E nīnau i ka mea loea: Ke mālama ʻana a me ka mālama ʻana i ka Urticaria Idiopathic maʻi
Anter
- 1. Ua pau ka hana ʻana i nā Antihistamines e kaohi i kaʻu mau ʻōuli. He aha kaʻu mau koho ʻē aʻe?
- 2. He aha nā kalima a i ʻole nā hamo e pono ai iaʻu e hoʻohana e mālama i ka makika mau mai CIU?
- 3. E hala aku ana paha kaʻu CIU?
- 4. He aha nā mea noiʻi ʻike e pili ana i ke kumu o ke CIU?
- 5. Aia kekahi mau hoʻololi meaʻai e pono ai iaʻu e hoʻoponopono i kaʻu CIU?
- 6. He aha nā ʻōlelo aʻoaʻo āu e loaʻa ai no ka ʻike ʻana i nā mea kāhea?
- 7. He aha nā ʻano lāʻau e hiki ai iaʻu ke hoʻāʻo?
- 8. He aha nā ʻano lāʻau e hiki ai i kaʻu kauka ke kuhikuhi?
1. Ua pau ka hana ʻana i nā Antihistamines e kaohi i kaʻu mau ʻōuli. He aha kaʻu mau koho ʻē aʻe?
Ma mua o ka hāʻawi ʻana i nā antihistamines, ʻike mau wau i ka hoʻonui ʻana o kaʻu mau mea maʻi i kā lākou ana. Palekana ia e lawe a i ʻehā mau manawa i ka lā i koi ʻia no kēlā me kēia lā o nā antihistamines ʻole. ʻO nā laʻana me loratadine, cetirizine, fexofenadine, a i ʻole levocetirizine.
Ke hāʻule ʻole nā lāʻau lapaʻau kiʻekiʻe, non-sedating antihistamines, ʻo nā hana aʻe e komo pū me nā antihistamines sedating e like me hydroxyzine a me doxepin. A i ʻole, e hoʻāʻo mākou i nā mea pale H2, e like me ka ranitidine a me ka famotidine, a me nā mea leukotriene e like me zileuton.
No nā hives paʻakikī e mālama ʻia, huli pinepine wau i kahi lāʻau hoʻōla i kapa ʻia ʻo omalizumab. Loaʻa iā ia ka pōmaikaʻi o ka nonsteroidal a maikaʻi loa i ka hapanui o nā mea maʻi.
ʻO ka urticaria idiopathic maʻi mau loa (CIU) kahi maʻi maʻi imunologically mediated. No laila, i nā hihia nui loa, hiki paha iaʻu ke hoʻohana i nā pale pale ʻōnaehana e like me cyclosporine.
2. He aha nā kalima a i ʻole nā hamo e pono ai iaʻu e hoʻohana e mālama i ka makika mau mai CIU?
ʻO ka makaʻu mai CIU ma muli o kahi hoʻokuʻu histamine kūloko. Nā ʻākena kumuhana - e like me nā antihistamines kumuhana - ka nui o ka hopena i ka mālama ʻana i nā ʻōuli.
E lawe i nā ua mehana pinepine a kau i nā wai ʻoluʻolu a me nā anuanu ke ʻā ka hives a ʻeha loa. Kōkua paha kahi steroid topical. Eia nō naʻe, nā antihistamines waha a me ka omalizumab a i ʻole nā mea hoʻololi ʻē aʻe i nā ʻōnaehana pale e hāʻawi i kahi hoʻomaha hou aku.
3. E hala aku ana paha kaʻu CIU?
ʻAe, kokoke i nā hihia āpau o ka urticaria idiopathic mau loa e hoʻoholo hope loa. Eia nō naʻe, ʻaʻole hiki ke wānana i ka wā e hiki ai kēia.
E loli pū ana ka paʻakikī o ka CIU me ka manawa, a pono paha ʻoe i nā pae o ka hoʻōla i nā manawa like ʻole. Aia kekahi makaʻu mau o ka CIU ke hoʻi hou ke hele i ke kala.
4. He aha nā mea noiʻi ʻike e pili ana i ke kumu o ke CIU?
Nui a hewahewa nā manaʻo i waena o nā mea noiʻi e pili ana i ke kumu o ka CIU. ʻO ke kumumanaʻo nui loa ʻo CIU kahi ʻano like autoimmune.
I ka poʻe me CIU, ʻike pinepine mākou i nā autoantibodies i kuhikuhi ʻia i nā keena e hoʻokuʻu i ka histamine (mast cells and basophils). Hoʻohui ʻia, loaʻa pinepine kēia mau kānaka i nā maʻi autoimmune e like me ka maʻi thyroid.
ʻO kekahi kumumanaʻo aia he mau mea kūkākūkā kikoʻī i ka serum a i ʻole ka plasma o nā poʻe me CIU. Hoʻoulu kēia mau mea hoʻopili i nā pūnaewele mast a i ʻole nā basophil, a i ʻole pololei a pololei ʻole paha.
ʻO ka mea hope loa, aia ke "kumumanaʻo kīnā hemahema." Wahi a kēia kumumanaʻo i nā poʻe me CIU i nā kīnā i ka mast cell a i ʻole ke kālepa basophil, ka hōʻailona, a i ʻole ka hana ʻana. Ke alakaʻi nei kēia i ka hoʻokuʻu histamine nui.
5. Aia kekahi mau hoʻololi meaʻai e pono ai iaʻu e hoʻoponopono i kaʻu CIU?
ʻAʻole mākou e paipai pinepine i nā loliʻai e mālama iā CIU ʻoiai ʻaʻole hōʻike nā haʻawina i kahi pōmaikaʻi. ʻAʻole kākoʻo ʻia ka hoʻololi ʻana i ka meaʻai e ka nui o nā kuhikuhi kuʻikahi.
ʻO ka mālama ʻana i nā papaʻai, e like me ka papaʻai histamine haʻahaʻa, paʻakikī loa hoʻi e ukali. He mea nui nō hoʻi e hoʻomaopopo ʻaʻole ʻo CIU kahi hopena o kahi allergy meaʻai maoli, no laila ʻaʻole ʻike iki nā huaʻai.
6. He aha nā ʻōlelo aʻoaʻo āu e loaʻa ai no ka ʻike ʻana i nā mea kāhea?
Aia kekahi mau mea i ʻike ʻia i hiki ke hōʻeha i kāu hives. ʻO ka wela, ka wai ʻona, kaomi, ka hakakā, a me nā manaʻo kaumaha e hōʻike maikaʻi ʻia e hōʻeha i nā hōʻailona.
Hoʻohui hou, pono ʻoe e noʻonoʻo e hōʻalo i ka aspirin a me nā lāʻau anti-inflammatory nonsteroidal (NSAIDs) ʻē aʻe. Hiki iā lākou ke hoʻonāukiuki iā CIU i nā manawa he nui. Hiki paha iā ʻoe ke hoʻomau i ka lawe haʻahaʻa ʻana, aspirin pēpē ke hoʻohana ʻia e pale ai i nā kahe koko.
7. He aha nā ʻano lāʻau e hiki ai iaʻu ke hoʻāʻo?
ʻO nā antihistamines OTC non-sedating, a i ʻole nā H1 blockers, hiki ke kaohi i nā hives no ka hapanui o ka poʻe me CIU. Hoʻopili kēia mau huahana i ka loratadine, cetirizine, levocetirizine, a me fexofenadine. Hiki iā ʻoe ke lawe i ʻehā mau manawa i ka lāʻau i koi ʻia i kēlā me kēia lā me ka ʻole e hoʻomohala i nā hopena ʻaoʻao.
Hiki iā ʻoe ke hoʻāʻo i nā antihistamines sedating e pono ai, e like me diphenhydramine. Hiki i nā antihistamines H2-keʻakeʻa, e like me famotidine a me ranitidine, ke hāʻawi i kahi hoʻomaha keu.
8. He aha nā ʻano lāʻau e hiki ai i kaʻu kauka ke kuhikuhi?
I kekahi manawa, ʻaʻole hiki i nā antihistamines (nā H1 a me nā H2 blockers) ke hoʻokele i nā hives a me nā ʻōhū e pili ana me CIU. Ke hiki mai kēia, ʻoi aku ka maikaʻi o ka hana pū ʻana me kahi alerizio hōʻoiaʻiʻo ʻia e ka papa a i ʻole immunologist. Hiki iā lākou ke kuhikuhi i nā lāʻau e hāʻawi i ka kaohi ʻoi aku ka maikaʻi.
Hiki i kāu kauka ke hoʻāʻo i ka sedating ikaika, nā antihistamines i kuhikuhi mua ʻia e like me hydroxyzine a i ʻole doxepin. Hiki iā lākou ke hoʻāʻo i ka omalizumab inā ʻaʻole holo pono kēia mau lāʻau i ka mālama ʻana i kāu mau ʻōuli.
ʻAʻole mākou e paipai pinepine i nā corticosteroids waha no ka poʻe me CIU. Loaʻa kēia i ko lākou hiki i nā hopena ʻaoʻao nui. Hoʻohana ʻia nā pale pale ʻē aʻe i kekahi manawa i nā hihia koʻikoʻi, ʻaʻole hiki ke hoʻokele.
Ua loaʻa iā Marc Meth, MD, kona kekelē laepua mai ke Kula Lapaʻau ʻo David Geffen ma UCLA. Ua hoʻopau ʻo ia i kona noho ʻana ma ka Lapaʻau Kūloko ma ka Halemai ʻo Mount Sinai ma New York City. Ma hope mai ua hoʻopau ʻo ia i kahi pilina ma Allergy & Immunology ma Long Island Jewish-North Shore Medical Center. ʻO Kauka Meth i kēia manawa ma ke Kula Haumāna ma ke Kula Kauka Lapaʻau ʻo David Geffen ma UCLA a he mau kuleana kona ma Cedars Sinai Medical Center. He diplomate ʻo ia o ka Papa ʻAmelika o ka Lapaʻau Kūloko a me ka Papa ʻAmelike a me Immunology o ʻAmelika. Aia ʻo Kauka Meth ma kahi hana pilikino ma Century City, Los Angeles.