ʻO Antineutrophil Cytoplasmic Antibodies (ANCA) hōʻike
Anter
- He aha ka antineutrophil cytoplasmic antibodies (ANCA) hōʻike?
- No ke aha ia e hoʻohana ai?
- No ke aha wau e pono ai i kahi hōʻike ANCA?
- He aha ka hana i ka wā o kahi hōʻike ANCA?
- Pono wau e hana i kekahi mea e hoʻomākaukau ai no ka hoʻāʻo?
- Aia kekahi mau pilikia i ka hoʻāʻo?
- He aha ke ʻano o nā hopena?
- Aia kekahi mea ʻē aʻe e pono iaʻu e ʻike e pili ana i kahi hōʻike ANCA?
- Nā kūmole
He aha ka antineutrophil cytoplasmic antibodies (ANCA) hōʻike?
Nānā kēia hōʻike no nā antineutrophil cytoplasmic antibodies (ANCA) i loko o kou koko. ʻO nā Antibodies nā protein a kou ʻōnaehana pale e hana ai e hakakā i nā mea haole e like me nā virus a me nā bacteria. Akā hōʻeha ʻo ANCA i nā hunaola olakino i ʻike ʻia he neutrophil (kahi ʻano o ke koko keʻokeʻo) ma ke kuhi hewa. Hiki i kēia ke alakaʻi i kahi maʻi i ʻike ʻia ma ke ʻano he vasculitis autoimmune. ʻO ka vasculitis Autoimmune ke kumu o ka palahū a me ka pehu ʻana o nā kīʻaha koko.
Lawe nā kīʻaha koko i ke koko mai kou puʻuwai i kāu ʻokena, nāʻaʻaʻa, a me nā ʻōnaehana ʻē aʻe, a laila hoʻi hou. ʻO nā ʻano o nā kīʻaha koko nā aʻa, nā uaua, a me nā capillaries. Hiki ke hōʻeha i nā kīʻaha koko ke hana i nā pilikia olakino koʻikoʻi. Hoʻololi nā pilikia ma muli o ka hopena o nā kīʻaha koko a me nā ʻōnaehana o ke kino.
Aia he ʻano nui ʻelua o ANCA. Hoʻolālā kēlā me kēia i kahi protein kikoʻī i loko o nā hunaola keokeo.
- pANCA, kahi e pahuhopu nei i kahi protein i kapa ʻia ʻo MPO (myeloperoxidase)
- cANCA, kahi e pahuhopu nei i kahi protein i kapa ʻia PR3 (proteinase 3)
Hiki i ka hoʻāʻo ke hōʻike inā loaʻa iā ʻoe i hoʻokahi a i ʻole ʻelua ʻano o nā antibodies. Hiki i kēia ke kōkua i kāu lawelawe mālama ola e hōʻoia a mālama i kāu maʻi.
Nā inoa ʻē aʻe: ANCA antibodies, cANCA pANCA, cytoplasmic neutrophil antibodies, serum, anticytoplasmic autoantibodies
No ke aha ia e hoʻohana ai?
Hoʻohana pinepine ʻia kahi hōʻike ANCA e ʻike inā loaʻa iā ʻoe kahi ʻano vasculitis autoimmune. Aia nā ʻano like ʻole o kēia maʻi. Hoʻokumu lākou āpau i ka mumū a me ka pehu ʻana o nā kīʻaha koko, akā pili kēlā me kēia ʻano i nā kīʻaha koko a me nā ʻāpana o ke kino. Nā ʻano o ka vasculitis autoimmune:
- Granulomatosis me polyangiitis (GPA), i kapa ʻia ma mua ʻo Wegener's disease. Hoʻololi pinepine ia i nā akemāmā, nā puʻupaʻa, a me nā sinus.
- Polokikaitis microscopic (MPA). Hiki i kēia maʻi ke hoʻololi i nā ʻōpū i loko o ke kino, e like me nā akemāmā, nā puʻupaʻa, nā ʻōnaehana, a me ka ʻili.
- Eosinophilic granulomatosis me polyangiitis (EGPA), i kapa ʻia ma mua ʻo Churg-Strauss Syndrome. Hoʻopili pinepine kēia maʻi i ka ʻili a me nā akemāmā. Hoʻokumu pinepine ia i ka hānō.
- ʻO Polyarteritis nodosa (PAN). Hoʻopili pinepine kēia maʻi i ka puʻuwai, nā puʻupaʻa, ka ʻili, a me nā ʻōnaehana waena.
Hiki ke hoʻohana ʻia kahi hōʻike ANCA e nānā i ka mālama ʻana i kēia mau maʻi.
No ke aha wau e pono ai i kahi hōʻike ANCA?
E kauoha paha kāu mea mālama ola i kahi hōʻoia ANCA inā loaʻa iā ʻoe nā ʻōuli o ka autoimmune vasculitis. ʻO nā hōʻailona me:
- Fiva
- Ka luhi
- Kaumaha emi
- Muscle a me / a i ʻole nā ʻeha hui
Hiki paha i kāu mau ʻōuli ke hoʻopili i hoʻokahi a i ʻole nā kikoʻī kikoʻī i kou kino. ʻO nā ʻāpana maʻamau a me nā ʻōuli a lākou e hoʻopili ai:
- Nā Maka
- ʻUlaʻula
- ʻIke makapō
- Lilo o ka hihiʻo
- Pepeiao pepeiao
- Ke kani nei i nā pepeiao (tinnitus)
- Lohe hoʻolohe
- Sinus
- ʻEha Sinus
- Mū ihu
- Kiko ihu
- ʻIli
- ʻO Rashes
- ʻO nā ʻeha a ulcer paha, kahi ʻano ʻeha hohonu e lohi e hoʻōla a / a i ʻole e hoʻi mau nei
- Lungs
- Cough
- Hī pilikia
- ʻEha ʻeha
- Nā hakuʻala
- Koko i ka mimi
- Mimi hua, i kumu ʻia e ka protein i ka mimi
- ʻŌnaehana nervous
- Numbness a me tingling i nā ʻāpana like ʻole o ke kino
He aha ka hana i ka wā o kahi hōʻike ANCA?
E lawe kahi ʻoihana mālama ola i kahi laʻana koko mai kahi aa i kou lima, e hoʻohana ana i kahi nila kuʻikuʻi. Ma hope o ka hoʻokomo ʻia ʻana o ka nila, e hōʻiliʻili ʻia kahi koko liʻiliʻi i loko o kahi pahu hoʻāʻo a ipu paha. Hiki paha iā ʻoe ke ʻoni iki i ka wā e hele ai a kuʻi paha ka nila. Lōʻihi kēia ma mua o ʻelima mau minuke.
Pono wau e hana i kekahi mea e hoʻomākaukau ai no ka hoʻāʻo?
ʻAʻole pono ʻoe i kahi hoʻomākaukau kūikawā no kahi hōʻike ANCA.
Aia kekahi mau pilikia i ka hoʻāʻo?
ʻAʻohe liʻiliʻi loa i ka hōʻoia ʻana o ke koko. Loaʻa paha iā ʻoe ka ʻeha a ʻeha paha ma kahi o ka nila i hoʻokomo ʻia ai, akā ʻo ka hapa nui o nā ʻōuli e hele wikiwiki aku.
He aha ke ʻano o nā hopena?
Inā maikaʻi ʻole kāu mau hopena, ʻo ia hoʻi ʻaʻole paha kāu mau hōʻailona ma muli o ka vasculitis autoimmune.
Inā maikaʻi kāu mau hopena, manaʻo paha ia he autoimmune vasculitis kāu. Hiki iā ia ke hōʻike inā loaʻa nā cANCA a i ʻole nā pANCA. Hiki i kēia ke kōkua i ka hoʻoholo ʻana i kāu ʻano vasculitis.
ʻAʻohe kumu o nā ʻohā i loaʻa, pono paha ʻoe i kahi hoʻokolohua hou aʻe, i ʻike ʻia he biopsy, e hōʻoia i ke kuhi. ʻO kahi biopsy kahi hana e lawe i kahi liʻiliʻi o nā kiko a i ʻole nā pūnaewele no ka hoʻāʻo ʻana. E kauoha paha kāu mea mālama ola i nā hoʻokolohua hou aʻe e ana i ka nui o ka ANCA i kou koko.
Inā mālama ʻia ʻoe i kēia manawa no ka vasculitis autoimmune, hōʻike paha kāu mau hopena i ka hopena o kāu lāʻau.
Inā he mau nīnau kāu e pili ana i kāu hopena, e kamaʻilio me kāu kauka olakino.
E aʻo hou aʻe e pili ana i nā hoʻokolohua hoʻokolohua, nā pae kuhikuhi, a me ka hoʻomaopopo ʻana i nā hopena.
Aia kekahi mea ʻē aʻe e pono iaʻu e ʻike e pili ana i kahi hōʻike ANCA?
Inā hōʻike kāu hopena ANCA he autoimmune vasculitis kāu, aia kekahi mau ala e mālama a mālama ai i kēia ʻano. Hiki i nā mālama ke hoʻopili i nā lāʻau lapaʻau, nā hoʻoponopono e hemo iki ai nā ANCA mai kou koko, a me / a i ʻole ke ʻoki kino.
Nā kūmole
- Allina Health [Pūnaewele]. Minneapolis: Health Allina; Ana C-ANCA; [helu ʻia 2019 Mei 3]; [ma kahi o 3 pale]. Loaʻa mai: https://account.allinahealth.org/library/content/49/150100
- Allina Health [Pūnaewele]. Minneapolis: Health Allina; Ana P-ANCA; [helu ʻia 2019 Mei 3]; [ma kahi o 3 pale]. Loaʻa mai: https://account.allinahealth.org/library/content/49/150470
- Ke Kalinika ʻo Cleveland [Pūnaewele]. Cleveland (OH): Ke Kula Nui ʻo Cleveland; c2019. Ulcer wāwae a me nā wāwae; [i helu ʻia 2019 Mei 3]; [ma kahi o 3 pale]. Loaʻa mai: https://my.clevelandclinic.org/health/diseases/17169-leg-and-foot-ulcer
- Nā Hoʻokolohua Lab ma ka Pūnaewele [Pūnaewele]. Wakinekona D.C: ʻAmelika Hui Pū ʻIa no ka Chemical Clinical; c2001–2019. Nā ANCA / MPO / PR3 Antibodies; [hoʻohou 2019 Apr 29; i helu ʻia ʻo 2019 Mei 3]; [ma kahi o 2 pale]. Loaʻa mai: https://labtestsonline.org/tests/ancampopr3-antibodies
- Nā Hoʻokolohua Lab ma ka Pūnaewele [Pūnaewele]. Wakinekona D.C .: ʻAmelika Hui Pū ʻIa no ka Chemical Clinical; c2001–2019. Biopsy; [hoʻohou 2017 Jul 10; i helu ʻia ʻo 2019 Mei 3]; [ma kahi o 2 pale]. Loaʻa mai: https://labtestsonline.org/glossary/biopsy
- Nā Hoʻokolohua Lab ma ka Pūnaewele [Pūnaewele]. Wakinekona D.C .: ʻAmelika Hui Pū ʻIa no ka Chemical Clinical; c2001–2019. Vasculitis; [hoʻohou 2017 Sep 8; i helu ʻia ʻo 2019 Mei 3]; [ma kahi o 2 pale]. Loaʻa mai: https://labtestsonline.org/conditions/vasculitis
- Mansi IA, Opran A, Rosner F. ANCA-Associated Small-Vessel Vasculitis. Am Kauka Lapaʻau [Pūnaewele]. 2002 Apr 15 [helu ʻia 2019 Mei 3]; 65 (8): 1615–1621. Loaʻa mai: https://www.aafp.org/afp/2002/0415/p1615.html
- Mayo Laboratories Clinic [Pūnaewele]. Mayo Foundation no ka Hoʻomaʻamaʻa Lapaʻau a me ka noiʻi; c1995–2019. Hōʻoia ID: ANCA: Cytoplasmic Neutrophil Antibodies, Serum: Clinical a me Interpretive; [helu ʻia 2019 Mei 3]; [ma kahi o 4 pale]. Loaʻa mai: https://www.mayocliniclabs.com/test-catalog/Clinical+and+Interpretive/9441
- National Heart, Lung, and Blood Institute [Pūnaewele]. Bethesda (MD): Ke Keʻena ʻOihana Ola a me nā lawelawe kanaka; Nā ho'āʻo koko; [helu ʻia 2019 Mei 3]; [ma kahi o 3 pale]. Loaʻa mai: https://www.nhlbi.nih.gov/health-topics/blood-tests
- National Heart, Lung, and Blood Institute [Pūnaewele]. Bethesda (MD): Ke Keʻena ʻOihana Ola a me nā lawelawe kanaka; Vasculitis; [helu ʻia 2019 Mei 3]; [ma kahi o 2 pale]. Loaʻa mai: https://www.nhlbi.nih.gov/health-topics/vasculitis
- Radice A, Sinico RA. Antineutrophil Cytoplasmic Antibodies (ANCA). Autoimmunity [Pūnaewele]. 2005 Feb [helu ʻia 2019 Mei 3]; 38 (1): 93-103. Loaʻa mai: https://www.ncbi.nlm.nih.gov/pubmed/15804710
- UNC Kidney Center [Pūnaewele]. Chapel Hill (NC): UNC Kidney Center; c2019. ANCA Vasculitis; [hōʻano hou ʻia 2018 Sep; i helu ʻia ʻo 2019 Mei 3]; [ma kahi o 3 pale]. Loaʻa mai: https://unckidneycenter.org/kidneyhealthlibrary/glomerular-disease/anca-vasculitis
ʻAʻole pono e hoʻohana i ka ʻike ma kēia pūnaewele i pani no ka mālama olakino ʻoihana a ʻōlelo aʻoaʻo paha. Kāhea aku i ka mea mālama ola inā he nīnau kāu e pili ana i kou olakino.