ʻO Thalidomide

Anter

• Ma mua o ka lawe ʻana i thalidomide,
• Hoʻokumu paha ʻo Thalidomide i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

ʻO ka makaʻu i nā kīnā hānau hānau weliweli a weliweli hoʻi i hoʻokumu ʻia e thalidomide.

No nā poʻe āpau e lawe ana i ka thalidomide:

ʻAʻole pono e lawe ʻia ʻo Thalidomide e nā wahine hāpai a i ʻole hiki ke hāpai i ka wā e lawe ana i kēia lāʻau. ʻOiai kahi hoʻokahi o ka thalidomide i lawe ʻia i ka wā o ka hāpai ʻana e hiki ai ke hōʻeha i nā hānau hānau koʻikoʻi (nā pilikia o ke kino i ka pēpē i ka wā hānau) a i ʻole ka make ʻana o ka pēpē i hānau ʻole ʻia. ʻO kahi papahana i kapa ʻia ʻo Thalidomide REMS^® (i ʻike ʻia ma ke ʻano he ʻōnaehana no ka Haʻawina Thalidomide a me ka palekana e kuhikuhi ana [S.T.E.P.S.^®]) ua ʻae ʻia e ka Food and Drug Administration (FDA) e hōʻoia i ka lawe ʻole ʻana o nā wahine hāpai i ka thalidomide a ʻaʻole hāpai nā wahine i ka lawe ʻana i ka thalidomide. ʻO nā kānaka āpau i kuhikuhi ʻia i ka thalidomide, me nā kāne a me nā wahine ʻaʻole hiki ke hāpai, pono e hoʻopaʻa inoa ʻia me Thalidomide REMS^®, loaʻa kahi palapala inoa thalidomide mai ke kauka i hoʻopaʻa inoa ʻia me Thalidomide REMS^®, a hoʻopiha ʻia ke kuhikuhi ma kahi kauka lāʻau i hoʻopaʻa inoa ʻia me Thalidomide REMS^® i mea e loaʻa ai kēia lāʻau.

Pono ʻoe e ʻike i kāu kauka i kēlā me kēia mahina i kāu mālama ʻana e kamaʻilio e pili ana i kou ʻano a me nā hopena ʻē aʻe āu e ʻike nei. I kēlā me kēia kipa, hiki i kāu kauka ke hāʻawi iā ʻoe i kahi lāʻau lapaʻau a hiki i kahi lako o nā lā he 28 mau lā me ka hoʻopiha ʻole. Pono ʻoe e hoʻopiha i kēia kuhikuhi i loko o 7 mau lā.

Mai hāʻawi i ke koko i ka wā e lawe ana ʻoe i thalidomide a no 4 mau pule ma hope o kāu lapaʻau ʻana.

Mai hoʻokaʻawale i ka thalidomide me kekahi mea ʻē aʻe, ʻoiai kekahi i loaʻa i nā hōʻailona like me ʻoe.

No nā wahine e lawe nei i ka thalidomide:

Inā hiki iā ʻoe ke hāpai, pono ʻoe e hoʻokō i kekahi mau koi i ka wā o kāu mālama ʻana me thalidomide. Pono ʻoe e hoʻokō i kēia mau koi inā loaʻa iā ʻoe ka mōʻaukala o ka hiki ʻole ke hāpai. E kala ʻia ʻoe mai ka hālāwai ʻana i kēia mau koi inā ʻaʻole ʻoe i menstruated (he wā) no 24 mau mahina i ka lālani, a i ʻole he hysterectomy kāu (ʻoki e wehe i kāu kōpū).

Pono ʻoe e hoʻohana i ʻelua mau ʻano ʻoluʻolu o ka kaohi hānau no 4 mau pule ma mua o kou hoʻomaka ʻana e lawe i ka thalidomide, i kou wā e mālama ai, a no 4 mau pule ma hope o kāu lapaʻau ʻana. E haʻi aku kāu kauka iā ʻoe i ke ʻano o ka kaohi hānau e ʻae ʻia. Pono ʻoe e hoʻohana i kēia ʻano ʻelua o ka kaohi hānau i nā manawa āpau ke ʻole ʻoe e hōʻoia ʻaʻole ʻoe e moe kolohe me kahi kāne no 4 mau pule ma mua o kou lapaʻau ʻana, i kāu wā e hoʻomaʻamaʻa ai, a no 4 mau pule ma hope o kāu lapaʻau.

Hiki i kekahi mau lāʻau ke hana i nā mea pale hormonal i mea maikaʻi ʻole. Inā ʻoe e hoʻolālā e hoʻohana i nā contraceptive hormonal (nā lāʻau kaohi hānau, nā pākuʻi, nā implants, nā inikopa, nā apo, a i ʻole nā ​​polokalamu intrauterine) i kou wā e mālama ʻia ai me thalidomide, e haʻi i kāu kauka e pili ana i nā lāʻau a pau, nā wikamina, a me nā mea hoʻowalewale lāʻau āu e lawe nei a hoʻolālā paha e lawe . E ʻōlelo pono: griseofulvin (Grifulvin); kekahi mau lāʻau e mālama ai i ka maʻi pale maʻi (HIV) e like me amprenavir (Agenerase), atazanavir (Reyataz), darunavir (Prezista), fosamprenavir (Lexiva), indinavir (Crixivan), lopinavir (i Kaletra), nelfinavir (Viracept), ritonavir (Norvir , ma Kaletra), saquinavir (Invirase), a me tipranavir (Aptivus); kekahi mau lāʻau no ka hopu ʻana e like me ka carbamazepine (Carbatrol, Equetro, Tegretol) a me phenytoin (Dilantin, Phenytek); modafinil (Provigil); penikila; rifampin (Rimactane, Rifadin); rifabutin (Mycobutin); a me kā John John wort. He nui nā lāʻau ʻē aʻe e hoʻopilikia paha i ka hana o nā kaola pale hormonal, no laila e ʻike pono i kāu kauka i nā lāʻau āpau āu e lawe nei a hoʻolālā paha e lawe, ʻo ia hoʻi nā mea i hōʻike ʻole ʻia ma kēia papa inoa.

Pono ʻoe i ʻelua mau hoʻokolohua maikaʻi ʻole o ka hāpai ma mua o ka hiki iā ʻoe ke hoʻomaka e lawe i ka thalidomide. Pono ʻoe e hoʻāʻo ʻia no ka hāpai ʻana i loko o kahi keʻena hoʻokolohua i kekahi mau manawa i kāu mālama ʻana. E haʻi aku kāu kauka iā ʻoe i ka manawa a me kahi e loaʻa ai kēia mau hoʻokolohua.

E hoʻōki i ka lawe ʻana i ka thalidomide a kāhea koke aku i kāu kauka inā manaʻo ʻoe he hāpai ʻoe, lohi ʻoe, kūlike ʻole, a i hala ʻole paha i kahi manawa menstrual, ua loli ʻoe i kou kahe ʻana o ka menstrual, a i ʻole he moe kolohe ʻoe me ka hoʻohana ʻole ʻana i ʻelua ʻano o ka kaohi hānau. I kekahi mau hihia, hiki i kāu kauka ke kuhikuhi i ka contraceptive pilikia ('ke kakahiaka ma hope o ka pila') e pale aku ai i ka hāpai keiki. Inā hāpai ʻoe i kāu wā e lapaʻau ai, koi ʻia kāu kauka e kāhea iā FDA a me ka mea hana. E ʻike pono kāu kauka e kamaʻilio pū ʻoe me ke kauka i loea i nā pilikia i ka wā hāpai e hiki ke kōkua iā ʻoe e hana i nā koho kūpono loa iā ʻoe a me kāu pēpē.

No nā kāne e lawe nei i ka thalidomide:

Aia ʻo Thalidomide i ka semen (ka wai i loaʻa ka sperm i hoʻokuʻu ʻia ma o ka peni i ka wā o ka orgasm). Pono ʻoe e hoʻohana i ka latex a i ʻole syntom synthetic a i ʻole e hōʻalo loa i ka pili moekolohe me kahi wahine hāpai a hāpai paha i ka wā e lawe ana ʻoe i kēia lāʻau a no 4 mau pule ma hope o kāu lapaʻau. Koi ʻia kēia inā loaʻa iā ʻoe kahi vasectomy (ʻoki kino e pale ai i ka sperm mai ka haʻalele ʻana i kou kino a hāpai i ka hāpai ʻana). E haʻi koke i kāu kauka inā ua moe kolohe ʻole ʻoe me kahi wahine i hiki ke hāpai a i ʻole manaʻo ʻoe no kekahi kumu ua hāpai kāu hoa.

Mai hāʻawi i ka semen a i ka sperm ʻoiai ʻoe e lawe nei i ka thalidomide a no 4 mau pule ma hope o kāu lapaʻau ʻana.

Pilikia o ke koko clots:

Inā ʻoe e lawe nei i ka thalidomide e mālama ai i ka myeloma he nui (kahi ʻano maʻi ʻaʻai o ka iwi iwi), aia kahi pilikia e hoʻomohala ʻoe i kahi ʻōpū o ke koko i kou mau lima, nā wāwae a me nā akemāmā. ʻOi aku ka nui o kēia pilikia ke hoʻohana ʻia ka thalidomide me nā lāʻau chemotherapy e like me dexamethasone. Kāhea koke i kāu kauka inā ʻike ʻoe i kekahi o nā ʻōuli penei: ʻeha, palupalu, ʻulaʻula, hoʻomehana, a i ʻole ka pehu ʻana i nā lima a me nā wāwae; pokole o ka hanu; a ʻehaʻeha paha. Hiki paha i kāu kauka ke kuhikuhi i kahi anticoagulant ('blood thinner') a i ʻole aspirin e kōkua i ka hōʻoki ʻana i nā clots mai ka hana ʻana i ka wā o kāu mālama ʻana me thalidomide.

E kamaʻilio me kāu kauka e pili ana i nā pilikia o ka lawe ʻana i thalidomide.

Hoʻohana ʻia ʻo Thalidomide me ka dexamethasone e mālama ai i nā myeloma he nui i ka poʻe i loaʻa koke i kēia maʻi. Hoʻohana wale ʻia a i ʻole me nā lāʻau ʻē aʻe e mālama a pale i nā ʻōuli o ka erythema nodosum leprosum (ENL; nā ʻāpana o nā ʻeha ʻeha, ke kuni, a me nā ʻino nerve i kū i ka poʻe me ka maʻi ʻo Hansen [leprosy]). Aia ʻo Thalidomide i loko o ka papa o nā lāʻau i kapa ʻia he mau mea pale maʻi. Mālama ia i nā myeloma he nui e ka hoʻoikaika ʻana i ka ʻōnaehana pale e hakakā i nā hunaola maʻi ʻaʻai. Mālama ia iā ENL ma ka ālai ʻana i ka hana o kekahi mau mea kūlohelohe i kumu i ka pehu.

Hele mai ʻo Thalidomide ma ke ʻano he capsule e lawe ma ka waha. Lawe pinepine ʻia ʻo Thalidomide me ka wai i hoʻokahi manawa i ka lā i ka manawa hiamoe a ma kahi o 1 mau hola ma hope o ka ʻaina ahiahi. Inā ʻoe e lawe nei i ka thalidomide e mālama iā ENL, hiki i kāu kauka ke ʻōlelo iā ʻoe e lawe ʻoi aku ma mua o hoʻokahi manawa i ka lā, ma ka liʻiliʻi he 1 hola ma hope o ka ʻai. Lawe i ka thalidomide ma kahi o ka manawa like (s) i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pololei i ka thalidomide e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E mālama i nā capsule i kā lākou pahu a hiki i kou mākaukau e lawe iā lākou. Mai wehe i nā capsule a lawelawe iā lākou ma mua o ka pono. Inā pili kou ʻili me nā capsule naha a i ʻole ka pauka, holoi i kahi i hōʻike ʻia me ke kopa a me ka wai.

ʻO ka lōʻihi o kāu lapaʻau e pili ana i ka pane ʻana o kāu mau ʻōuli i ka thalidomide a inā hoʻi e hoʻi mai kāu mau hōʻailona ke kū ʻoe i ka lawe ʻana i ka lāʻau. Pono paha kāu kauka e hoʻopau i kāu lāʻau a hōʻemi paha i kāu lāʻau inā ʻike ʻoe i kekahi mau hopena ʻaoʻao. Mai hōʻoki i ka lawe ʻana i ka thalidomide me ke kamaʻilio ʻole ʻana me kāu kauka. Ke pau kāu lapaʻau ʻana e hoʻoliʻiliʻi paha kāu kauka.

Hoʻohana ʻia ʻo Thalidomide i kekahi manawa e mālama i kekahi ʻano ʻili e pili ana i ka pehu a me ka ukiuki. Hoʻohana ʻia ia e mālama i kekahi mau pilikia o ka maʻi pale maʻi (HIV) e like me ka aphthous stomatitis (ke ʻano e hana ʻia ai nā puʻupuʻu ma ka waha), ka maʻi diarrhea e pili ana i ka maʻi HIV, ka maʻi hōʻino e pili ana i ka maʻi HIV, kekahi mau maʻi, a me ka sarcoma a Kaposi (kahi ʻano o ka maʻi ʻaʻai ʻili). Ua hoʻohana ʻia ʻo Thalidomide e mālama i kekahi ʻano o ka maʻi ʻaʻai a me nā tumors, ka pohō kaumaha o nā mea maʻi me nā ʻōnaehana pale nawaliwali, ka hoʻopili mau ʻana me ka maʻi o ka mea hoʻokipa (kahi pilikia e hiki ke hana ma hope o ka hoʻoneʻe ʻana o ka iwi iwi kahi e hoʻouka ai ka mea hou i kanu i ka mea transplant ke kino), a me ka maʻi o Crohn (kahi ʻano e hoʻouka ai ke kino i ka uhi o ka digestive tract, e hōʻeha ai i ka ʻeha, ka palahī, ka pohō kaumaha, a me ke kuni). E kamaʻilio me kāu kauka e pili ana i nā pilikia o ka hoʻohana ʻana i kēia lāʻau no kou maʻi.

Kuhi ʻia kēia lāʻau i kekahi manawa no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i thalidomide,

• e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka thalidomide a i ʻole nā ​​lāʻau ʻē aʻe.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E kuhikuhi pono i nā lāʻau i helu ʻia i ka ʻARlelo Aʻo IMPORTANT a me kekahi o kēia mau mea: antidepressants; nā barbiturates e like me pentobarbital (Nembutal), phenobarbital, a me secobarbital (Seconal); chlorpromazine; didanosine (Videx); nā lāʻau no ka hopohopo, nā maʻi noʻonoʻo, a i ʻole ka hopu ʻana i ka maʻi; kekahi mau lāʻau chemotherapy no ka maʻi ʻaʻai e like me cisplatin (Platinol), paclitaxel (Abraxane, Taxol), a me vincristine; reserpine (Serpalan); nā mea hoʻonanea; paina moe; a me nā tranquilizers. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa iā ʻoe ka maʻi maʻi maʻi (HIV), loaʻa ka maʻi maʻi maʻi (AIDS), kahi haʻahaʻa haʻahaʻa o nā hunaola keʻokeʻo i loko o kou koko, a i ʻole nā ​​ʻūlū.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū.
• E ʻike ʻoe i ka thalidomide e hiamoe ai ʻoe. Mai hoʻokele i kahi kaʻa, hana i nā mīkini, a hana i nā hana ʻē aʻe e koi iā ʻoe e makaʻala a hiki i kou ʻike ʻana i ka hopena o kēia lāʻau iā ʻoe.
• e noi i kāu kauka e pili ana i ka hoʻohana palekana o nā mea inu ʻona ʻoiai ʻoe e lawe nei i ka thalidomide. Hiki i ka waiʻona ke hana i nā hopena ʻino mai thalidomide i ʻoi aku ka maikaʻi.
• pono ʻoe e ʻike ʻo ka thalidomide ke kumu o ka puʻupuʻu, ka uila, a me ka maʻule ke ala koke ʻoe mai kahi kūlana wahaheʻe. I mea e pale ai i kēia pilikia, e hele mālie i waho o kahi moe, e hoʻomaha ana i kou mau wāwae i ka papahele no kekahi mau minuke ma mua o ke kū ʻana i luna.
• pono ʻoe e ʻike aia ka thalidomide i loko o kou koko a me nā wai o ke kino. ʻO kēlā me kēia mea e launa me kēia wai e komo i nā mīkina lima a i ʻole holoi i nā wahi i hōʻike ʻia o ka ʻili me ke kopa a me ka wai.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā he emi ia ma mua o 12 mau hola a hiki i kāu kau palena hope e hoʻolālā ʻia, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Thalidomide i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• hiamoe
• huikau
• hopohopo
• kaumaha a i ʻole ʻano hoʻololi ke ʻano
• paʻakikī e hiamoe a hiamoe paha
• iwi, nāʻiʻo, ami, a ʻeha hoʻi
• nāwaliwali
• ʻeha poʻo
• loli i ka makemake
• loli ke kaupaona
• nausea
• kōpaʻa
• waha maloo
• ʻili maloʻo
• ʻili mae
• luliluli ʻole ʻana i kahi ʻāpana o ke kino
• ka pehu o nā lima, ka wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo
• ka paʻakikī e hoʻokō a mālama ʻana paha i kahi kūkulu

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• hūwī
• ʻūlili
• hives
• ʻili a ʻili hoʻi i ka ʻili
• pehu o ka maka, ʻāʻī, elelo, lehelehe, a i ʻole nā ​​maka
• hulahula
• pilikia i ka ale ʻana a me ka hanu ʻana
• fiva, ʻeha puʻu, ʻalalā, ʻū, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi
• lohi a wikiwiki paha ka puʻuwai puʻuwai
• ka hopu ʻana

Hoʻokumu paha ʻo Thalidomide i nā hōʻino nerve i hiki ke koʻikoʻi a paʻa mau. Hiki ke hana i kēia hōʻino i kēlā me kēia manawa i ka manawa a ma hope paha o kāu lapaʻau. E nānā pinepine kāu kauka iā ʻoe e ʻike pehea i hopena ai ka thalidomide i kāu ʻōnaehana hopohopo. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e hoʻōki i ka lawe ʻana i ka thalidomide a kāhea koke aku i kāu kauka: numbness, tingling, pain, or burn in the hands and wāwae.

Hoʻokumu paha ʻo Thalidomide i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino iā thalidomide.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Thalomid^®