Dolutegravir
Anter
- Ma mua o ka lawe ʻana i ka dolutegravir,
- Hoʻokumu paha ʻo Dolutegravir i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
- Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā mea i helu ʻia i ka ʻĀLU MAKAHIKI kūikawā, e hoʻōki i ka lawe ʻana i ka dolutegravir a kāhea koke aku i kāu kauka a i ʻole e kiʻi i ka lāʻau lapaʻau pilikia.
Hoʻohana ʻia ʻo Dolutegravir me nā lāʻau ʻē aʻe e mālama i ka maʻi maʻi (HIV) kanaka i nā mākua a me nā keiki he 4 mau makahiki o ka makahiki a ʻoi aku ka nui o 6.6 lbs (3 kg). Hoʻohana pū ʻia ia me ka rilpivirine (Edurant) e mālama i ka maʻi HIV i kekahi mau mākua e pani i kā lākou mau lāʻau HIV i kēia manawa i lawe ʻia no 6 mau mahina. Aia ʻo Dolutegravir i kahi papa o nā lāʻau i kapa ʻia ʻo nā mea hoʻopili ʻo HIV integrase. Hana ia ma ka hoʻemi ʻana i ka nui o ka maʻi HIV i kou koko a hoʻonui i ka nui o nā hunaola i kōkua i ke kaua ʻana i nā maʻi i kou kino. ʻOiai ʻaʻole hiki i ka dolutegravir ke hoʻōla i ka maʻi HIV, ka hoʻohana ʻana ia me nā lāʻau ʻē aʻe e hoʻemi i kou manawa o ka hoʻomohala ʻia ʻana o ka maʻi maʻi maʻi (AIDS) a me nā maʻi e pili ana i ka maʻi HIV e like me nā maʻi nui a i ʻole ke kanesa. ʻO ka lawe ʻana i kēia mau lāʻau a me ka hoʻomaʻamaʻa ʻana i ka moekolohe ʻoi aku ka maikaʻi a me ka hoʻololi ʻana i nā ʻano nohona ʻē aʻe e hōʻemi paha i ka lawe ʻana (hoʻolaha) i ka maʻi HIV i kekahi poʻe ʻē aʻe.
Hele mai ʻo Dolutegravir ma ke ʻano he papaha a ma ke ʻano he papa no ke kau ʻana (kahi papa e hoʻoheheʻe ʻia i ka wai) e lawe ʻia e ka waha. Lawe pinepine ia hoʻokahi a ʻelua paha i ka lā me ka ʻai ʻole. Lawe i ka dolutegravir ma kahi o ka manawa like (s) i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe i ka dolutegravir e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.
Mai ʻoki, ʻoki, a ʻokiʻoki i nā papa no ka hoʻolōʻihi ʻia ʻana o ka waha. Hiki iā ʻoe ke ale i ka papa holoʻokoʻa, hoʻokahi i ka manawa, a hui pū paha me ka wai inu ma mua o ka hoʻohana.
Inā ʻoe e kāwili i nā papa no ka hoʻolōʻihi ʻia ʻana o ka waha i ka wai inu, e hoʻohui i ka helu i kau ʻia o nā papa (s) i kahi kīʻaha dosing. Inā lawe i ka 1 a i ʻole 3 mau (s) no ka hoʻokuʻu waha, e hoʻohui i 1 teaspoon (5 mL) o ka wai inu i ke kīʻaha. Inā lawe i ka 4, 5, a i ʻole 6 mau papa no ka hoʻolōʻihi ʻia ʻana o ka waha, e hoʻohui i 2 teaspoons (10 mL) o ka wai inu i ke kīʻaha. Mai hoʻohana i kekahi wai ʻē aʻe e hoʻonā i ka papa. E kolo i ke kīʻaha no 1 a i ʻole 2 mau minuke a i ka wā e pau ai ka hui ʻana; ʻōpua ka piʻo. Ke pau ka papa (s) no ka hoʻomaha loa, e inu i ka hui ma hope o ka hoʻowili ʻia ʻana. Inā ʻoi aku ma mua o 30 mau minuke ma hope o ka hoʻohuihui ʻia ʻana, hoʻolei i ka hui.
Inā hāʻawi i nā papa no ka hoʻohuihui kāwili ʻia i kahi keiki, e nānā pono inā kū pololei ʻo ia i ka lawe ʻana iā ia. Inā he koena i koe i loko o ke kīʻaha, e hoʻomoʻi i kahi teaspoon (5 ML) o ka wai inu i ke kīʻaha, e ʻāwīwī, a hāʻawi i ke keiki āpau e ʻike pono i ka loaʻa ʻana o ke koina piha.
Inā hāʻawi i nā papa no ka hoʻohuihui kāwili ʻia i kahi pēpē, e hoʻohana i ka syringe waha i hāʻawi ʻia e ana a hāʻawi i ka lāʻau. E kau i ka piko o ka syringe i loko o ke kīʻaha dosing me ka huikau i hoʻomākaukau ʻia e huki ai i ka syringe. E kau i ka piko o ka ʻekika waha i ka waha o ke keiki e kūʻē i ka ʻaoʻao o ka papalina. E kaomi mālie i ka plunger e hāʻawi mālie i ka lāʻau. E hāʻawi i ka manawa no ka pēpē e ale i ka hui. Hoʻohui i kahi teaspoon (5 mL) o ka wai inu i ke kīʻaha a huli.E huki i ka hui i koe i loko o ka syringe a hāʻawi i nā keiki āpau. E hana hou inā mau kekahi o nā mea hoʻohui i ka syringe e ʻike pono i ka loaʻa ʻana o ka pēpē i ke keiki. E hāʻawi ʻia ka hui ʻana i ka pēpē i loko o 30 mau minuke o ka hoʻohuihui ʻana. Ma hope o ka mahele lāʻau, holoi i ke kīʻaha a me nā ʻāpana syringe i kahi kaʻawale me ka wai. E ʻae i nā ʻāpana e maloʻo loa ma mua o ka hoʻopili hou ʻana a me ka mālama ʻana.
Mai hoʻololi i nā papa i nā papa (s) no ka hoʻomaha ʻana me ka ʻole o ke kamaʻilio mua ʻana me kāu kauka.
E hoʻomau i ka lawe i ka dolutegravir ʻoiai ʻoe e manaʻo maikaʻi. Mai hōʻoki i ka lawe ʻana i ka dolutegravir me ke kamaʻilio ʻole ʻana me kāu kauka. Ke holo haʻahaʻa kāu lako o dolutegravir, e kiʻi hou aʻe mai kāu kauka a kauka paha. Inā kū ʻoe i ka lawe ʻana i ka dolutegravir a i ʻole nalo ʻana i nā lāʻau, e ʻoi aku paha ka maikaʻi o kou maʻi a ʻoi aku ka paʻakikī e mālama me ka lāʻau.
E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.
Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.
Ma mua o ka lawe ʻana i ka dolutegravir,
- e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka dolutegravir, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i loko o ka papa dolutegravir. E noi i kāu kauka lāʻau a nānā paha i ka ʻike hoʻomanawanui o ka mea hana no kahi papa inoa o nā mea hoʻohui.
- E haʻi i kāu kauka inā lawe ʻoe i dofetilide (Tikosyn). E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka dolutegravir inā ʻoe e lawe i kēia lāʻau.
- e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā huaora, a me nā mea hoʻopihaʻai pono ʻole e lawe ai. E ʻōlelo pono i kekahi o kēia mau mea: dalfampridine (Ampyra); nā lāʻau lapaʻau ʻē aʻe no HIV e like me efavirenz (Sustiva, i Atripla), etravirine (Intelence), fosamprenavir (Lexiva) i lawe ʻia me ritonavir (Norvir), nevirapine (Viramune), a me tipranavir (Aptivus) i lawe ʻia me ritonavir (Norvir); kekahi mau lāʻau no ka hopu ʻana e like me carbamazepine (Carbatrol, Equetro, Tegretol), oxcarbazepine (Oxtellar XR, Trileptal), phenobarbital, a me phenytoin (Dilantin, Phenytek); metformin (Glumetza, Glucophage, Riomet); a me rifampin (Rifadin, Rimactane, ma Rifamate, ma Rifater). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
- inā ʻoe e lawe i nā antacids, laxatives, a i ʻole multivitamins i loaʻa ka aluminika, ka magnesium, a me ka calcium; pākuʻi kalipuna; pākuʻi hao; sucralfate (Carafate); aiʻole nā lāʻau i hoʻopili ʻia e like me buffirin aspirin, lawe iā lākou i 2 mau hola ma hope a i ʻole 6 mau hola ma mua o kou lawe ʻana i ka dolutegravir. Eia nō naʻe, inā ʻoe e lawe i ka dolutegravir me ka meaʻai, lawe paha ʻoe i kēia mau mea hoʻopiha i ka manawa like e lawe ai ʻoe i ka dolutegravir.
- e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St.
- e haʻi i kāu kauka inā loaʻa ʻoe a i ʻole loaʻa i ka maʻi puʻupaʻa a i ʻole e loaʻa ʻana i nā lāʻau dialysis a i ʻole nā maʻi ate me ka maʻi hepatitis B a i ʻole hepatitis C.
- e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. Pono ʻoe e lawe i kahi hōʻike hāpai ma mua o kou hoʻomaka ʻana i ka lāʻau. E kamaʻilio me kāu kauka e pili ana i nā ʻano hana hānau hānau hiki iā ʻoe ke hoʻohana i kāu wā o kāu mālama ʻana. Inā hāpai ʻoe i ka lawe ʻana i ka dolutegravir, e kāhea koke i kāu kauka. Hoʻopilikia paha ʻo Dolutegravir i ka fetus.
- e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. ʻAʻole pono ʻoe e hānai i ka hānai inā loaʻa ʻoe i ka maʻi HIV a inā ʻoe e lawe i ka dolutegravir.
- pono ʻoe e ʻike ʻoiai ʻoe e lawe nei i nā lāʻau e mālama ai i ka maʻi HIV, e ikaika paha kou ʻōnaehana pale a hoʻomaka e hakakā i nā maʻi ʻē aʻe i loko o kou kino. Hiki iā ʻoe ke hoʻomohala i nā ʻōuli o kēlā mau maʻi. Inā loaʻa iā ʻoe nā hōʻailona hou a pōʻino paha ma hope o ka hoʻomaka ʻana o ka mālama ʻana me dolutegravir, e ʻike pono i kāu kauka.
Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.
E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.
Hoʻokumu paha ʻo Dolutegravir i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
- paʻakikī e hiamoe a hiamoe paha
- ʻeha poʻo
- ʻeha ka ʻōpū
- ʻenekini
- pāhoehoe
- loaʻa kaupaona
Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā mea i helu ʻia i ka ʻĀLU MAKAHIKI kūikawā, e hoʻōki i ka lawe ʻana i ka dolutegravir a kāhea koke aku i kāu kauka a i ʻole e kiʻi i ka lāʻau lapaʻau pilikia.
- hūwī
- fiva
- manaʻo maʻi
- luhi nui loa
- ʻehaʻeha a ʻeha pū paha
- ʻili a ʻiliʻili paha
- pāhū a ʻeha paha i ka waha
- ʻulaʻula a pehu paha nā maka
- pehu o nā maka, maka, lehelehe, waha, elelo, a ʻāʻī paha
- pilikia i ka hanu ʻana a i ʻole ke ale ʻana
- melemele o nā maka a ʻili paha
- mimi ʻeleʻele
- ʻōniʻoniʻo ʻōniʻoniʻo keʻokeʻo
- nausea
- ka luaʻi
- nalo ʻai ʻole
- ʻeha ma ka ʻaoʻao ʻākau o luna o ka ʻōpū
Hoʻokumu paha ʻo Dolutegravir i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.
Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).
E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua. Mai wehe i ka desiccant (ʻāpana ʻuʻuku e loaʻa ka mea i omo i ka wai e mālama i ka lāʻau i maloʻo) mai ka ʻōmole.
He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org
Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.
I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.
E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha paha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i ka dolutegravir.
E mālama i kahi lako o dolutegravir ma ka lima. Mai kali a hiki i ka pau ʻana o kāu lāʻau e hoʻopiha hou i kāu kuhikuhi.
Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.
He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.
- ʻO Tivicay®
- ʻO Tivicay® PD
- ʻO Juluca® (ma ke ʻano he huahana hoʻohui ʻia me dolutegravir, rilpivirine)