Upadacitinib

Anter

• Ma mua o ka lawe ʻana i ka upadacitinib,
• Hiki i ka Upadacitinib ke kumu i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

ʻO ka lawe ʻana i ka upadacitinib e hoʻoliʻiliʻi i kou hiki ke hakakā i ka maʻi a hoʻonui i ka makaʻu e loaʻa ʻoe i kahi maʻi koʻikoʻi, e like me ka maʻi fungal, bacterial, a me nā maʻi viral i hoʻolaha ʻia i loko o ke kino. Pono e mālama ʻia kēia mau maʻi i ka haukapila a make paha ka make. E haʻi i kāu kauka inā loaʻa pinepine ʻoe i kekahi ʻano maʻi a i ʻole inā manaʻo ʻoe he ʻano maʻi paha kāu i kēia manawa. Hoʻopili kēia i nā maʻi liʻiliʻi (e like me nā ʻoki hāmama a i ʻole nā ​​ʻeha), nā maʻi i hiki a hele (e like me nā ʻeha anu), a me nā maʻi maʻi ʻole e hele. E haʻi pū aku i kāu kauka inā loaʻa a loaʻa paha ʻoe i ka maʻi diabetes, ka maʻi hoʻomaʻemaʻe kanaka (HIV), loaʻa i ka maʻi maʻi (AIDS), kahi maʻi a me nā ʻano ʻē aʻe e hoʻopili i kāu ʻōnaehana pale Pono ʻoe e haʻi i kāu kauka inā ʻoe e noho a i ʻole i noho ma nā wahi e like me nā awāwa ʻo Ohio a me Misisipi paha kahi e ʻike pinepine ʻia ai nā maʻi fungal. E noi i kāu kauka inā ʻaʻole ʻoe e maopopo inā pili kēia mau maʻi i kou wahi. E haʻi i kāu kauka inā ʻoe e lawe i nā lāʻau e hōʻemi i ka hana o ka ʻōnaehana pale pale e like me kēia: azathioprine (Imuran), cyclosporine (Gengraf, Neoral, Sandimmune), hydroxychloroquine (Plaquenil), leflunomide (Arava), methotrexate (Otrexup, Rasuvo , Trexall); steroid pū me dexamethasone, methylprednisolone (Medrol), prednisolone (Prelone), a me prednisone (Rayos); sulfasalazine; aiʻole tacrolimus (Astagraf, Envarsus XR, Prograf).

E nānā ana kāu kauka iā ʻoe no nā hōʻailona o ka maʻi i ka wā a ma hope o kāu hoʻoponopono ʻana. Inā loaʻa iā ʻoe kekahi o nā ʻōuli aʻe ma mua o kou hoʻomaka ʻana i kāu lāʻau lapaʻau a i ʻole inā ʻike ʻoe i kekahi o nā ʻōuli ma hope a i ʻole ma hope koke paha o kāu lapaʻau ʻana, e kāhea koke i kāu kauka: fever; kāhili; haʻalulu; ʻeha ka ʻili; uā; pokole o ka hanu; Kaumaha emi; mahana, ʻulaʻula, a ʻeha ʻeha paha; ʻeha ma ka ʻili; pinepine, ʻeha, a wela paha ka manaʻo i ka wā o ka urination; diarrhea, a i ʻole ka luhi nui.

Ua hele a maʻi paha ʻoe i ka maʻi palupalu (TB; kahi maʻi puʻuwai koʻikoʻi) akā ʻaʻole i loaʻa nā ʻōuli o ka maʻi. I kēia hihia, ʻo ka lawe ʻana i ka upadacitinib e ʻoi aku ai ke koʻikoʻi i kou maʻi a hoʻomoe iā ʻoe e hoʻomohala i nā ʻōuli. E hana ana kāu kauka i kahi hoʻāʻo ʻili e ʻike inā loaʻa iā ʻoe kahi maʻi TB hemahema ma mua o kou hoʻomaka ʻana i kāu lāʻau me ka upadacitinib. Inā pono, e hāʻawi aku kāu kauka iā ʻoe i ka lāʻau e mālama ai i kēia maʻi ma mua o kou hoʻomaka ʻana e hoʻohana i ka upadacitinib. E haʻi i kāu kauka inā loaʻa paha iā ʻoe ka TB, inā ua noho ʻoe a kipa paha i kahi ʻāina e maʻa mau ai ka TB, a inā ua puni ʻoe i kekahi me ka TB. Inā loaʻa iā ʻoe kekahi o nā ʻōuli o TB, a i ʻole inā hoʻomōhala ʻoe i kekahi o kēia mau ʻōuli i kou wā e lapaʻau ai, e kāhea koke aku i kāu kauka: batukū, ʻūʻē ʻana i nā aʻa koko, ka pohō kaumaha, ka nalowale ʻana o ke kani o nā mākala, a me ke kuni.

Lawe ʻia ka upadacitinib e hoʻonui i ka makaʻu e hoʻomohala ʻoe i kahi lymphoma (maʻi ʻaʻai e hoʻomaka i nā hunaola e hakakā i ka maʻi maʻi) a i ʻole nā ​​ʻano ʻē aʻe e like me ka maʻi ʻaʻai ʻili. E haʻi i kāu kauka inā loaʻa iā ʻoe a ua loaʻa paha iā ʻoe kekahi ʻano maʻi ʻaʻai.

Hiki i ka Upadacitinib ke hoʻonui i ka makaʻu o ke kō a me ka weliweli o ke ola i loko o nā akemāmā a me nā wāwae. Inā ʻoe e ʻike i kekahi o nā hopena aʻe, e kāhea i kāu kauka a i ʻole e kiʻi koke i ka lāʻau lapaʻau pōpilikia: ka ʻeha ʻana i ka ʻeha o ka umauma a i ʻole ka kaumaha o ka umauma. pokole o ka hanu; uā; ʻeha, mehana, ʻulaʻula, pehu, a palupalu wāwae paha; aiʻole ke anuanu i nā lima, nā lima, a i ʻole nā ​​wāwae; a ʻeha ʻeha paha.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. Hiki i kāu kauka ke kauoha i kekahi mau hoʻokolohua lab ma mua, i ka wā, a ma hope o kāu mālama ʻana e nānā i ka pane o kou kino i ka upadacitinib.

E hāʻawi aku kāu kauka a kauka paha iā ʻoe i ka palapala ʻike hoʻomanawanui o ka mea hana (Kauka Lapaʻau) ke hoʻomaka ʻoe i ka lāʻau me upadacitinib a i kēlā me kēia manawa e hoʻopiha hou i kāu kauka. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm a i ʻole ka pūnaewele o ka mea hana e kiʻi i ka Medication Guide.

E kamaʻilio me kāu kauka e pili ana i ka makaʻu (s) o ka lawe ʻana i upadacitinib.

Hoʻohana hoʻokahi ʻia ʻo Upadacitinib a i ʻole me nā lāʻau ʻē aʻe e mālama ai i ka rheumatoid arthritis (ke ʻano e hoʻouka ai ke kino i kāna mau hui ponoʻī e hōʻeha ai i ka ʻeha, ka pehu ʻana, a me ka nalo ʻana o ka hana) i ka poʻe i pane maikaʻi ʻole i ka methotrexate (Otrexup, Rasuvo, Trexall). Aia ʻo Upadacitinib i kahi papa o nā lāʻau i kapa ʻia ʻo Janus kinase (JAK) mea kāohi. Hana ia ma ka hoʻemi ʻana i ka hana o ka ʻōnaehana pale.

Hele mai ʻo Upadacitinib ma ke ʻano he papa hoʻokuʻu lōʻihi (hana lōʻihi). Lawe mau ʻia me ka ʻai ʻole a ʻai ʻole hoʻokahi manawa i kēlā me kēia lā. Lawe i ka upadacitinib ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe iā upadacitinib e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā papa hoʻolōʻihi lōʻihi; mai hoʻokaʻawale, a nau aku, a hoka ʻole iā lākou.

Pono paha kāu kauka e hoʻopau i kahi manawa a kūloko paha i ka lāʻau lapaʻau inā ʻike ʻoe i kekahi hopena ʻino loa. E haʻi pono i kāu kauka i kou ʻano i kou wā e mālama ai.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka upadacitinib,

• e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka upadacitinib, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i loko o nā papa hoʻolōʻihi ʻia upadacitinib. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E kuhikuhi pono i kekahi o kēia mau mea: kekahi mau lāʻau antifungal e like me itraconazole (Onmel, Sporanox) a me ketoconazole; aspirin a me nā lāʻau anti-inflammatory nonsteroidal (NSAIDs) e like me ibuprofen (Advil, Motrin) a me naproxen (Naprosyn, Aleve); nā barbiturates e like me phenobarbital a i ʻole phenytoin (Dilantin, Phenytek); carbamazepine (Carbatrol, Tegretol, Equetro, nā mea ʻē aʻe); clarithromycin (Biaxin, i Prevpac); enzalutamide (Xtandi); kekahi mau lāʻau no ka maʻi HIV me efavirenz (Sustiva), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, ma Kaletra), a me saquinavir (Invirase); nefazodone; rifabutin (Mycobutin); aiʻole rifampin (Rifadin, Rimactane, ma Rifamate, ma Rifater). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Nui paha nā lāʻau ʻē aʻe e launa pū paha me ka upadacitinib, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo keu ʻo St. John's Wort.
• e haʻi i kāu kauka inā loaʻa ʻoe i ka ulcer (ʻeha ma ka lining o kou ʻōpū a i ʻole ʻōpū), divertikulitis (ʻōhū o ka pale o ka ʻōpū nui), herpes zoster (shingles; kahi wīwī e hiki ke hana ʻia i ka poʻe i loaʻa ka moa i ka wā i hala. ), a i ʻole anemia (kahi haʻahaʻa ma mua o ka helu maʻamau o nā hunaola ʻulaʻula), a i ʻole nā ​​maʻi ate, me ka maʻi hepatitis B a i ʻole C.
• e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. Pono ʻoe e loaʻa i kahi hōʻike hāpai ma mua o kou hoʻomaka ʻana i ka lāʻau me upadacitinib. Pono ʻoe e hoʻohana i ka kaohi hānau e pale ai i ka hāpai ʻana i kāu wā mālama a no 4 mau pule ma hope o kāu hopena hope loa. E kamaʻilio me kāu kauka e pili ana i nā ʻano hana hānau hiki iā ʻoe ke hoʻohana. Inā hāpai ʻoe, e kāhea koke i kāu kauka. Hoʻopilikia paha ʻo Upadacitinib i ka fetus.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. ʻAʻole pono ʻoe e hānai i ka wā o kāu mālama ʻana me upadacitinib a no 6 mau lā ma hope o kāu hopena hope loa.
• inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o ka niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe ana ʻoe i ka upadacitinib.
• e haʻi i kāu kauka inā loaʻa iā ʻoe i kēia manawa a i ʻole e hoʻolālā ʻia e loaʻa nā lāʻau āpau. Inā makemake ʻoe i nā lāʻau āpau, pono paha ʻoe e loaʻa nā lāʻau āpau a laila kali ʻoe i kekahi manawa ma mua o ka hoʻomaka ʻana o kāu lāʻau me upadacitinib. ʻAʻohe o nā lāʻau lapaʻau i ka wā o kāu mālama ʻana me ke kamaʻilio ʻole ʻana me kāu kauka.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hiki i ka Upadacitinib ke kumu i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• ihu peʻa a holo paha
• nausea

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• melemele o ka ʻili a i ʻole nā ​​maka, nalo ka makemake ʻole, mimi ʻeleʻele, a i ʻole ka neʻe ʻana o ka ʻōpū me ka pālolo
• pōkole o ka hanu, māluhiluhi, a i ʻole ʻili pale

Hiki i ka Upadacitinib ke hoʻonui i kāu pae kolesterol. E kauoha kāu kauka i nā hoʻokolohua e nānā i kāu pae kolesterol i kāu mālama ʻana me upadacitinib. E kamaʻilio me kāu kauka e pili ana i ka makaʻu i ka lawe ʻana i kēia lāʻau.

Hiki i ka Upadacitinib ke kumu i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i loko o ka pahu hau a i ke ana wela o ka lumi a mamao aku mai ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Rinvoq^®