Mea Kākau: Virginia Floyd
Lā O Ka Hana: 5 Aukake 2021
HōʻAno Hou I Ka Lā: 22 Ianuali 2025
Anonim
Dr. Lawrence Korngut, University of Calgary: Pimozide for the treatment of ALS
Wikiō: Dr. Lawrence Korngut, University of Calgary: Pimozide for the treatment of ALS

Anter

Ua hōʻike ʻia nā noiʻi i nā mākua ʻelemakule me ka dementia (kahi maʻi lolo e pili ana i ka hiki ke hoʻomanaʻo, noʻonoʻo pono, kamaʻilio, a hana i nā hana o kēlā me kēia lā a hiki ke hoʻololi i ka naʻau a me ke ʻano) e lawe i nā antipsychotics (nā lāʻau no ka maʻi noʻonoʻo) e like me pimozide loaʻa ka manawa kūpono o ka make i ka wā o ka lāʻau.

ʻAʻole ʻae ʻia ʻo Pimozide e ka Food and Drug Administration (FDA) no ka mālama ʻana i nā pilikia o ka lawena i nā mākua ʻelemākule me ka dementia. E kamaʻilio me ke kauka nāna i kuhikuhi i kēia lāʻau inā ʻoe, he lālā ʻohana, a i ʻole kekahi mea āu e mālama ai he dementia a ke lawe nei ʻoe i ka pimozide. No ka ʻike hou aku, e kipa i ka pūnaewele FDA: http://www.fda.gov/Drugs

Hoʻohana ʻia ʻo Pimozide e kāohi i ka motika a i ʻole nā ​​ʻōlelo waha (kahi pono e kaohi ʻole e hana hou i kekahi neʻe ʻana a i ʻole nā ​​kani) i hoʻokumu ʻia e ka maʻi o Tourette (ke ʻano i hōʻike ʻia e nā motika a i ʻole nā ​​ʻatikala waha). Hoʻohana wale ʻia ʻo Pimozide e mālama ai i ka poʻe hiki ʻole ke lawe i nā lāʻau ʻē aʻe a i ʻole i lawe i nā lāʻau ʻē aʻe me ka ʻole o nā hopena maikaʻi. Hoʻohana wale ʻia ʻo Pimozide e mālama ai i nā hana ʻino koʻikoʻi e hōʻoki ai i ke kanaka mai ke aʻo ʻana, hana ʻana, a i ʻole ke hana ʻana i nā hana o kēlā me kēia lā.


Aia ʻo Pimozide i loko o ka papa o nā lāʻau i kapa ʻia he antipsychotics maʻamau. Hana ia ma ka hōʻemi ʻana i ka pīhoihoi ʻole i ka lolo.

Hele mai ʻo Pimozide ma ke ʻano he papa e lawe ma ka waha. Lawe ʻia ia i hoʻokahi manawa i ka lā i ka manawa moe a i ʻelua a ʻoi mau manawa i ka lā. E lawe i ka pimozide ma kahi o ka manawa like (s) i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe pono i ka pimozide e like me ke kuhikuhi.Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E hoʻomaka paha kāu kauka iā ʻoe ma kahi haʻahaʻa o ka pimozide a hoʻonui iki i kāu lāʻau, ʻaʻole ʻoi aku i hoʻokahi manawa i kēlā me kēia 2 a 3 mau lā. Hiki i kāu kauka ke hōʻemi i kāu lāʻau i ka manawa e kāohi ʻia kāu ʻano. E haʻi pono i kāu kauka i kou ʻano i kou wā e mālama ai me ka pimozide.

Mālama ʻo Pimozide i ka maʻi o Tourette akā ʻaʻole ia e hoʻōla iā ia. Lōʻihi paha ka manawa ma mua o kou ʻike i ka pono piha o ka pimozide. E hoʻomau i ka lawe ʻana i ka pimozide ʻoiai inā maikaʻi ʻoe. Mai hōʻoki i ka lawe ʻana i ka pimozide me ke kamaʻilio ʻole ʻana me kāu kauka. Inā kū koke ʻoe i ka lawe ʻana i ka pimozide, ʻike paha ʻoe i ka paʻakikī e kaohi i kāu neʻe. E hoʻoliʻiliʻi paha kāu kauka i kāu lāʻau.


Hoʻohana ʻia ʻo Pimozide i kekahi manawa e mālama i ka schizophrenia (kahi maʻi noʻonoʻo e hoʻopilikia ai i kahi noʻonoʻo a ʻano ʻē paha, nalowale o ka hoihoi i ke ola, a me nā ʻano ikaika a kūpono ʻole paha) a me kekahi ʻano, ʻano, neʻe, a me nā maʻi psychiatric i nā mākua E kamaʻilio me kāu kauka e pili ana i nā pilikia e hiki ke hoʻohana i kēia lāʻau no kāu maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e kamaʻilio me kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka pimozide,

  • e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka pimozide, nā lāʻau ʻē aʻe no ka maʻi noʻonoʻo, a i ʻole nā ​​lāʻau ʻē aʻe.
  • e haʻi i kāu kauka inā e lawe nei ʻoe i kekahi o nā lāʻau aʻe: kekahi antibiotics me azithromycin (Zithromax, Z-Pak), clarithromycin (Biaxin), erythromycin (E.E.S., E-Mycin, Erythrocin), a me moxifloxacin (Avelox); nā antifungals e like me itraconazole (Sporanox) a me ketoconazole (Nizoral); trioxide arsenic (Trisenox); dofetilide (Tikosyn); chlorpromazine; dolasetron (Anzemet); droperidol (Inapsine); Nā mea hoʻopalekana protease HIV e like me indinavir (Crixivan), nelfinavir (Viracept), saquinavir (Invirase), a me ritonavir (Norvir, ma Kaletra); nā lāʻau no ke kuʻi puʻuwai ʻole e like me amiodarone (Cordarone), disopyramide (Norpace), procainamide, quinidine, a me sotalol (Betapace); nā lāʻau no ka maʻi noʻonoʻo a me ka nausea; mefloquine (Lariam); nefazadone; pentamidine (Nebu-Pent); ʻo kekahi mau mea hoʻoliʻiliʻi serotonin reuptake (SSRI) e like me citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil, Pexeva), a me sertraline (Zoloft); tacrolimus (Prograf); thioridazine; zileuton (Zyflo); a me ka ziprasidone (Geodon). E haʻi paha kāu kauka iā ʻoe mai lawe i ka pimozide.
  • e haʻi i kāu kauka inā lawe ʻoe i nā lāʻau i hiki ke kumu i nā tics, me nā amphetamine e like me amphetamine (Adderall) a me dextroamphetamine (Dexadrine, Dextrostat); pemoline (Cylert) (ʻaʻole loaʻa ma ka US); a me ka methylphenidate (Concerta, Ritalin). E haʻi paha kāu kauka iā ʻoe e haʻalele i ka lawe ʻana i kāu lāʻau no kekahi manawa ma mua o kou hoʻomaka ʻana i ka lawe ʻana i ka pimozide. E hōʻike kēia i kāu kauka inā pili kāu mau tics e nā lāʻau ʻē aʻe a hiki ke mālama ʻia e ke kāpae ʻana.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E haʻi pono i kekahi o kēia mau mea: antidepressants; cimetidine (Tagamet); diuretics ('pills wai'); nā lāʻau no ka hopohopo, ʻeha, a me ka hopu ʻana; nā mea hoʻonanea; paina moe; ticlopidine (Ticlid); a me nā tranquilizers. Nui paha nā lāʻau ʻē aʻe e launa pū me ka pimozide, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i helu ʻia ma aneʻi a i ʻole nā ​​papa inoa ma luna. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
  • e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa iā QT Syndrome lōʻihi (ke ʻano e hoʻonui ai i ka makaʻu o ka hoʻomohala ʻana i kahi puʻuwai puʻuwai ʻole e hiki ai ke lilo i ka ʻike a make koke paha); he kuʻi puʻuwai kūpono ʻole; aiʻole nā ​​pae haʻahaʻa o ka potassium a magnesium paha i kou koko. E haʻi pū aku i kāu kauka inā loaʻa ʻoe i ka maʻi nui ma mua o kāu hoʻomaʻamaʻa a i ʻole i kēlā me kēia manawa i kāu wā e lapaʻau ai. E haʻi paha kāu kauka iā ʻoe mai lawe i ka pimozide.
  • e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa i ka maʻi ʻaʻai umauma; Maʻi ʻo Parkinson (PD; kahi maʻi o ka ʻōnaehana hopohopo nāna e hoʻopilikia i ka neʻe ʻana, ka mālama ʻana i nā mākala, a me ke kaulike); glaucoma (ke ʻano e hoʻonui ai ke kaomi o ka maka i hiki ke alakaʻi i ka nalo lohi o ka ʻike); nā pilikia me ka urination; pilikia e mālama i kāu kaulike, kahi electroencephalogram abnormal (EEG; hōʻike e hoʻopaʻa i ka hana uila i ka lolo); ka hopu ʻana; aiʻole ka prostate, ka ate, a me nā maʻi puʻupaʻa. E haʻi aku i kāu kauka inā pono ʻoe e hoʻōki i ka lawe ʻana i kahi lāʻau no ka maʻi noʻonoʻo ma muli o nā hopena ʻino.
  • e haʻi i kāu kauka inā hāpai ʻoe, keu hoʻi inā ʻoe i nā mahina hope o kou hāpai ʻana, a inā ʻoe e hoʻolālā e hāpai a i ʻole e hānai umauma ana. Inā hāpai ʻoe i ka lawe ʻana i ka pimozide, e kāhea i kāu kauka. Hiki paha i ka Pimozide ke hoʻopilikia i nā keiki hānau hou ma hope o ka lawe ʻana inā lawe ʻia i nā mahina hope o ka hāpai ʻana.
  • inā ke ʻoki nei ʻoe, e like me ke ʻoki niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe ana ʻoe i ka pimozide.
  • pono ʻoe e ʻike i ka pimozide e hiamoe ai ʻoe a pili i kou noʻonoʻo a me kāu neʻe ʻana, keu hoʻi i ka hoʻomaka o kāu lapaʻau. Mai hoʻokele i kahi kaʻa a hana i nā mīkini a ʻike ʻoe i ka hopena o kēia lāʻau iā ʻoe.
  • pono ʻoe e ʻike ʻo ka pimozide ke kumu o ka puʻupuʻu, ka uila, a me ka nāwaliwali ke ala koke ʻoe mai kahi kūlana wahaheʻe. I mea e hōʻalo ai i kēia pilikia, e hele mālie i waho o kahi moe, e hoʻomaha ana i kou mau wāwae i ka papahele no kekahi mau minuke ma mua o ke kū ʻana i luna.
  • e nīnau i kāu kauka e pili ana i ka hoʻohana palekana ʻana o ka waiʻona i kou wā e mālama ai me ka pimozide. Hiki i ka waiʻona ke hana i nā hopena ʻino o pimozide i ʻoi aku ka maikaʻi.

Mai ʻai i ka hua waina a i ʻole inu i ka wai huaʻikuʻi ke lawe nei ʻoe i kēia lāʻau.


E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Pimozide i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • nāwaliwali
  • ʻino, hoʻoluhi, a i ʻole pilikia i ka mālama ʻana i kāu kaulike
  • waha maloo
  • hoʻonui kohu
  • pāhoehoe
  • kōpaʻa
  • pololi ʻano ʻē a i ʻole make wai
  • nā hoʻololi i ke kūlana
  • hopohopo
  • nā hoʻololi i ka hana
  • pilikia i ka hoʻāʻo ʻana i ka meaʻai
  • ʻike i ka mālamalama
  • nā hoʻololi i ka hihiʻo
  • hoʻemi i ka moekolohe ma nā kāne
  • helehelena hakahaka
  • hele wāwae
  • ʻano ʻoniʻoni, hoʻolohi, a i ʻole hiki ʻole ke kāohi ʻia o kekahi ʻāpana o ke kino
  • hoʻomaha ʻole
  • pilikia pilikia ʻōlelo
  • nā hoʻololi i ka kākau lima
  • hūwī

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka:

  • fiva
  • ʻoʻoleʻa o ka mākala
  • hāʻule ʻana
  • huikau
  • ka houʻu ʻana
  • wikiwiki a i ʻole kuʻi puʻuwai puʻuwai
  • ʻāʻī ʻāʻī
  • paʻa i ka ʻāʻī
  • pilikia i ka hanu ʻana a i ʻole ke ale ʻana
  • alelo e puka ana i ka waha
  • ʻoni, maikaʻi ke ʻano o ke alelo
  • ke kaohi ʻole, ka helehelena, ka waha, a me ka neʻe ʻana o ka iwi

I nā koina kiʻekiʻe, ua hoʻokumu ka pimozide i nā tumors i nāʻiole. ʻAʻole ia he kumu no ka pimozide e hoʻokumu i nā tumors i nā kānaka. E kamaʻilio me kāu kauka e pili ana i ka makaʻu i ka lawe ʻana i kēia lāʻau.

Hoʻokumu paha ʻo Pimozide i kahi puʻuwai puʻuwai ola ʻole e hoʻoweliweli nei. ʻO kekahi poʻe i lawe i nā koina kiʻekiʻe o ka pimozide e mālama i nā kūlana ʻē aʻe ma mua o Tourette's Syndrome i make koke, no ka ʻano paha o kēia ʻano puʻuwai kūlike ʻole. E kauoha kāu kauka i kahi electrocardiogram (hoʻāʻo e hoʻopaʻa i ka hana uila o ka puʻuwai) ma mua a i kou wā e mālama ai me ka pimozide e ʻike inā loaʻa paha iā ʻoe nā pilikia puʻuwai e hiki ke hoʻonui ʻia e ka pimozide a ʻike inā paha ua hoʻokumu ka pimozide i nā pilikia puʻuwai. E kamaʻilio me kāu kauka e pili ana i ka makaʻu i ka lawe ʻana i kēia lāʻau.

Hoʻokumu paha ʻo Pimozide i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Pākuʻi ʻia paha nā ʻōuli o ka overdose:

  • helehelena hakahaka
  • hele wāwae
  • ʻano ʻoniʻoni, hoʻolohi, a i ʻole hiki ʻole ke kāohi ʻia o kekahi ʻāpana o ke kino
  • hoʻomaha ʻole
  • puʻuwai wikiwiki
  • hiamoe
  • koma (nalo o ka noʻonoʻo no kahi manawa o ka manawa)
  • paʻakikī i ka hanu ʻana

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i ka pimozide.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

  • Orap®
Nānā Hou - 07/15/2017

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