Mea Kākau: Marcus Baldwin
Lā O Ka Hana: 21 Iune 2021
HōʻAno Hou I Ka Lā: 16 Nowemapa 2024
Anonim
Long-Acting Injectable Cabotegravir: the Future of HIV PrEP?
Wikiō: Long-Acting Injectable Cabotegravir: the Future of HIV PrEP?

Anter

Hoʻohana ʻia ʻo Cabotegravir me ka rilpivirine (Edurant) ma ke ʻano he manawa pōkole e mālama ai i ka maʻi maʻi maʻi maʻi maʻi type 1 (HIV-1) i kekahi mau mākua. Hoʻohana ʻia ia e ʻike inā hiki i ke kino ke ʻae i ka cabotegravir ma mua o ka loaʻa ʻana o ka cabotegravir injection a ma kekahi mau hihia o ka nalo ʻana o nā koina cabotegravir. Aia ʻo Cabotegravir i loko o ka papa o nā lāʻau i kapa ʻia ʻo nā mea hoʻopili ʻo HIV integrase. Hana ia ma ka hoʻemi ʻana i ka nui o ka maʻi HIV i loko o ke koko. ʻOiai ʻaʻole hoʻōla ka cabotegravir i ka maʻi HIV, hiki iā ia ke hoʻemi i kou manawa o ka hoʻomohala ʻia ʻana o ka maʻi maʻi maʻi (AIDS) a me nā maʻi e pili ana i ka maʻi HIV e like me nā maʻi nui a i ʻole ka maʻi ʻaʻai. ʻO ka lawe ʻana i kēia mau lāʻau a me ka hoʻomaʻamaʻa ʻana i ka moekolohe ʻoi aku ka maikaʻi a me ka hoʻololi ʻana i ke ʻano ola ʻē aʻe e hōʻemi paha i ka lawe ʻana (hoʻolaha) i ka maʻi HIV i nā poʻe ʻē aʻe.

Hele mai ʻo Cabotegravir ma ke ʻano he papa e lawe ma ka waha. Lawe ʻia ia me rilpivirine i hoʻokahi manawa i kēlā me kēia lā me ka meaʻai. Lawe i ka cabotegravir me rilpivirine ma kahi o ka manawa like i kēlā me kēia lā. Lawe pū ʻia ʻo Cabotegravir me rilpivirine ma kahi o hoʻokahi mahina (no ka liʻiliʻi he 28 mau lā) ma mua o ka hoʻomaka ʻana o ka mālama ʻana me nā ʻano hana hoʻoheheʻe lōʻihi o kēia mau lāʻau a i ʻole 2 mau mahina inā e nalo ana ka papa hana hoʻoweliweli ma mua o 7 lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe i ka cabotegravir e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.


E hoʻomau i ka lawe ʻana i ka cabotegravir ʻoiai inā maikaʻi ʻoe. Mai hoʻōki i ka lawe ʻana i ka cabotegravir a i ʻole kāu lāʻau anti-HIV ʻē aʻe me ke kamaʻilio ʻole ʻana me kāu kauka. Inā kū ʻoe i ka lawe ʻana i ka cabotegravir a i ʻole lele i nā lāʻau, e ʻinoʻino paha kou kūlana a lilo i mea pale i ka lāʻau.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka cabotegravir,

  • e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka cabotegravir, i nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa cabotegravir. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
  • E haʻi i kāu kauka inā lawe ʻoe i ka carbamazepine (Epitol, Equetro, Tegretol), oxcarbazepine (Trileptal), phenobarbital, phenytoin (Dilantin, Phenytek), rifampin (Rifadin, Rimactane, ma Rifamate, i Rifater), a me rifapentine (Priftin). E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka cabotegravir inā ʻoe e lawe i hoʻokahi aʻoi aku paha o kēia mau lāʻau.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
  • inā ʻoe e lawe i nā antacids i loko o ka puna, magnesium, a i ʻole ke alumini (Maalox, Mylanta, Tums, a me nā mea ʻē aʻe), lawe iā lākou i 2 mau hola ma mua a i ʻole 4 mau hola ma hope o ka lawe ʻana i ka cabotegravir.
  • e haʻi i kāu kauka inā loaʻa ʻoe a i ʻole loaʻa paha iā ʻoe ke kaumaha a i ʻole nā ​​maʻi noʻonoʻo ʻē aʻe, a i ʻole nā ​​maʻi ate.
  • e haʻi i kāu kauka inā hāpai ʻoe, hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Inā hāpai ʻoe i ka lawe ʻana i ka cabotegravir, e kāhea i kāu kauka. ʻAʻole pono ʻoe e hānai i ka hānai inā loaʻa ʻoe i ka maʻi HIV a inā ʻoe e lawe ana i ka cabotegravir.
  • pono ʻoe e ʻike he hiki i ka cabotegravir ke hoʻololi i kāu mau manaʻo, hana, a i ʻole ke olakino noʻonoʻo. Kāhea koke i kāu kauka inā hoʻomohala ʻoe i kekahi o nā ʻōuli ma hope ke lawe nei ʻoe i ka cabotegravir: kahi kaumaha hou a i ʻole ke kaumaha paha, a i ʻole ka noʻonoʻo ʻana e pepehi iā ʻoe iho a hoʻolālā paha a hoʻāʻo paha e hana pēlā. E ʻike pono i kou ʻohana i nā hōʻailona e koʻikoʻi paha i hiki iā lākou ke kāhea i kāu kauka inā ʻaʻole hiki iā ʻoe ke ʻimi i ka lāʻau iā ʻoe iho.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.


E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai, me kahi pāʻina. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hiki i ka Cabotegravir ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • ʻeha poʻo
  • nausea
  • moeʻuhane ʻino
  • hopohopo
  • paʻakikī e hiamoe a hiamoe paha

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻĀLU WAIWAI SPECIAL, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

  • hū me ka ʻole paha: fever; luhi loa; ʻeha a ʻeha pū paha. pāhaʻa; ʻeha ka waha; pehu o nā maka, lehelehe, alelo, a waha paha; a i ʻole paʻakikī i ka hanu ʻana
  • melemele nā ​​maka a i ʻole ka ʻili; ʻeha o ka ʻōpū ma luna pono; ʻāpala; kahe ana ke koko; lilo o ka makemake ʻole; huikau; mimi melemele a ʻeleʻele paha; a i ʻole nā ​​pā lau

Hoʻokumu paha ʻo Cabotegravir i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.


Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i ka cabotegravir.

E mālama i kahi lako o cabotegravir ma ka lima. Mai kali a hiki i ka pau ʻana o kāu lāʻau e hoʻopiha hou i kāu kuhikuhi.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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Nānā Hou - 03/15/2021

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