Ka maʻi ʻaʻai Peritoneal: He aha kāu e ʻike ai

Anter

• ʻO ka maʻi ʻaʻai me ke kanesa peritoneal lua
• Kumumua
• ʻĀlua
• Nā ʻōuli o ka maʻi ʻaʻai peritoneal
• Nā pae o ka maʻi ʻaʻai peritoneal
• Maʻi ʻaʻai peritoneal mua
• Maʻi ʻaʻai peritoneal lua
• Nā kumu maʻi ʻaʻai Peritoneal a me nā kumu pilikia
• Pehea e ʻike ʻia ai ka maʻi ʻaʻai peritoneal
• Pehea e haʻi ai i ka ʻokoʻa ma waena o ka maʻi ʻaʻai peritoneal a me ka maʻi ʻaʻai ovarian i ka hōʻoia ʻana
• Mālama i ka maʻi ʻaʻai peritoneal
• ʻOki kino
• ʻO Chemotherapy
• Pahuhopu kau ʻia
• He aha ke kuanaʻike?
• Nā helu ola
• Maʻi ʻaʻai peritoneal mua
• Maʻi ʻaʻai peritoneal lua
• E ʻimi i ke kākoʻo

ʻO ka maʻi ʻaʻai Peritoneal kahi maʻi ʻaʻai laha ʻole e hana ʻia i ka papa lahilahi o nā hunaola epithelial e hoʻopili ana i ka paia o loko o ka ʻōpū. Kapa ʻia kēia ʻili ka peritoneum.

Pale ka peritoneum a uhi i nā ʻokena i loko o kou ʻōpū, me nā:

• ʻōpū
• ʻōpū
• ʻūhā
• kōpū

Hoʻopuka pū ka peritoneum i kahi wai lubricating e hiki ai i nā ʻōpū ke neʻe maʻalahi i loko o ka ʻōpū.

Ma muli o ka hele pinepine ʻole ʻana o kāna mau hōʻailona, ​​ʻike pinepine ʻia ka maʻi ʻaʻai peritoneal ma kahi pae hope.

ʻOkoʻa kēlā me kēia hihia o ka maʻi ʻaʻai peritoneal. Hoʻololi kēlā a me kēia i ka nānā ʻana. Ua hoʻomaikaʻi ʻia nā mālama hou i nā makahiki he 20 i hala aku nei.

ʻO ka maʻi ʻaʻai me ke kanesa peritoneal lua

ʻO nā inoa o ke kumu a me ke kula kiʻekiʻe e pili ana i kahi i hoʻomaka ai ka maʻi ʻaʻai. ʻAʻole ana nā inoa i ke ana o ka maʻi ʻaʻai.

Kumumua

Hoʻomaka a hoʻomohala ka maʻi ʻaʻai peritoneal mua i ka peritoneum. Hoʻololi wale ia i nā wahine a ʻaʻole pili iki i nā kāne.

Pili ka maʻi ʻaʻai peritoneal mua i ka maʻi ʻaʻai ovarian epithelial. Hana ʻia nā mea ʻelua i ka ala like a loaʻa kahi ʻano like.

ʻO kahi ʻano laha ʻole o ka maʻi ʻaʻai peritoneal mua he mesothelioma maligno peritoneal.

ʻĀlua

Hoʻomaka ka hoʻomaka ʻana o ka maʻi ʻaʻai peritoneal lua i loko o kahi ʻōpū ʻē aʻe a laila pālahalaha (metastasize) i ka peritoneum.

Hiki ke hoʻomaka i ka maʻi ʻaʻai peritoneal lua i ka:

• ovaries
• paipu fallopian
• ʻōpū
• ʻōpū
• ʻōpū liʻiliʻi
• kolonā
• ʻūhā
• pakui

Hiki i ka maʻi ʻaʻai peritoneal lua ke hoʻololi i nā kāne a me nā wahine. ʻOi aku ka maʻamau ma mua o ka maʻi ʻaʻai peritoneal mua.

Kuhi nā kauka ma waena o 15 a me 20 pākēneka o ka poʻe me ka maʻi ʻaʻai kala e hoʻomohala i nā metastases i ka peritoneum. Ma kahi o 10 a 15 pākēneka o ka poʻe me ka maʻi ʻaʻai ʻōpū e hoʻomohala i nā metastases ma ka peritoneum.

Ke metastasize ka maʻi ʻaʻai mai kāna pūnaewele kumu, e loaʻa i ka pūnaewele hou ke ʻano like o nā hunaola maʻi ʻaʻai e like me ka pūnaewele mua.

Nā ʻōuli o ka maʻi ʻaʻai peritoneal

ʻO nā ʻōuli o ka maʻi ʻaʻai peritoneal kaukaʻi ʻia i ka ʻano a me ke kahua o ka maʻi ʻaʻai. I kona wā mua, ʻaʻohe paha ʻōuli. I kekahi manawa ke holomua ka maʻi ʻaʻai peritoneal ʻaʻohe paha ʻōuli.

Hiki ke maopopo ʻole i nā ʻōuli mua a hoʻomaka ʻia paha e nā ʻano kumu ʻē aʻe. Hiki i nā ʻōuli o ke kanesa peritoneal ke hoʻopili pū me:

• ʻōpū o ka ʻōpū a i ʻole ʻeha
• hoʻonui ʻōpū
• kahi manaʻo o ke kaomi i loko o ka ʻōpū a i ʻole ke pelvis
• piha ma mua o kou hoʻopau ʻana i ka ʻai
• hoʻomālō
• nausea a luaʻi paha
• ʻōpū a me nā hoʻololi urinary
• nalo ʻai ʻole
• ka pohō a me ka loaʻa kaumaha
• hoʻokuʻu hoʻokuʻu
• ʻeha kua
• luhi

Ke holo nei ka maʻi ʻaʻai, hiki i kahi wai wai ke hōʻiliʻili i loko o ka lua o ka ʻōpū (ascites), hiki ke kumu:

• nausea a luaʻi paha
• pokole o ka hanu
• ʻeha ka ʻōpū
• luhi

Hiki i nā ʻōuli o ke kuni peritoneal hope loa ke komo pū:

• hoʻopau piha i ka ʻōpū a me ka urinary
• ʻeha ka ʻōpū
• hiki ʻole ke ʻai a inu paha
• ka luaʻi

Nā pae o ka maʻi ʻaʻai peritoneal

Ke hōʻike mua ʻia, hoʻokumu ʻia ka maʻi ʻaʻai peritoneal e like me ka nui, kūlana, a me kahi e hoʻolaha ʻia ai. Hāʻawi ʻia hoʻi i kahi papa, e kuhi nei pehea ka wikiwiki o ka hiki ke pālahalaha.

Maʻi ʻaʻai peritoneal mua

Hoʻokomo ʻia ka maʻi ʻaʻai peritoneal mua me ka ʻōnaehana like i hoʻohana ʻia no ka maʻi ʻaʻai ovarian mai ka like o nā maʻi ʻaʻai. Akā papa pinepine ʻia ka maʻi ʻaʻai peritoneal ma ke ʻano he pae 3 a i ʻole pae 4. ʻElua mau mua o ka maʻi ʻaʻai Ovarian.

Kahua 3 ua mahele ʻia i ʻekolu mau anuu hou aʻe:

• 3A. Ua pālahalaha ʻia ka maʻi ʻaʻai i nā pūnana lymph ma waho o ka peritoneum, a i ʻole ua hoʻolaha ʻia nā hunaola maʻi maʻi i ka papa o ka peritoneum, ma waho o ka pelvis.
• 3B. Ua pālahalaha ka maʻi ʻaʻai i ka peritoneum ma waho o ka pelvis. ʻO ka maʻi ʻaʻai ma ka peritoneum he 2 kenimika (cm) a ʻoi aku ka liʻiliʻi. Ua pālahalaha paha i nā lymph nodes ma waho o ka peritoneum.
• 3C. Ua pālahalaha ka maʻi ʻaʻai i ka peritoneum ma waho o ka pelvis a. ʻO ka maʻi ʻaʻai ma ka peritoneum ʻoi aku ka nui ma mua o 2 cm. Ua pālahalaha paha i nā lymph nodes ma waho o ka peritoneum a i ʻole i ka ʻili o ke akepaʻa a i ʻole ke kīkala.

I loko o pae 4, ua pālahalaha ka maʻi ʻaʻai i nā kino ʻē aʻe. Mahele hou ʻia kēia anuu:

• 4A. Loaʻa nā hunaola maʻi ʻaʻai i loko o ka wai e kūkulu a puni nā māmā.
• 4B. Ua pālahalaha ʻia ka maʻi ʻaʻai i nā ʻokena a me nā mea ma waho o ka ʻōpū, e like me ke ake, nā akemāmā, a i ʻole nā ​​aʻa lymph.

Maʻi ʻaʻai peritoneal lua

Hoʻonohonoho ʻia ka maʻi ʻaʻai peritoneal lua e like me ka pūnaewele maʻi ʻaʻai mua. Ke pālahalaha ʻia kahi maʻi ʻaʻai mua i kekahi ʻāpana o ke kino, e like me ka peritoneum, maʻa maʻamau ia ma ke ʻano he pae 4 o ka maʻi ʻaʻai kumu.

Ua hōʻike ʻia ma kahi o 15 pākēneka o ka poʻe me ka maʻi ʻaʻai kala a kokoke 40 pākēneka o ka poʻe me ka pae 2 a 3 mau ʻōpū ʻōpū i komo i loko peritoneal.

Nā kumu maʻi ʻaʻai Peritoneal a me nā kumu pilikia

ʻAʻole ʻike ʻia ke kumu o ka maʻi ʻaʻai peritoneal.

No ka maʻi ʻaʻai peritoneal mua, loaʻa nā kumu pilikia i:

• Makahiki. Ke hele a makua ʻoe, e hoʻonui ana i kou makaʻi.
• Nā Genetics. ʻO ka moʻolelo ʻohana o ka maʻi ʻaʻai ovarian a i ʻole peritoneal e hoʻonui ai i kou makaʻi. Lawe i ka BRCA1 a i ʻole BRCA2 gene mutation a i ʻole kekahi o nā ʻiʻo no Lynch syndrome e hoʻonui pū ai i kou makaʻu.
• Hoʻoikaika Hormone. ʻO ka lawe ʻana i ka hormone therapy ma hope o ka menopause e hoʻonui iki ai i kou makaʻi.
• Kaona a me ke kiʻekiʻe. ʻO ka momona a obesity paha ka mea e hoʻonui ai i kou makaʻi. Hoʻonui ka pilikia i ka poʻe kiʻekiʻe.
• Endometriosis. Hoʻonui ka endometriosis i kou makaʻi.

Nā kumu pili i ua hoʻēmi pilikia o ka peritoneal a i ʻole ovarian maʻi ʻaʻai pū me:

• ka lawe ʻana i nā lāʻau hoʻomake hānau
• hānau keiki
• hānai umauma
• hoʻoheheʻe tubal, hoʻohemo Tube tuber, a hoʻohemo ovary paha

Hoʻomaopopo e hoʻoliʻiliʻi ka hoʻoneʻe ovary i ka makaʻu o ka maʻi ʻaʻai peritoneal akā ʻaʻole ia e hoʻoneʻe loa iā ia.

Pehea e ʻike ʻia ai ka maʻi ʻaʻai peritoneal

ʻIke ka hōʻike ʻana o ka maʻi ʻaʻai peritoneal ʻelua a me ka lua o ka maʻi paʻakikī i nā wā mua. ʻO kēia no ka maopopo ʻole o nā ʻōuli a hiki ke hāʻawi maʻalahi ʻia i nā kumu ʻē aʻe.

Loaʻa pinepine ka maʻi ʻaʻai peritoneal i ka wā o ke kaha e hoʻoneʻe i kahi tumo i ʻike ʻia ma kahi ʻē aʻe i loko o ka ʻōpū.

E nānā kino kāu kauka iā ʻoe, e lawe i kahi mōʻaukala olakino, a nīnau iā ʻoe e pili ana i kāu mau ʻōuli. Kauoha paha lākou i kahi moʻo o nā hoʻokolohua e hoʻoholo ai i kahi kuhi.

Hoʻohana ʻia nā hoʻokolohua e kuhikuhi ai i ka maʻi ʻaʻai peritoneal:

• Nā hoʻāʻo kiʻi o ka ʻōpū a me ka pelvis. Hōʻike paha kēia i ka ascites a i ʻole nā ​​ulu. Hoʻopili nā hōʻike i ka scan CT, ultrasound, a me MRI. Eia nō naʻe, ke hoʻohana nei ka maʻi ʻaʻai peritoneal i ka CT a me ka MRI scans.
• ʻO Biopsy o kahi e nānā pono ʻole i kahi scan, me ka hemo ʻana o ka wai mai ascites, e nānā no nā pūnaʻi maʻi maʻi. E kūkākūkā i nā maikaʻi a me nā maikaʻi ʻole o kēia me kāu kauka. Hoʻopilikia pū ke kaʻina hana i ka lulu ʻana i ka paia o ka ʻōpū me nā hunaola maʻi ʻino.
• Nā hoʻāʻo koko e nānā i nā kemika e hoʻokiʻekiʻe ʻia i ka maʻi ʻaʻai peritoneal, e like me CA 125, kahi kemika i hana ʻia e nā hunaola tumo. ʻO HE4 kahi hōʻailona koko hou. ʻOi aku ka liʻiliʻi ma mua o CA 125 e hoʻokiʻekiʻe ʻia e nā kūlana noncancerous.
• Laparoscopy a i ʻole laparotomy. ʻO kēia nā hana hoʻouka minimally invasive e nānā pono i ka peritoneum. Manaʻo lākou he "kūlana gula" i ka hōʻailona.

Ke hoʻomau nei ka noiʻi ʻana i nā ʻano ʻoi aku ka maikaʻi a me ka mua o ka ʻike no ka maʻi ʻaʻai peritoneal.

A manaʻo ʻia e hoʻomohala ʻia kahi “biopsy wai.” Kuhi kēia i kahi hoʻokolohua koko e hiki ke nānā i kahi hui o nā biomarkers tumo. ʻO kēia ka mea e hiki ai i ka mālama mua ʻana no kekahi poʻe.

Pehea e haʻi ai i ka ʻokoʻa ma waena o ka maʻi ʻaʻai peritoneal a me ka maʻi ʻaʻai ovarian i ka hōʻoia ʻana

ʻAno like ka maʻi ʻaʻai Peritoneal me ka maʻi ʻaʻai ovarian epithelial holomua. Pili nā mea ʻelua i ke ʻano o nā hunaola. Ua hoʻomohala ʻia nā ana hoʻohālikelike e hoʻokaʻawale iā lākou e ka.

Manaʻo ʻia he maʻi ʻaʻai peritoneal mua inā ka:

• ʻike ʻia nā ovaries maʻamau
• ʻaʻole nā ​​hunaola maʻi i ka papa ovary
• ʻO ka tumous ka mea nui loa (e hana ana i kahi wai)

ua hōʻike ʻo ka makahiki awelika o ka poʻe me ka maʻi ʻaʻai peritoneal mua ma mua o ka poʻe me ka maʻi ʻaʻai ovarian epithelial.

Mālama i ka maʻi ʻaʻai peritoneal

Loaʻa paha iā ʻoe kahi kime lapaʻau e like me:

• he kauka
• he ʻākōlika
• he radiologist
• he pathologist
• he gastroenterologist
• he loea ʻeha
• nā kahu maʻi loea
• hoʻomalu mālama palliative

ʻO ka mālama ʻana no ka maʻi ʻaʻai peritoneal mua he like ia me ka maʻi ʻaʻai ovarian. No ka maʻi ʻaʻai peritoneal ʻelua a me nā haumāna ʻelua, pili ka mālama ʻana i kēlā me kēia kanaka i ka wahi a me ka nui o ka tumo a me kou olakino maʻamau.

ʻO ka mālama ʻana no ka maʻi ʻaʻai peritoneal lua e pili ana hoʻi i ke kūlana o ka maʻi ʻaʻai mua a me kāu pane i ka mālama ʻana iā ia.

ʻOki kino

ʻO ke kaha keʻoki ka mua. E lawe kahi kauka lapaʻau i ka nui o ka maʻi ʻaʻai e hiki ai. Hiki iā lākou ke hemo:

• kou kōpū (hysterectomy)
• kou ovaries a me nā fallopian paipu (oophorectomy)
• ka papa o nā momona momona kokoke i nā ovaries (omentum)

E hoʻoneʻe aku nō kāu mea kauka lapaʻau i nā mea like ʻole i ka ʻōpū no ka hoʻāʻo hou.

ʻO ka holomua i ka kikoʻī o nā ʻenehana ʻoki lāʻau, i ʻike ʻia ʻo ke ʻoki ʻana o cytoreductive (CRS), i hiki ai i nā kaukipō ke wehe i nā mea maʻi ʻoi loa. Ua hoʻomaikaʻi kēia i ka nānā o ka poʻe me ka maʻi ʻaʻai peritoneal.

ʻO Chemotherapy

Hiki i kāu kauka ke hoʻohana i ka chemotherapy ma mua o ke kahakaha ʻana e hoʻoliʻiliʻi i ka tumo i ka hoʻomākaukau no ke ʻoki. Hiki iā lākou ke hoʻohana ia mea ma hope o ke kaha ʻana e luku i nā keena maʻi maʻi maʻi i koe.

ʻO kahi hana hou o ka hāʻawi ʻana i ka chemotherapy ma hope o ke kahakaha ʻana ua hoʻonui i kona pono i nā manawa he nui.

Hoʻohana ka ʻenehana i ka wela i hui pū ʻia me ka chemotherapy i hāʻawi pololei ʻia i ka pūnaewele maʻi ʻaʻai peritoneal. ʻIke ʻia ʻo hyperthermic intraperitoneal chemotherapy (HIPEC). He lāʻau lapaʻau hoʻokahi kēia i hāʻawi pololei ʻia ma hope o ke kaha ʻana.

ʻO ka hui pū ʻana o CRS a me HIPEC ua "hoʻololi" i ka mālama ʻana i ka maʻi ʻaʻai peritoneal, e like me ka nui o nā kānaka noiʻi. Akā ʻaʻole ia e ʻae piha ʻia e like me ka maʻamau maʻamau. ʻO kēia no ka mea ʻaʻohe hoʻokolohua hoʻomanawanui a me nā pūʻulu kaohi.

Ke hoʻomau nei ka noiʻi. ʻAʻole koi ʻia ʻo HIPEC ke loaʻa nā metastases ma waho o ka ʻōpū a i kekahi mau hanana ʻē aʻe.

Loaʻa nā hopena ʻaoʻao āpau i ka chemotherapy. Kūkākūkā he aha kēia mau mea a pehea e lawelawe ai iā lākou me kāu hui lapaʻau.

Pahuhopu kau ʻia

I kekahi mau hihia, hiki ke hoʻohana ʻia kahi lāʻau hoʻomohala hoʻomōhala. Kūpono kēia mau lāʻau i ka hoʻōki ʻana i nā hunaola maʻi ʻaʻai me ka ʻole o ka hōʻeha ʻana i nā hunaola maʻamau. Hoʻopili ʻia nā therapies i kuhi ʻia i kēia mau mea:

• Nā monemona monoclonal nā mea pahuhopu i nā hunaola e hāpai i ka ulu ʻana o ka maʻi ʻaʻai. Hoʻohui ʻia paha kēia mau mea me kahi lāʻau chemotherapy.
• Nā mea hoʻopale PARP (poly-ADP ribose polymerase) ālai i ka hoʻoponopono ʻana iā DNA.
• Nā mea kāohi Angiogenesis pale i ka ulu o ke kīʻaha koko i nā tumors.

Hoʻohana pū ʻia ʻo ka Hormonal therapy, radiation radiation, a me ka immunotherapy i kekahi mau hihia o ka maʻi ʻaʻai peritoneal mua.

He aha ke kuanaʻike?

ʻO ka nānā ʻana no ka poʻe me ka maʻi ʻaʻai peritoneal mua a i ʻole ʻelua hoʻi ua hoʻomaikaʻi maikaʻi loa ʻia i loko o nā makahiki he hala i hala aku nei no ka holomua o ka mālama ʻana, akā ʻilihune nō naʻe. ʻO ka hapa nui kēia no ka mea ʻaʻole ʻike pinepine ʻia ka maʻi ʻaʻai peritoneal a hiki i kahi pae holomua. Eia kekahi, hoʻi paha ka maʻi ʻaʻai ma hope o ka mālama ʻana.

He paʻakikī nā ʻōuli e kuhikuhi, akā inā loaʻa iā ʻoe kekahi o nā ʻōuli laulā e hoʻomau nei, e nānā me kāu kauka. ʻO ke kuhi ma mua e alakaʻi i kahi hopena maikaʻi aʻe.

Nā helu ola

Maʻi ʻaʻai peritoneal mua

E like me ka 2019, ʻo ka helu ola ʻelima mau makahiki no nā wahine me nā ʻano ovarian like ʻole, ka paipu fallopian, a me nā maʻi ʻaʻai peritoneal he 47 pakeneka. ʻOi aku ka kiʻekiʻe o kēia helu no nā wahine ma lalo o 65 (60 pākēneka) a haʻahaʻa no nā wahine ma mua o 65 (29 pākēneka).

ʻO nā helu helu e ola ai no ka maʻi ʻaʻai peritoneal mua mai nā haʻawina liʻiliʻi loa.

ʻO kahi laʻana, ʻo 29 mau wahine me ka maʻi ʻaʻai peritoneal mua i hōʻike i ka manawa ola he 48 mau mahina ma hope o ka lapaʻau ʻana.

ʻOi aku ka maikaʻi o kēia ma mua o ka pae ola ʻelima mau makahiki i hōʻike ʻia ma kahi noiʻi 1990 i kau ʻia ma waena.

Maʻi ʻaʻai peritoneal lua

ʻO ka helu ola no ka maʻi ʻaʻai peritoneal lua hoʻi e kaukaʻi ʻia i ka pae o ka pūnaewele maʻi ʻaʻai mua a me ke ʻano o ka mālama ʻana. Hōʻike kahi helu liʻiliʻi o nā noiʻi e hoʻomaikaʻi ana kahi hui like ʻana o CRS a me HIPEC i nā helu ola.

ʻO kahi laʻana, kahi noiʻi i hōʻike ʻia ma 2013 i nānā i ka poʻe 84 me ka maʻi ʻaʻai kala i pāhola ʻia i ka peritoneum. Hoʻohālikelike ia i ka poʻe i loaʻa ka chemotherapy ʻōnaehana i ka poʻe i loaʻa iā CRS a me HIPEC.

ʻO ke ola no ka hui chemotherapy he 23.9 mau mahina ke hoʻohālikelike ʻia me 62.7 mau mahina no ka hui i mālama ʻia me CRS a me HIPEC.

E ʻimi i ke kākoʻo

E makemake paha ʻoe e kamaʻilio me nā poʻe ʻē aʻe e hele ana i ka lāʻau a i ʻole me nā lālā o ko lākou ʻohana.

Loaʻa ka laina kākoʻo ʻAmelika ʻAmelika i 24/7 i ka lā ma 800-227-2345. Hiki iā lākou ke kōkua iā ʻoe e ʻike i kahi hui pūnaewele a i ʻole kahi hui kūloko no ke kākoʻo.

Hiki paha i kāu hui lapaʻau ke kōkua i nā kumuwaiwai.