Pemigatinib

Anter

• Ma mua o ka lawe ʻana i pemigatinib,
• Hoʻokumu paha ʻo Pemigatinib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

Hoʻohana ʻia ʻo Pemigatinib i nā mākua i loaʻa mua i ka lāʻau ma mua e mālama i kekahi ʻano o cholangiocarcinoma (maʻi ʻaʻai bile duct) i pālahalaha ʻia i nā mea kokoke a i ʻole nā ​​ʻāpana ʻē aʻe o ke kino a ʻaʻole hiki ke hemo e ke ʻoki. Aia ʻo Pemigatinib i kahi papa o nā lāʻau i kapa ʻia nā kinase inhibitors. Hana ia ma ke kāpae ʻana i ka hana o ka protein pono ʻole e hōʻailona ai i nā hunaola maʻi ʻaʻai e hoʻonui. Kōkua kēia i ka hōʻoki a hoʻolohi paha i ka hoʻolaha ʻana o nā hunaola maʻi ʻaʻai.

Hele mai ʻo Pemigatinib ma ke ʻano he papa e lawe ma ka waha. Lawe pinepine ʻia me a me ka ʻole o ka meaʻai i kēlā me kēia lā no nā lā 14 mua o kahi pōʻaiapuni 21 mau lā. E hana hou ʻia ke kalapona e like me ka ʻōlelo a kāu kauka. E lawe i ka pemigatinib ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe i pemigatinib e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā papa holoʻokoʻa; mai hoʻokaʻawale, a nau aku, a hoka ʻole iā lākou.

Inā ʻoe e luaʻi ma hope o ka lawe ʻana i pemigatinib, mai lawe i kahi lāʻau ʻē aʻe. E hoʻomau i kāu papa hana maʻamau.

Hiki i kāu kauka ke hōʻemi i kāu lāʻau a i ʻole manawa kūmau a paʻa mau paha i kāu lāʻau inā ʻike ʻoe i kekahi mau hopena ʻaoʻao. Aia kēia i ka maikaʻi o ka hana ʻana o ka lāʻau iā ʻoe a me nā hopena ʻē aʻe āu e ʻike ai. E pono e haʻi i kāu kauka i kou ʻano i kou wā e mālama ai me ka pemigatinib.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i pemigatinib,

• e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka pemigatinib, i nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i loko o ka papa pemigatinib. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E haʻi pono i kekahi o kēia mau mea: antifungals e like me fluconazole (Diflucan), itraconazole (Onmel, Sporanox), ketoconazole (Nizoral), a me voriconazole (Vfend); carbamazepine (Epitol, Tegretol, Teril, nā mea ʻē aʻe); clarithromycin (Biaxin); erythromycin (E.E.S., Erythrocin, nā mea ʻē aʻe); kekahi mau lāʻau e mālama ai i ka maʻi pale maʻi (HIV) e like me efavirenz (Sustiva, i Atripla), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, i kekahi), a i ʻole saquinavir (Invirase); nefazodone; phenobarbital; phenytoin (Dilantin, Phenytek); pioglitazone (Actos); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, ma Rifamate); and verapamil (Calan, Verelan, kekahi). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Hiki paha i nā lāʻau ʻē aʻe ke launa pū me pemigatinib, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St.
• e haʻi i kāu kauka inā pilikia ʻoe i ka ale ʻana i nā papa a i ʻole inā he ʻiʻo a i ʻole he maʻi ʻeha paha kāu.
• E haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a inā ʻoe e hoʻolālā i ka hānau keiki ʻana. Inā he wahine ʻoe, pono ʻoe e lawe i kahi hōʻike hāpai keiki ma mua o kou hoʻomaka ʻana i ka lāʻau lapaʻau a hoʻohana i ka kaohi hānau e pale ai i ka hāpai ʻana i ka wā o kāu lapaʻau a no ka liʻiliʻi he 1 pule ma hope o kāu hopena hope loa Inā he kāne ʻoe, pono ʻoe a me kāu pakanā e hoʻohana i ka kaohi hānau ma kāu wā e mālama ai a no 1 mau pule ma hope o kāu hopena hope loa. E kamaʻilio me kāu kauka e pili ana i nā ʻano hana hānau hiki iā ʻoe ke hoʻohana i kāu wā o kāu mālama ʻana. Inā hāpai ʻoe a ʻo kāu hoa paha i ka lawe ʻana i pemigatinib, e kāhea koke i kāu kauka. Hoʻopilikia paha ʻo Pemigatinib i ka fetus.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. ʻAʻole pono ʻoe e hānai i ka wā e lawe ana ʻoe i pemigatinib a no 1 mau pule ma hope o kāu hopena hope loa.
• pono ʻoe e ʻike ʻo kēia lāʻau i kumu i nā maka maloʻo. E haʻi paha kāu kauka iā ʻoe e hoʻohana i nā waimaka a i ʻole nā ​​lubricant maka kulu i kou wā e mālama ai me ka pemigatinib.

Mai ʻai i ka nui o ka huaʻulu a inu paha i ka wai huaʻikuʻi i ka wā e lawe ana i kēia lāʻau.

Inā ʻoe e nalo i kahi mahele o pemigatinib ma lalo o 4 mau hola, e lawe i ka lāʻau i hala i kou hoʻomanaʻo ʻana iā ia a laila lawe i ka lāʻau aʻe i ka manawa i hoʻopaʻa ʻia. Eia nō naʻe, inā ʻoe e nalo i kahi mahele lāʻau e 4 a ʻoi paha mau hola, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Pemigatinib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• pāhoehoe
• nausea
• hoʻololi i ka ʻono
• ka luaʻi
• nalo ʻai ʻole
• Kaumaha emi
• kōpaʻa
• ʻeha ka ʻōpū
• ʻeha ma nā lehelehe, waha, a ʻāʻī paha
• waha maloʻo a me / a i ʻole ʻili; hoʻemi i ka urination; aiʻole ka puʻuwai wikiwiki
• nā maʻi kui
• poho lauoho
• ʻeha poʻo
• luhi
• ʻeha hui a kua ʻeha paha
• wela a i ʻole urination ʻeha
• ʻeha a pehu paha o nā lima, nā wāwae, nā wāwae a me nā kuʻekuʻe wāwae

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• ʻike maka ʻole, nā floats i ka maka, ke ʻike nei i nā kukuna o ka mālamalama, a i ʻole nā ​​hoʻololi ʻē aʻe i ka hihiʻo
• puʻupuʻu nā mākala, numbness, a i ʻole tingling a puni ka waha

Hoʻokumu paha ʻo Pemigatinib i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help.Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Mālama i nā manawa a pau me kāu kauka, kauka maka, a me ka hale hana. E kauoha kāu kauka i kahi hoʻokolohua lab ma mua o kou hoʻomaka ʻana i kāu lāʻau e ʻike inā hiki ke mālama ʻia i kou maʻi ʻaʻai me pemigatinib. E kauoha nō hoʻi kāu kauka i kekahi mau hoʻokolohua lab a me nā maka ma mua a i kou wā e mālama ai e nānā i ka pane o kou kino i ka pemigatinib.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Pemazyre^®