Polatuzumab vedotin-piiq ka pahu kui

Anter

• Ma mua o ka loaʻa ʻana o ka injection polatuzumab vedotin-piiq,
• ʻO Polatuzumab vedotin-piiq ke kumu o nā hopena. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻaoʻao HOW, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

Hoʻohana ʻia ka hoʻopili ʻana ʻo Polatuzumab vedotin-piiq me bendamustine (Belrapzo, Treanda) a me rituximab (Rituxan) i nā mākua e mālama i kekahi ʻano o ka lymphoma non-Hodgkin (NHL; kahi ʻano maʻi ʻaʻai e hoʻomaka i kahi ʻano o nā keokeo keʻokeʻo e maʻamau. hakakā i ka maʻi maʻi) ʻaʻole hoʻomaikaʻi a hoʻomaikaʻi hou akā hoʻi ʻia ma hope o ka mālama ʻana me ʻelua mau lāʻau chemotherapy ʻē aʻe. Aia ʻo Polatuzumab vedotin-piiq i loko o ka papa o nā lāʻau i kapa ʻia he conjugates antibody-drug. Hana ia ma ka luku ʻana i nā hunaola maʻi ʻaʻai.

Hele mai ʻo Polatuzumab vedotin-piiq ma ke ʻano he pauka e kāwili ʻia me ka wai a hoʻokomo ʻiʻo ʻia (i loko o kahi aa) e ke kauka a kahu wahine paha i kahi wahi olakino. Hāʻawi pinepine ʻia ma luna o 30 a 90 mau minuke i ka lā 1 o kahi pōʻaiapuni 21 lā. E hana hou ʻia ke pōʻaiapuni i 6 mau manawa a i ʻole ka lōʻihi e like me ka ʻōlelo a kāu kauka. Aia ka lōʻihi o kāu mālama ʻana i ka maikaʻi o ka pane ʻana o kou kino i ka lāʻau a me nā hopena ʻaoʻao āu e ʻike ai.

Hiki iā ʻoe ke ʻike i kahi hopena koʻikoʻi a hoʻoweliweli paha i ka wā e loaʻa ai iā ʻoe kahi lāʻau o ka polatuzumab vedotin-piiq injection a i ʻole ma loko o 24 mau hola o ka loaʻa ʻana o kahi lāʻau. E haʻi paha kāu kauka iā ʻoe e lawe i kekahi mau lāʻau i mua o ka loaʻa ʻana o kāu lāʻau e pale ai i kēia mau hopena. E nānā pono kahi kauka a kahu hānai paha iā ʻoe e ʻike pehea ka hopena o kou kino i ka polatuzumab vedotin-piiq. E hoʻomaopopo pono e haʻi aku i kāu kauka i kou ʻano i kou wā e mālama ai me ka inikua polatuzumab vedotin-piiq. Kau kauka paha kau kauka i nā lāʻau ʻē aʻe e kōkua i ka pale ʻana a i ʻole ka hōʻoluʻolu ʻana i kēia mau ʻōuli. Inā ʻoe e ʻike i kekahi o nā ʻōuli ma hope a i ʻole a ma hope o kāu infusion, e haʻi koke i kāu kauka: ka haʻalulu, ka ʻūlū, ka hives, ke kuni, ka pīpī, ka pīpī, paʻakikī i ka hanu ʻana, ka hanu ʻole, a me ke kani ʻana.

Pono paha kāu kauka e hoʻolohi i kāu lāʻau, hoʻoponopono i kāu lāʻau, a i ʻole hoʻokū i kāu lāʻau inā ʻike ʻoe i kekahi mau hopena ʻaoʻao. E pono e haʻi aku i kāu kauka i kou ʻano i kou wā e mālama ai me polatuzumab vedotin-piiq.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka loaʻa ʻana o ka injection polatuzumab vedotin-piiq,

• e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka polatuzumab vedotin-piiq, i nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i ka polatuzumab vedotin-piiq injection. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E haʻi pono i kekahi o kēia mau mea: carbamazepine (Equetro, Tegretol, Teril); clarithromycin (Biaxin, i PrevPac); nā lāʻau e mālama ai iā HIV me efavirenz (Sustiva, i Atripla), indinavir (Crixivan), nevirapine (Viramune), ritonavir (Norvir, ma Kaletra), a me saquinavir (Invirase); itraconazole (Onmel, Sporanox), ketoconazole; nefazodone; phenobarbital, phenytoin (Dilantin, Phenytek); pioglitazone (Actos); rifabutin (Mycobutin); a me rifampin (Rifadin, Rimactane, ma Rifamate). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Pili pū paha nā lāʻau ʻē aʻe he nui me ka polatuzumab vedotin-piiq, no laila e haʻi pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, ʻo nā mea hoʻi i hōʻike ʻole ʻia ma kēia papa inoa.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo keu ʻo St. John's Wort.
• e haʻi i kāu kauka inā loaʻa ʻoe i ka maʻi ʻaʻai a i ʻole loaʻa i ka maʻi ate.
• e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. ʻAʻole pono ʻoe e hoʻomaka i ka loaʻa ʻana o ka injection polatuzumab vedotin-piiq a hiki i ka hōʻike ʻana o kahi hōʻike hāpai keiki ʻaʻole ʻoe hāpai. Inā he wahine ʻoe i hiki ke hāpai, pono ʻoe e hoʻohana i ka kaohi hānau kūpono i kou wā e mālama ai a no 3 mau mahina ma hope o kāu hopena hope loa. Inā he kāne ʻoe me kāu hoa wahine i hiki ke hāpai, pono ʻoe e hoʻohana i ka kaohi hānau pono i kou wā e mālama ai a no 5 mau mahina ma hope o kāu hopena hope loa. E kamaʻilio me kāu kauka e pili ana i nā ʻano hana o ka kaohi hānau e holo pono nāu. Inā hāpai ʻoe a ʻo kāu hoa paha i ka loaʻa ʻana o ka inikuma polatuzumab vedotin-piiq, e kāhea i kāu kauka. Hiki i ka polatuzumab vedotin-piiq injection ke hōʻeha i ka fetus.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. Mai hānai i ka waiū i kou wā e mālama ai a no 2 mau mahina ma hope o kāu hopena hope loa.
• inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o ka niho, e haʻi i ke kauka a i ʻole kauka niho paha e loaʻa ana iā ʻoe ka inikua polatuzumab vedotin-piiq.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

Inā haʻalele ʻoe i kahi manawa e loaʻa ai kahi mahele o polatuzumab vedotin-piiq, e kāhea koke aku i kāu kauka.

ʻO Polatuzumab vedotin-piiq ke kumu o nā hopena. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• pāhoehoe
• ka luaʻi
• ʻūpā
• nalo ʻai ʻole
• Kaumaha emi
• ʻeha pū

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻaoʻao HOW, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• huikau; palaho a nalowale paha o ke kaulike; paʻakikī i ke kamaʻilio ʻana a i ʻole ka hele wāwae ʻana; a i ʻole nā ​​hoʻololi ʻana i ka hihiʻo
• numbness a i ʻole ke kani ʻana o nā lima a me nā wāwae paha; aiʻole nāwaliwali o nā mākala, ʻeha, a ʻā paha
• paopao maʻalahi a hoʻokahe paha; kahe kahe mai ka gum a ka ihu; a i ʻole ke koko i ka mimi a i ʻole ka noho
• nausea, luaʻi, diarrhea, a me ka māluhiluhi
• ʻili mae a i ʻole ka luhi a ʻano ʻole paha
• fiva, ʻeha puʻu, ʻalalā, ʻeha ke hele ka mimi, a me nā ʻōuli ʻē aʻe o ka maʻi
• luhi nui loa; melemele o ka ʻili a i ʻole nā ​​maka; lilo o ka makemake ʻole; mimi ʻeleʻele; aiʻole kaʻeha ma kaʻaoʻao'ākau o luna o ka'ōpū

Hiki i nā ʻaoʻao ʻē aʻe i ka hopena ʻo Polatuzumab vedotin-piiq. Kāhea i kāu kauka inā loaʻa iā ʻoe kekahi pilikia maʻamau i ka loaʻa ʻana o kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha ke kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i ka inikua polatuzumab vedotin-piiq.

E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka polatuzumab vedotin-piiq injection.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Polivy^®