ʻO Ledipasvir lāua ʻo Sofosbuvir

Anter

• Ma mua o ka lawe ʻana i ledipasvir a me sofosbuvir,
• Hiki i ka Ledipasvir a me ka sofosbuvir ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau pōpilikia.

Ua hele a maʻi paha ʻoe i ka maʻi hepatitis B (kahi maʻi i hoʻopili i ke ake a hōʻeha paha i ka ate), akā ʻaʻohe o nā ʻōuli o ka maʻi. I kēia hihia, ʻo ka lawe ʻana i ka hui pū ʻana o ledipasvir a me sofosbuvir e hoʻonui ai i ka makaʻu e hoʻomohala ʻoe i nā ʻōuli a e lilo kou maʻi i mea ʻoi aku a weliweli paha i ke ola E haʻi i kāu kauka inā ua loaʻa a loaʻa paha iā ʻoe ka maʻi hepitis B. E kauoha aku kāu kauka i kahi hoʻokolohua koko e ʻike inā loaʻa a loaʻa paha iā ʻoe i ka maʻi hepitis B. E nānā pū kāu kauka iā ʻoe no nā hōʻailona o ka maʻi hepatitis B i ka manawa a no kekahi mau mahina ma hope o kāu lapaʻau. Inā pono, hiki i kāu kauka ke hāʻawi iā ʻoe i ka lāʻau e mālama ai i kēia maʻi ma mua a i kou wā o ka mālama ʻana me ka hui pū ʻana o ledipasvir a me sofosbuvir. Inā ʻoe e ʻike i kekahi o nā ʻōuli ma hope a i ʻole a ma hope paha o kāu lapaʻau ʻana, e kāhea koke aku i kāu kauka: luhi nui, melemele o ka ʻili a i ʻole nā ​​maka, lilo i ka makemake ʻole, nausea, luaʻi, nā pale pale, ʻeha o ka ʻōpū, a me ka mimi ʻeleʻele.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. Hiki paha i kāu kauka ke kauoha i kekahi mau hoʻokolohua ma mua, i ka wā, a ma hope o kāu mālama ʻana e nānā i ka pane o kou kino i ka hui pū ʻana o ledipasvir a me sofosbuvir.

E kamaʻilio me kāu kauka e pili ana i ka makaʻu (s) o ka lawe ʻana i ka hui pū o ledipasvir a me sofosbuvir.

Hoʻohana hoʻokahi ʻia ka hui pū ʻana o ledipasvir a me sofosbuvir a i ʻole hui pū ʻia me ribavirin (Copegus, Rebetol, Ribasphere, a me nā mea ʻē aʻe) e mālama i kekahi ʻano o ka hepatitis C mau (kahi maʻi viral e hoʻomau nei e hōʻino ai i ke ake) i nā mākua a me nā keiki he 3 mau makahiki a ʻoi paha. ʻelemakule. Aia ʻo Sofosbuvir i loko o ka papa o nā lāʻau antiviral i kapa ʻia he mau mea kāohi nāukana nukleotide. Hana ia ma ka hoʻemi ʻana i ka nui o ka maʻi hepitis C (HCV) i ke kino. Aia ʻo Ledipasvir i loko o ka papa o nā lāʻau antiviral i kapa ʻia nā mea kāohi iā HCV NS5A. Hana ia ma ka hoʻōki ʻana i ka maʻi nāna i hoʻokumu i ka maʻi hepitis C mai ka hoʻolaha ʻana i loko o ke kino.

ʻO ka hui pū ʻana o ledipasvir a me sofosbuvir e hele mai ana ma ke ʻano he papa a me nā pelele e lawe ʻia e ka waha. Lawe mau ʻia me ka ʻai ʻole a ʻai ʻole hoʻokahi manawa i kēlā me kēia lā. Lawe i ka ledipasvir a me ka sofosbuvir ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pono iā ledipasvir a me sofosbuvir e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

Hiki ke ale ʻia ʻo Ledipasvir a me nā pellets sofosbuvir (me ka nau ʻole) a i ʻole hiki ke lawe ʻia me ka meaʻai. E hoʻomākaukau i kahi mahele o nā ledipasvir a me nā pellets sofosbuvir me ka meaʻai, e kāpīpī i ka pūʻolo pellets āpau ma hoʻokahi a ʻoi mau punetē o ke anuanu a me nā lumi wela ʻole nā ​​meaʻai momona like ʻole e like me ka pudding, syrup syrup, ʻuala palu, a me ka ʻaikalima. Lawe i ka hui holoʻokoʻa ma waena o 30 mau minuke o ka pīpī ʻana i nā pellets i ka meaʻai. I mea e hōʻalo ai i ka ʻawaʻawa hope, mai nāhelehele i nā pellets.

E hoʻomau i ka lawe i ka ledipasvir a me ka sofosbuvir ʻoiai inā maikaʻi ʻoe. ʻO ka lōʻihi o kāu mālama ʻana (8 a 24 mau pule) pili i kou ʻano, pehea kou pane ʻana i ka lāʻau, a inā ʻoe e ʻike i nā hopena ʻino. Mai hoʻōki i ka lawe ʻana i ledipasvir a me sofosbuvir me ke kamaʻilio ʻole ʻana me kāu kauka.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ledipasvir a me sofosbuvir,

• e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka ledipasvir a i ʻole sofosbuvir, nā lāʻau ʻē aʻe, a i ʻole nā ​​mea hana i ka ledipasvir a me nā sofosbuvir papa a i ʻole nā ​​pellets. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, a me nā mea hoʻopihaʻai pono ʻole āu e lawe nei a hoʻolālā paha e lawe. E haʻi pono i kekahi o kēia mau mea: amiodarone (Nexterone, Pacerone); digoxin (Lanoxin); kekahi mau lāʻau no ka maʻi ʻaʻai; nā lāʻau no ka maʻi kō; kekahi mau lāʻau no ka hopu ʻana e like me carbamazepine (Carbatrol, Epitol, Equetro, Tegretol), oxcarbazepine (Oxtellar XR, Trileptal), phenobarbital, a i ʻole phenytoin (Dilantin, Phenytek); nā lāʻau lapaʻau no ka ʻāʻī ʻana o ka puʻuwai a me nā ulcer; lawe ʻia nā lāʻau no ka HIV e like me efavirenz (Sustiva, i Atripla), emtricitabine (Emtriva, i Atripla) a me tenofovir (Viread, i Atripla); elvitegravir (Sustiva, ma Atripla), cobicistat (Tybost, ma Stribild), emtricitabine (Emtriva, ma Stribild), a me tenofovir (Viread, ma Stribild); tenofovir (Viread), atazanavir (Reyataz) a me ritonavir (Norvir); tenofovir (Viread), darunavir (Prezista) a me ritonavir (Norvir); tenofovir (Viread), lopinavir (in Kaletra), and ritonavir (Norvir, in Kaletra); a i ʻole tipranavir (Aptivus) a me ritonavir (Norvir); kekahi mau lāʻau e kāohi i ka ʻōnaehana pale maʻi; rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, ma Rifamate, ma Rifater); rifapentine (Priftin); rosuvastatin (Crestor); simeprevir (Olysio); sofosbuvir (Sovaldi); a me warfarin (Coumadin, Jantoven). E ʻōlelo paha kāu kauka iā ʻoe ʻaʻole e lawe i ka ledipasvir a me ka sofosbuvir inā ʻoe e lawe ana i hoʻokahi a ʻoi paha o kēia mau lāʻau a i ʻole e nānā pono iā ʻoe no nā hopena ʻaoʻao. Nui paha nā lāʻau ʻē aʻe e launa pū me ledipasvir a me sofosbuvir, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• inā ʻoe e lawe i nā antacids i loko o ka aluminium hydroxide a i ʻole magnesium hydroxide (Maalox, Mylanta, Tums, a me nā mea ʻē aʻe), lawe iā lākou i 4 mau hola ma mua a i ʻole 4 mau hola ma hope o ka lawe ʻana i ledipasvir a me sofosbuvir.
• e haʻi i kāu kauka inā e lawe ana ʻoe i ka lāʻau no ka palaka ʻole ʻana, ka ʻū ʻana o ka puʻuwai, a i ʻole nā ​​maʻi maʻi hē₂ blockers) e like me cimetidine, ranitidine (Zantac), famotidine (Pepcid, i ka Afterxis) a i ʻole nizatidine. E haʻi paha kāu kauka iā ʻoe e lawe iā lākou i 12 mau hola ma mua a i ʻole 12 mau hola ma hope o ka ledipasvir a me ka sofosbuvir, a i ʻole ma ka manawa like e lawe ai ʻoe i ledipasvir a me sofosbuvir.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St. ʻAʻole pono ʻoe e lawe i ka wort a St. John i kou wā e mālama ai me ledipasvir a me sofosbuvir.
• e haʻi i kāu kauka inā loaʻa iā ʻoe kahi hoʻoliʻiliʻi ate a inā loaʻa iā ʻoe kahi maʻi pale maʻi (HIV) kanaka. Eia kekahi, e haʻi i kāu kauka inā loaʻa a loaʻa paha ʻoe i kekahi ʻano maʻi maʻi akepae ma mua o ka hepatitis C, ka maʻi puʻuwai, a i ʻole ke dialysis.
• e haʻi i kāu kauka inā hāpai ʻoe, hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Inā hāpai ʻoe i ka lawe ʻana i ledipasvir a me sofosbuvir, e kāhea i kāu kauka. Inā hoʻohana ʻia ʻo ledipasvir a me sofosbuvir i ka hui pū ʻia me ka ribavirin, e heluhelu pono i ka ʻike e pili ana i ka mālama ʻana i ka hāpai ʻana ma ka monarch ribavirin.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hiki i ka Ledipasvir a me ka sofosbuvir ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• luhi
• ʻeha poʻo
• paʻakikī e hiamoe a hiamoe paha
• nausea
• pāhoehoe
• ʻūhā
• ʻūpā
• ʻeha mākala
• ukiuki

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau pōpilikia.

• hūwī
• ʻōhū
• pehu o ka maka, lima a mau wāwae paha
• pokole o ka hanu
• hulahula
• pilikia i ka ale ʻana a me ka hanu ʻana

Hiki iā Ledipasvir a me sofosbuvir ke hana i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. Mai hoʻohana inā haki a nalowale paha ke sila ma ka wehe ʻana o ka hue. E mālama iā ia i ka mahana wela o ka lumi a mamao aku mai ka mālamalama, ka wela a me ka momona o ka wela (ʻaʻole i loko o ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Harvoni^®