʻai Kūʻai

Hoʻohālikelike ʻia ʻo Taltz i ka poʻe me ka hopena hypersensitivity koʻikoʻi ma mua, e like me ka anaphylaxis, iā ixekizumab a i ʻole nā ​​mea i loaʻa iā ia.

Waihona

Pono e mālama ʻia ka Taltz autoinjector a me ka syringe prefilled i loko o ka pahu hau ma 36 ° F a 46 ° F (2 ° C a 8 ° C).

Mai paʻa hau. Palekana mai ka mālam. Mai hoʻoluliluli. Hiki ke mālama ʻia ʻo Taltz ma ke ana wela a hiki i 86 ° F (30 ° C) a i 5 mau lā. Ke mālama ʻia i ke ana wela, ʻaʻole pono e hoʻihoʻi ʻia i loko o ka pahu hau.

Hoʻolaha: Ua hana ʻo Nūhou Lapaʻau i kēia mau lā e hōʻoia i ka pololei, ka laulā, a me ka lā hou o nā ʻike āpau. Eia nō naʻe, ʻaʻole pono e hoʻohana i kēia ʻatikala i pani no ka ʻike a me ka mākaukau o kahi loea mālama ola laikini. E nīnau mau ʻoe i kāu kauka a i ʻole ʻoihana olakino ʻē aʻe ma mua o ka lawe ʻana i nā lāʻau. Hiki ke loli i ka ʻike o ka lāʻau i loko a ʻaʻole i manaʻo ʻia e uhi i nā hoʻohana a pau, nā kuhikuhi, ka mālama ʻana, nā ʻōlelo aʻoaʻo, nā launa lāʻau, nā hopena maʻi ʻaʻai, a me nā hopena maikaʻi ʻole. ʻO ka loaʻa ʻole o nā ʻōlelo aʻoaʻo a i ʻole nā ​​ʻike ʻē aʻe no kahi lāʻau i hāʻawi ʻia ʻaʻole ia e hōʻike i ka palekana o ka lāʻau a lāʻau paha i kūpono no nā mea maʻi āpau a i ʻole nā ​​hoʻohana kikoʻī āpau.

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