ʻO Acalabrutinib

Anter

• Ma mua o ka lawe ʻana i ka acalabrutinib,
• Hiki i ka Acalabrutinib ke hopena i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli e hōʻoki i ka lawe ʻana i ka acalabrutinib a kāhea koke aku i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

Hoʻohana ʻia ʻo Acalabrutinib e mālama i ka poʻe me ka limle cell lymphoma (MCL; kahi maʻi ʻaʻai e ulu wikiwiki ana e hoʻomaka i nā hunaola o ka ʻōnaehana pale) i mālama ʻia me hoʻokahi lāʻau chemotherapy ʻē aʻe. Hoʻohana pū ʻia ia a i ʻole me ka obinutuzumab (Gazyva) e mālama ai i ka leukemia lymphocytic mau (CLL; kahi ʻano maʻi ʻaʻai e hoʻomaka i nā kahe o ke koko keʻokeʻo) a me ka lympoma lymphocytic liʻiliʻi (SLL: kahi ʻano o ke kanesa e hoʻomaka i nā keokeo keʻokeʻo) . Aia ʻo Acalabrutinib i ka papa o nā lāʻau i kapa ʻia nā kinase inhibitors. Hana ia ma ke kāpae ʻana i ka hana o ka protein pono ʻole e hōʻailona ai i nā hunaola maʻi ʻaʻai e hoʻonui. Kōkua kēia i ka hōʻoki ʻana i nā hunaola maʻi ʻaʻai.

Hele mai ʻo Acalabrutinib ma ke ʻano he capsule e lawe ma ka waha. Lawe pinepine ʻia me a me ka ʻole o ka meaʻai i kēlā me kēia 12 hola (ʻelua manawa i ka lā) no ka mea ke koi aku kāu kauka e loaʻa iā ʻoe ka lāʻau. E lawe i ka acalabrutinib ma nā manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pono i ka acalabrutinib e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E hoʻopau piha i nā capsule me ke kīʻaha wai; mai wehe, nau, a wāwahi paha iā lākou.

Hiki i kāu kauka ke hoʻopau i kahi manawa kūlohelohe a paʻa paha i kāu lāʻau lapaʻau a hoʻoliʻiliʻi paha i kāu mahele lāʻau o acalabrutinib ma muli o nā ʻaoʻao i loaʻa iā ʻoe. E kamaʻilio pono i kāu kauka e pili ana i kou ʻano i kou wā e mālama ai. Mai hōʻoki i ka lawe ʻana i ka acalabrutinib me ka ʻole o ke kamaʻilio ʻana me kāu kauka.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka acalabrutinib,

• e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka acalabrutinib, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i ka capsule acalabrutinib. E noi i kāu kauka lāʻau a nānā paha i ka ʻike maʻi no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, nā mea hoʻopihaʻai, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe E hoʻomaopopo pono e ʻōlelo i nā lāʻau anticoagulant ('blood thinners') e like me warfarin (Coumadin); nā lāʻau antiplatelet ('blood thinners') e like me aspirin, cilostazol, clopidogrel (Plavix), dipyridamole (Persantine, in Aggrenox), prasugrel (Effient), ticagrelor (Brilinta), a me ticlodipine; diltiazem (Cardizem, Cartia, Diltzac, nā mea ʻē aʻe); erythromycin (E.E.S., Eryc, Erythrocin, nā mea ʻē aʻe); fluconazole (Diflucan); itraconazole (Onmel, Sporanox); nā mea hoʻopukapuka proton e like me dexlansoprazole (Dexilant), esomeprazole (Nexium, ma Vimovo), lansoprazole (Prevacid, ma Prevpac), omeprazole (Prilosec, ma Yosprala, Zegerid), pantoprazole (Protonix), a me rabeprazole (Aciphex); a me rifampin (Rifadin, Rimactane, ma Rifater, Rifamate). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Hiki paha i nā lāʻau ʻē aʻe ke launa pū me ka acalabrutinib, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau āpau āu e lawe nei, ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• inā ʻoe e lawe ana i ka cimetidine (Tagamet), famotidine (Pepcid, ma Duexis), nizatidine (Axid), a i ʻole ranitidine (Zantac) e lawe iā acalabrutinib ma kahi o 2 mau hola ma mua o ka lawe ʻana i kēia mau lāʻau.
• inā ʻoe e lawe i nā antacids (Maalox, Mylanta, Tums, a me nā mea ʻē aʻe) e lawe i ka acalabrutinib ma kahi o 2 mau hola ma mua a ma hope paha o ka lawe ʻana i kēia mau lāʻau.
• E haʻi i kāu kauka inā loaʻa ʻoe i ka maʻi a i ʻole ua ʻoki ʻia ʻoe i kēia manawa, a i ʻole inā ua loaʻa ʻoe i ka maʻi ate e like me ka hepatitis B, nā pilikia me kou puʻuwai puʻuwai, a i ʻole nā ​​pilikia kahe ʻana o ke kahe.
• e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. ʻAʻole pono ʻoe e hāpai i ka wā e lawe ana ʻoe i ka acalabrutinib. ʻAʻole pono ʻoe e hoʻomaka i ka lawe ʻana i ka acalabrutinib a hiki i ka hoʻāʻo ʻana o ka hāpai ʻana ua hōʻike ʻoe ʻaʻole ʻoe hāpai a pono ʻoe e hoʻohana i ka kaohi hānau e pale ai i ka hāpai ʻana i kāu wā lapaʻau a no 1 mau pule ma hope o kāu hopena hope loa. Hoʻopilikia paha ʻo Acalabrutinib i kāu pēpē i hānau ʻole ʻia. Inā hāpai ʻoe i ka lawe ʻana i ka acalabrutinib, e kāhea koke i kāu kauka.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. E haʻi paha kāu kauka iā ʻoe ʻaʻole e hānai i ka waiū i kou wā e mālama ai a no 2 mau pule ma hope o kāu hopena hope loa.
• inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o ka niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe ana ʻoe i ka acalabrutinib. E haʻi paha kāu kauka iā ʻoe e haʻalele i ka lawe ʻana i ka acalabrutinib no kekahi manawa ma mua a ma hope o ke ʻoki a me ke kaʻina hana.
• e hoʻolālā e hōʻalo i ka hōʻike kūpono ʻole a hoʻolōʻihi ʻia paha i ka lā a komo i nā lole pale, nā aniani aniani, a me ka sunscreen. Hiki i ka Acalabrutinib ke hana i kou ʻili i ka hopena weliweli o ka lā, a hoʻonui i kou makaʻu i ka ulu ʻana i ka maʻi ʻaʻai ʻili.

E kamaʻilio me kāu kauka e pili ana i ka ʻai ʻana i ka huaʻōlau a me ka inu ʻana i ka wai momona a ke lawe nei ʻoe i kēia lāʻau.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā ʻoi aku ma mua o ʻekolu mau hola i hala aku nei mai ka haʻina hala, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hiki i ka Acalabrutinib ke hopena i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• ʻeha poʻo
• nausea
• ka luaʻi
• kōpaʻa
• pāhoehoe
• abdominal eha
• hūwī
• ʻulupā māmā a ʻulaʻula ʻulaʻula a poni paha i ka ʻili
• ʻeha hui a ʻeha ʻeha paha
• luhi loa

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli e hōʻoki i ka lawe ʻana i ka acalabrutinib a kāhea koke aku i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• fiva, ʻeha ka ʻāʻī, haʻalulu, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi
• kahe, ka pōkole o ka hanu, ka ʻeha o ka umauma ke hanu ʻoe a i ʻole ka pī, fever
• ka wikiwiki a me ke kuʻi ʻole o ka puʻuwai, palpitations, ka uila a i ʻole ka puʻupuʻu, maʻule, pōkole o ka hanu, ʻeha o ka umauma.
• ʻano ʻē a koʻikoʻi paha i ke kahe ʻana a i ʻole nā ​​palapū
• ke koko i loko o kāu mau noho a ʻeleʻele paha, noho lōʻihi; mimi ʻulaʻula a ʻeleʻele paha; ka luaʻi ʻana i ke koko a i ʻole ka luaʻi kope lepo; kahe ana ke koko
• luʻuluʻu, nāwaliwali, a huikau paha; nā hoʻololi i ka ʻōlelo; ʻeha ke poʻo i lōʻihi loa

Hiki i ka Acalabrutinib ke hoʻonui i kou makaʻu i ka hoʻomohala ʻana i nā maʻi ʻē aʻe. E kamaʻilio me kāu kauka e pili ana i ka makaʻu i ka lawe ʻana i kēia lāʻau.

Hoʻokumu paha ʻo Acalabrutinib i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino iā acalabrutinib.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Calquence^®