ʻAkika Bempedoic
Anter
- Ma mua o ka lawe ʻana i ka waikawa bempedoic,
- Hiki i ka Bempedoic acid ke kumu i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
- Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e hōʻoki i ka lawe ʻana i ka waikawa bempedoic a kāhea koke aku i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.
Hoʻohana ʻia ka waikawa Bempedoic me nā loli nohona (kaʻai, ka pohō kaumaha, hoʻoikaika kino) a me kekahi mau lāʻau hoʻohaʻahaʻa kolesterol (HMG-CoA reductase inhibitors [statins]) e hoʻoliʻiliʻi hou i ka lipoprotein (LDL) kolesterol ('maikaʻi kolesterol') i loko o ke koko o nā mākua me ka heterozygous hypercholesterolemia ʻohana (HeFH; kahi ʻano hoʻoilina kahi hiki ʻole ke hemo ʻia ka cholesterol mai ke kino maʻamau a i ʻole ka maʻi puʻuwai. Aia ʻo Bempedoic acid i loko o ka papa o nā lāʻau i kapa ʻia ʻo adenosine triphosphate-citrate lyase (ACL) mea kāohi. Hana ia ma ke kāpae ʻana i ka hana ʻana o ka cholesterol i ke ake.
Hele mai ka Bempedoic acid ma ke ʻano he papa e lawe ma ka waha. Lawe ʻia ia i hoʻokahi manawa i kēlā me kēia lā me ka ʻai ʻole. E lawe i ka waikawa bempedoic ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pono i ka waikawa bempedoic e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.
E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.
Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.
Ma mua o ka lawe ʻana i ka waikawa bempedoic,
- e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka acid bempedoic, i nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i loko o nā papa ʻakika bempedoic. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
- e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E ʻōlelo pono i kekahi o kēia mau mea: fluoroquinolone antibiotics me ciprofloxacin (Cipro), gatifloxacin (Zymar, Zymaxid), levofloxacin (Levaquin), a me ofloxacin; pravastatin (Pravachol); simvastatin (Flolipid, i Vytorin); a i ʻole nā steroid i ʻole oral a i ʻole injectable e like me dexamethasone, methylprednisolone (Medrol), a i ʻole prednisone (Rayos). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
- e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa ka gout, tendon (kahi aʻa fibrous e hoʻopili i kahi iwi i kahi mākala) pilikia, a i ʻole nā maʻi puʻupaʻa a i ʻole ate.
- e haʻi i kāu kauka inā hāpai ʻoe, hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Inā hāpai ʻoe i ka lawe ʻana i ka waika bempedoic, e kāhea i kāu kauka.
Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.
E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.
Hiki i ka Bempedoic acid ke kumu i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
- ʻūpē mākala
- ʻeha kua
- ʻeha ma nā lima a me nā wāwae
Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e hōʻoki i ka lawe ʻana i ka waikawa bempedoic a kāhea koke aku i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.
- ʻeha nui, ʻulaʻula, mehana, palupalu, a huʻi paha o nā hono, keu hoʻi i ka wahi manamana nui
- ka hoʻolohe a i ʻole ke kiʻi ʻana i kahi paʻi a pop paha i kahi tendon; ʻeha ma hope o kahi hōʻeha i kahi tendon; a i ʻole hiki ʻole ke neʻe a lawe i ke kaupaona ma ka ʻāpana tendon i loli
Hiki i ka Bempedoic acid ke kumu i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.
Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).
E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua. Mai wehe i ka desiccant (ʻāpana liʻiliʻi i hoʻopili ʻia me nā papa e omo i ka wai) mai kāu ʻōmole.
He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org
Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.
I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.
E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha aku kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i ka acid bempedoic.
Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.
He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.
- Nexletol®
- Nexlizet® (i loaʻa iā Bempedoic Acid, Ezetimibe)