Ribavirin: ka lāʻau no ka hepatitis C
Anter
He lāʻau ʻo Ribavirin, ke pili ʻia me nā lāʻau lapaʻau ʻē aʻe, e like me ka alpha interferon, i hōʻike ʻia no ka mālama ʻana i ka maʻi hepitis C.
E hoʻohana wale ʻia kēia lāʻau inā koi ʻia e ke kauka a hiki ke kūʻai ʻia ma ke hōʻike ʻana i kahi kuhikuhi.
No ke aha ia
Hōʻike ʻia ʻo Ribavirin no ka mālama ʻana i ka hepatitis C mau loa i nā mākua a me nā keiki ma mua o 3 mau makahiki, i ka hui pū ʻia me nā lāʻau ʻē aʻe no ka maʻi, a ʻaʻole pono e hoʻohana wale ʻia.
E aʻo pehea e ʻike ai i nā ʻōuli o ka maʻi hepa C.
Pehea e lawe ai
Hoʻololi ka lāʻau i koi ʻia e like me ka makahiki, ke kaupaona o ke kanaka a me nā lāʻau i hoʻohana pū ʻia me ka ribavirin. No laila, e alakaʻi mau ʻia ka mahele lāʻau e ka hepatologist.
Ke loaʻa ʻole kahi ʻōlelo kikoʻī, hōʻike nā alakaʻi ākea:
- Nā mākua ma lalo o 75 kg: ka hopena o 1000 mg i kēlā me kēia lā (5 capsule o 200 mg) i kēlā me kēia lā, ʻoki ʻia i 2 mau kaha;
- Nā mākua ma luna o 75 kg: kahi mahele lāʻau o 1200 mg (6 capsule o 200 mg) i kēlā me kēia lā, i māhele ʻia i 2 mau lā.
I ka hihia o nā keiki, e helu mau ʻia ka mahele lāʻau e ka pediatrician, a ʻo ka paipai awelika i koi ʻia i kēlā me kēia lā he 10 mg / kg ke kaupaona.
Nā hopena ʻē aʻe
ʻO kekahi o nā hopena ʻē aʻe i hiki ke hana ʻia i ka wā o ka mālama ʻana me ka ribavirin he anemia, anorexia, kaumaha, insomnia, ʻeha poʻo, ʻūpē, hoʻoliʻiliʻi hoʻoliʻiliʻi, paʻakikī hanu, ʻūhā, diarrhea, nausea, ʻeha o ka ʻōpū, nalo ka lauoho, dermatitis, ʻili, maloʻo ʻili, nāʻiʻo a me nā ʻeha pū, ka wela, ka haʻalulu, ka ʻeha, ka luhi, nā hopena ma ka pūnaewele injection a me ka huhū.
ʻO wai ka mea pono ʻole e lawe
Hoʻopiʻi ʻia ʻo Ribavirin i ka poʻe me ka hypersensitivity i ka ribavirin a i ʻole i kekahi o nā mea e loaʻa ana, ʻoiai ka hānai ʻana i ka waiū, i ka poʻe me ka mōʻaukala mua o nā maʻi puʻuwai nui, e like me ka maʻi puʻuwai kū ʻole a i ʻole kaohi ʻole ʻia, i nā mahina ʻeono i hala. cirrhosis a me hemoglobinopathies.
Hoʻonohonoho ʻia ka hoʻomaka ʻana o ka interferon therapy i nā mea maʻi i hui pū ʻia me ka maʻi hepitis C a me ka maʻi HIV, me ka cirrhosis a me ka helu Child-Pugh ≥ 6.
Eia hou, ʻaʻole pono e hoʻohana ʻia ka lāʻau lapaʻau e nā wahine hāpai a pono e hoʻomaka wale ʻia ma hope o ka loaʻa ʻana o kahi hopena maikaʻi ʻole ma kahi hōʻike hāpai hāpai i lawe koke ʻia ma mua o ka hoʻomaka ʻana o ka lāʻau.