ʻO Myeloid Leukemia maʻi: he aha ia, nā kumu, nā hōʻailona a me nā lāʻau

Anter

• He aha nā hōʻailona
• Nā kumu kūpono
• He aha nā mea pilikia
• He aha ke kuhi
• Pehea e hana ai i ka lāʻau
• 1. Nā Lapaʻau
• 2. Ka hoʻoneʻe iwi ʻana o ka iwi
• 3. ʻO Chemotherapy
• 4. Hoʻomaʻo Interferon

ʻO ka Myeloid Leukemia Chronic (CML) kahi ʻano laha ʻole, hoʻoilina hoʻoilina o ke koko e ulu ana ma muli o ka loli o nā genes pūnaewele, e hoʻokaʻawale koke aku ma mua o nā hunaola maʻamau.

Hiki ke mālama ʻia ka lāʻau me ka lāʻau, ka hoʻoneʻe iwi o ka iwi, chemotherapy a i ʻole ma o nā lāʻau olaola, e like me ke koʻikoʻi o ka pilikia a i ʻole ke kanaka e mālama ʻia.

ʻO nā kūlana o ka hoʻōla he kiʻekiʻe loa ia, akā hiki ke loli e like me ke ʻano o ka ulu ʻana o ka maʻi, a me ka makahiki a me ka olakino olakino o ka mea i hoʻopilikia ʻia. ʻO ka maʻamau, ʻo ka mālama ʻana me ka helu hoʻōla maikaʻi ʻoi aku ka transplant o ka iwi iwi, akā ʻaʻole paha he nui ka poʻe e hele i kēlā lapaʻau.

He aha nā hōʻailona

ʻO nā hōʻailona a me nā ʻōuli e hiki ke hana ʻia i ka poʻe me Chronic Myeloid Leukemia:

• Kahe pinepine ʻana;
• Māluhiluhi;
• Fiva;
• Ka hōʻemi kaumaha me ke kumu ʻole;
• Ka nele o ka makemake;
• ʻEha ma lalo o nā iwi ʻaoʻao, ma ka ʻaoʻao hema;
• Pallor;
• ʻO ka sweating nui loa i ka pō.

ʻAʻole hōʻike koke kēia maʻi i nā hōʻailona a me nā hōʻailona maopopo i ka wā mua a ʻo ia ke kumu e hiki ai ke noho me kēia maʻi no nā mahina a i ʻole mau makahiki me ka ʻike ʻole o ka mea iā ia.

Nā kumu kūpono

Loaʻa i nā pūnaewele kanaka he 23 mau paukū chromosome, kahi i loaʻa iā DNA me nā genes e komo i ka kaohi o nā hunaola i loko o ke kino. I ka poʻe me Chronic Myeloid Leukemia, i nā kele koko, hoʻololi kahi ʻāpana o ka chromosome 9 i nā wahi me ka chromosome 22, e hana ana i kahi chromosome pōkole loa 22, i kapa ʻia ʻo chromosome Philadelphia a me kahi chromosome lōʻihi loa 9.

Hoʻokumu kēia chromosome ʻo Philadelphia i gen hou, a me nā ʻāpana ma ka chromosome 9 a me 22 a laila hana i kahi moʻokūʻauhau hou i kapa ʻia ʻo BCR-ABL, kahi e loaʻa ai nā ʻōkuhi e haʻi i kēia cell abnormal hou e hana i kahi nui o nā protein i kapa ʻia ʻo tyrosine kinase. hiki i ka hoʻokumu ʻia ʻana o ka maʻi ʻaʻai e ka ʻae ʻana i nā hunaola e ulu i waho o ka kaohi, e hōʻino ana i ka iwi iwi.

He aha nā mea pilikia

ʻO nā kumu i hiki ke hoʻonui i ka makaʻu o ka hoʻomōhala ʻana i ka Chronic Myeloid Leukemia he ʻelemakule, he kāne a hōʻike ʻia i ka radiation, e like me radiation therapy i hoʻohana ʻia e mālama ai i kekahi ʻano maʻi ʻaʻai.

He aha ke kuhi

ʻO ka mea maʻamau, ke manaʻo ʻia kēia maʻi, a i ʻole a i ʻole a i ʻole inā i kekahi mau manawa e kū ai kahi hōʻailona, ​​hana ʻia kahi diagnostic kahi i loko o kahi hoʻokolohua kino, e like me ka nānā ʻana i nā hōʻailona koʻikoʻi a me ke kahe o ke koko, palpation o nā lymph node, ka maʻi a me ka ʻōpū kahi ala e ʻike ai i kahi kūpono kūpono ʻole.

Hoʻohui, he mea maʻamau no ke kauka e kuhikuhi i nā hoʻokolohua koko, biopsy kahi iwi o ka iwi iwi, i lawe mau ʻia mai ka iwi pūhaka, a me nā hoʻokolohua loea hou aku, e like me ka fluorescent in situ hybridization analysis a me ka polymerase chain reaction test, ka mea e kālailai ai. ʻo ke koko a i ʻole nā ​​iwi o ka iwi no ka loaʻa ʻana o ka chromosome Philadelphia a i ʻole ka ʻāpana BCR-ABL.

Pehea e hana ai i ka lāʻau

ʻO ka pahuhopu o ka mālama ʻana i kēia maʻi ʻo ka hoʻopau ʻana i nā hunaola koko i loaʻa ka ʻaoʻao ʻokoʻa, ka mea e hana ai i kahi nui o nā hunaola koko ʻokoʻa. No kekahi poʻe ʻaʻole hiki ke hoʻopau i nā keena maʻi āpau, akā hiki i ka lapaʻau ke kōkua i ke kala ʻana i ka maʻi.

1. Nā Lapaʻau

Hiki ke hoʻohana ʻia nā lāʻau lapaʻau e ālai i ka hana o ka tyrosine kinase, e like me Imatinib, Dasatinib, Nilotinib, Bosutinib a me Ponatinib, ʻo ia ka maʻamau o ka mālama mua ʻana no ka poʻe me kēia maʻi.

ʻO nā hopena i hiki ke hopena ʻia e kēia mau lāʻau lapaʻau ka pehu ʻana o ka ʻili, nausea, nā puʻupuʻu puʻupuʻu, māluhiluhi, ʻōpū a me nā hopena o ka ʻili.

2. Ka hoʻoneʻe iwi ʻana o ka iwi

ʻO ka hoʻoneʻe iwi iwi wale nō ke ʻano o ka mālama ʻana e hōʻoiaʻiʻo ai i kahi ola mau loa no Chronic Myeloid Leukemia. Eia nō naʻe, hoʻohana wale ʻia kēia hana i ka poʻe i pane ʻole i nā ʻano lāʻau ʻē aʻe no ka mea hōʻike kēia ʻano i nā pilikia a hiki ke alakaʻi i nā pilikia koʻikoʻi.

3. ʻO Chemotherapy

ʻO Chemotherapy kekahi lāʻau lapaʻau e hoʻohana ākea ʻia i nā hihia o Chronic Myeloid Leukemia a ʻo nā hopena ʻaoʻao e pili ana i ke ʻano o ka lāʻau i hoʻohana ʻia i ka lāʻau. E ʻike i nā ʻano chemotherapy a pehea e hana ai.

4. Hoʻomaʻo Interferon

Hoʻohana nā mea olaolaola i ka ʻōnaehana pale o ke kino e kōkua i ke kaua ʻana i ka maʻi ʻaʻai e hoʻohana ana i ka protein i kapa ʻia interferon, ka mea e kōkua ai e hōʻemi i ka ulu ʻana o nā pūpū tumora. Hiki ke hoʻohana i kēia hana i nā hihia kahi e hana ʻole ai nā lāʻau ʻē aʻe a i ʻole i ka poʻe hiki ʻole ke lawe i nā lāʻau ʻē aʻe, e like me nā wahine hāpai.

ʻO nā hopena maʻa mau i kēia mālama ʻana ka luhi, ke kuni, nā ʻōuli e like me ka flu a me ka pohō kaumaha.