Soliqua 100/33 (insulin glargine / lixisenatide)

Anter

• He aha ka Soliqua 100/33?
• Ka hoʻokō ʻana
• Soliqua 100/33 generic
• ʻO Soliqua 100/33 mea hana
• Nā ʻano lāʻau a me nā ikaika
• Nā hana no Soliqua 100/33
• He aha inā e haʻo wau i kahi lāʻau?
• Pono wau e hoʻohana i kēia lāʻau lōʻihi?
• Nā hopena ʻaoʻao ʻo Soliqua 100/33
• Nā hopena ʻaoʻao hou aʻe
• Nā hopena hopena koʻikoʻi
• Soliqua 100/33 kāki
• Kōkua kālā a me nā ʻinikua
• Pehea e lawe ai iā Soliqua 100/33
• Pehea e lawelawe ai
• Manawa
• Lawe iā Soliqua 100/33 me ka meaʻai
• Nā koho ʻē aʻe iā Soliqua 100/33
• Soliqua 100/33 vs. Xultophy
• Hoʻohana
• Nā ʻano lāʻau a me ka hoʻoponopono ʻana
• Nā hopena a me nā pilikia
• Ka hoʻokō ʻana
• Nā kumukūʻai
• Soliqua 100/33 vs. nā lāʻau ʻē aʻe
• Soliqua 100/33 vs. Lantus
• Soliqua 100/33 vs. Victoza
• Soliqua 100/33 vs. Toujeo
• Soliqua 100/33 vs. Adlyxin
• Hoʻohana ʻo Soliqua 100/33
• Hoʻohana ʻo Soliqua 100/33 me nā lāʻau ʻē aʻe
• Soliqua 100/33 a me ka waiʻona
• Hana like ʻo Soliqua 100/33
• Soliqua 100/33 a me nā lāʻau ʻē aʻe
• Soliqua 100/33 a me nā mea kanu a me nā mea hoʻohui
• Pehea e hana ai ʻo Soliqua 100/33
• Pehea e pili ai ka insulin i ke kō kō
• He aha kā Soliqua 100/33 hana ai
• Pehea ka lōʻihi o ka hana?
• Soliqua 100/33 a me ka hāpai keiki
• Soliqua 100/33 a me ka waiū hānai
• Nā nīnau e pili ana iā Soliqua 100/33
• ʻO Soliqua 100/33 ke kumu o ka loaʻa ʻana o ke kaumaha?
• ʻO Soliqua 100/33 insulin?
• ʻO Soliqua 100/33 hana lōʻihi?
• Hiki iā Soliqua 100/33 ke hoʻohana e mālama i ka maʻi diabetes type 1?
• Nā ʻōlelo aʻoaʻo a Soliqua 100/33
• Soliqua 100/33 overdose
• Nā hōʻailona overdose
• He aha e hana ai inā he overdose
• Soliqua 100/33 pau a me kahi waiho
• ʻO ka ʻike ʻoihana no Soliqua 100/33
• Nā Hōʻike
• Mekanism o ka hana
• Pharmacokinetics a me ka metabolism
• Nā Kūʻai Kūʻai
• Waihona

He aha ka Soliqua 100/33?

ʻO Soliqua 100/33 kahi lāʻau lapaʻau inoa inoa inoa inoa. Hoʻohana ʻia me ka papaʻai a me ka hoʻoikaika kino e hoʻomaikaʻi ai i nā pae kō kō i nā mākua me ka maʻi diabetes type 2.

Loaʻa i loko o Soliqua 100/33 nā lāʻau ʻelua:

• insulin glargine, ʻo ia kahi insulina hana lōʻihi
• lixisenatide, no ka papa o nā lāʻau i kapa ʻia he like me ka peptide 1 (GLP-1)

Hele mai ʻo Soliqua 100/33 ma ke ʻano he peni hoʻokomo i hoʻohana ʻia no ka hoʻokomo ʻana iā ʻoe iho ma lalo o ka ʻili (subcutaneous). Loaʻa i kēlā me kēia peni ka 3 mL o ka hopena lāʻau, me nā 100 mau pūnaewele o ka insulin glargine a me 33 mcg o ka lixisenatide ma ka mL o ka hopena. Hoʻohana ʻia nā peni me nā nila kui, ʻaʻole i hoʻopili ʻia me nā peni.

Ka hoʻokō ʻana

Ua loaʻa ka maikaʻi o Soliqua 100/33 i ka mālama ʻana i ka maʻi diabetes type 2. I hoʻokahi hoʻokolohua hoʻokolohua, ua hoʻāʻo ʻia ʻo Soliqua 100/33 i ka poʻe me ka maʻi diabetes type 2 i mālama ʻia me nā insulins hana lōʻihi no ʻeono mahina. Ma hope o 30 mau pule o ka lapaʻau ʻana me Soliqua 100/33, ua hoʻemi kēia poʻe i ka hemoglobin A1c (HbA1c) e ka 1.1 pakeneka. Ua hoʻemi lākou i ka hoʻokē ʻai ʻana i nā kō a me ka 5.7 mg / dL.

Ma kahi noiʻi hoʻokolohua ʻē aʻe, ua hoʻohana ʻo Soliqua 100/33 me metformin no 30 mau pule. ʻO ka noiʻi e pili ana i ka poʻe i mālama mua ʻia me ka metformin wale nō, a i ʻole me ka metformin a me kahi lāʻau diabetes diabetes ʻē aʻe. ʻO ka mālama ʻana me Soliqua 100/33 a me metformin i hoʻemi ʻia ka HbA1c e 1.6 pakeneka. Ua hoʻemi ia i ka hoʻokēʻai ʻana i nā kō kō e ka 59.1 mg / dL.

Soliqua 100/33 generic

Loaʻa ʻo Soliqua 100/33 ma ke ʻano he lāʻau lapaʻau inoa. ʻAʻole i loaʻa i kēia manawa i ka palapala generic.

Loaʻa i loko o Soliqua 100/33 nā lāʻau lapaʻau ʻelua: ʻo ka insulin glargine a me ka lixisenatide. ʻAʻole loaʻa kekahi lāʻau i loko o kahi palapala laulā.

ʻO Insulin glargine kahi insulin lōʻihi lōʻihi e loaʻa ana nona iho e like me nā inoa inoa inoa e like me Lantus, Toujeo, a me Basaglar. Pili ʻo Lixisenatide i ka papa o nā lāʻau i kapa ʻia nā agonists reseptor 1 like like peptide 1 (GLP-1). Loaʻa ia e like me ka inoa inoa inoa Adlyxin.

ʻO Soliqua 100/33 mea hana

ʻO ka maʻamau, e hoʻomaka kāu kauka iā ʻoe ma kahi lāʻau haahaa o Soliqua 100/33 a hoʻomaʻamaʻa iā ia i ka manawa e kiʻi i ke ana i kūpono iā ʻoe. Kapa ʻia kēia hana hoʻoponopono i ka titration. E kauoha kauka loa i kāu kauka liʻiliʻi e hāʻawi i ka hopena i makemake ʻia.

Hōʻike ka ʻikepili aʻe i nā lāʻau i hoʻohana pinepine ʻia a koi ʻia paha. Eia nō naʻe, e mālama pono i nā lāʻau a ke kauka i kuhikuhi ai nāu. E hoʻoholo kāu kauka i ke ana ʻoi loa e kūpono i kāu mau pono.

Nā ʻano lāʻau a me nā ikaika

Kēlā pūʻolo o Soliqua 100/33 i loko o ʻelima mau disposable, prefilled Soliqua 100/33 i loko o nā peni i loko o ka pahu. ʻAʻole i hoʻokomo ʻia nā nila peni me nā peni. (I ka hapanui o nā hihia, hiki iā ʻoe ke kūʻai i nā nila peni ma kahi hale kūʻai lāʻau. Pono ʻoe i kahi kuhikuhi.)

Loaʻa i kēlā me kēia peni hoʻokomo ʻia 3 mL o ka hopena lāʻau, me ka huina o nā 300 unit o ka glargine insulin a me 100 mcg o ka lixisenatide.

ʻO ka Soliqua 100/33 peni peni i kēlā me kēia mea e hoʻohana ʻia i mau manawa. Hiki ke helu i nā manawa mai 5 a 20 mau manawa, ke kaukaʻi ʻia i kāu ana. Hiki ke hoʻohana ʻia kēlā me kēia peni a hiki i nā lā he 28 ma hope o ka hoʻohana mua. Ma hope o kēlā manawa, pono ʻoe e hoʻolei i ka peni, ʻoiai inā loaʻa kekahi o nā lāʻau.

Hoʻohana wale ʻia nā nila peni i hoʻokahi manawa i kēlā me kēia.

Nā hana no Soliqua 100/33

Hoʻonohonoho pinepine ʻia ʻo Soliqua 100/33 i nā injection hoʻokahi o 15 a 60 mau ʻāpana. ʻO ka huaʻōlelo ʻo “unit” ke ʻano o ke ana i hoʻohana ʻia no ka glargine insulin i loko o Soliqua 100/33. ʻO ka nui o ka mahele lāʻau no ka pahu kui he 60 mau pūnaewele, ʻo ia hoʻi he 60 mau ʻāpana o ka glargine insulin a me 20 mcg lixisenatide.

Ka hoʻomaka ʻana o nā ana

ʻO ka lāʻau hoʻomaka o Soliqua 100/33 i paipai ʻia e pili ana i kāu mālama maʻi diabetes mua.

Kaha: Ma mua o ka hoʻomaka ʻana iā Soliqua 100/33, pono ʻoe e hōʻoki i nā lāʻau ʻē aʻe āpau me ka lixisenatide a i ʻole ka insulin lōʻihi.

Laau mālama

Ma hope o ka hoʻomaka ʻana iā Soliqua 100/33, e nānā kāu kauka i kāu mau kō kō a hiki ke hoʻomaʻamaʻa i kāu mahele lāʻau e hiki i kāu kālā kūpono. Paipai ka mea hana o ka lāʻau lapaʻau i ka hoʻomaʻamaʻa ʻana i kahi lāʻau ma luna a i ʻole ma lalo o 2 a i 4 mau unit i kēlā me kēia pule e pono ai e kū i nā pahuhopu kō kō.

Hoʻololi hana

E hana pū ʻoe me kāu kauka e hana i kahi hoʻolālā e kū i kāu mau pahuhopu kō kō.

Aia ma lalo kahi laʻana o ka hoʻoponopono ʻana i ka lāʻau i koi ʻia e kāu kauka. E hoʻoholo kāu kauka inā pono ʻoe i kēia mau hoʻoponopono. E mālama pono i ka lāʻau i makemake ai kāu kauka. (Mai hoʻololi i kāu lāʻau me ka ʻole o ka ʻāpono a kāu kauka.)

He aha inā e haʻo wau i kahi lāʻau?

Inā ʻoe e nalo i kahi mahele o Soliqua 100/33, e lele i kēlā lāʻau a hoʻomau me kāu lāʻau i hoʻonohonoho ʻia e hiki mai ana. Mai hoʻāʻo e hopu i ka lawe ʻana i kahi lāʻau keu a i ʻole ka hoʻonui ʻana i ka lāʻau aʻe. Hiki i kēia ke kumu i nā hopena ʻino weliweli.

Pono wau e hoʻohana i kēia lāʻau lōʻihi?

Inā maikaʻi a palekana ʻo Soliqua 100/33 iā ʻoe, e hoʻohana paha ʻoe i kēia lāʻau lōʻihi. Hoʻohana pinepine ʻia ʻo Soliqua 100/33 i kahi manawa lōʻihi e mālama ai i ka maʻi kōpoki 2.

Nā hopena ʻaoʻao ʻo Soliqua 100/33

Hiki i ka Soliqua 100/33 ke hana i nā hopena ʻoluʻolu a koʻikoʻi paha. Loaʻa i ka papa inoa aʻe kekahi o nā hopena ʻē aʻe i hiki ke hana ʻia ke lawe nei iā Soliqua 100/33. ʻAʻole pili kēia papa inoa i nā hopena ʻaoʻao āpau.

No ka ʻike hou aku e pili ana i nā hopena ʻē aʻe o Soliqua 100/33, a i ʻole nā ​​ʻōlelo aʻoaʻo e pili ana i ka hana ʻana me ka hopena pilikia, e kamaʻilio me kāu kauka a kauka paha.

Nā hopena ʻaoʻao hou aʻe

ʻO nā hopena ʻaoʻao maʻamau o Soliqua 100/33 hiki ke hoʻopili ʻia:

• nausea
• nā maʻi hanu e like me ke anuanu a me ka flu
• pāhoehoe
• ʻeha poʻo
• hypoglycemia (haʻahaʻa kō kō)

E hala paha ka hapa nui o kēia mau hopena i loko o kekahi mau lā a i ʻole ʻelua mau pule. Inā ʻoi aku ke koʻikoʻi a i ʻole hele aku, e kamaʻilio me kāu kauka a kauka paha.

Nā hopena hopena koʻikoʻi

ʻO nā hopena koʻikoʻi koʻikoʻi mai Soliqua 100/33 ʻaʻole maʻamau, akā hiki ke hana ʻia. Kāhea koke i kāu kauka inā loaʻa nā hopena koʻikoʻi. Kāhea iā 911 inā manaʻo kou mau hōʻailona i ka hoʻoweliweli ola a i ʻole inā manaʻo ʻoe e loaʻa ana kahi pilikia olakino.

Hiki i nā hopena ʻē aʻe a me kā lākou mau hōʻailona ke hoʻohui i kēia:

• Kahi hopena maʻi ʻaʻano. Hiki i nā ʻōuli ke hoʻohui pū:
• hūwī
• ʻōpala
• pehu
• ʻili ʻili
• pilikia hanu
• haʻahaʻa haʻahaʻa haʻahaʻa
• Pancreatitis (pehu o ka pancreas). Hiki i nā ʻōuli ke hoʻohui pū:
• ʻeha a palupalu paha i loko o kou ʻōpū
• ʻeha kua
• nausea
• ka luaʻi
• fiva
• Kaumaha emi
• Poino hakuʻala. Hiki i nā ʻōuli ke hoʻohui pū:
• hoemi urination
• ka pehu ʻana i kou mau wāwae, nā kuʻekuʻe wāwae, a me nā wāwae
• huikau
• luhi
• nausea
• ʻeha ka umauma a i ʻole kaomi
• kuʻi naʻau kaulike ʻole
• ka hopu ʻana
• Hypokalemia (potassium haʻahaʻa). Hiki i nā ʻōuli ke hoʻohui pū:
• nāwaliwali
• luhi
• kōpaʻa
• ʻūpē mākala
• kuʻi naʻau kaulike ʻole

Loaʻa kaupaona a hōʻemi kino paha

I nā hoʻokolohua hoʻokolohua, ʻaʻole i loaʻa ʻo Soliqua 100/33 e hana i nā loli kaumaha. Eia nō naʻe, i loko o hoʻokahi hoʻokolohua hoʻokolohua, ʻo ka poʻe i lawe iā Soliqua 100/33 no 30 mau pule ua nalo e pili ana i 1.5 paona.

Hoʻohui ʻia, ua hoʻopili ʻia nā lāʻau ponoʻī i loko o Soliqua 100/33 me nā loli kaumaha. Loaʻa i ka Soliqua 100/33 ka insulin glargine, kahi insulin hana lōʻihi. Hiki i nā lāʻau i loko o ka insulin ke kumu i ka waiwai kaupaona.

Loaʻa iā Soliqua 100/33 ka lixisenatide, kahi like peptide 1 (GLP-1) agonist reseptor. I nā ʻano noiʻi like ʻole, ua hōʻike nā lāʻau i ka papa lāʻau ʻo GLP-1 i ka pohō kaumaha ma ke ʻano he ʻaoʻao.

Inā ʻoe hopohopo e pili ana i nā loli kaumaha i ka hoʻohana ʻana iā Soliqua 100/33, e kamaʻilio me kāu kauka.

Hypoglycemia

ʻO ka insulin, kekahi o nā lāʻau i Soliqua 100/33, hoʻohana ʻia e kōkua i ka hoʻohaʻahaʻa ʻana i nā pae kō kō. Eia nō naʻe, hiki i nā pae kō kō ke hoʻohaʻahaʻa ʻia i kahi mamao loa, kahi e hopena ai i ka hypoglycemia. ʻO ka hypoglycemia ka hopena maʻamau i hopena ʻia e nā lāʻau insulin, e like me Soliqua 100/33.

I nā noiʻi lapaʻau, ua loaʻa ka hypoglycemia ma 8.1 a 17.8 pakeneka o ka poʻe e lawe nei iā Soliqua 100/33. A kū ka hypoglycemia koʻikoʻi ma kahi o 1 ka pākēneka o ka poʻe e lawe nei i ka lāʻau.

Hiki i nā kumu he nui ke hoʻonui i kāu makaʻu o ka hypoglycemia. Hoʻopili kēia i ka lawe ʻana i nā lāʻau kiʻekiʻe o kāu lāʻau diabetes a me ka lawe ʻana ma mua o hoʻokahi lāʻau lāʻau diabetes. ʻO nā kumu ʻē aʻe e hiki ke hoʻopili i kāu makaʻu ʻo ia ka ʻai ʻana a me nā ʻano hoʻoikaika kino, a inā paha ʻoe e inu nei i nā lāʻau ʻē aʻe.

Kū koke nā ʻōuli o ka hypoglycemia a hiki ke hoʻopili ʻia me ka haʻalulu, ka luhi, ka hiamoe, a me ka huikau. Hiki i ka hypoglycemia koʻikoʻi ke alakaʻi i nā hopena ʻē aʻe e like me ka hopu ʻana a i ʻole ka make. E kamaʻilio me kāu kauka e pili ana i ka manawa pinepine e nānā ai i kāu pae kō kō e pale ai i ka hypoglycemia i ka lawe ʻana iā Soliqua 100/33.

Kaumaha a i ʻole ka ʻili manoanoa

Lawe ʻoe iā Soliqua 100/33 e ka injection subcutaneus, ʻo ia hoʻi ʻoe e hoʻokomo iā ia ma lalo o kou ʻili. Hiki i kahi ʻāpana subcutaneite ke kumu i ka lipodystrophy (kahi kaumaha a i ʻole ʻeleʻele o ka ʻili) a puni ka pūnaewele injection.

I mea e hōʻemi ai i ka makaʻu o ka lipodystrophy, e hoʻololi i nā pūnaewele kahi e hoʻopili ai i ka lāʻau. ʻO kahi laʻana, i kekahi lā hiki iā ʻoe ke hoʻokomo i ka lāʻau i loko o kou ʻōpū, a ʻo ka lā aʻe hiki iā ʻoe ke hoʻohana i kou ʻūhā waho.

Inā ʻoe hopohopo e pili ana i nā hopena ʻili i hoʻokumu ʻia e Soliqua 100/33, e kamaʻilio me kāu kauka.

Poino hakuʻala

ʻAʻole i ʻike ʻia ka hōʻino ʻana o nā hakuʻala i nā noiʻi maʻi o Soliqua 100/33. Eia nō naʻe, aia kekahi mau hōʻike e pili ana i ka hōʻino ʻana o ka hakuʻala i ka poʻe i mālama ʻia me nā lāʻau like peptide 1 (GLP-1) like me ka glucagon. ʻO Lixisenatide, ʻo ia kekahi o nā lāʻau i Soliqua 100/33, kahi lāʻau GLP-1.

Hiki i nā ʻōuli o ke kī hōʻino ke hoʻopili ʻia:

• ka pehu ʻana o nā wāwae, nā kuʻekuʻe wāwae, a me nā wāwae
• luhi
• nausea
• ka luaʻi

ʻO ka hōʻino ʻia o nā hakuʻala i hana pinepine ʻia i ka poʻe i make wai ʻole ma muli o kekahi mau hopena o Soliqua 100/33, e like me ka nausea, ka luaʻi, a me ka palahī.

Inā hoʻomohala ʻoe i kēia mau ʻōuli ke lawe nei iā Soliqua 100/33, a hopohopo paha e pili ana i kou olakino olakino, e kamaʻilio me kāu kauka.

Soliqua 100/33 kāki

E like me nā lāʻau āpau, hiki ke hoʻololi ke kumukūʻai o Soliqua 100/33.

E hilinaʻi kāu kumukūʻai maoli i kāu ʻinikua.

Kōkua kālā a me nā ʻinikua

Inā ʻoe e kākoʻo kālā e uku no Soliqua 100/33, loaʻa ke kōkua. ʻO Sanofi Aventis, ka mea hana o Soliqua 100/33, hāʻawi i kahi Kāleka Soliqua 100/33. No ka ʻike hou aku, e kipa i ka pūnaewele pūnaewele.

Pehea e lawe ai iā Soliqua 100/33

Ma lalo iho nei kekahi mau ʻōkuhi maʻamau e pili ana pehea e hāʻawi ai iā ʻoe iho i kahi injection e hoʻohana ana i ka peni Soliqua 100/33. E mālama pono iā Soliqua 100/33 e like me kāu ʻōlelo kauka a kauka paha.

Pehea e lawelawe ai

KaʻAnuʻu 1. Hoʻomākaukau a nānā i kāu peni.

Inā ʻo kēia kāu hoʻohana mua, e lawe i ka peni mai ka pahu hau a ʻae i ka peni e piʻi i ka mahana o ka lumi.

• E hōʻiliʻili i nā swab waiona, kahi nila hou, a me kāu ipu hoʻolei sharps.
• E holoi i kou mau lima.
• Wehe i ka pāpale peni a maopopo leʻa ka lāʻau a ʻaʻohe kala. (Mai hoʻohana inā ʻaʻole maopopo a kala ʻole ka hopena. Maikaʻi nā huʻa ea.)
• E hoʻomaʻemaʻe i ka sila kāpili me kahi wai ʻawa.

KaʻAnuʻu 2. Hoʻopili i kahi nila peni hou.

No kēlā me kēia kuʻi, e hoʻohana mau i kahi nila kuʻi. E nānā pono e hiki ke hoʻohana i ka nila kui me Soliqua 100/33. Inā ʻaʻole ʻoe e ʻike i nā nila e hoʻohana ai, e nīnau i kāu kauka a kauka paha.

• Wehe i ka nila peni mai kāna pūʻulu pale.
• Ke mālama pololei ʻana i ka nila o ka peni, wili iā ia ma ka peni.
• Wehe i ka pāpale kui kui waho a waiho ʻia. (E mālama iā ia no ka hoʻohana ma hope o ka pahu kui.)
• Wehe i ka pāpale kui kiki o loko a hoʻolei i loko o ka ʻōpala.

KaʻAnuʻu 3. Hana i kahi hōʻoia palekana.

E hana mau i kahi hōʻoia palekana ma mua o kēlā me kēia inikua e hōʻoia i ka hana pono ʻana o ka peni a me ka nila.

• Hoʻomaʻamaʻa i ka helu papahelu no laila heluhelu ia i 2 ʻāpana.
• Kaomi piha i ka pihi injection a nānā no kahi wahi o ka hopena lāʻau e puka mai ka piko o ka nila. Inā kū kēia, e hele i ka ʻanuʻu 4.
• Inā ʻaʻole puka mai kahi lāʻau, hana hou i ka hoʻāʻo palekana a hiki i nā manawa 3.
• Inā ʻaʻohe lāʻau e puka ma hope o ʻekolu mau hoʻokolohua, pani i ka nila a hana hou i nā hoʻāʻo palekana.
• Inā ʻaʻole puka mai kahi lāʻau i hope o ke kuapo ʻana i ka nila, mai hoʻohana i ka peni no ka mea e ʻino paha ia. E hoʻohana i kahi peni hou.

KaʻAnuʻu 4. Koho i kāu lāʻau.

• E hoʻohuli i ka hōʻaiho lāʻau a hiki i kāu kau lāʻau i kuhikuhi ʻia.

Pani 5. Hoʻokomo i ka lāʻau.

ʻEkolu mau wahi ma kou kino e hiki ai iā ʻoe ke hoʻohana no kahi pūnaewele injection: ʻo kou ʻōpū (koe wale nō ma loko o 2 ʻīniha o kou pihi ʻōpū), ke kua o kou lima luna (kahi momona), a me kou ʻūhā waho.

• Koho i kahi pūnaewele injection a holoi i ka ʻili ma ka pūnaewele me kahi swab alkohol.
• Ma ka pūnaewele injection, hoʻokomo i ka nila i kou ʻili ma ka ʻaoʻao 90-kekelē.
• E kaomi loa i ka pihi injection a paʻa a hiki i kou ʻike ʻana i kahi "0" i ka puka aniani.
• Ma hope o ka huli ʻana o ka hōʻaiʻē mahele lāʻau i "0," e helu i 10 ma mua o ka hoʻokuʻu ʻana i ke pihi hoʻokomo a lawe i ka nila. Kōkua kēia hoʻomaha iki i ka loaʻa ʻana o ka lāʻau piha.
• E hoʻokuʻu i ka pihi injection a hemo i ka nila mai kou ʻili.

KaʻAnuʻu 6. E hoʻolei i ka nila a mālama i ka peni.

• E hoʻihoʻi i ka pāpale pene peni waho i ka nila.
• Wehe i ka nila mai ka peni hoʻokomo a hoʻolei koke i ka nila i kahi pahu sharps. (E hoʻolei koke iā ia e pale i ka huikau me kahi nila hou.)
• E hoʻihoʻi i ka pāpale peni i luna o ka peni.
• E mālama i ka peni i ka mahana o ka lumi ma hope o ka hoʻohana mua.

Manawa

Lawe ʻoe iā Soliqua 100/33 i loko o ka hola ma mua o kāu pāʻina mua o ka lā.

Lawe iā Soliqua 100/33 me ka meaʻai

ʻAʻole pono e lawe ʻia ʻo Soliqua 100/33 me ka meaʻai. Lawe ʻia i loko o ka hola ma mua o kāu pāʻina mua o ka lā.

Nā koho ʻē aʻe iā Soliqua 100/33

Loaʻa nā lāʻau ʻē aʻe i hiki ke mālama i ka maʻi diabetes type 2. Kūpono paha kekahi iā ʻoe ma mua o nā poʻe ʻē aʻe. Inā makemake ʻoe i ka ʻimi ʻana i kahi ʻē aʻe iā Soliqua 100/33, e kamaʻilio me kāu kauka e aʻo hou e pili ana i nā lāʻau ʻē aʻe e holo pono paha iā ʻoe.

Loaʻa i loko o Soliqua 100/33 ʻelua mau lāʻau lapaʻau: kahi insulin lōʻihi hana ʻia i kapa ʻia ʻo insulin glargine, a me kahi peptide 1 (GLP-1) agonist reseptor i kapa ʻia lixisenatide.

ʻO nā laʻana o nā lāʻau e hiki ke hoʻohana ʻia ma ke ʻano he koho ʻē aʻe i Soliqua 100/33 me:

• nā insulins hana lōʻihi, e like me:
• insulin glargine (Lantus, Toujeo)
• insulin detemir (Levemir)
• ʻO nā agonists receptor GLP-1, e like me:
• exenatide (Bydureon, Byetta)
• liraglutide (Victoza, Sākona)
• lixisenatide (Adlyxin)
• semaglutide (Ozempic)
• dipeptidyl peptidase-4 (DPP-4) mea hoʻopukapuka, e like me:
• alogliptin (Nesina)
• linagliptin (Tradjenta)
• saxagliptin (Onglyza)
• sitagliptin (Januvia)
• meglitinides, e like me:
• repaglinide (Prandin)
• nateglinide (Starlix)
• metformin (Glucophage, Glumetza, Riomet)
• sodium-glucose cotransporter 2 (SGLT2) mea hoʻopukapuka, e like me:
• canagliflozin (Invokana)
• dapagliflozin (Farxiga)
• empagliflozin (Jardiance)
• sulfonylureas, e like me:
• glimepiride (Amaryl)
• glipizide (Glucotrol)
• glyburide (DiaBeta, Glynase)
• thiazolidinediones, e like me:
• pioglitazone (Actos)
• rosiglitazone (Avandia)

Soliqua 100/33 vs. Xultophy

Mahalo paha ʻoe pehea e hoʻohālikelike ai ʻo Soliqua 100/33 i nā lāʻau ʻē aʻe i kuhikuhi ʻia no nā hoʻohana like.Maanei mākou e nānā ai pehea e like ai a ʻokoʻa ai ʻo Soliqua 100/33 a me Xultophy.

Hoʻohana

Ua ʻae ʻia ʻo Soliqua 100/33 a me Xultophy e hoʻomaikaʻi i nā pae kō kō i nā mākua me ka maʻi diabetes type 2. Kauoha ʻia lāua ʻelua no ka hoʻohana me nā loliʻai a me ka hoʻoikaika kino.

Loaʻa i loko o Soliqua 100/33 a me Xultophy nā lāʻau ʻelua, a pili kēia mau lāʻau i nā papa like o ka lāʻau. ʻO ke kumu o ka hana like ʻana ma loko o ke kino.

Loaʻa iā Soliqua 100/33:

• insulin glargine (insulin hana lōʻihi)
• lixisenatide (like like me ka peptide glucagon-like 1 [GLP-1] agonist reseptor)

Loaʻa iā Xultophy:

• insulin degludec (insulin hana lōʻihi)
• liraglutide (GLP-1 receptor agonist)

Nā ʻano lāʻau a me ka hoʻoponopono ʻana

Hele mai ʻo Soliqua 100/33 a me Xultophy ma ke ʻano he wai hopena i loko o ka peni peni hoʻowali ʻole. Hoʻokomo ʻia ʻelua iā lākou iho ma lalo o ka ʻili (subcutaneous) hoʻokahi manawa i kēlā me kēia lā.

Nā hopena a me nā pilikia

Loaʻa nā hopena like o Soliqua 100/33 a me Xultophy i ke kino a no laila e like me nā hopena ʻaoʻao like loa.

Nā hopena ʻaoʻao hou aʻe

Aia i loko o kēia papa inoa nā laʻana o nā hopena ʻē aʻe i hiki ke hana ʻia me nā lāʻau ʻelua (ke lawe pākahi ʻia).

• Hiki ke hana me nā Soliqua 100/33 a me Xultophy:
• nā maʻi hanu e like me ke anuanu a me ka maʻi flu
• nausea
• pāhoehoe
• ʻeha poʻo
• hypoglycemia (haʻahaʻa kō kō)

Nā hopena hopena koʻikoʻi

Aia i loko o kēia mau papa inoa nā laʻana o nā hopena ʻino e hiki ke hana me Soliqua 100/33, me Xultophy, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).

• Hiki ke hana me Soliqua 100/33:
• kekahi mau hopena koʻikoʻi koʻikoʻi
• Hiki ke hana me Xultophy:
• maʻi ʻaʻai thyroid *
• maʻi maʻi pākī
• Hiki ke hana me nā Soliqua 100/33 a me Xultophy:
• hopena hopena maʻi ʻino
• hypoglycemia koʻikoʻi (kō kō kō ke kō.
• pancreatitis (li nui o ka pancreas)
• hōʻino kīhāpai
• hypokalemia (pae potassium haʻahaʻa)

* He ʻōlelo aʻoaʻo a Xultophy mai ka FDA no ka maʻi ʻaʻai thyroid. ʻO kahi ʻōlelo aʻoaʻo i pahu ʻia ka ʻōlelo aʻo ikaika a ka FDA e koi ai. Hoʻomaopopo ia i nā kauka a me nā mea maʻi e pili ana i nā hopena lāʻau e weliweli paha.

Ka hoʻokō ʻana

ʻAʻole hoʻohālikelike pololei ʻia ʻo Soliqua 100/33 a me Xultophy i nā noiʻi maʻi, akā ua loaʻa nā mea ʻelua i ka maikaʻi no ka mālama ʻana i ka maʻi maʻamau o 2.

I nā noiʻi ʻokoʻa, ua hoʻohana pono ʻo Soliqua 100/33 a me Xultophy i ka hōʻemi ʻana i nā HbA1c a me nā pae kō kō kō.

• I kahi noi hoʻokolohua, ua hoʻemi ʻo Soliqua 100/33 i ka hemoglobin A1c (HbA1c) e ka 1.1 pakeneka a me ka hoʻokēʻai ʻana i nā kō i ke kō e ka 5.7 mg / dL ma hope o 30 mau pule o ka lapaʻau.
• I nā noiʻi hoʻokolohua, hoʻemi ʻo Xultophy i ka HbA1c e 1.31 a i ka 1.94 pakeneka a me ka hoʻokē ʻai ʻana i nā pae kō kō e 49.9 mg / dL a 63.5 mg / dL ma hope o 26 mau pule o ka lapaʻau. Ua loaʻa ka poʻe e hoʻohana nei iā Xultophy ma kahi o 4.4 mau paona ma mua o 26 mau pule o ka mālama ʻana.

Kaha: He mea nui e hoʻomanaʻo i ka maikaʻi o kekahi o kēia mau lāʻau e hoʻohaʻahaʻa ai i kāu HbA1c a i ʻole ke kō ʻana o ke kō i ka nui o nā kumu, e like me:

• kou mau kō kō kō ke hoʻomaka ʻoe i ka lāʻau
• kāu papaʻai a me nā regimens hoʻoikaika kino
• nā lāʻau lapaʻau diabetes ʻē aʻe āu e lawe ai
• pehea kou ukali pono ʻana i kāu hoʻoponopono mālama

Nā kumukūʻai

ʻO Soliqua 100/33 a me Xultophy nā lāʻau lapaʻau inoa ʻelua. ʻAʻohe o nā ʻano laulā i loaʻa i kekahi lāʻau paha. ʻOi aku ke kumu kūʻai o nā lāʻau lapaʻau inoa inoa ma mua o nā generics.

Ma muli o nā koho mai GoodRx.com, ʻoi aku ke kumukūʻai o Xultophy ma mua o Soliqua 100/33. ʻO ke kumukūʻai maoli āu e uku ai no nā lāʻau ʻelua e pili ana i kāu lāʻau, kāu hoʻolālā ʻinikua, kou wahi, a me ka lāʻau kūʻai āu e hoʻohana ai.

Soliqua 100/33 vs. nā lāʻau ʻē aʻe

Aia kekahi mau lāʻau ʻē aʻe ma kahi o Soliqua 100/33 a me Xultophy (ma luna) hiki ke hoʻohana ʻia e mālama ai i ka maʻi kō ʻelua. Ma lalo nā hoʻohālikelike ma waena o Soliqua 100/33 a me nā lāʻau ʻē aʻe.

Soliqua 100/33 vs. Lantus

Loaʻa i loko o Soliqua 100/33 nā lāʻau ʻelua:

• insulin glargine, ʻo ia kahi insulina hana lōʻihi
• lixisenatide, no ka papa o nā lāʻau i kapa ʻia he like me ka peptide 1 (GLP-1)

ʻO ka insulin glargine ka lāʻau i loko o Lantus. Ma muli o ke kaʻanalike ʻana o Soliqua 100/33 a me Lantus i kahi mea hana, hana lākou i nā ʻano like i loko o ke kino.

Hoʻohana

Ua ʻae ʻia ʻo Soliqua 100/33 no ka hoʻohana me nā loliʻai a me ka hoʻoikaika kino e hoʻomaikaʻi ai i ke kiʻekiʻe o ke kō i nā mākua me ka maʻi diabetes type 2.

Ua ʻae ʻia ʻo Lantus e hoʻomaikaʻi i nā pae kō kō i nā mākua a me nā keiki i loaʻa i ka maʻi diabetes 1, a me nā mākua me ka maʻi kōkō 2.

Nā ʻano lāʻau a me ka hoʻoponopono ʻana

Hele mai ʻo Soliqua 100/33 ma ke ʻano he hopena wai i loko o ka peni hoʻokomo ʻino. Hele mai ʻo Lantus ma ke ʻano he hopena wai i loko o ka ipu kīʻaha he nui a i ʻole i kahi peni peni ʻino hiki ʻole. Hoʻopiʻi ʻia nā lāʻau ʻelua ma lalo o ka ʻili (subcutaneous) hoʻokahi no ka lā.

Nā hopena a me nā pilikia

Loaʻa i loko o Soliqua 100/33 a me Lantus nā insulina lōʻihi lōʻihi like, ʻo ka glargine insulin. No laila, hiki i nā lāʻau ʻelua ke hana i nā hopena ʻaoʻao like loa. Ma lalo nā hiʻohiʻona o kēia mau hopena ʻaoʻao.

Nā hopena ʻaoʻao hou aʻe

Aia i loko o kēia mau papa inoa nā laʻana o nā hopena ʻē aʻe i hiki ke hana ʻia me Soliqua 100/33, me Lantus, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).

• Hiki ke hana me Soliqua 100/33:
  • nausea
  • nā maʻi hanu e like me ke anuanu a me ka maʻi flu
  • ʻeha poʻo
  • pāhoehoe
• Hiki ke hana me Lantus:
  • loaʻa kaupaona
  • lipodystrophy (indentation a i ʻole ʻānoanoa o ka ʻili ma kahi pūnaewele injection)
  • nā hopena kahua pūnaewele injection
• Hiki ke hana me Soliqua 100/33 a me Lantus:
  • hypoglycemia (haʻahaʻa kō kō)

Nā hopena hopena koʻikoʻi

Loaʻa i kēia mau papa inoa nā laʻana o nā hopena ʻino e hiki ke hana me Soliqua 100/33, me Lantus, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).

• Hiki ke hana me Soliqua 100/33:
  • pancreatitis (li nui o ka pancreas)
  • hōʻino kīhāpai
• Hiki ke hana me Lantus:
  • kekahi mau hopena koʻikoʻi koʻikoʻi
• Hiki ke hana me Soliqua 100/33 a me Lantus:
  • hopena hopena maʻi ʻino
  • hypoglycemia koʻikoʻi (kō kō kō ke kō.
  • nā pae potassium haʻahaʻa (hypokalemia)

Ka hoʻokō ʻana

Hoʻohālikelike ka maikaʻi o Soliqua 100/33 a me Lantus i loko o ʻelua mau noiʻi. I ke aʻo mua, hoʻohana hoʻokahi ʻia nā lāʻau ʻelua. I ka lua, ua hoʻohana ʻia kēlā me kēia me ka metformin (kahi lāʻau diabetes diabetes).

Hoʻohana wale

ʻO ka loiloi mua i kau ʻia i nā mākua me ka maʻi diabetes ʻano 2 i mālama ʻia ma mua me nā insulins hana lōʻihi. Ua hōʻike ʻia e ʻoi aku ka maikaʻi o ka ʻoi aku o Soliqua 100/33 ma mua o Lantus no ka hoʻemi ʻana i ka hemoglobin A1c (HbA1c), akā ʻaʻole maikaʻi pū me ka hoʻēmi ʻana i nā pae kō kō.

Ma hope o 30 mau pule o ka hoʻomaʻamaʻa ʻana, hoʻemi ʻo Soliqua 100/33 i ka HbA1c e ka 1.1 pakeneka, a me ka hoʻokē ʻai ʻana i nā pae kō kō e 5.7 mg / dL. I loko o ka manawa like, hoʻemi ʻo Lantus iā HbA1c e 0.6 pakeneka, a me ka hoʻokē ʻai ʻana i nā pae kō kō e 7.0 mg / dL.

Hoʻohana me ka metformin

Ua hoʻāʻo ka lua o ka noiʻi iā Soliqua 100/33 me ka metformin e kūʻē iā Lantus me ka metformin i nā mākua me ka maʻi kōkō 2. Ua mālama mua ʻia kēia poʻe me ka metformin wale nō, a i ʻole me ka metformin a me kahi lāʻau mimikō waha ʻē aʻe.

Ma kahi o 30 mau pule, ʻoi aku ka maikaʻi o Soliqua 100/33 me ka metformin ma mua o Lantus me ka metformin. Ua hoʻemi ʻo Soliqua 100/33 me metformin i ka HbA1c e 1.6 pakeneka a me ka hoʻokē ʻai ʻana i nā kō i ke kō e 59.1 mg / dL. ʻO Lantus a me metformin, ma ka ʻaoʻao ʻē aʻe, ua hoʻemi i ka HbA1c e ka 1.3 pakeneka a me ka hoʻokē ʻai ʻana i nā kō i ke kō i hoʻoliʻiliʻi ʻia e 55.8 mg / dL.

Kaha: He mea nui e hoʻomanaʻo i ka maikaʻi o kekahi o kēia mau lāʻau e hoʻohaʻahaʻa ai i kāu HbA1c a i ʻole nā ​​kō kō kō e pili i nā kumu he nui, e like me:

• kou mau kō kō kō ke hoʻomaka ʻoe i ka lāʻau
• kāu papaʻai a me nā regimens hoʻoikaika kino
• nā lāʻau lapaʻau diabetes ʻē aʻe āu e lawe ai
• pehea kou ukali pono ʻana i kāu hoʻoponopono mālama

Nā kumukūʻai

ʻO Soliqua 100/33 a me Lantus nā lāʻau lapaʻau inoa ʻelua. ʻAʻohe o nā ʻano laulā i loaʻa i kekahi lāʻau paha. ʻOi aku ke kumu kūʻai o nā lāʻau lapaʻau inoa inoa ma mua o nā generics.

Wahi a nā koho mai GoodRx.com, ʻoi aku ka uku o Lantus ma mua o Soliqua 100/33. ʻO ke kumukūʻai maoli āu e uku ai no nā lāʻau ʻelua e pili ana i kāu lāʻau, kāu hoʻolālā ʻinikua, kou wahi, a me ka lāʻau kūʻai āu e hoʻohana ai.

Soliqua 100/33 vs. Victoza

Loaʻa i loko o Soliqua 100/33 nā lāʻau ʻelua:

• insulin glargine, ʻo ia kahi insulina hana lōʻihi
• lixisenatide, no ka papa o nā lāʻau i kapa ʻia he like me ka peptide 1 (GLP-1)

Aia i loko o Victoza ka lāʻau liraglutide, ʻo ia hoʻi kahi agonist receptor GLP-1. Ma muli o ke kaʻanalike ʻana o Soliqua 100/33 a me Victoza i kahi mea hana i ka papa lāʻau like, hana lākou i nā ʻano like i loko o ke kino.

Hoʻohana

Ua ʻae ʻia ʻo Soliqua 100/33 e hoʻomaikaʻi i nā pae kō kō i nā mākua me ka maʻi diabetes type 2. Kauoha ʻia ia e hoʻohana me nā loliʻai a me ka hoʻoikaika kino.

Ua ʻae ʻia ʻo Victoza e hoʻomaikaʻi i nā pae kō kō i nā mākua me ka maʻi diabetes ʻano 2 me ka hoʻomaikaʻi ʻana i ka papaʻai a me ka hoʻoikaika kino. Hoʻohui ʻia, ʻae ʻia e hōʻemi i ka pilikia o nā pilikia puʻuwai nui e like me ka puʻuwai puʻuwai a me ka hahau ʻana i ka poʻe me ka maʻi diabetes type 2 a me nā maʻi puʻuwai.

Nā ʻano lāʻau a me ka hoʻoponopono ʻana

Hele mai ʻo Soliqua 100/33 a me Victoza ma ke ʻano he hopena wai i loko o ka peni hoʻokomo ʻino ʻole. Hoʻopiʻi pono ʻia nā lāʻau ʻelua ma lalo o ka ʻili (subcutaneous) hoʻokahi no ka lā.

Nā hopena a me nā pilikia

Ma muli o Soliqua 100/33 a me Victoza i loaʻa i ka lāʻau i pili i ka papa lāʻau lāʻau GLP-1, hiki i nā lāʻau ʻelua ke hana i nā hopena ʻaoʻao like loa. Ma lalo nā hiʻohiʻona o kēia mau hopena ʻaoʻao.

Nā hopena ʻaoʻao hou aʻe

Aia i loko o kēia mau papa inoa nā laʻana o nā hopena ʻaoʻao maʻamau e hiki ke hana me Soliqua 100/33, me Victoza, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).

• Hiki ke hana me Soliqua 100/33:
  • hypoglycemia (haʻahaʻa kō kō)
  • nā maʻi hanu e like me ke anuanu a me ka flu
  • ʻeha poʻo
• Hiki ke hana me Victoza:
  • hoʻēmi ʻai
  • ka luaʻi
  • kōpaʻa
  • huhū ka ʻōpū
• Hiki ke hana me nā Soliqua 100/33 a me Victoza:
  • nausea
  • pāhoehoe

Nā hopena hopena koʻikoʻi

Aia i loko o kēia mau papa inoa nā laʻana o nā hopena ʻino e hiki ke hana me Soliqua 100/33, me Victoza, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).

• Hiki ke hana me Soliqua 100/33:
  • hypokalemia (pae potassium haʻahaʻa)
• Hiki ke hana me Victoza:
  • maʻi ʻaʻai thyroid *
  • maʻi maʻi pākī
• Hiki ke hana me Soliqua 100/33 a me Victoza:
  • hopena hopena maʻi ʻino
  • hypoglycemia koʻikoʻi (kō kō kō ke kō.
  • pancreatitis (li nui o ka pancreas)
  • hōʻino kīhāpai

* He ʻōlelo aʻoaʻo a Victoza mai ka FDA no ka maʻi ʻaʻai thyroid. ʻO kahi ʻōlelo aʻoaʻo i pahu ʻia ka ʻōlelo aʻo ikaika a ka FDA e koi ai. Hoʻomaopopo ia i nā kauka a me nā mea maʻi e pili ana i nā hopena lāʻau e weliweli paha.

Ka hoʻokō ʻana

ʻAʻole hoʻohālikelike pololei ʻia ʻo Soliqua 100/33 a me Victoza i loko o nā noiʻi haukapila, akā ua loaʻa nā mea ʻelua i ka maikaʻi no ka mālama ʻana i ka maʻi diabetes type 2.

I nā noiʻi ʻokoʻa, ua hoʻohaʻahaʻa nā Soliqua 100/33 a me Victoza i ka HbA1c a me ka hoʻokē ʻai ʻana i nā pae kō kō i nā poʻe me ka maʻi diabetes 2.

• I kahi hoʻokolohua hoʻokolohua, ma hope o 30 mau pule o ka mālama ʻana, ua hoʻemi ʻo Soliqua 100/33 i ka hemoglobin A1c (HbA1c) e ka 1.1 pakeneka a me ka hoʻokē ʻai ʻana i nā pae kō kō e 5.7 mg / dL.
• I nā noiʻi hoʻokolohua ʻē aʻe, ma kahi o 52 mau pule o ka mālama ʻana, ua hoʻemi ʻo Victoza iā HbA1c ma kahi o 0.8 a 1.1 pākēneka a me ka hoʻokē ʻai ʻana i nā pae kō kō e 15 a 26 mg / dL.

Ua hōʻike ʻia kahi noiʻi lapaʻau ʻokoʻa i hōʻemi ʻo Victoza i ka pilikia o nā pilikia puʻuwai nui e like me ka hōʻeha puʻuwai a me ka hahau ʻana e 13 pākēneka. ʻAʻole i aʻo ʻia kēia hopena i ka noiʻi ʻana ma Soliqua 100/33.

Kaha: He mea nui e hoʻomanaʻo i ka maikaʻi o kekahi o kēia mau lāʻau e hoʻohaʻahaʻa ai i kāu HbA1c a i ʻole ke kō i ke kō i ka nui o nā kumu, e like me:

• kou mau kō kō kō ke hoʻomaka ʻoe i ka lāʻau
• kāu papaʻai a me nā regimens hoʻoikaika kino
• nā lāʻau lapaʻau diabetes ʻē aʻe āu e lawe ai
• pehea kou ukali pono ʻana i kāu hoʻoponopono mālama

Nā kumukūʻai

ʻO Soliqua 100/33 lāua ʻo Victoza nā lāʻau lapaʻau inoa ʻelua. ʻAʻohe o nā ʻano laulā i loaʻa i kekahi lāʻau paha. ʻOi aku ke kumu kūʻai o nā lāʻau lapaʻau inoa inoa ma mua o nā generics.

Wahi a nā koho mai GoodRx.com, ʻoi aku ka uku o Victoza ma mua o Soliqua 100/33. ʻO ke kumukūʻai maoli āu e uku ai no kēlā me kēia lāʻau e pili ana i kāu hana, kāu hoʻolālā ʻinikua, kou wahi, a me ka lāʻau kūʻai āu e hoʻohana ai.

Soliqua 100/33 vs. Toujeo

Loaʻa i loko o Soliqua 100/33 nā lāʻau ʻelua:

• insulin glargine, ʻo ia kahi insulina hana lōʻihi
• lixisenatide, no ka papa o nā lāʻau i kapa ʻia he like me ka peptide 1 (GLP-1)

ʻO ka insulin glargine ka lāʻau i loko o Toujeo. Ma muli o ke kaʻanalike ʻana o Soliqua 100/33 a me Toujeo i kahi mea hana, hana lākou i nā ʻano like i loko o ke kino.

Hoʻohana

Ua ʻae ʻia ʻo Soliqua 100/33 e hoʻomaikaʻi i nā pae kō kō i nā mākua me ka maʻi diabetes 2. Ua ʻae ʻia no ka hoʻohana me nā hoʻololi o ka papaʻai a me ka hoʻoikaika kino.

Ua ʻae ʻia ʻo Toujeo e hoʻomaikaʻi i nā pae kō kō i nā poʻe mākua me ka maʻi kōkō 2, a me nā mākua a me nā keiki me ka maʻi diabetes type 1.

Nā ʻano lāʻau a me ka hoʻoponopono ʻana

Hele mai ʻo Soliqua 100/33 a me Toujeo ma ke ʻano he hopena wai i kahi peni hoʻokomo Hoʻopiʻi ʻia nā lāʻau ʻelua ma lalo o ka ʻili (subcutaneous) hoʻokahi no ka lā.

Hele mai ʻo Soliqua 100/33 i hoʻokahi nui. Loaʻa i kēlā me kēia peni ka 3 mL o ka hopena lāʻau, me nā 300 pūʻulu o ka insulin glargine a me 100 mcg o ka lixisenatide. ʻO ka nui o ka mahele lāʻau no ka pahu kui he 60 mau pūnaewele, ʻo ia hoʻi he 60 mau ʻāpana o ka glargine insulin a me 20 mcg lixisenatide.

Hele mai ʻo Toujeo i ʻelua mau kālā ʻokoʻa:

• ʻO Toujeo SoloStar loaʻa nā huahelu 450 o ka glargine insulin i 1.5 mL o ka hopena, me kahi mahele lāʻau he 80 o nā anakahi no ka injection.
• ʻO Toujeo Max SoloStar Loaʻa nā 900 ʻāpana o ka glargine insulin i 3 mL o ka hopena, me kahi mahele lāʻau o 160 mau huahelu no ka pahu kui.

Nā hopena a me nā pilikia

Māhele like ʻo Soliqua 100/33 a me Toujeo i ka insulin hana lōʻihi like ʻole, ka insulin glargine. No laila, hiki i nā lāʻau ʻelua ke hana i nā hopena ʻaoʻao like loa. Ma lalo nā hiʻohiʻona o kēia mau hopena ʻaoʻao.

Nā hopena ʻaoʻao hou aʻe

Aia i loko o kēia mau papa inoa nā laʻana o nā hopena ʻino e hiki ke loaʻa me Soliqua 100/33, me Toujeo, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).

• Hiki ke hana me Soliqua 100/33:
  • nausea
  • pāhoehoe
  • ʻeha poʻo
• Hiki ke hana me Toujeo:
  • loaʻa kaupaona
  • nā hopena kahua pūnaewele injection
  • lipodystrophy (indentation a i ʻole kaumaha i kahi o ka injection)
  • ʻumeʻume
  • hūwī
  • ka pehu ʻana i kou mau wāwae, nā kuʻekuʻe wāwae, a me nā wāwae
• Hiki ke hana me Soliqua 100/33 a me Toujeo:
  • nā maʻi hanu e like me ke anuanu a me ka flu
  • hypoglycemia (haʻahaʻa kō kō)

Nā hopena hopena koʻikoʻi

Loaʻa i kēia mau papa inoa nā laʻana o nā hopena ʻino e hiki ke hana me Soliqua 100/33, me Toujeo, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).

• Hiki ke hana me Soliqua 100/33:
  • pancreatitis (li nui o ka pancreas)
  • hōʻino kīhāpai
• Hiki ke hana me Toujeo:
  • kekahi mau hopena koʻikoʻi koʻikoʻi
• Hiki ke hana me Soliqua 100/33 a me Toujeo:
  • hopena hopena maʻi ʻino
  • hypoglycemia koʻikoʻi (kō kō kō ke kō.
  • hypokalemia (pae potassium haʻahaʻa)

Ka hoʻokō ʻana

ʻAʻole hoʻohālikelike pololei ʻo Soliqua 100/33 a me Toujeo i nā noiʻi maʻi. Eia nō naʻe, ua hōʻike ʻia nā noiʻi pākahi e hiki ke hoʻohana pono ʻia nā Toujeo a me Soliqua 100/33 i ka hōʻemi ʻana i nā HbA1c a me nā pae kō kō kō.

• I kahi noiʻi hoʻokolohua, ua hoʻemi ʻo Soliqua 100/33 i ka hemoglobin A1c (HbA1c) e ka 1.1 pakeneka a me ka hoʻokēʻai ʻana i nā kō i ke kō e ka 5.7 mg / dL ma hope o 30 mau pule o ka lapaʻau.
• I nā noiʻi hoʻokolohua ʻē aʻe, ua hoʻemi ʻo Toujeo i ka HbA1c ma kahi o 0.73 a 1.42 pakeneka a me ka hoʻokē ʻai ʻana i nā pae kō kō e 18 a 61 mg / dL ma mua o 26 mau pule o ka lapaʻau.

Kaha: He mea nui e hoʻomanaʻo i ka maikaʻi o kekahi o kēia mau lāʻau e hoʻohaʻahaʻa ai i kāu HbA1c a i ʻole ke kō ʻana o ke kō i ka nui o nā kumu, e like me:

• kou mau kō kō kō ke hoʻomaka ʻoe i ka lāʻau
• kāu papaʻai a me nā regimens hoʻoikaika kino
• nā lāʻau lapaʻau diabetes ʻē aʻe āu e lawe ai
• pehea kou ukali pono ʻana i kāu hoʻoponopono mālama

Nā kumukūʻai

ʻO Soliqua 100/33 a me Toujeo nā lāʻau lapaʻau inoa ʻelua. ʻAʻohe o nā ʻano laulā i loaʻa i kekahi lāʻau paha. ʻOi aku ke kumu kūʻai o nā lāʻau lapaʻau inoa inoa ma mua o nā generics.

Wahi a nā koho mai GoodRx.com, ʻoi aku ke kumukūʻai ʻo Toujeo ma mua o Soliqua 100/33. ʻO ke kumukūʻai maoli āu e uku ai no nā lāʻau ʻelua e pili ana i kāu lāʻau, kāu hoʻolālā ʻinikua, kou wahi, a me ka lāʻau kūʻai āu e hoʻohana ai.

Soliqua 100/33 vs. Adlyxin

Loaʻa i loko o Soliqua 100/33 nā lāʻau ʻelua:

• insulin glargine, ʻo ia kahi insulina hana lōʻihi
• lixisenatide, no ka papa o nā lāʻau i kapa ʻia he like me ka peptide 1 (GLP-1)

ʻO Lixisenatide kekahi lāʻau i loko o Adlyxin. Ma muli o ke kaʻanalike ʻana o Soliqua 100/33 a me Adlyxin i kahi mea hana, hana lākou i nā ʻano like i ke kino.

Hoʻohana

Ua ʻae ʻia ʻo Soliqua 100/33 no ka hoʻohana me nā loliʻai a me ka hoʻoikaika kino e hoʻomaikaʻi ai i nā pae kō kō i nā mākua me ka maʻi kōkō 2.

Ua ʻae ʻia ʻo Adlyxin no ka hoʻohana ʻana me ka papaʻai a me ka hoʻoikaika kino e hoʻomaikaʻi ai i nā pae kō kō i nā mākua me ka maʻi diabetes type 2.

Nā ʻano lāʻau a me ka hoʻoponopono ʻana

Hele mai ʻo Soliqua 100/33 a me Adlyxin ma ke ʻano he hopena wai i kahi peni hoʻokomo Hoʻopiʻi pono ʻia nā lāʻau ʻelua ma lalo o ka ʻili (subcutaneous) hoʻokahi no ka lā.

Hele mai ka peni Soliqua 100/33 i hoʻokahi nui. Loaʻa i kēlā me kēia peni ka 3 mL o ka hopena lāʻau, me 100 mau hua o ka glargine insulin a me 33 mcg o ka lixisenatide ma ka mL. ʻO ka nui o ka mahele lāʻau no ka pahu kui he 60 mau pūnaewele, ʻo ia hoʻi he 60 mau ʻāpana o ka glargine insulin a me 20 mcg lixisenatide.

Hele mai ka pen Adlyxin i ʻelua mau helu ʻokoʻa:

• Loaʻa i ka pen Adlyxin ʻōmaʻomaʻo 50 mcg / mL i 3 mL o ka hopena, me kahi mahele lāʻau o 10 mcg no ke kīkī.
• Loaʻa ka peni burgundy Adlyxin i ka 100 mcg / mL i 3 mL o ka hopena, me kahi mahele o 20 mcg no ka pahu kui.

Nā hopena a me nā pilikia

Loaʻa iā Soliqua 100/33 a me Adlyxin ka lāʻau lixisenatide. No laila, hiki i nā lāʻau ʻelua ke hana i nā hopena ʻaoʻao like loa. Ma lalo nā hiʻohiʻona o kēia mau hopena ʻaoʻao.

Nā hopena ʻaoʻao hou aʻe

Aia i loko o kēia mau papa inoa nā laʻana o nā hopena ʻaoʻao maʻamau e hiki ke hana me Soliqua 100/33, me Adlyxin, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).

• Hiki ke hana me Soliqua 100/33:
  • nā maʻi hanu e like me ke anuanu a me ka maʻi flu
• Hiki ke hana me Adlyxin:
  • ka luaʻi
  • ʻūpā
• Hiki ke hana me Soliqua 100/33 a me Adlyxin:
  • nausea
  • pāhoehoe
  • ʻeha poʻo
  • hypoglycemia (haʻahaʻa kō kō)

Nā hopena hopena koʻikoʻi

Loaʻa i kēia mau papa inoa nā laʻana o nā hopena ʻino e hiki ke hana me Soliqua 100/33, me Adlyxin, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).

• Hiki ke hana me Soliqua 100/33:
  • hypokalemia (pae potassium haʻahaʻa)
• Hiki ke hana me Adlyxin:
  • kekahi mau hopena koʻikoʻi koʻikoʻi
• Hiki ke hana me Soliqua 100/33 a me Adlyxin:
  • hopena hopena maʻi ʻino
  • hypoglycemia koʻikoʻi (kō kō kō ke kō.
  • pancreatitis (li nui o ka pancreas)
  • hōʻino kīhāpai

Ka hoʻokō ʻana

ʻO ka hoʻohana ʻana o Soliqua 100/33 a i ʻole Adlyxin ma ke ʻano he lāʻau lapaʻau hoʻokahi no ka maʻi diabetes type 2 ʻaʻole i hoʻohālikelike ʻia i ka noiʻi noiʻi.Eia nō naʻe, ua hoʻohālikelike ʻia ka hoʻohana ʻana o kēlā me kēia lāʻau i ka hui pū ʻana me ka metformin (kahi lāʻau diabetes diabetes).

Hoʻokaʻawale i nā aʻo ke hoʻohana wale ʻia

I nā noiʻi hoʻokolohua ʻokoʻa, ʻo Soliqua 100/33 a me Adlyxin ka mea hoʻokahi i ka hoʻemi ʻana i ke kō i ke kō kō i kēlā me nā maʻi diabetes 2.

• I kahi noiʻi hoʻokolohua, ua hoʻemi ʻo Soliqua 100/33 i ka hemoglobin A1c (HbA1c) e ka 1.1 pakeneka a me ka hoʻokēʻai ʻana i nā kō i ke kō e ka 5.7 mg / dL ma hope o 30 mau pule o ka lapaʻau.
• I kahi noiʻi hoʻokolohua ʻokoʻa, ua hoʻemi ʻo Adlyxin i ka HbA1c e 0.57 i ka 0.71 pakeneka a me ka hoʻokē ʻai ʻana i nā pae kō kō e 4.48 a 24.56 mg / dL ma mua o 24 mau pule o ka lapaʻau.

Hoʻohālikelike pololei ke hoʻohana ʻia me metformin

Ua hoʻāʻo kahi noiʻi ʻē aʻe i ka hoʻohana ʻana o Soliqua 100/33 me ka metformin kūʻē i ka hoʻohana ʻana o Adlyxin me ka metformin i nā mākua me ka maʻi kōkō 2. Ua mālama mua ʻia ka poʻe i ke aʻo ʻana me ka metformin wale nō, a i ʻole me ka metformin a me kahi lāʻau diabetes diabetes ʻē aʻe.

Ma hope o 30 mau pule, ʻoi aku ka maikaʻi o Soliqua 100/33 me ka metformin ma mua o Adlyxin me ka metformin. Ua hoʻemi ʻo Soliqua 100/33 me metformin i ka HbA1c e 1.6 pakeneka a me ka hoʻokē ʻai ʻana i nā kō i ke kō e 59.1 mg / dL. ʻO Adlyxin a me metformin, ma ka ʻaoʻao ʻē aʻe, ua hoʻemi i ka HbA1c e 0.9 pakeneka a me ka hoʻokē ʻai ʻana i nā pae kō kō e 27.2 mg / dL.

Kaha: He mea nui e hoʻomanaʻo i ka maikaʻi o kekahi o kēia mau lāʻau e hoʻohaʻahaʻa ai i kāu HbA1c a i ʻole nā ​​kō kō kō e pili i nā kumu he nui, e like me:

• kou mau kō kō kō ke hoʻomaka ʻoe i ka lāʻau
• kāu papaʻai a me nā regimens hoʻoikaika kino
• nā lāʻau lapaʻau diabetes ʻē aʻe āu e lawe ai
• pehea kou ukali pono ʻana i kāu hoʻoponopono mālama

Nā kumukūʻai

ʻO Soliqua 100/33 a me Adlyxin nā lāʻau lapaʻau inoa ʻelua. ʻAʻohe o nā ʻano laulā i loaʻa i kekahi lāʻau paha. ʻOi aku ke kumu kūʻai o nā lāʻau lapaʻau inoa inoa ma mua o nā generics.

Wahi a nā koho mai GoodRx.com, ʻoi aku ke kumukūʻai ʻo Adlyxin ma mua o Soliqua 100/33. ʻO ke kumukūʻai maoli āu e uku ai no nā lāʻau ʻelua e pili ana i kāu hana, kāu hoʻolālā ʻinikua, kou wahi, a me ka lāʻau kūʻai āu e hoʻohana ai.

I ka Mei 2020, ua kuhikuhi ka Food and Drug Administration (FDA) i kekahi mau mea hana metformin hoʻolōʻihi ʻia e wehe i kekahi o kā lākou papa mai ka mākeke U.S. ʻO kēia no ka mea he pae i ʻae ʻole ʻia o kahi carcinogen probable (ʻākena e hana ana i ka maʻi ʻaʻai) i loaʻa i kekahi mau papa metformin hoʻolōʻihi ʻia. Inā lawe ʻoe i kēia lāʻau i kēia manawa, e kāhea i kāu kauka. E ʻōlelo aʻoaʻo lākou inā ʻoe e hoʻomau i ka lawe ʻana i kāu lāʻau a i ʻole inā makemake ʻoe i kahi palapala hou.

Hoʻohana ʻo Soliqua 100/33

Ua ʻae ka Food and Drug Administration (FDA) i nā lāʻau i kuhikuhi ʻia e like me Soliqua 100/33 e mālama i kekahi mau ʻano. Ua ʻae ʻia ʻo Soliqua 100/33 no ka hoʻohana me nā loliʻai a me ka hoʻoikaika kino e hoʻomaikaʻi ai i nā pae kō kō i nā mākua me ka maʻi kōkō 2.

I loko o kahi hoʻokolohua hoʻokolohua 30 hebedoma o ka poʻe i mālama ʻia me kahi ʻano o ka basal insulin (e like me ka insulin glargine), ua loaʻa he maikaʻi ʻo Soliqua 100/33. Ua hoʻemi ia ka hemoglobin A1c (HbA1c) e ka 1.1 pakeneka a me ka hoʻokē ʻai ʻana i nā pae kō kō e 5.7 mg / dL.

Ua hoʻopaʻa ʻia kahi noiʻi haukapila he 30 mau pule i ka poʻe i mālama ʻia me ka metformin wale nō, a i ʻole me metformin a me kahi lāʻau diabetis waha ʻē aʻe. No ka poʻe i ke aʻo ʻana, ua hoʻemi ʻo Soliqua 100/33 a me metformin i ko lākou HbA1c e 1.6 pakeneka a me ka hoʻokē ʻai ʻana i nā kō i ke kō e 59.1 mg / dL.

Hoʻohana ʻo Soliqua 100/33 me nā lāʻau ʻē aʻe

Hiki ke hoʻohana wale ʻia ʻo Soliqua 100/33 a i ʻole hui pū ʻia me nā lāʻau ʻē aʻe e hoʻomaikaʻi i nā pae kō kō i nā poʻe me ka maʻi diabetes 2. I ka mālama ʻana i ka maʻi diabetes, he mea maʻamau ia no nā mea ʻoi aku ma mua o hoʻokahi lāʻau e hoʻohana ai e kaohi i nā pae kō kō inā ʻaʻole i hoʻomaikaʻi maikaʻi kahi lāʻau wale nō.

Nā laʻana o nā lāʻau i hiki ke hoʻohana ʻia me Soliqua 100/33 me:

• canagliflozin (Invokana)
• dapagliflozin (Farxiga)
• glimepiride (Amaryl)
• glipizide (Glucotrol)
• glyburide (DiaBeta, Glynase)
• metformin (Glucophage, Glumetza, Riomet)
• pioglitazone (Actos)

Soliqua 100/33 a me ka waiʻona

Hōʻalo i ka inu nui ʻana i ka waiʻona i ka wā e lawe ana iā Soliqua 100/33. Hiki i ka waiʻona ke hoʻololi i kāu pae kō kō a hoʻonui i kou makaʻi o ka hypoglycemia (kō kō ke kō) a me ka pancreatitis (pancreas inflamed).

Inā inu ʻoe i ka ʻalekohola, e kamaʻilio me kāu kauka e pili ana i ka nui o ka palekana o ka ʻona iā ʻoe.

Hana like ʻo Soliqua 100/33

Hiki i ka Soliqua 100/33 ke launa pū me nā lāʻau ʻē aʻe. Hiki iā ia ke launa pū me kekahi mau mea hoʻopihapiha a me kekahi mau meaʻai.

Hiki i nā launa like ʻole ke kumu i nā hopena like ʻole. ʻO kahi laʻana, hiki i kekahi ke hoʻopilikia i ka maikaʻi o ka hana ʻana o ka lāʻau, ʻoiai ʻo kekahi e hoʻonui i nā hopena ʻē aʻe.

Soliqua 100/33 a me nā lāʻau ʻē aʻe

Ma lalo ka papa inoa o nā lāʻau i hiki ke launa pū me Soliqua 100/33. ʻAʻohe i loko o kēia papa inoa nā lāʻau āpau i hiki ke launa pū me Soliqua 100/33.

Ma mua o ka lawe ʻana iā Soliqua 100/33, e hoʻomaopopo pono e haʻi aku i kāu kauka a me ka kauka lāʻau e pili ana i nā kauka, over-the-counter, a me nā lāʻau ʻē aʻe āu e lawe ai. E haʻi pū iā lākou e pili ana i nā wikamina, nā mea kanu, a me nā mea hoʻopiha āu e hoʻohana ai. Hiki ke kōkua i ka hāʻawi ʻana i kēia ʻike iā ʻoe e hōʻalo i nā launa ʻole.

Inā he mau nīnau kāu e pili ana i nā launa lāʻau e hoʻopili iā ʻoe, e nīnau i kāu kauka a kauka paha.

Nā lāʻau maʻi diabetes ʻē aʻe

Lawe iā Soliqua 100/33 me nā lāʻau maʻi diabetes e hiki ke alakaʻi i nā pae kō kō haʻahaʻa haʻahaʻa a hoʻonui i kou makaʻi o ka hypoglycemia (kō kō kō. Inā lawe ʻoe i kekahi o kēia mau lāʻau, pono ʻoe e nānā pinepine i kāu kō kō kō. Eia kekahi, pono paha i kāu kauka e hoʻololi i kāu mea hana o Soliqua 100/33.

ʻO nā laʻana o nā lāʻau diabetes.

• canagliflozin (Invokana)
• dapagliflozin (Farxiga)
• empagliflozin (Jardiance)
• glyburide (DiaBeta, Glynase, Micronase)
• glimepiride (Amaryl)
• glipizide (Glucotrol)
• insulins-ʻai manawa (Humalog, Novolog)
• metformin (Glucophage)
• nateglinide (Starlix)
• repaglinide (Prandin)

Eia hou, me ka hoʻohana ʻana iā Soliqua 100/33 me nā lāʻau diabetes i kapa ʻia ʻo thiazolidinediones (TZDs) hiki ke hoʻoulu i ka wai. Hiki iā ia ke hoʻonui i kāu makaʻu o ka puʻuwai puʻuwai a i ʻole e hōʻino i nā hōʻailona o ka puʻuwai puʻuwai (e ʻike i ke kau ʻana ma lalo). Eia kekahi laʻana o kēia mau lāʻau:

• pioglitazone (Actos)
• rosiglitazone (Avandia)

Inā lawe ʻoe i kahi TZD, e kamaʻilio me kāu kauka ma mua o ka hoʻomaka ʻana iā Soliqua 100/33. Inā ʻae kāu kauka i kāu hoʻohana ʻana i kahi TZD ʻoiai e hoʻohana ana iā Soliqua 100/33, e nānā pono i nā ʻōuli o ka puʻuwai ʻole. Inā hoʻomohala ʻoe i ka puʻuwai puʻuwai, hiki i kāu kauka ke hōʻemi i ka mahele lāʻau o kāu TZD a i ʻole ke oki nei iā ʻoe.

Nā hōʻailona o ka puʻuwai puʻuwai e komo pū paha:

• pilikia hanu
• pehu i nā wāwae, nā kuʻekuʻe wāwae, a me nā wāwae
• wikiwiki a i ʻole kuʻi puʻuwai puʻuwai
• ʻeha ka umauma

ʻO nā lāʻau lapaʻau kiʻekiʻe

Lawe iā Soliqua 100/33 me kekahi mau lāʻau lapaʻau kiʻekiʻe ke hiki i ke kiʻekiʻe o ke kō a me ka hoʻonui i kou maka o ka hypoglycemia (ke kō kō. Inā lawe ʻoe i kekahi o kēia mau lāʻau, pono ʻoe e nānā pinepine i kāu kō kō kō. Eia kekahi, pono paha i kāu kauka e hoʻololi i kāu mea hana o Soliqua 100/33.

ʻO nā laʻana o nā lāʻau lapaʻau kiʻekiʻe e hiki ai ke hoʻonui i ka makaʻu o ka hypoglycemia ke lawe ʻia me Soliqua 100/33 me:

• nā mea hoʻonāukiuki angiotensin-hoʻololi i ka enzyme (ACE), e like me:
• benazepril (Lotensin)
• captopril
• enalapril (Vasotec)
• lisinopril (Zestril)
• angiotensin II receptor blockers (ARBs), e like me:
• valsartan (Diovan)
• candesartan (Atacand)
• irbesartan (Avapro)
• losartan (Cozaar)
• olmesartan (Benicar)

Hiki i nā lāʻau kahe koko ʻē aʻe ke uhi i nā ʻōuli o ke kiʻekiʻe o ke kō kō. Hoʻonui a hoʻemi paha kēia mau lāʻau i ka hopena o Soliqua 100/33 ma ka hoʻohaʻahaʻa ʻana i nā pae kō kō. Inā ʻoe e lawe i kēia mau lāʻau me Soliqua 100/33, pono paha ʻoe e nānā pinepine i kāu kō kō kō. Eia kekahi, pono paha i kāu kauka e hoʻololi i kāu mea hana o Soliqua 100/33.

ʻO nā laʻana o nā lāʻau lapaʻau kaomi koko e hiki ai ke uhi i nā hōʻailona o ke kaomi haʻahaʻa a pili paha i ka maikaʻi o ka hana a Soliqua 100/33:

• clonidine (Catapres)
• metoprolol (Lopressor, Toprol-XL)
• atenolol (Tenormin)

Nā lāʻau ʻē aʻe i hūnā i nā hōʻailona o ka hypoglycemia

Hiki i kekahi mau lāʻau ke uhi i nā hōʻailona a me nā ʻōuli o ke kiʻekiʻe o ke kō o ke kō. Inā ʻoe e lawe i kēia mau lāʻau, pono ʻoe e nānā pinepine i kāu kō kō kō. Eia kekahi, pono paha i kāu kauka e hoʻololi i kāu mea hana o Soliqua 100/33.

ʻO nā laʻana o kēia mau lāʻau:

• albuterol (ProAir, Proventil, Ventolin)
• guanethidine
• mālama ʻāina

Nā lāʻau ʻē aʻe i hiki ke hoʻohaʻahaʻa i nā pae kō kō

Lawe iā Soliqua 100/33 me kekahi mau lāʻau ʻē aʻe hiki ke alakaʻi i nā pae kō kō haʻahaʻa haʻahaʻa a hoʻonui i kou makaʻi o ka hypoglycemia (kō kō kō. Inā lawe ʻoe i kekahi o kēia mau lāʻau, pono paha ʻoe e nānā pinepine i kāu kō kō kō. Eia kekahi, pono paha i kāu kauka e hoʻololi i kāu mea hana o Soliqua 100/33.

ʻO nā laʻana o kēia mau lāʻau:

• disopyramide (Norpace)
• kekahi mau lāʻau kolesterol, e like me fenofibrate (Tricor, Triglide) a me gemfibrozil (Lopid)
• kekahi antidepressants, e like me fluoxetine (Prozac, Sarafem) a me selegiline (Emsam, Zelapar)
• octreotide (Sandostatin)
• sulfamethoxazole-trimethoprim (Bactrim, Septra)

Nā lāʻau ʻē aʻe e hoʻonui i kou kiʻekiʻe kō kō

Hiki i kekahi mau lāʻau ke hoʻonui i ke kiʻekiʻe o ke kō i kou kino. Inā ʻoe e lawe i kēia mau lāʻau, pono ʻoe e nānā i ke kiʻekiʻe o ke kō i ke kiʻekiʻe o ke koko i mea e pale aku ai i ka hyperglycemia (high sugar sugar). Eia kekahi, pono paha i kāu kauka e hoʻololi i kāu mea hana o Soliqua 100/33.

ʻO nā laʻana o kēia mau lāʻau:

• albuterol (ProAir, Proventil, Ventolin)
• kekahi mau antivirals, e like me atazanavir (Reyataz) a me lopinavir / ritonavir (Kaletra)
• kekahi mau steroid, e like me budesonide (Entocort EC, Pulmicort, Uceris), prednisone, a me fluticasone (Flonase, Flovent)
• kekahi diuretics, e like me chlorothiazide (Diuril) a me hydrochlorothiazide (Microzide)
• kekahi antipsychotics, e like me clozapine (Clozaril, Fazaclo) a me olanzapine (Zyprexa)
• kekahi mau hormoni, e like me danazol (Danazol), levothyroxine (Levoxyl, Synthroid) a me somatropin (Genotropin)
• glucagon (GlucaGen)
• niacin (Niaspan, Slo-Niacin, kekahi)
• ʻōpū oral (pills kaohi hānau)

Nā lāʻau e hoʻonui a hoʻēmi paha i nā hopena o Soliqua 100/33

Hiki i kekahi mau lāʻau lapaʻau ke hoʻololi i ka hana a Soliqua 100/33 i kou kino. Inā ʻoe e lawe i kēia mau lāʻau, pono paha ʻoe e nānā pinepine i kāu kō kō kō. Eia kekahi, pono paha i kāu kauka e hoʻololi i kāu mea hana o Soliqua 100/33.

ʻO nā laʻana o kēia mau lāʻau:

• albuterol (ProAir, Proventil, Ventolin)
• likiuma

Soliqua 100/33 a me nā mea kanu a me nā mea hoʻohui

Lawe iā Soliqua 100/33 me kekahi mau mea kanu a hoʻopili paha e hoʻonui i kou makaʻu o ka hypoglycemia (pae kō kō kō haʻahaʻa). ʻO nā laʻana o kēia mau mea:

• ʻakika alpha-lipoic
• banaba
• melon ʻawaʻawa
• chomium
• hale haʻuki
• kālika ʻiʻo prickly
• pākea keʻokeʻo

Pehea e hana ai ʻo Soliqua 100/33

Kōkua ʻo Soliqua 100/33 i ka hoʻomaikaʻi ʻana i nā pae kō kō i nā poʻe me ka maʻi diabetes type 2.

Pehea e pili ai ka insulin i ke kō kō

ʻO ka maʻamau, ke ʻai ʻoe i ka meaʻai, hoʻokuʻu i kou kino i kahi hōmona i kapa ʻia ʻo insulin. Hele ka Glucose (kō) mai ka meaʻai i kāu kahe o ke koko, a kōkua ka insulin i ka lawe ʻana iā ia i nā hunaola o kou kino. Hoʻololi nā hunaola i ka glucose i ikehu.

ʻO ka poʻe me ka maʻi diabetes type 2 ka mea maʻamau i ke kūpaʻa ʻana o ka insulin. ʻAʻole kēia i pane i ko lākou kino i ka insulin i ke ʻano e pono ai. Ma hope o ka hala ʻana o ka manawa, hiki i ka poʻe me ka maʻi diabetes type 2 ke hooki i ka hana ʻana i ka nui o ka insulin.

Ke pane ʻole kou kino i ka insulin i ke ala e pono ai, a i ʻole inā ʻaʻole lawa ka nui o ka insulin, kumu kēia i nā pilikia. ʻAʻole paha loaʻa i nā hunaola o kou kino ke glucose e pono ai e hana pololei.

Eia kekahi, loaʻa paha iā ʻoe ka nui o ka glucose i kou koko. Kapa ʻia kēia ʻo hyperglycemia (kō kō kiʻekiʻe). ʻO ka nui o ka glucose i loko o kou koko e hōʻino ai i kou kino a me nā lālā, e like me kou mau maka, puʻuwai, nā aʻa, a me nā puʻupaʻa.

He aha kā Soliqua 100/33 hana ai

Loaʻa i loko o Soliqua 100/33 nā lāʻau ʻelua. ʻO kēia ka insulin glargine, kahi insulin lōʻihi hana ʻia, a me ka lixisenatide, kahi agepona reseptor like peptide 1 (GLP-1) reseptor.

Hana ka insulin glargine i hoʻokahi ala: hoʻohaʻahaʻa ia i kāu kiʻekiʻe o ke kō i ke kahe ʻana o ka glucose mai kou kahe o ke koko i kāu mau hunaola.

Hana ʻo Lixisenatide i ʻekolu ala. ʻO ka mea mua, hoʻonui ia i ka nui o ka insulin a kou kino e hana ai. Kōkua kēia hoʻonui ʻana i ka insulin i ka neʻe ʻana o ka glucose i waho o kou kahena kōkō a i loko o kāu mau hunaola. ʻO ka lua, hana ia i kou ʻōpū e ninini hou aku ma hope o ka ʻai ʻana, e hoʻolōʻihi ana i kou manawa. A ʻo ke kolu, haʻi ʻia i kou ake e hoʻokuʻu i ka glucose liʻiliʻi i loko o kou koko.

Pehea ka lōʻihi o ka hana?

Hoʻomaka ʻo Soliqua 100/33 e hana pololei ma hope o kou hoʻopili ʻana iā ia. Eia nō naʻe, hiki i kāna hopena kiʻekiʻe loa ma kahi o 2.5 a 3 mau hola ma hope o kēlā me kēia hoʻopili.

Soliqua 100/33 a me ka hāpai keiki

Kaupalena ʻia nā ʻikepili no ka hoʻohana ʻana o Soliqua 100/33 i ka wā hāpai o nā kānaka. Eia nō naʻe, hōʻike ʻia nā noiʻi holoholona e aia paha ka weliweli o nā hānau hānau me ka hoʻohana ʻana o lixisenatide i ka wā hāpai. ʻO Lixisenatide kekahi o nā lāʻau i loaʻa ma Soliqua 100/33. No laila, hoʻohana wale ʻia ʻo Soliqua 100/33 i ka wā o ka hāpai ʻana inā ʻoi aku ka pōmaikaʻi kūpono ma mua o nā mea hiki ke loaʻa.

Inā hāpai ʻoe a hoʻolālā paha ʻoe e hāpai, e kamaʻilio me kāu kauka e pili ana i nā pilikia a me nā pono o ka hoʻohana ʻana iā Soliqua 100/33 i ka wā hāpai.

Soliqua 100/33 a me ka waiū hānai

ʻAʻole ʻike ʻia inā hele ʻo Soliqua 100/33 i ka waiū umauma. Ma mua o ka hānai ʻana, pono ʻoe e kūkākūkā me kāu kauka i nā pilikia a me nā pono o ka lawe ʻana i kēia lāʻau i ka wā e hānai ana.

Nā nīnau e pili ana iā Soliqua 100/33

Eia nā pane i kekahi o nā nīnau e nīnau pinepine ʻia e pili ana iā Soliqua 100/33.

ʻO Soliqua 100/33 ke kumu o ka loaʻa ʻana o ke kaumaha?

I nā hoʻokolohua hoʻokolohua, ʻaʻole i loaʻa ʻo Soliqua 100/33 e kumu i ka loaʻa o ke kaumaha. I ka ʻoiaʻiʻo, i hoʻokahi hoʻokolohua hoʻokolohua, ua nalowale ka poʻe i lawe iā Soliqua 100/33 no 30 mau pule ma kahi o 1.5 paona.

He mea hoihoi ia e hoʻomaopopo i kēlā me kēia lāʻau i loko o Soliqua 100/33 me he mea lā he ʻokoʻa nā hopena i ke kaupaona. ʻO kekahi o nā lāʻau lapaʻau he glargine insulin, ʻo ia kahi insulin hana lōʻihi. ʻO ka maʻamau, ua hoʻopili ʻia nā lāʻau i loko me ka insulin me ka loaʻa kaumaha.

Eia nō naʻe, kapa ʻia ka lāʻau ʻē aʻe ma Soliqua 100/33 i lixisenatide, kahi like me ka glucagon-like peptide 1 (GLP-1) agonist reseptor. Ua hōʻike ʻia nā lāʻau i ka papa lāʻau lapaʻau GLP-1 i ke kaupaona ʻana ma ke ʻano he hopena i nā ʻano noiʻi maʻi.

Inā ʻoe hopohopo e pili ana i nā hopena a Soliqua 100/33 i loaʻa i kou kaupaona, e kamaʻilio me kāu kauka.

ʻO Soliqua 100/33 insulin?

ʻAe, ʻo Soliqua 100/33 i loaʻa ka insulin. Hana ʻia ʻo Soliqua 100/33 i ʻelua mau lāʻau, a ʻo kekahi o ia mau insulin glargine, kahi insulin hana lōʻihi.

ʻO ka lāʻau ʻelua ka lixisenatide, kahi like me ka glucagon-like peptide 1 (GLP-1) agonist reseptor.

ʻO Soliqua 100/33 hana lōʻihi?

Ae. Loaʻa i loko o Soliqua 100/33 nā lāʻau lapaʻau ʻeleu ʻelua. ʻO kekahi o kēia ka insulin glargine, kahi insulin lōʻihi lōʻihi.

Hiki iā Soliqua 100/33 ke hoʻohana e mālama i ka maʻi diabetes type 1?

ʻAʻole, ʻaʻole pono e hoʻohana ʻia ʻo Soliqua 100/33 e mālama ai i ka maʻi diabetes type 1. ʻAʻole aʻo ʻia ʻo Soliqua 100/33 a ʻae ʻia e ka Food and Drug Administration e mālama i kēlā ʻano. ʻAe ʻia wale nō e mālama i ka maʻi diabetes type 2.

Nā ʻōlelo aʻoaʻo a Soliqua 100/33

Ma mua o ka lawe ʻana iā Soliqua 100/33, e kamaʻilio me kāu kauka e pili ana i kāu mōʻaukala olakino. ʻAʻole kūpono paha ʻo Soliqua 100/33 iā ʻoe inā he ʻano olakino kāu. Pākuʻi ʻia kēia mau mea:

• ʻO ka maʻi kīwī. Inā loaʻa ʻoe i ka maʻi puʻupaʻa, ʻo ka lawe ʻana iā Soliqua 100/33 e hōʻino paha i kou ʻano. Inā kaumaha kou ʻano, pono paha ʻoe e haʻalele i ka lawe ʻana iā Soliqua 100/33. Mai lawe i kēia lāʻau inā loaʻa ʻoe i ka maʻi puʻuwai koʻikoʻi.
• Holo ka ʻōpū lohi. ʻO Lixisenatide, kekahi o nā lāʻau i Soliqua 100/33, hoʻolohi i ka hana o kou ʻōpū ʻōpū. Inā loaʻa iā ʻoe ka gastroparesis, ʻo ia hoʻi ka ʻeli ʻana o kou kino i ka meaʻai me ka lohi, ʻo ka lawe ʻana iā Soliqua 100/33 e hōʻino paha i kou ʻano. ʻAʻole pono ka poʻe me gastroparesis koʻikoʻi e lawe i kēia lāʻau.
• ʻO nā pilikia Pancreas a i ʻole ka gallbladder, a i ʻole nā ​​maʻi hoʻohana ʻona. Hiki i ka Soliqua 100/33 ke hoʻonui i kou makaʻi o ka pancreatitis. Hiki paha iā ʻoe ke makaʻu nui i ka pancreatitis inā loaʻa iā ʻoe kahi mōʻaukala o pancreatitis, nā pōhaku gallbladder, a i ʻole ka waiʻona. Inā loaʻa iā ʻoe kahi mōʻaukala o kēia mau pilikia, e kamaʻilio me kāu kauka e pili ana inā ʻo Soliqua 100/33 ka mea kūpono iā ʻoe.

Soliqua 100/33 overdose

ʻO ka lawe ʻana i ka nui o kēia lāʻau i hiki ke hoʻonui i kou makaʻi i nā hopena ʻino.

Nā hōʻailona overdose

Hiki i nā ʻōuli o ka overdose ke komo pū me:

• hypoglycemia koʻikoʻi (kō kō kō ke kō.), kahi e hiki ai ke hoʻoluliluli, hopohopo, a huikau hoʻi
• hypokalemia (pae potassium haʻahaʻa), hiki ke kumu i ka nāwaliwali, ka paʻa paʻa ʻana, a me nā kūpikipiki o nā mākala
• nā pilikia o ka gastrointestinal, hiki i ke kīpē, kahe, a me ka luaʻi

He aha e hana ai inā he overdose

Inā manaʻo ʻoe ua lawe nui ʻoe i kēia lāʻau, e kāhea i kāu kauka a i ʻole e ʻimi i ke alakaʻi mai ka ʻAmelika Hui Pū ʻIa Poison Control ma 800-222-1222 a i ʻole ma o kā lākou mea pono pūnaewele. Akā inā koʻikoʻi kāu mau ʻōuli, e kāhea iā 911 a i ʻole e hele koke i kahi lumi pilikia kokoke.

Soliqua 100/33 pau a me kahi waiho

Ke haʻalele ʻia ʻo Soliqua 100/33 mai ka hale kūʻai lāʻau, e hoʻohui ka kauka i kahi lā palena pau i ka lepili ma ka ipu. ʻO kēia lā maʻamau hoʻokahi makahiki mai ka lā i hāʻawi ʻia ai ka lāʻau.

ʻO ke kumu o kēlā mau lā palena pau e hōʻoia i ka hopena o nā lāʻau i kēia manawa. ʻO ke kūlana o ka Food and Drug Administration (FDA) i kēia manawa e hōʻalo i ka hoʻohana ʻana i nā lāʻau i make.

Pehea ka lōʻihi o ka maikaʻi o ka lāʻau e hiki ai ke hilinaʻi i nā kumu he nui, me ke ʻano a me kahi e mālama ʻia ai ka lāʻau. E mālama i kāu peni Soliqua 100/33 i loko o kāu pahu hau, ma kahi mahana ma waena o 36 ° F a me 46 ° F (2 ° C a me 8 ° C). Mai hoʻokuʻu i kāu mau peni.

Ma hope o ka hoʻohana mua ʻana o kēlā me kēia peni, hiki iā ʻoe ke mālama iā ia i ka mahana wela (77 ° F / 25 ° C), akā e pale pono iā ia mai ka mālamalama. E hoʻolei i kēlā me kēia peni ma hope o 28 mau lā mai kona hoʻohana mua ʻana.

Inā loaʻa iā ʻoe kahi lāʻau i hoʻohana ʻole ʻia i hala i ka lā palena pau, e kamaʻilio me kāu kauka lāʻau e pili ana inā hiki paha iā ʻoe ke hoʻohana.

ʻO ka ʻike ʻoihana no Soliqua 100/33

Hāʻawi ʻia ka ʻike aʻe no nā kauka lapaʻau a me nā ʻoihana ola.

Nā Hōʻike

Ua ʻae ʻia ʻo Soliqua 100/33 no ka hoʻohana ʻana me ka papaʻai a me ka hoʻoikaika kino ʻana e hoʻomaikaʻi ai i ke kaohi glycemic i nā mākua me ka type 2 diabetes mellitus.

Mekanism o ka hana

ʻO Soliqua 100/33 kahi hui o ka insulin glargine (kahi basal insulin analog) a me ka lixisenatide (kahi like peptide 1 [GLP-1] agonist reseptor).

Hoʻohaʻahaʻa ka insulin glargine i ke kō glucose ma o ka hoʻonui ʻana i ka lawe ʻana o ka glucose peripheral a hoʻemi i ka hana glucose mai ke ake. Hoʻoemi ʻo Lixisenatide i ke kō glucose ma o ka hoʻonui ʻana i ka huna insulin, hoʻoliʻiliʻi i ka huna ʻana o ka glucagon, a me ka hoʻolōʻihi ʻana i ka ʻōpū o ka ʻōpū.

Pharmacokinetics a me ka metabolism

ʻAʻohe hopena o ka lākiō glargine-i-lixisenatide lākiō i nā pharmacokinetics o nā ʻāpana ʻelua.

ʻAʻohe piko ʻo Insulin glargine a hana metabolism hapa ʻia i ka terminus carboxyl o ke kaulahao B i ka depot subcutaneous.

ʻO ka manawa e hoʻonui ai i ka max no ka lixisenatide he 2.5 a 3 mau hola. He 55 pakeneka paʻa paʻa o Lixisenatide a hoʻopau ʻia e ka mimi a me ka proteolytic degradation. ʻO ka hapalua o ke ola ma kahi o 3 mau hola.

Nā Kūʻai Kūʻai

Hoʻopiʻi ʻia ʻo Soliqua 100/33 i nā mea maʻi:

• i ka wā o ka hypoglycemic episodes
• me kahi moʻaukala o ka hypersensitivity nui i ka insulin glargine a i ʻole lixisenatide

Waihona

Pono e mālama ʻia nā peni ʻo Soliqua 100/33 i loko o ka pahu hau, ma kahi mahana ma waena o 36 ° F a me 46 ° F (2 ° C a me 8 ° C), akā ʻaʻole paʻa. Ma hope o ka hoʻohana mua, hiki ke mālama i nā peni i ka mahana wela o 77 ° F (25 ° C). E pale ʻia lākou mai ka mālamalama. E hoʻolei i ka peni ma hope o 28 mau lā mai ka hoʻohana mua.

Hoʻolaha: Ua hana ʻo MedicalNewsToday i nā hana āpau e hōʻoia i ka pololei, ka laulā, a me ka lā hou o nā ʻike āpau. Eia nō naʻe, ʻaʻole pono e hoʻohana i kēia ʻatikala i pani no ka ʻike a me ka mākaukau o kahi loea mālama ola laikini. E nīnau mau ʻoe i kāu kauka a i ʻole ʻoihana olakino ʻē aʻe ma mua o ka lawe ʻana i nā lāʻau. Hiki ke loli i ka ʻike o ka lāʻau i loko a ʻaʻole i manaʻo ʻia e uhi i nā hoʻohana a pau, nā kuhikuhi, ka mālama ʻana, nā ʻōlelo aʻoaʻo, nā launa lāʻau, nā hopena maʻi ʻaʻai, a me nā hopena maikaʻi ʻole. ʻO ka loaʻa ʻole o nā ʻōlelo aʻoaʻo a i ʻole nā ​​ʻike ʻē aʻe no kahi lāʻau i hāʻawi ʻia ʻaʻole ia e hōʻike i ka palekana o ka lāʻau a lāʻau paha i kūpono no nā mea maʻi āpau a i ʻole nā ​​hoʻohana kikoʻī āpau.