He aha ka Lymphoma B-Cell?

Anter

• He aha nā subtypes o ka B-cell lymphoma?
• Ke hoʻokū nei
• He aha nā hōʻailona?
• Pehea e mālama ʻia ai?
• Pāhawewe
• ʻO Chemotherapy
• Hoʻoikaika pale maʻi
• Ke kuʻi ʻōnaʻi ʻōnaeho
• Aia paha nā pilikia?
• He aha ke ʻano o ka hoʻōla?
• Outlook

Hōʻike Overview

ʻO Lymphoma kahi ʻano o ka maʻi ʻaʻai e hoʻomaka i nā lymphocytes. ʻO nā lymphocytes nā hunaola o ka ʻōnaehana pale. ʻO Hodgkin's a me non-Hodgkin's lymphoma nā ʻano nui ʻelua o ka lymphoma.

ʻO ka lymphoma T-cell a me ka B-cell lymphoma ʻelua mau ʻano o ka lymphoma non-Hodgkin. Aia kekahi ʻano laha ʻole i kapa ʻia ʻo NK-cell lymphoma.

Ma waena o ka poʻe me ka limfoma non-Hodgkin, ma kahi o 85 pākēneka he B-cell lymphoma.

Hoʻokumu ʻia ka mālama ʻana no nā lymphomas B-cell ma ka subtype kikoʻī a me ke kahua o ka maʻi.

He aha nā subtypes o ka B-cell lymphoma?

Nui a hewahewa nā subtypes o ka lymphoma B-cell, e ulu lohi ana (molowa) a e ulu wikiwiki ana (agresive), me:

Ke hoʻokū nei

Hoʻokomo ʻia ka maʻi ʻaʻai e like me ka lōʻihi i hoʻolaha ai mai ka pūnaewele kumu. Hoʻokumu ʻia ka lymphoma o Non-Hodgkin mai ka 1 a i ka 4, me 4 ka mea i holomua.

He aha nā hōʻailona?

Hoʻohālikelike nā ʻōuli e like me ke ʻano o ka lymphoma B-cell a pehea kona holomua. Eia kekahi o nā hōʻailona nui:

• pehu nā lymph node i kou ʻāʻī, ʻūpā lima, a i ʻole ke ʻū
• ʻeha o ka ʻōpū a pehu paha
• ʻeha ka umauma
• ʻūhā
• nā pilikia hanu
• ka wela fiva a me ka hou ka pō
• Kaumaha emi
• luhi

Pehea e mālama ʻia ai?

ʻO kekahi ʻano o ka lymphoma i asymptomat a palaka ʻaʻole pono e koi ʻia i ka lāʻau. Koi paha kāu kauka i ka mea i ʻike ʻia ʻo "ke kiaʻi kiaʻi." ʻO ia ka mea e hāhai ʻoe i kēlā me kēia mau mahina e hōʻoia i ka hele ʻole o ka maʻi ʻaʻai. I kekahi mau hihia, hiki ke hoʻomau i kēia no nā makahiki.

Hiki ke hoʻomaka i ka mālama ʻana ke hōʻike ʻia nā hōʻailona a i ʻole inā he mau hōʻailona o ka holomua o ka maʻi. Hoʻohui pinepine ka lymphoma B-cell i kahi hui o nā lapaʻau, i hiki ke loli i ka manawa.

Pāhawewe

Ke hoʻohana nei i nā kaola ikaika ikaika, hoʻohana ʻia ka radiation therapy e pepehi i nā hunaola maʻi ʻaʻai a hoʻoliʻiliʻi i nā tumors. Pono ia e moe mālie i ka papa ʻaina ke kuhikuhi ʻia nā kaola i kahi kiko kikoʻī i kou kino.

No ka lohi o ka ulu ʻana, localized lymphoma, radiation therapy paha e pono ai ʻoe.

Hiki i nā hopena ke hoʻopili i ka luhi a me ka huhū o ka ʻili.

ʻO Chemotherapy

ʻO Chemotherapy kahi ʻōnaehana ʻōnaehana i hiki ke hāʻawi ʻia i ka waha a i ʻole ke aniani. Hiki ke hoʻōla ʻia kekahi lymphomas B-cell ikaika me ka chemotherapy, keu hoʻi i ka maʻi ma mua.

ʻO DLBCL kahi ʻano ulu wikiwiki i hiki ke mālama ʻia me kahi regema chemotherapy i kapa ʻia ʻo CHOP (cyclophosphamide, doxorubicin, vincristine, a me prednisone). Ke hāʻawi ʻia me ka monoclonal antibody rituximab (Rituxan), kapa ʻia ʻo R-CHOP. Hāʻawi pinepine ʻia i nā pōʻai i kekahi mau pule i kaawale. He paʻakikī ia i ka puʻuwai, no laila ʻaʻole ia he koho inā loaʻa iā ʻoe nā pilikia puʻuwai preexisting.

Hiki i nā hopena o ka chemotherapy ke hoʻopili i ka nausea, ka luhi, a me ka nalo ʻana o ka lauoho.

Hoʻoikaika pale maʻi

Kōkua nā lāʻau biologic i kāu ʻōnaehana pale pale i ka maʻi ʻaʻai. Hoʻokumu ʻo Rituximab i nā protein ma ka ʻili o nā B-cells, e maʻalahi ai no ka ʻōnaehana pale e ʻike a luku iā lākou. Ma ka hoʻemi ʻana i ka helu o nā maʻi maʻi B a me ke olakino, hoʻonāukiuki ka lāʻau i kou kino e hana i nā B-cell olakino hou. Hoʻemi iki kēia i ka hoʻi hou ʻana o ka maʻi ʻaʻai.

ʻO nā lāʻau Radioimmunotherapy, e like me ibritumomab tiuxetan (Zevalin), hana ʻia e nā monoclonal antibodies e hāpai i nā isotop radioactive. Kōkua ka lāʻau i nā mea ʻino e hoʻopili i nā hunaola maʻi ʻaʻai no ka lawe pololei ʻana o ka pāhawewe.

Hiki i nā hopena o ka immune therapy ke hoʻopili i nā helu o ke koko keʻokeʻo haʻahaʻa, luhi, a me nā maʻi.

Ke kuʻi ʻōnaʻi ʻōnaeho

Hoʻopili kahi transplant cell stem i kāu momona o ka iwi me ka momona o kahi mea hāʻawi maikaʻi. ʻO ka mea mua, pono ʻoe i ka chemotherapy kiʻekiʻe a i ʻole ka radiation e hoʻopau i kāu ʻōnaehana pale, luku i nā pūnaʻi maʻi ʻaʻa, a hana i kahi no ka momona hou. I mea e kūpono ai, pono ʻoe i ke olakino e kū i kēia mālama.

Hiki i nā hopena ʻaoʻao ke hoʻopili i nā maʻi, anemia, a me ka hōʻole ʻana i ka iwi iwi hou.

Aia paha nā pilikia?

Hoʻonawaliwali ʻo Lymphomas i kou ʻōnaehana pale, e hoʻonui ai iā ʻoe i ka maʻi i nā maʻi. Hiki i kekahi mau lāʻau no ka lymphoma ke kumu i nā pilikia e like me:

• infertility
• puʻuwai, akemāmā, hakuʻala, a me ka maʻi thyroid
• diabetes
• maʻi ʻaʻai ʻelua

Hiki i nā lymphomas B-cell ke ulu a pāhola i nā meaola mamao.

He aha ke ʻano o ka hoʻōla?

Hiki ke hoʻōla ʻia kekahi ʻano o nā lymphomas B-cell. Hiki i ka mālama ʻana ke hoʻolohi i ka holomua i kekahi. Inā ʻaʻohe hōʻailona o ka maʻi ʻaʻai ma hope o kāu lapaʻau mua, ʻo ia hoʻi ke kala nei ʻoe. Pono ʻoe e hāhai i mau makahiki hou e nānā no ka hoʻi hou ʻana.

Outlook

ʻO ka nui o ke ola ʻana he ʻelima mau makahiki e ola ai no ka lymphoma non-Hodgkin he 70 pakeneka. Hoʻololi kēia i nā mea he nui e like me ke ʻano o ka lymphoma B-cell a me ke kahua ma ke kuhi. ʻO nā manaʻo ʻē aʻe kou makahiki a me ke olakino holoʻokoʻa.

ʻO kahi laʻana, hiki ke mālama ʻia ʻo DLBCL ma kahi o ka hapalua o ka poʻe i loaʻa. ʻO ka poʻe i hoʻomaka i ka mālama ʻana i nā wā ma mua he ʻoi aku ka maikaʻi o ka nānā ma mua o ka poʻe i loaʻa i ka maʻi hope.

Hiki i kāu kauka ke hāʻawi iā ʻoe me kāu wānana pilikino e pili ana i kāu pili olakino piha.