ʻO Fenfluramine

Anter

• Ma mua o ka lawe ʻana i ka fenfluramine,
• Hiki i ka Fenfluramine ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i nā ʻARlelo AOAO IMĀKAHI a i ʻole nā ​​WAIKAHI HOU, e hoʻōki i ka lawe ʻana i ka fenfluramine a kāhea koke aku i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.
• Pākuʻi ʻia paha nā ʻōuli o ka overdose:

Hoʻokumu paha ʻo Fenfluramine i nā pilikia nui o ka puʻuwai a me ka hanu. E haʻi i kāu kauka inā loaʻa paha iā ʻoe ka maʻi puʻuwai a i ʻole puʻupuʻu. E hana kāu kauka i kahi echocardiogram (hōʻike e hoʻohana i nā nalu kani e ana i ka hiki i kou puʻuwai ke pauma i ke koko) ma mua o kou hoʻomaka ʻana i ka fenfluramine, i kēlā me kēia 6 mahina i ka wā o ka mālama ʻana, a hoʻokahi manawa 3 a 6 mau mahina ma hope o kāu hopena hope loa o fenfluramine.Kāhea koke aku i kāu kauka inā loaʻa iā ʻoe kekahi o kēia mau ʻōuli a me nā ʻōuli i ka wā o ka mālama ʻana: ka pōkole o ka hanu, ka ʻeha o ka umauma, ka luhi a me ka nāwaliwali paha, ka wikiwiki a me ke kuʻi ʻana o ka puʻuwai puʻuwai me ka hoʻonui ʻana i ka hana, hoʻomālamalama, maʻule, pulse kūpono ʻole, kuʻekuʻe wāwae a wāwae paha, a i ʻole. ke kala bluish i nā lehelehe a me ka ʻili.

Ma muli o nā pilikia me kēia lāʻau, loaʻa wale ka fenfluramine ma o kahi papahana hoʻokaʻawale palena kūikawā. ʻO kahi papahana i kapa ʻia ʻo Fintepla Risk Evaluation and Mitigation Strategies (REMS) polokalamu. Pono ʻoe, kāu kauka, a me kāu kauka lāʻau e kau inoa i ka papahana Fintepla REMS ma mua o ka loaʻa ʻana iā ia.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua e nānā i ka pane o kou kino i ka fenfluramine.

E hāʻawi aku kāu kauka a mea kauka paha iā ʻoe i ka palapala ʻike hoʻomanawanui o ka mea hana (Kauka Lapaʻau) ke hoʻomaka ʻoe i ka lāʻau me fenfluramine a i kēlā me kēia manawa e hoʻopiha hou i kāu kauka. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.

Hoʻohana ʻia ʻo Fenfluramine e kaohi i ka hopu ʻana i nā keiki mai nā makahiki 2 a ʻoi aku me ka maʻi Dravet (kahi maʻi i hoʻomaka i ka wā kamaliʻi a kumu i ka hopu ʻana a ma hope e alakaʻi i nā lohi ulu a me nā loli i ka ʻai, kaulike, a me ka hele wāwae). Aia ʻo Fenfluramine i kahi papa o nā lāʻau i kapa ʻia anticonvulsants. ʻAʻole maopopo ʻia pehea e hana ai ka fenfluramine, akā hoʻonui ia i ka nui o nā mea kūlohelohe i ka lolo e hōʻemi ai i ka hana hopu.

Hele mai ʻo Fenfluramine ma ke ʻano he hopena (wai) e lawe ma ka waha. Lawe ʻia ia i ʻelua mau manawa i ka lā me ka ʻai ʻole. Lawe i ka fenfluramine ma nā manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pono i ka fenfluramine e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E hoʻomaka paha kāu kauka iā ʻoe ma kahi haʻahaʻa o fenfluramine a hoʻonui iki i kāu lāʻau, ʻaʻole ʻoi aku i hoʻokahi manawa i kēlā me kēia pule.

E hoʻohana i ka syringe waha i hiki mai me nā lāʻau no ke ana ʻana i ka hopena. Mai hoʻohana i ka puna o ka home e ana i kāu mahele. ʻAʻole pololei nā ana ʻana o ka home no ka ana ʻana i nā teaspoon, a loaʻa paha iā ʻoe ka nui o ka lāʻau a i ʻole ʻaʻole lawa ka lāʻau inā ʻoe e ana i kāu lāʻau me kahi teaspoon o ka home E holoi i ka syringe waha me ka wai puna maʻemaʻe a ʻae iā ia e maloʻo ma hope o kēlā me kēia hoʻohana. E hoʻohana i kahi syringe waha maloʻo i kēlā me kēia manawa ke lawe ʻoe i ka lāʻau.

Inā loaʻa iā ʻoe kahi nasogastric (NG) a i ʻole gastric Tube, e wehewehe kāu kauka a kauka paha pehea e hoʻomākaukau ai i ka fenfluramine e lawelawe iā ia.

Kōkua ʻo Fenfluramine e kaohi i ka hopu ʻana, akā ʻaʻole ia e hoʻōla iā lākou. E hoʻomau i ka lawe ʻana i ka fenfluramine ʻoiai inā maikaʻi ʻoe. Mai hōʻoki i ka lawe ʻana i ka fenfluramine me ka walaʻau ʻole ʻana me kāu kauka. Inā kū koke ʻoe i ka lawe ʻana i ka fenfluramine, ʻike paha ʻoe i ka haʻalele ʻana i nā ʻōuli e like me ka hopu ʻana hou a i ʻole worsening seizures. E hoʻoliʻiliʻi paha kāu kauka i kāu lāʻau.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka fenfluramine,

• e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka fenfluramine, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i loko o ka hopena haʻi waha ʻo fenfluramine. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka inā e lawe ana ʻoe a loaʻa paha i nā lāʻau aʻe a i ʻole ua oki paha i ka lawe ʻana iā lākou i nā lā he 14 i hala aku nei: monoamine oxidase (MAO) mea hoʻopili me isocarboxazid (Marplan), linezolid (Zyvox), methylene blue, phenelzine (Nardil), selegiline ʻO Eldepryl, Emsam, Zelapar), a me tranylcypromine (Parnate). Inā kū ʻoe i ka lawe ʻana i ka fenfluramine, pono ʻoe ke kali ma ka liʻiliʻi he 14 mau lā ma mua o kou hoʻomaka ʻana e lawe i kahi mea hoʻopuka MAO.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E haʻi pono i kekahi o kēia mau mea: antidepressants e like me bupropion (Aplenzin, Wellbutrin); nā lāʻau no ka hopohopo; cyproheptadine; dextromethorphan (ʻike ʻia i loko o nā lāʻau lapaʻau he nui; ma Nuedexta); efavirenz (Sustiva); lithium (Lithobid); nā lāʻau no ka maʻi noʻonoʻo; nā lāʻau no ka maʻi migraine e like me almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex), a me zolmitriptan (Zomig); omeprazole (Prilosec); rifampin (Rifadin, Rimactane, ma Rifamate, ma Rifater); nā mea hoʻonanea; nā lāʻau lapaʻau no ka hopu ʻana e like me ka carbamazepine (Carbatrol, Equetro, Tegretol, Teril), clobazam (Onfi, Sympazan), phenobarbital, phenytoin (Dilantin, Phenytek), a me stimipentol (Diamcomit); nā mea kūpale serotonin-reuptake e like me fluoxetine (Prozac, Sarafem, Selfemra), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), a me sertraline (Zoloft); serotonin – norepinephrine reuptake inhibitors (SNRI) e like me desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), levomilnacipran (Fetzima), milnacipran (Savella), a me venlafaxine (Effexor); paina moe; mea hoʻomaluhia; trazodone; a me nā antidepressants tricyclic ('nā hoʻokiʻekiʻe kiʻekiʻe') e like me desipramine (Norpramin) a i ʻole protriptyline (Vivactil). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Hiki paha i nā lāʻau ʻē aʻe ke launa pū me fenfluramine, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka i nā huahana mea kanu a me nā mea hoʻopihaʻaiʻai āu e lawe nei, ʻo ka wort a me ka tryptophan ʻo St.
• e haʻi i kāu kauka inā loaʻa paha iā ʻoe ka glaucoma (hoʻonui i ke kaomi i ka maka e hiki ai ke lilo ka hihi) a i ʻole ke kiʻekiʻe o ke koko. Eia kekahi, e haʻi i kāu kauka inā loaʻa ʻoe a i ʻole loaʻa paha iā ʻoe ke kaumaha, nā pilikia o ka naʻau, nā manaʻo suicidal a i ʻole ka lawena a i ʻole ka maʻi puʻuwai a me ka ate.
• E haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Inā hāpai ʻoe i ka lawe ʻana i ka fenfluramine, e kāhea i kāu kauka.
• pono ʻoe e ʻike i ka fenfluramine e hiamoe ai ʻoe a e paʻakikī iā ʻoe e hana i nā hana e koi ai i ka makaʻala a i ʻole ka hoʻohui kino ʻana. Mai hoʻokele i kahi kaʻa a hana i nā mīkini a ʻike ʻoe i ka hopena o kēia lāʻau iā ʻoe.
• e nīnau i kāu kauka e pili ana i ka hoʻohana palekana ʻana o nā mea inu ʻona a me nā lāʻau i loaʻa ka wai ʻona (kahe a me nā huahana anu, e like me Nyquil, a me nā huahana wai ʻē aʻe) ke lawe nei ʻoe i ka fenfluramine. Hiki i ka waiʻona ke hoʻohui i ka hiamoe i hoʻokumu ʻia e kēia lāʻau.
• pono ʻoe e ʻike e loli paha kou olakino noʻonoʻo i nā ala i manaʻo ʻole ʻia a lilo ʻoe i suicidal (e noʻonoʻo e pili ana i ka hōʻeha a pepehi paha iā ʻoe iho a i ʻole ke hoʻolālā ʻana a hoʻāʻo paha e hana pēlā) ʻoiai ʻoe e lawe nei i ka fenfluramine. ʻO kahi liʻiliʻi o nā mākua a me nā keiki he 5 mau makahiki a ʻoi paha (ma kahi o 1 a 500 mau kānaka) i lawe i nā anticonvulsants, e like me fenfluramine, e mālama i nā ʻano like ʻole i ka manawa o nā noiʻi maʻi ʻana i lilo i suicidal i kā lākou mālama ʻia. ʻO kekahi o kēia poʻe i hoʻomohala i nā manaʻo suicidal a me ka lawena ma mua o hoʻokahi pule ma hope o ka hoʻomaka ʻana e lawe i ka lāʻau. E hoʻoholo ʻoe a me kāu kauka inā ʻoi aku ka nui o nā makaʻi o ka lawe ʻana i kahi lāʻau anticonvulsant ma mua o nā makaʻu o ka lawe ʻole ʻana i ka lāʻau. ʻO ʻoe, kou ʻohana, a i ʻole kāu mea mālama e kāhea koke aku i kāu kauka inā ʻike ʻoe i kekahi o kēia mau ʻōuli: weliweli weliweli; hoʻonāukiuki a hoʻomaha ʻole paha; hoʻonāukiuki hou a i ʻole ke kaumaha paha; hana ana i nā manaʻo hoʻoweliweli; paʻakikī e hiamoe a hiamoe paha; hana hoʻomāinoino, huhū, a kolohe paha; mania (pīhoihoi, ʻano hauʻoli ʻole); ke noʻonoʻo nei e pili ana i ka hōʻino a pepehi paha iā ʻoe iho, a i ʻole ke hoʻolālā ʻana a hoʻāʻo ʻana paha e hana pēlā; a i ʻole nā ​​hoʻololi ʻē aʻe i ke ʻano a me ke ʻano. E ʻike pono i kou ʻohana a mea mālama paha e ʻike i nā hōʻailona e koʻikoʻi paha i hiki iā lākou ke kāhea i ke kauka inā ʻaʻole hiki iā ʻoe ke ʻimi iā ʻoe lāʻau ponoʻī.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hiki i ka Fenfluramine ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• pāhoehoe
• kōpaʻa
• ka luaʻi
• kūmau ʻole a i ʻole nā ​​pilikia me ka hele wāwae
• halo wai ʻana a i ʻole kohu kohu
• paʻakikī e hiamoe a hiamoe paha
• hāʻule
• fiva, uha, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i nā ʻARlelo AOAO IMĀKAHI a i ʻole nā ​​WAIKAHI HOU, e hoʻōki i ka lawe ʻana i ka fenfluramine a kāhea koke aku i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• ka hoʻonāukiuki, nā haʻalulu, ke kuni, ka hou ʻana, ka huikau, ka puʻuwai wikiwiki, ka haʻalulu, ka ʻāʻī a i ʻole ka mimiki ʻana, ka nalowale ʻana o ke kuʻikahi, nausea, ka luaʻi, a i ʻole ka diarrhea
• hoʻololi i ka hihi a ʻike paha i nā loli, e like me ke ʻike ʻana i ka ʻalalā (ʻōkuhi blurr a puni nā mea) a i ʻole nā ​​kiko kala

Hiki i ka Fenfluramine ke hōʻemi i ka makemake ʻole a me ka pohō kaumaha. Inā ʻoe e ʻike i kāu keiki e lilo ana ka paona, e kāhea i kāu kauka. E nānā pono kāu kauka i ka ulu a me ke kaumaha o kāu keiki. E kamaʻilio me kāu kauka inā he hopohopo kāu e pili ana i ka ulu ʻana o kāu keiki a i ʻole ke kaumaha ʻoiai ʻo ia e lawe nei i kēia lāʻau.

Hiki i ka Fenfluramine ke hana i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama i ka hopena waha ma ka mahana wela a mamao aku i ka wela a me ka makū (ʻaʻole i loko o ka lua. Mai hoʻomaʻalili a paʻa ʻole i ka hopena. E hoʻolei i nā haʻina waha i hoʻohana ʻole ʻia i koe he 3 mau mahina ma hope o ka wehe mua ʻana o ka ʻōmole a i ʻole ma hope o ka lā "hoʻolei ʻia ma hope" ma ka lepili, ʻo kēlā lā kēia lā e kokoke ana.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Pākuʻi ʻia paha nā ʻōuli o ka overdose:

• dilated pupils
• arching hope
• wikiwiki a i ʻole kuʻi puʻuwai puʻuwai
• ʻōhinu
• hoʻomaha ʻole
• hopohopo
• haʻalulu
• ka hopu ʻana
• koma (nalo o ka noʻonoʻo no kahi manawa o ka manawa)
• ka hoʻonāukiuki, nā haʻalulu, ke kuni, ka hou ʻana, ka huikau, ka puʻuwai puʻuwai wikiwiki, ka haʻalulu, ka ʻāʻī a i ʻole ka mimiki ʻana, ka nalowale ʻana o ke kuʻikahi, nausea, ka luaʻi, a i ʻole ka palahī

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. ʻO Fenfluramine kahi lāʻau i kāohi ʻia. Hiki ke hoʻopiha hou ʻia nā kuhikuhi ma nā helu kau palena wale nō; e noi i kāu kauka lāʻau inā he nīnau kāu.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Fintepla^®