Ka maʻi o Paget o ka umauma: he aha ia, nā ʻōuli a me nā lāʻau

Anter

• Nā ʻōuli o ka maʻi o Paget o ka umauma
• Pehea e hana ʻia ai ke kuhi
• ʻIʻike ʻokoʻa
• Hoʻomaʻo no ka maʻi o Paget o ka umauma

ʻO ka maʻi o Paget o ka umauma, a i ʻole DPM, kahi ʻano laha ʻole o ka maʻi umauma e pili pinepine ʻia i nā ʻano ʻē aʻe o ka maʻi ʻaʻai umauma. ʻAʻole ʻike ʻia kēia maʻi i nā wahine ma mua o ka makahiki 40, ʻike pinepine ʻia ma waena o nā makahiki 50 a me 60. ʻOiai he kakaikahi, hiki i ka maʻi o ka umauma ʻo Paget ke ala aʻe i nā kāne.

ʻO ka hōʻailona o ka maʻi o Paget o ka umauma i hana ʻia e ka mastologist ma o nā hoʻokolohua diagnostical a me ka loiloi ʻana i nā ʻōuli, e like me ka ʻeha o ka nipple, ka huhū a me ka desquamation kūloko a me ka ʻeha a me ka ʻeha ma ka nipple.

Nā ʻōuli o ka maʻi o Paget o ka umauma

Hana ʻia nā ʻōuli o ka maʻi o Paget i hoʻokahi umauma a ʻoi aku ka pinepine i nā wahine ma mua o 50, ʻo ka mea nui:

• Hoʻonāukiuki kūloko;
• ʻEha ma ka nipple;
• Desquamation o ka māhele ʻāina;
• Hoʻololi o ke kinona o ka nipple;
• ʻEha a ʻili hoʻi i ka nipple;
• Kukuna wela i ka wahi;
• Paakiki o ka areola;
• ʻEleʻele o ka pūnaewele, i nā hihia rarer.

I nā kūlana holomua o ka maʻi o Paget, hiki i ke komo ʻana o ka ʻili a puni ka areola, me ka retraction, inversion a me ka ulceration o ka nipple, no laila he mea nui e hoʻomaka koke ka lapaʻau ʻana i ka wā hiki.

ʻO ke kauka kūpono loa e kuhikuhi a alakaʻi i ka mālama ʻana i ka maʻi o Paget o ka umauma ʻo ka mastologist, akā ʻo ka ʻike a me ka mālama ʻana i ka maʻi e hiki ke koi ʻia e ka dermatologist a me ka gynecologist. He mea nui e hana koke ʻia ke kuhi, ʻoiai kēia ala e hiki ai ke mālama pono, me nā hopena maikaʻi.

Pehea e hana ʻia ai ke kuhi

ʻO ke kuhi ʻana i ka maʻi o Paget o ka umauma i hana ʻia e ke kauka ma o ka loiloi ʻana i nā ʻōuli a me nā ʻano o ka umauma o ka wahine, me ka hoʻohui ʻana i nā hoʻokolohua kiʻi, e like me ka ultrasound umauma a me ke kiʻi ʻana o ka resonance ʻumeʻume, e laʻa me. Hoʻohui ʻia, hōʻike ʻia ka mammography i mea e nānā ai hoʻi i ka loaʻa ʻana o nā puʻupuʻu a i ʻole microcalcification i ka umauma i hōʻailona ʻia o ka carcinoma invasive.

Ma waho aʻe o nā hoʻokolohua kiʻi ʻana, noi pinepine ke kauka i kahi biopsy o ka nipple, i mea e hōʻoia ai i nā ʻano o nā hunaola, i hoʻohui ʻia me ka hoʻokolohua immunohistochemical, i kūlike i kahi ʻano o ka hoʻokolohua hoʻokolohua kahi e hōʻoia ʻia ai ke alo a me ka ʻole o nā antigens. hiki iā ia ke kuhi i ka maʻi, e like me AE1, AE3, CEA a me EMA i kūpono i ka maʻi o Paget o ka umauma.

ʻIʻike ʻokoʻa

ʻO ka ʻike ʻokoʻa o ka maʻi o Paget o ka umauma i hana nui ʻia ʻo psoriasis, carcinoma basal cell a me eczema no ka laʻana, ʻokoʻa ʻia me ka mea hope loa e ka unilateral a me ka ʻūlū liʻiliʻi. Hiki ke mālama ʻia i nā hōʻike ʻokoʻa e lawe ana i ka pane i ka therapy, ʻoiai ma ka maʻi ʻo Paget, hiki i ka mālama kumuhana ke hoʻokuʻu i nā hōʻailona akā ʻaʻohe hopena paʻa, me ka hoʻi hou ʻana.

Hoʻohui ʻia, pono e hoʻokaʻawale ʻia ka maʻi o ka umauma ʻo Paget, ke pigmented, mai ka melanoma, a hana ʻia kēia ma o ka hoʻokolohua histopathological, i hana ʻia e loiloi i nā hunaola umauma, a me ka immunohistochemistry, kahi ia o ka HMB-45, MelanA a me S100 antigens i ka melanoma a me ka ʻole o nā antigens AE1, AE3, CEA a me EMA, i loaʻa mau i ka maʻi o Paget o ka umauma.

Hoʻomaʻo no ka maʻi o Paget o ka umauma

ʻO ka lāʻau i hōʻike ʻia e ke kauka no ka maʻi o Paget o ka umauma he mastectomy maʻamau ia e ukali ʻia e nā wā chemotherapy a i ʻole radiation therapy, no ka mea pili pinepine kēia maʻi i ka carcinoma invasive. I nā hihia liʻiliʻi, hōʻike ʻia ka wehe ʻana o ka ʻokiʻoki o ka wahi ʻeha, e mālama ana i ke koena o ka umauma. He mea nui ka ʻike mua e pale ai ʻaʻole wale ka holomua o ka maʻi, akā ʻo ka lāʻau lapaʻau hoʻi.

I kekahi mau hihia, hiki i ke kauka ke koho e hoʻokō i ka lāʻau me ka hōʻoia ʻole ʻole o ka hōʻailona, ​​e hōʻike ana i ka hoʻohana ʻana o nā lāʻau kumuhana. ʻO ka pilikia e pili ana i kēia ʻano hana hiki i kēia mau lāʻau ke hōʻoluʻolu i nā ʻōuli, akā ʻaʻole lākou e keakea i ka holomua o ka maʻi.